L Kelada, I Roziner, R Dahabre, G Bentley, P Poikonen-Saksela, K Mazzocco, B Sousa, R Pat-Horenczyk
{"title":"乳腺癌女性创伤后应激与创伤后成长的前瞻性多国研究：系列中介分析。","authors":"L Kelada, I Roziner, R Dahabre, G Bentley, P Poikonen-Saksela, K Mazzocco, B Sousa, R Pat-Horenczyk","doi":"10.1002/pon.70126","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Research suggests that posttraumatic stress symptoms (PTSS) after a breast cancer (BC) diagnosis may lead to posttraumatic growth (PTG). Further prospective research is needed to confirm this, and to examine whether modifiable factors mediate the relationship. This study aimed to prospectively determine whether PTSS predicts PTG, and whether social support and cognitive emotion regulation mediate the relationship between PTSS and PTG among women with BC.</p><p><strong>Methods: </strong>In this study, 489 women from four countries (Finland, Israel, Italy, Portugal) with BC completed questionnaires at diagnosis (M0), and 6-months (M6), 9-months (M9), 15-months (M15), and 18-months (M18) post-diagnosis. Questionnaires included the Posttraumatic Growth Inventory, PTSD Checklist for DSM-5, Cognitive Emotion Regulation Questionnaire, modified Medical Outcomes Study Social Support Survey, and sociodemographic questions. We used serial mediation to determine whether the relationship between PTSS (M6) and PTG (M18) was mediated by social support (M9) and positive cognitive emotion regulation (M15), controlling for age.</p><p><strong>Results: </strong>PTSS (M6) (B = 0.18, 95%CI = 0.07, 0.28), social support (M9) (B = 1.71, 95%CI = 0.30, 3.14) and positive cognitive emotion regulation (M15) (B = 3.34, 95%CI = 1.76, 4.92) all directly predicted PTG (M18). The serial mediation was significant with a very small effect size: PTSS negatively predicted social support which positively predicted positive cognitive emotion regulation which positively predicted PTG (effect = -0.013, 95%CI = -0.02, -0.005).</p><p><strong>Conclusions: </strong>Our study adds support for a prospective, positive relationship between PTSS and PTG among women with BC, and shows that this relationship may be mediated by social support and cognitive emotion regulation. Further research is needed to inform interventions to promote PTG.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 4","pages":"e70126"},"PeriodicalIF":3.3000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Prospective Multi-National Study of Posttraumatic Stress and Posttraumatic Growth Among Women With Breast Cancer: A Serial Mediation Analysis.\",\"authors\":\"L Kelada, I Roziner, R Dahabre, G Bentley, P Poikonen-Saksela, K Mazzocco, B Sousa, R Pat-Horenczyk\",\"doi\":\"10.1002/pon.70126\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>Research suggests that posttraumatic stress symptoms (PTSS) after a breast cancer (BC) diagnosis may lead to posttraumatic growth (PTG). Further prospective research is needed to confirm this, and to examine whether modifiable factors mediate the relationship. This study aimed to prospectively determine whether PTSS predicts PTG, and whether social support and cognitive emotion regulation mediate the relationship between PTSS and PTG among women with BC.</p><p><strong>Methods: </strong>In this study, 489 women from four countries (Finland, Israel, Italy, Portugal) with BC completed questionnaires at diagnosis (M0), and 6-months (M6), 9-months (M9), 15-months (M15), and 18-months (M18) post-diagnosis. Questionnaires included the Posttraumatic Growth Inventory, PTSD Checklist for DSM-5, Cognitive Emotion Regulation Questionnaire, modified Medical Outcomes Study Social Support Survey, and sociodemographic questions. We used serial mediation to determine whether the relationship between PTSS (M6) and PTG (M18) was mediated by social support (M9) and positive cognitive emotion regulation (M15), controlling for age.</p><p><strong>Results: </strong>PTSS (M6) (B = 0.18, 95%CI = 0.07, 0.28), social support (M9) (B = 1.71, 95%CI = 0.30, 3.14) and positive cognitive emotion regulation (M15) (B = 3.34, 95%CI = 1.76, 4.92) all directly predicted PTG (M18). The serial mediation was significant with a very small effect size: PTSS negatively predicted social support which positively predicted positive cognitive emotion regulation which positively predicted PTG (effect = -0.013, 95%CI = -0.02, -0.005).</p><p><strong>Conclusions: </strong>Our study adds support for a prospective, positive relationship between PTSS and PTG among women with BC, and shows that this relationship may be mediated by social support and cognitive emotion regulation. Further research is needed to inform interventions to promote PTG.</p>\",\"PeriodicalId\":20779,\"journal\":{\"name\":\"Psycho‐Oncology\",\"volume\":\"34 4\",\"pages\":\"e70126\"},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Psycho‐Oncology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1002/pon.70126\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Psycho‐Oncology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/pon.70126","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
A Prospective Multi-National Study of Posttraumatic Stress and Posttraumatic Growth Among Women With Breast Cancer: A Serial Mediation Analysis.
Objective: Research suggests that posttraumatic stress symptoms (PTSS) after a breast cancer (BC) diagnosis may lead to posttraumatic growth (PTG). Further prospective research is needed to confirm this, and to examine whether modifiable factors mediate the relationship. This study aimed to prospectively determine whether PTSS predicts PTG, and whether social support and cognitive emotion regulation mediate the relationship between PTSS and PTG among women with BC.
Methods: In this study, 489 women from four countries (Finland, Israel, Italy, Portugal) with BC completed questionnaires at diagnosis (M0), and 6-months (M6), 9-months (M9), 15-months (M15), and 18-months (M18) post-diagnosis. Questionnaires included the Posttraumatic Growth Inventory, PTSD Checklist for DSM-5, Cognitive Emotion Regulation Questionnaire, modified Medical Outcomes Study Social Support Survey, and sociodemographic questions. We used serial mediation to determine whether the relationship between PTSS (M6) and PTG (M18) was mediated by social support (M9) and positive cognitive emotion regulation (M15), controlling for age.
Results: PTSS (M6) (B = 0.18, 95%CI = 0.07, 0.28), social support (M9) (B = 1.71, 95%CI = 0.30, 3.14) and positive cognitive emotion regulation (M15) (B = 3.34, 95%CI = 1.76, 4.92) all directly predicted PTG (M18). The serial mediation was significant with a very small effect size: PTSS negatively predicted social support which positively predicted positive cognitive emotion regulation which positively predicted PTG (effect = -0.013, 95%CI = -0.02, -0.005).
Conclusions: Our study adds support for a prospective, positive relationship between PTSS and PTG among women with BC, and shows that this relationship may be mediated by social support and cognitive emotion regulation. Further research is needed to inform interventions to promote PTG.
期刊介绍：
Psycho-Oncology is concerned with the psychological, social, behavioral, and ethical aspects of cancer. This subspeciality addresses the two major psychological dimensions of cancer: the psychological responses of patients to cancer at all stages of the disease, and that of their families and caretakers; and the psychological, behavioral and social factors that may influence the disease process. Psycho-oncology is an area of multi-disciplinary interest and has boundaries with the major specialities in oncology: the clinical disciplines (surgery, medicine, pediatrics, radiotherapy), epidemiology, immunology, endocrinology, biology, pathology, bioethics, palliative care, rehabilitation medicine, clinical trials research and decision making, as well as psychiatry and psychology.
This international journal is published twelve times a year and will consider contributions to research of clinical and theoretical interest. Topics covered are wide-ranging and relate to the psychosocial aspects of cancer and AIDS-related tumors, including: epidemiology, quality of life, palliative and supportive care, psychiatry, psychology, sociology, social work, nursing and educational issues.
Special reviews are offered from time to time. There is a section reviewing recently published books. A society news section is available for the dissemination of information relating to meetings, conferences and other society-related topics. Summary proceedings of important national and international symposia falling within the aims of the journal are presented.
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