Psycho‐Oncology最新文献

{"title":"Scoping Review of Patient-Centered Outcomes in Gastrointestinal Cancer Care.","authors":"Anna Gombay, Joanna Yang, Luckshi Rajendran, Natalie Coburn, Alyson L Mahar, Amy Hsu, Claire Ludwig, Ekaterina Kosyachkova, Julie Deleemans, Ka Yan Ip, Luna Canaj, Regis Gu, Julie Hallet","doi":"10.1002/pon.70539","DOIUrl":"10.1002/pon.70539","url":null,"abstract":"<p><strong>Background: </strong>Patient-Centered Care (PCC)-that which addresses individual values, needs, and preferences-is a critical component of cancer care. Value-driven care requires evidence on outcomes that matter to patients, but Patient-Centered Outcomes (PCOs) are inconsistently defined and measured.</p><p><strong>Aims: </strong>This scoping review maps and charts the literature on PCOs in gastrointestinal (GI) cancer care and the measures used to assess them with the aim of facilitating a shift toward more PCC.</p><p><strong>Methods: </strong>We searched Medline, Embase, CINAHL, the Cochrane Library, and APA PsycINFO databases (2000-2025) to identify studies involving adult patients with GI cancers that reported or discussed at least one PCO, excluding survival. We summarized PCOs, measures used to assess them, and key study characteristics. Using qualitative cluster analyses, we then organized PCOs into a three-level hierarchy.</p><p><strong>Results: </strong>Of 1626 studies screened, 140 met inclusion criteria. Across these studies, we identified 187 PCOs and 286 measures. PCOs were grouped into six clusters: symptoms (27.4%), psychosocial (23.6%), lifestyle (23.1%), functional status (11.6%), care experience (8.5%), and healthcare utilization (5.8%). The most commonly mentioned PCO measures were three questionnaires: the EORTC QLQ-C30 (8.1%), FACT-G (4.2%), and the EQ-5D (2.5%).</p><p><strong>Conclusions: </strong>A wide range of PCOs and corresponding measures have been reported in GI cancer care research, with symptom, psychosocial, and lifestyle related PCOs being the most frequently studied. Considerable heterogeneity exists in both the PCOs reported and the measures used to assess them. Identifying PCOs that matter most to patients and standardizing their measurement will be essential to advancing PCC.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 8","pages":"e70539"},"PeriodicalIF":3.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13420803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148621248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Poetic Dignity Therapy Adaptation for Sexual and Gender Minority Patients With Cancer.","authors":"William E Rosa, Jaime L Gilliland, Courteney Rae Koo, Jenny Hegland, Harvey M Chochinov, Rachel A Hadler","doi":"10.1002/pon.70564","DOIUrl":"10.1002/pon.70564","url":null,"abstract":"<p><strong>Background: </strong>Sexual and gender minority (SGM) patients experience disproportionately poor psychosocial cancer outcomes when compared to non-SGM patients. Psychosocial interventions specifically tailored to this population are lacking.</p><p><strong>Aims: </strong>To assess feasibility, acceptability and preliminary efficacy of a modified Dignity Therapy (DT) intervention for sexual and gender minority (SGM) patients with cancer.</p><p><strong>Methods: </strong>We modified DT to incorporate questions about sexual and gender identity and a novel poetic interpretation of the dignity narrative (DT-SGM). The intervention was evaluated in a prospective pilot trial. SGM people with cancer diagnoses were recruited from a designated comprehensive cancer center. They participated in a single episode of DT-SGM, which was recorded and transcribed. The recording was used to generate a narrative and poem, which were reviewed with the patient. Feasibility was assessed by recruitment and completion rates; acceptability through questions in the DT Feedback Questionnaire and qualitative analyses of follow-up interviews.</p><p><strong>Results: </strong>45 individuals were screened and 27 approached; 13/27 (55.6%) completed the study. Participants were demographically mixed in terms of age, cancer diagnosis, sexual orientation, gender identity and race. All participants (13/13; 100%) found the intervention acceptable. Qualitative analysis revealed four themes regarding intervention acceptability: (1) timing and duration, (2) feeling connected, (3) DT as a helpful processing tool, and (4) meaningfulness of the experience. We identified 4 additional themes related to sexual and gender orientation, including: (1) charting one's own course, (2) finding meaning, (3) lack of acceptance/ discrimination, (4) love and belonging.</p><p><strong>Conclusions: </strong>DT-SGM is feasible and acceptable to SGM people with cancer.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 8","pages":"e70564"},"PeriodicalIF":3.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13449636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148685440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding Cancer Clinical Trial Participation in Rural Communities: A Qualitative Focus Group Study.","authors":"Yetunde Tagurum, Jennifer N Wells, Vickie Cater, Gigi A Gonzales, Kimberly J Kiplagat, Heidy Pickles, Sandra Baer, Kelli Mills, Crystal Clark, Stanley Jean-Charles, Lindsey Murkerson, Christina White, Lynn Bentz, Kim Vigal, Gustavo Fonseca, Chandni Patel, Bradley J Monk","doi":"10.1002/pon.70572","DOIUrl":"10.1002/pon.70572","url":null,"abstract":"<p><strong>Background: </strong>Participation in cancer clinical trials is essential for advancing oncologic care, yet enrollment among rural populations remains disproportionately low. These communities face many hurdles including geographical distance from medical centers, healthcare workforce shortages, and deep-seated medical mistrust that may contribute to survival inequities.</p><p><strong>Aims: </strong>To address these gaps, a Research Navigator program was launched through the Florida Cancer Specialists & Research Institute to engage rural Florida residents in focus group sessions to identify barriers to trial participation.</p><p><strong>Methods: </strong>Utilizing the Integrated Behavioral and Socioecological Framework (IBSF), the study conducted five semi-structured focus groups with 30 participants recruited from rural Florida counties. Participants included cancer survivors, advocates, caregivers, and those currently in treatment. Discussions centered on knowledge, experiences, perceived barriers, and willingness to participate in cancer clinical trials.</p><p><strong>Results: </strong>Although most participants expressed awareness of cancer clinical trials, focus group discussions revealed misconceptions regarding trial purpose, process, and accessibility. Across groups, commonly reported barriers to participation included limited access to reliable transportation, financial concerns, and mistrust of medical professionals and healthcare systems. Thematic analysis of focus group transcripts yielded four themes: (A) perception and lived experience, (B) trial information dissemination, (C) enrollment impediments, and (D) intervention strategies and implementation.</p><p><strong>Conclusion: </strong>In rural settings, decisions regarding cancer clinical trial participation are shaped by a complex interplay of trust, logistics, and information access. This study emphasizes the importance of viewing trials as routine care and suggests that navigator-led outreach and patient-centric technology are essential for creating equitable access.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 8","pages":"e70572"},"PeriodicalIF":3.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13453285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148700851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intimacy and Relationships Among Partnered Danes With and Without a History of Cancer: Findings From the Project SEXUS Cohort Study.","authors":"Cecilie H Madsen, Christian Graugaard, Susanne O Dalton, Mikael Andersson, Pernille E Bidstrup, Morten Frisch","doi":"10.1002/pon.70558","DOIUrl":"10.1002/pon.70558","url":null,"abstract":"<p><strong>Background: </strong>Intimacy and relationship dynamics are central to health and well-being and may buffer sexual difficulties in cancer survivors. Still, population-based evidence comparing intimacy, reasons for having sex, and relational aspects between cancer survivors and individuals without a history of cancer remains limited and inconsistent.</p><p><strong>Aim: </strong>To assess the perceived importance of various types of intimacy, frequent reasons for having sex, and relationship characteristics among partnered individuals with and without a history of cancer.</p><p><strong>Methods: </strong>We analyzed data from 47,718 partnered individuals from the nationally representative Project SEXUS cohort study, including 3177 cancer survivors and 44,541 individuals without a cancer history. Prevalence estimates were calculated for all measures, and logistic regression models were used to obtain demographically weighted, confounder-adjusted odds ratios with 95% confidence intervals for associations of cancer status with intimacy, sexuality, and relationship indicators, stratified by sex and time since diagnosis.</p><p><strong>Results: </strong>Cancer survivors reported importance of intimacy, frequent reasons for having sex, and relationship characteristics largely comparable to those reported by individuals without a history of cancer. Similar patterns were seen across sexes, both overall and within five years of diagnosis.</p><p><strong>Conclusion: </strong>Our findings indicate that, despite the well-established impact of cancer on sexual activity and functioning, not all aspects of sexual health are equally affected. In particular, the perceived importance of intimacy, reasons for engaging in sex, and relational characteristics appear largely unaffected by cancer. Together, these results underscore the importance of addressing sexual health holistically in survivorship care, encompassing resources embedded in intimacy and relationship dynamics.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 8","pages":"e70558"},"PeriodicalIF":3.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13501941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148809016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of a Physical Activity Intervention on Cognitive and Mental Health Outcomes in Cancer Survivors.","authors":"Kathryn E Chiang, Matt Masters, Scott Whalen, Sidney Donzella, Lauren C Bates-Fraser, Anita R Peoples, Charlie Zhong, Kristen Sullivan, Sheri J Hartman, Alpa V Patel, Erika Rees-Punia","doi":"10.1002/pon.70588","DOIUrl":"10.1002/pon.70588","url":null,"abstract":"<p><strong>Objective: </strong>Physical activity (PA) is a safe, effective non-pharmacological method for reducing many adverse symptoms among cancer survivors. However, evidence supporting the benefits of digital PA interventions on cognitive function, anxiety, and depression among survivors is inconsistent, with very few examining the fear of cancer recurrence (FCR). This trial with a cohort study aimed to examine the impact of a one-year digital PA intervention on changes in cognitive and mental health outcomes among cancer survivors.</p><p><strong>Methods: </strong>415 participants were randomized 2:1 to an interactive PA website or flexibility control website. Anxiety, depression, FCR, and perceived cognitive function measured at baseline and at three-, six-, and 12-month follow-ups were analyzed using linear mixed models adjusted for age. Two post-hoc analyses were performed: (1) stratified by compliance with website protocol and (2) excluding participants at baseline with low anxiety, depression, or FCR, or high cognitive functioning.</p><p><strong>Results: </strong>94% of participants included in this analysis were women (n = 368) with a mean age of 62 years (SD = 8.5). In intent-to-treat models, the intervention was not effective in improving depression, anxiety, cognitive function, or FCR; however, among participants with high baseline FCR, engaging with the PA website intervention led to a significant reduction in FCR throughout the trial duration (compliant: 19.2 [16.8-21.6] at month 12 compared to 23.8 [21.3-26.2] at baseline).</p><p><strong>Conclusions: </strong>Overall, the intervention showed no meaningful effects on depression, anxiety, or perceived cognitive function. Post-hoc findings suggested reduced FCR among compliant survivors with elevated baseline FCR, warranting prospective validation.</p><p><strong>Trial registration: </strong>This trial was registered on ClinicalTrials.gov (NCT05356988).</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 8","pages":"e70588"},"PeriodicalIF":3.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13505528/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148814053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurotrophic-Inflammatory Imbalance and Cognitive Decline After Adjuvant Chemotherapy in Colon Cancer: A Prospective Cohort Study.","authors":"Zeynep Gülsüm Güç, Leyla Demir, Hüseyin Döngelli, İbrahim Bilen, Mert Uge, Mehmet Eren Kalender, Ahmet Alacacıoğlu, Mustafa Oktay Tarhan","doi":"10.1002/pon.70590","DOIUrl":"10.1002/pon.70590","url":null,"abstract":"<p><strong>Background: </strong>Cancer-related cognitive impairment (CRCI) is a prevalent yet underrecognized complication among colon cancer survivors that adversely affects quality of life and psychological well-being. Emerging evidence suggests that neurotrophic dysregulation and systemic inflammation may contribute to chemotherapy-related neurotoxicity; however, longitudinal biomarker-based data remain limited.</p><p><strong>Methods: </strong>In this prospective cohort study, 127 patients with resected colon cancer were evaluated at baseline and at the 6-month follow-up. Of these, 83 received adjuvant chemotherapy and 44 underwent postoperative surveillance alone. Cognitive performance (MoCA), depressive symptoms (HADS-D), and peripheral neuropathy (CIPN20) were assessed alongside serum brain-derived neurotrophic factor (BDNF) levels and systemic inflammatory markers, including neutrophil-to-lymphocyte ratio (NLR) and C-reactive protein-to-albumin ratio (CAR). Linear mixed model and logistic regression analyses were performed to identify factors associated with cognitive decline.</p><p><strong>Results: </strong>Adjuvant chemotherapy was associated with significant reductions in MoCA scores and serum BDNF levels (both p < 0.001), particularly among patients receiving the oxaliplatin-based XELOX regimen. Greater longitudinal reductions in BDNF (ΔBDNF) were independently associated with higher odds of CRCI (OR = 0.749 per 10 ng/mL increase in ΔBDNF, 95% CI: 0.658-0.854, p < 0.001). The model including ΔBDNF showed higher apparent discrimination than the corresponding model without ΔBDNF (AUC = 0.929 vs. 0.812).</p><p><strong>Conclusion: </strong>Longitudinal reductions in serum BDNF were independently associated with CRCI among patients receiving adjuvant chemotherapy. These findings support a potential role for neurotrophic dysregulation in chemotherapy-related cognitive decline and highlight the need for further validation studies evaluating BDNF as a candidate biomarker for CRCI.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 8","pages":"e70590"},"PeriodicalIF":3.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13505728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148819116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thinking, Feeling, Choosing: How Affect Is Reflected in Prostate Cancer Treatment Decision Making-A Qualitative Study.","authors":"Rui Gong, Nayrelis Alfonso, Aida M van Mossel, Maria Nieto Ordosgoitia, Jacqueline M Montano, Armand Jacques, Lara Traeger, Aaron S Heller, Michael H Antoni, Tracy E Crane, Mark L Gonzalgo, Brandon A Mahal, Bruno Nahar, Chad Ritch, Dipen J Parekh, Sanoj Punnen, Frank J Penedo","doi":"10.1002/pon.70569","DOIUrl":"10.1002/pon.70569","url":null,"abstract":"<p><strong>Background: </strong>Shared decision-making (SDM) emphasizes informed, value-aligned choices, yet affect has not been a primary focus and is rarely addressed explicitly in cancer contexts. Among men with low-to intermediate-risk prostate cancer (LIRPC), active treatment and active surveillance each involve distinct affective challenges that may influence risk perception, decisional uncertainty, and treatment satisfaction. Despite prior work in affect and decision making literature, its integration into cancer contexts remains limited.</p><p><strong>Aims: </strong>To address the gap, this study examined how affect, alongside cognition and psychosocial factors, was reflected in men's accounts of LIRPC treatment decision making, guided by SDM and affective science frameworks.</p><p><strong>Methods: </strong>We conducted semi-structured interviews with 28 men with LIRPC across three treatment pathways: AS, AT, and AS-AT transition. Interviews were theory-informed and explored (a) how participants learned and interpreted diagnostic information; (b) how thoughts, emotions, and relationships were experienced in decision-making; and (c) how men reflected on preferred roles. Participants also completed the Control Preferences Scale.</p><p><strong>Results: </strong>Eleven themes emerged across domains. Understanding of information depended on both the clarity of medical communication and its relational context. Participants described strong affective responses at diagnosis, awaiting test results, and shortly before surgery. Decision-making was often deliberative, with men weighing options alongside personal values and priorities, physician trust, and family support. Post-treatment reflections emphasized autonomy and value alignment, with coping used to manage affect and maintain a sense of control.</p><p><strong>Conclusions: </strong>In LIRPC decision-making, affect appeared to vary across contexts and time points. Although decisions were often described as deliberative, affect seemed embedded in how men interpreted information, navigated relationships, and defined what mattered (including quality of life, anticipated treatment outcomes, and autonomy), which influenced how options were weighed. Incorporating affect into decision support, particularly around key moments, may strengthen SDM and treatment satisfaction.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 8","pages":"e70569"},"PeriodicalIF":3.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13453287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148702239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dyadic Latent Profiles of Sexual and Reproductive Distress in Young Adult Cancer Survivors and Their Partners: A Cross-Sectional Analysis.","authors":"Jessica R Gorman, Soyoung Choun, Karen S Lyons, Chiara Acquati, S Marie Harvey, John M Salsman, Lisa Flexner, Geethika Koneru, Brandon Hayes-Lattin, Jennifer B Reese","doi":"10.1002/pon.70587","DOIUrl":"10.1002/pon.70587","url":null,"abstract":"<p><strong>Background: </strong>Young adult (YA) breast and gynecologic cancer (BGC) survivors commonly experience sexual and reproductive health (SRH) distress after cancer, with far-reaching consequences for relational functioning, health outcomes, and quality of life. Despite this burden, the dyadic experience and relational patterns of SRH distress in this population have not been well characterized.</p><p><strong>Aims: </strong>The objectives of this study were to characterize dyadic profiles of SRH distress and to examine the association with other individual and interpersonal characteristics.</p><p><strong>Methods: </strong>This study employed dyadic Latent Profile Analysis (LPA) in STATA/SE to identify distinct SRH distress profiles across 79 survivor-partner couples, with measures of reproductive and sexual distress as LPA indicators. Following profile identification, we used ANOVA and chi-square tests to examine how these dyadic profiles differed across characteristics.</p><p><strong>Results: </strong>Three dyadic profiles emerged: low-distress (30.4%), moderate-distress (43.0%), and high-distress (26.6%). Low-distress couples had significantly higher levels of dyadic coping, constructive communication, and open discussion of SRH concerns along with the highest rates of sexual activity. In contrast, high-distress couples demonstrated poorer coping and communication and significantly lower sexual activity. Moderate-distress dyads fell between these extremes. Comparisons across these profiles showed no significant differences in demographic or cancer characteristics.</p><p><strong>Conclusions: </strong>Findings underscore the central role of relationship processes, including dyadic coping and communication, and their potential as modifiable intervention targets for YA BGC survivor couples experiencing SRH distress. Identifying distinct couples' profiles of SRH distress may facilitate more precise identification of high-need dyads and guide the development of tailored interventions.</p><p><strong>Trial registration: </strong>NCT04806724.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 8","pages":"e70587"},"PeriodicalIF":3.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13502115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148809102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of a Stepped-Care Approach to Cognitive-Behavioural Therapy for Insomnia (Can-Sleep) in Adolescents and Young Adults With Cancer.","authors":"Jordan Maccora, Maria Ftanou, Emma Vaughan, Andrew Murnane, Jeremy Lewin, Ilana Berger, Joshua F Wiley, Michael Jefford, Martha Hickey, Jeremy Goldin, Kate Thompson","doi":"10.1002/pon.70549","DOIUrl":"10.1002/pon.70549","url":null,"abstract":"<p><strong>Objective: </strong>Poor sleep is a common issue among adolescents and young adults (AYA) with cancer. The present study describes the feasibility and impact of the Can-Sleep stepped-care intervention for AYA with cancer.</p><p><strong>Methods: </strong>A total of 51 AYA with cancer were screened. AYA who reported sleep disturbance (defined as insomnia severity index score [ISI] > 7) received self-managed cognitive behavioural therapy for insomnia (SMCBT-I) in the first instance (Step 1) followed by individual cognitive behavioural therapy for insomnia (ICBT-I) if symptoms continued (Step 2). AYA screened as high risk for intrinsic sleep abnormalities (e.g., obstructive sleep apnoea) were referred to a specialised service.</p><p><strong>Results: </strong>Of the 51 AYA, 38 participants reported sleep disturbance. In total, 37 AYA commenced SMCBT-I, four attending the specialised sleep service prior. Thirty-one (84%) completed Step 1. Of these, 45% improved and required no further treatment, and 55% (17) were eligible for ICBT-I (ISI > 7). Following intervention, the SMCBT-I group showed a significant decline in insomnia symptoms (p < 0.001, d = 0.84). Among the 17 AYA continuing to report sleep disturbance, 11 (65%) were referred to ICBT-I, with 8 (73%) accepting and completing Step 2. Those who received the ICBT-I showed a significant reduction in insomnia symptoms (p = 0.007, d = 1.33).</p><p><strong>Conclusions: </strong>This study provides preliminary efficacy and acceptability of a stepped-care intervention for sleep disturbances in AYA with cancer. A stepped-care intervention may offer an effective and resource-efficient method for managing sleep disturbance in AYA with cancer.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 8","pages":"e70549"},"PeriodicalIF":3.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13445639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148679818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating the Psychosocial Journey: A Meta-Ethnographic Review of the Psychosocial Needs and Experiences of Children and Adolescents (0-19 Years) Diagnosed With Cancer Across the Care Continuum.","authors":"Alyssa Ebert, Carolyn Ee, Oluwaseyifunmi Andi Agbejule, Michael Osborn, Murray Turner, Catherine Paterson","doi":"10.1002/pon.70582","DOIUrl":"https://doi.org/10.1002/pon.70582","url":null,"abstract":"<p><strong>Background: </strong>Survival rates for childhood cancer have improved; however, psychosocial challenges remain across diagnosis, treatment, and survivorship. Existing qualitative studies typically examine a single phase of care, limiting understanding of how psychosocial needs persist and change over time.</p><p><strong>Aim: </strong>This meta-ethnographic review synthesised qualitative evidence on the psychosocial needs and experiences of children and adolescents (0-19 years) diagnosed with cancer across the care continuum and examined how these needs evolve across phases.</p><p><strong>Method: </strong>A meta-ethnographic synthesis was conducted following Noblit and Hare's approach and reported in accordance with eMERGe guidance. Searches of six databases (Scopus, MEDLINE, Web of Science, PsycINFO, CINAHL, and Google Scholar) identified 31 qualitative studies published between January 2009 and February 2025. First- and second-order constructs were extracted, coded by age group and continuum phase, and integrated into a line-of-argument synthesis.</p><p><strong>Results: </strong>Six psychosocial domains consistently shaped children's needs and experiences: family, relationships, psychosocial care, emotions, control, and information needs. These domains remained consistent across diagnosis, treatment, and survivorship but differed in expression over time. Diagnosis was characterised by emotional shock, uncertainty, and reliance on parental containment. During treatment, children experienced procedural distress, disrupted peer relationships, and fluctuating autonomy. Survivorship involved fear of relapse, challenges with reintegration, and inconsistent psychosocial follow-up. Evidence gaps were identified for toddlers' and school-aged children's needs in survivorship.</p><p><strong>Conclusion: </strong>This synthesis highlights the prehabilitation phase as a potential window for early psychosocial intervention and supports the development of phase-responsive, developmentally responsive psychosocial care pathways extending into survivorship.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"35 8","pages":"e70582"},"PeriodicalIF":3.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13484188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148797431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}