Psycho‐Oncology最新文献

{"title":"Psychosocial Needs of People Living With Pleural Mesothelioma and Family Carers: A Mixed Methods Study.","authors":"Lauren J Breen, Anne Same, Carolyn J Peddle-McIntyre, Calvin Sidhu, Deirdre Fitzgerald, Ai Ling Tan, Renee N Carey, Chanelle Wilson, Y C Gary Lee","doi":"10.1002/pon.70031","DOIUrl":"https://doi.org/10.1002/pon.70031","url":null,"abstract":"<p><strong>Background: </strong>Mesothelioma is a cancer of growing global incidence, especially in developing countries, with unique complex psychosocial impacts on patients and their carers.</p><p><strong>Aims: </strong>To provide a comprehensive understanding of the psychosocial needs of people living with pleural mesothelioma and family carers.</p><p><strong>Methods: </strong>A mixed methods design with 61 semi-structured interviews and psychometrically validated questionnaires to assess pleural mesothelioma patients' (n = 36) quality of life and frailty and carers' (n = 25) caregiving experiences, quality of life, and pre-loss prolonged grief symptoms.</p><p><strong>Results: </strong>People with mesothelioma (29 men, 7 women, aged 46-89 years) indicated moderate quality of life; 18 (50%) met criteria for frailty. Current carers (21 women, 4 men; aged 41-79 years) generally reported positive caregiving experiences and high quality of life; 5 (20%) scored in the range indicative of risk for prolonged grief disorder. Four themes were generated: a desire for tailored information with bespoke detail, assistance to coordinate tasks of treatment, improved social and peer support, and effective psychological services. Needs varied, with main concerns being about breaking the news to spouses/children, the impact of the disease and death on family, loss of personal future, managing psychological symptoms, and avoiding burden.</p><p><strong>Conclusions: </strong>These specific and unmet psychosocial needs provide a strong basis for individualised care pathways to address these needs via the integration of psychology into the multidisciplinary care team and the development and evaluation of mental health and wellbeing interventions for mesothelioma patients and carers. Doing so will reduce psychosocial distress and improve residual vitality.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 11","pages":"e70031"},"PeriodicalIF":3.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142626855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Supportive Care Needs of Individuals Living With Advanced or Metastatic Lung Cancer Receiving Targeted or Immunotherapies.","authors":"Emma Kearns, Alanna K Chu, Rinat Nissim, Paul Wheatley-Price, Tim Aubry, Sophie Lebel","doi":"10.1002/pon.70015","DOIUrl":"https://doi.org/10.1002/pon.70015","url":null,"abstract":"<p><strong>Objective: </strong>Lung cancer is associated with the highest incidence and mortality of all cancers. New treatments, called targeted therapies (TT) and immunotherapies (IO), offer higher treatment efficacy and fewer side effects compared to traditional treatments but are accompanied by uncertainty and an unpredictable treatment course. There is a paucity of research on the experiences of individuals living with advanced or metastatic lung cancer receiving TT/IO, and even less is known about the supportive care needs of this population.</p><p><strong>Methods: </strong>Twenty four participants from across Canada participated in semi-structured interviews regarding their supportive care needs. Thematic analysis was utilized to identify their supportive care needs.</p><p><strong>Results: </strong>Qualitative coding identified unmet needs and challenges. All participants indicated difficulties with unmet supportive care needs, including psychological, informational, and practical needs.</p><p><strong>Conclusions: </strong>The exploration of supportive care experiences of patients receiving TT/IO exposes high distress and unmet needs. Results indicate the need for timely and accessible supportive cancer care. Results can inform patient advocacy efforts and the development of new services.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 11","pages":"e70015"},"PeriodicalIF":3.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Psychometric Testing of the Existential Distress Scale for Palliative Care Cancer Patients.","authors":"Ying Chen, Guojuan Chen, Jianwei Zheng, Huimin Xiao","doi":"10.1002/pon.70016","DOIUrl":"https://doi.org/10.1002/pon.70016","url":null,"abstract":"<p><strong>Objective: </strong>Existential distress is a common phenomenon in palliative care cancer patients. Developing a reliable and easy-to-use assessment scale for existential distress of palliative care cancer patients is crucial. The aim of this study was to develop a measurement of existential distress for palliative care cancer patients and test its properties.</p><p><strong>Methods: </strong>The guidelines for developing a scale proposed by DeVellis were followed. Palliative care cancer patients were invited to test the draft scale. Two-hundred and nineteen valid questionnaires were included for the item analysis and exploratory factor analysis. Three-hundred and two valid questionnaires were included for confirmatory factor, convergent validity, discriminant validity, and internal consistency reliability analyses. Twenty repeated data were measured for test-retest reliability analysis.</p><p><strong>Results: </strong>The Existential Distress Scale for Palliative Care Cancer Patients was developed with nine items and three dimensions, including meaninglessness, alienation, and death anxiety. The confirmatory factor analysis showed that the developed scale had a stable factor structure. The Cronbach's α for the whole scale was 0.81, and that for each dimension was 0.76, 0.67, and 0.70, respectively. The test-retest reliability of the scale was 0.79, and that of each dimension was 0.58-0.64.</p><p><strong>Conclusions: </strong>The Existential Distress Scale for Palliative Care Cancer Patients is a simple but reliable and valid tool.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 11","pages":"e70016"},"PeriodicalIF":3.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142564841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measuring Self-Efficacy to Request Cancer-Related Work Accommodations: Development and Validation of a Brief Survey Instrument.","authors":"Victoria Blinder, Jada G Hamilton, Carolyn Eberle, Jackie Finik, Bharat Narang, Rose C Maly, Francesca Gany, Sujata Patil","doi":"10.1002/pon.70028","DOIUrl":"10.1002/pon.70028","url":null,"abstract":"<p><strong>Objective: </strong>Access to work accommodations, such as time off to attend medical appointments, is a key predictor of cancer-related job loss. We aimed to develop and validate a measure of self-efficacy to request and obtain work accommodations related to diagnosis of breast cancer and need for treatment.</p><p><strong>Methods: </strong>The 5-item Self-efficacy to Ask for Work Accommodations (SAWA) tool was adapted from a scale that measures self-efficacy in patient-physician interactions. English-speaking, employed women, aged 18-64, who were undergoing treatment for stage I-III breast cancer completed surveys during treatment (chemotherapy, radiation, and/or < 60 days since surgery) and 4 months after its completion. Post-treatment surveys were the primary validation dataset; analyses were repeated using baseline data to further evaluate validity/reliability. Psychometric analyses included internal consistency, principal component factor analysis, convergent and divergent validity, and test-retest reliability (in a subset of patients, 2 weeks after post-treatment surveys).</p><p><strong>Results: </strong>Among 362 participants, the SAWA measure had a Cronbach's alpha of 0.93, indicating high scale reliability. Factor analysis revealed one summary measure which could be divided into two subscales. Overall, the SAWA demonstrated convergent and divergent validity based on the hypothesized variables. Similar patterns were observed when analyses were repeated using baseline survey data. In the test-retest subset, the Pearson correlation between SAWA assessed 4 months post-treatment versus retest 2 weeks later was 0.79.</p><p><strong>Conclusions: </strong>The SAWA is a validated survey instrument that can be used to measure self-efficacy in employed cancer patients to ask for and obtain employment accommodations.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 11","pages":"e70028"},"PeriodicalIF":3.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11730020/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social Support, Social Strain, Stressful Life Events and Mortality Among Postmenopausal Women With Breast Cancer.","authors":"Fengge Wang, Michael S Simon, Candyce H Kroenke, Jessica Krok-Schoen, Su Yon Jung, Rowan Chlebowski, Tarah J Ballinger, Margaret S Pichardo, Mace Coday, Lorena Garcia, Juhua Luo","doi":"10.1002/pon.70013","DOIUrl":"https://doi.org/10.1002/pon.70013","url":null,"abstract":"<p><strong>Introduction: </strong>Social support, social strain and stressful life events could induce chronic stress, which affects prognosis and survival after breast cancer diagnosis. However, few studies have examined the impact of psychosocial factors on different competing mortality events.</p><p><strong>Methods: </strong>We included 9154 postmenopausal women who were newly diagnosed with invasive breast cancer after enrollment in the Women's Health Initiative, as of March 6th, 2021. Psychosocial factors were collected and stratified into quartiles. Cause of death was verified through adjudicated medical record reviews. Associations between psychosocial factors and all-cause mortality, breast cancer mortality, and cardiovascular disease mortality were examined by competing risk models. Subsequent stratified analyses were performed by race.</p><p><strong>Results: </strong>With a median follow-up time of 8.6 years, 3218 deaths were identified. Compared to participants with less social support, those who had higher social support had significantly lower all-cause mortality (Q4 vs. Q1, HR = 0.89, 95% CI: 0.81, 0.9). The highest quartile of social strain was associated with lower CVD mortality (Q4 vs. Q1: HR = 0.80, 95% CI: 0.65, 0.99). After stratification, a similar relationship was found in White women but not in Black women.</p><p><strong>Conclusion: </strong>Our findings suggest that there was an association between high social support and reduced all-cause mortality regardless of cancer stages at diagnosis. Social support interventions after breast cancer diagnosis could have the potential to reduce overall mortality.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 11","pages":"e70013"},"PeriodicalIF":3.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142626857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing a Training Program for Integrative Medicine Practitioners in the Treatment of Acute Stress Disorder.","authors":"Eran Ben-Arye, Dori Rubinstein, Gali Stoffman, Mooli Lahad, Noah Samuels, Alon Reshef, Elad Schiff","doi":"10.1002/pon.70022","DOIUrl":"https://doi.org/10.1002/pon.70022","url":null,"abstract":"<p><strong>Study objective: </strong>The study examined a training program for integrative medicine (IM) providers, teaching clinical skills for treating acute stress disorder (ASD).</p><p><strong>Methods: </strong>A 10-h online training program, designed by IM and mental health professionals, was attended by a group of 32 IM providers working in supportive and palliative oncology care. Pre- and post-course questionnaires assessed self-perceived levels of IM and mental health ASD-related skills (from 1, very low; to 7, very high).</p><p><strong>Results: </strong>Most participants (25; 78%) completed pre- and post-study questionnaires, which showed an increase in post-course scores for the expectation that IM could reduce ASD-related pain (p = 0.004). Scores for self-assessed skill levels increased for treating gastro-intestinal symptoms and appetite (p = 0.039) and for dyspnea (p = 0.048). A borderline increase for arousal was observed (p = 0.063), with no increase with other arousal symptom cluster symptoms.</p><p><strong>Conclusions: </strong>The ASD-focused training program for IM practitioners was associated with an increase in self-perceived levels for related clinical skills quality of life-related concerns, primarily pain, appetite and dyspnea. Further research is needed to better understand the implications of the findings, and to explore the implementation of the learned skills in clinical practice.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 11","pages":"e70022"},"PeriodicalIF":3.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142626853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personality Feedback With Tailored Self-Care Recommendations Improves Self-Efficacy for Cancer Management: A Randomized Controlled Trial.","authors":"Laura M Perry, Brenna Mossman, Sofia F Garcia, Sheetal M Kircher, Addison Dunn, Sarah Alonzi, Sanjana Easwar, Michael Hoerger","doi":"10.1002/pon.70023","DOIUrl":"10.1002/pon.70023","url":null,"abstract":"<p><strong>Objective: </strong>To test whether a personality feedback intervention improves three domains of cancer self-management: self-awareness, self-efficacy, and positive affect.</p><p><strong>Methods: </strong>From 11/2020-02/2021, 372 adults diagnosed with cancer participated in a randomized controlled trial (RCT) of an intervention that entailed reading a brief personality-related excerpt during an online survey. Eligibility included self-reported age ≥ 18 years, current or past cancer diagnosis, and ability to read English. The survey included a baseline assessment with a personality questionnaire, then randomized participants to one of two groups. The intervention group (n = 184) received a personality feedback report with tailored self-care tips, whereas the control group (n = 188) received a generic reading on personality theory. At the end of the survey, participants completed outcome measures of self-awareness (primary), self-efficacy for illness management, and positive affect. General linear models tested between-group differences in changes from baseline to post-test on each outcome.</p><p><strong>Results: </strong>There was no intervention effect on self-awareness (primary outcome) or positive affect. However, compared to controls, intervention participants experienced a greater increase in self-efficacy for illness management (d = 0.33, p = 0.002), including in 2 of 3 constituent domains: self-efficacy for managing symptoms (d = 0.36, p < 0.001) and self-efficacy for managing treatments/medication (d = 0.22, p = 0.035).</p><p><strong>Conclusion: </strong>Despite the primary outcome's null results, this was the first RCT of a personality feedback intervention to show improvements in self-efficacy for managing chronic illness. Given the important role of self-efficacy in self-management, the intervention has implications for other cancer outcomes. Follow-up studies on longer-term outcomes such as health behaviors and quality of life should be explored.</p><p><strong>Trial registration: </strong>NCT04625439.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 11","pages":"e70023"},"PeriodicalIF":3.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Characteristics and Care Trajectories of Transgender and Gender Diverse Patients With Cancer Seen in a Pediatric Gender Clinic.","authors":"Madeline H Bono, Hannah L Smith, Coleen R Williams, Kerry McGregor, Ariel K Berman, Elizabeth R Boskey","doi":"10.1002/pon.70017","DOIUrl":"https://doi.org/10.1002/pon.70017","url":null,"abstract":"<p><strong>Background: </strong>There is very little information on the experiences of transgender and gender diverse (TGD) youth with cancer.</p><p><strong>Aims: </strong>To examine clinical characteristics and care trajectories of TGD youth a history of cancer.</p><p><strong>Methods: </strong>This case series reviewed records of 2790 pediatric gender clinic patients seen between 2007 and 2022 to identify 14 with a history of cancer diagnosis. Demographics, clinical characteristics, disclosure of gender identity to oncology teams, oncology teams' use of correct names and pronouns, documented interprofessional communication between gender health and oncology teams, and course of medical gender affirmation were reviewed.</p><p><strong>Results: </strong>Of 14 TGD youth with a history of cancer, 11 (78.6%) were diagnosed prior to presenting to the gender clinic (mean [SD] = 8.2 [4.7] years), three following initial gender care (mean [SD] = 1.1 [0.2] years). Six (42.9%) patients were engaged in annual survivorship care when presenting, and 8 (57.1%) were seen concurrently by both clinics. Nine (64.3%) patients had documented communication between teams. Three-quarters of patients who were seen concurrently by both clinics had documented interprofessional communication. Eight (57.1%) patients received gender affirming hormones, after cancer treatment concluded.</p><p><strong>Conclusion: </strong>TGD youth with cancer experiences present for gender affirming care and merit clinical attention. There was variability in (1) patients' and families' disclosure of TGD identities to oncology teams, (2) whether oncology documentation consistently used patients' correct name and pronouns, and (3) whether there was documented interprofessional consultation between teams. There is need for ongoing improvement in research and clinical protocols for TGD youth with cancer.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 11","pages":"e70017"},"PeriodicalIF":3.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142591346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceived Control as a Potential Protective Factor for Suicidal Thoughts and Behaviors in Cancer Patients and Survivors: A Systematic Review With Meta-Analysis.","authors":"Judith Hirschmiller, Jim Schmeckenbecher, Tamara Schwinn, Jörg Wiltink, Elmar Brähler, Nestor Kapusta, Rüdiger Zwerenz, Manfred E Beutel, Mareike Ernst","doi":"10.1002/pon.70030","DOIUrl":"10.1002/pon.70030","url":null,"abstract":"<p><strong>Objective: </strong>Individuals affected by cancer have an elevated risk of experiencing suicidal crises. Aligning established suicide theories with social-cognitive theories, perceived control and related constructs emerge as potential protective factors for suicidal thoughts and behaviors in cancer patients. As perceived control is potentially modifiable, it holds great potential for prevention and intervention efforts. We aimed to comprehensively synthesize the evidence on perceived control and its link with suicidal thoughts and behaviors in cancer patients.</p><p><strong>Methods: </strong>The search term and procedures were registered in PROSPERO (CRD42023391048). We systematically searched the databases PubMed/MEDLINE, CINAHL, PsycInfo, Web-of-Science Core Collection, Cochrane Library, adding a grey literature search. In addition to the narrative review, pooled effect sizes, moderation and subgroup analysis were calculated.</p><p><strong>Results: </strong>The systematic search yielded 1986 original reports of which 36 were included in the systematic review and 25 in the meta-analysis. Demoralization, help-/hopelessness, and self-efficacy were the most commonly studied facets of control, showing a relatively large, pooled correlation with suicidal ideation overall (r = 0.45, [95% CI = 0.38-0.52], Q = 346.15, p < 0.01, I² = 91.2%) and across operationalisations (demoralisation: r = 52; hopelessness: r = 45; self-efficacy: r = 0.40). Moderation analyses revealed no effect of cancer stages; but more directly cancer-associated variables (demoralisation, hopelessness) were more closely related to suicidal ideation (Q_M = 5.40, p = 0.02) than general self-efficacy.</p><p><strong>Conclusion: </strong>The findings underscore the pivotal role of perceived control in shaping severe distress in cancer patients. More studies are needed examining perceived control in a narrower sense.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 11","pages":"e70030"},"PeriodicalIF":3.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Mobile Application-Based Cognitive Behavioral Therapy on Psychological Outcomes in Women Treated for Breast Cancer: A Randomized Controlled Pilot Trial in Germany.","authors":"Ria Heinrich, Georgia Schilling, Ewa Wojtyna, Dirk Arnold, Mareike Geisler, Susanne Kley, Piotr Grudzinski, Małgorzata Księżak, Tonio Schoenfelder","doi":"10.1002/pon.70003","DOIUrl":"https://doi.org/10.1002/pon.70003","url":null,"abstract":"<p><strong>Objective: </strong>Breast cancer has a strong impact on the mental state of those affected. Cognitive behavioral therapy (CBT) is one effective approach to reduce disease burden. This randomized controlled pilot trial aimed to assess the effect of the digital CBT-based application Living Well on psychological outcomes in a German female breast cancer population.</p><p><strong>Methods: </strong>Female breast cancer patients (n = 70) with ongoing or finished oncological treatment that is who were receiving or had received any type of oncological treatment were included in the study and randomized to an intervention group (IG, n = 32) receiving Living Well in addition to care as usual, and a control group (CG, n = 38) receiving care as usual only. Participants completed standardized questionnaires at baseline and after 2, 4, 8, and 12 weeks to assess anxiety and depression (HADS) as primary outcomes, distress (DT), health-related quality of life (HRQoL, AQoL-8D), and illness perception (B-IPQ) as secondary outcomes.</p><p><strong>Results: </strong>After 12 weeks, significant (p < 0.05) higher improvements in the IG could be observed in anxiety levels, HRQoL, and illness perception, when compared to the CG. Age and time since diagnosis were found to be relevant covariates for anxiety levels. In distress levels, the IG showed a clinically relevant and nearly significant reduction compared to the CG (p = 0.057). No effects could be observed in depression levels.</p><p><strong>Conclusions: </strong>The results demonstrate the potential of Living Well to improve psychological outcomes of female breast cancer patients and encourage further studies evaluating the effectiveness of the digital application.</p><p><strong>Trial registration: </strong>The trial has been registered in the German Clinical Trials Register (DRKS00029918).</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"33 10","pages":"e70003"},"PeriodicalIF":3.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142506705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}