Psycho‐Oncology最新文献

{"title":"Study of Uprooting in Pediatric Cancer Care for Children From the French West Indies and Guiana Treated in Mainland France: A Qualitative Study.","authors":"Chloe Vanlaer, Claire Dichamp, Narcisse Elenga, Frederique Delion, Graziella Raimondo, Sylvie Fasola, Sandrine Haghiri, Katell Michaux, Yves Hatchuel, Benjamin Faivre, Etienne Seigneur, Marie Simbozel, Quentin Neven, Céline Khouri, Arthur Felix, Anais Ogrizek","doi":"10.1002/pon.70242","DOIUrl":"10.1002/pon.70242","url":null,"abstract":"<p><strong>Background: </strong>A diagnosis of childhood cancer has a profound impact on families, especially when treatment requires relocation. Children from the French West Indies (FWI) and French Guiana (FG) are often treated in specialized centers in mainland France, resulting in physical and cultural uprooting that poses unique psychosocial challenges.</p><p><strong>Aims: </strong>This study explores the impact of uprooting on the dynamics and well-being of these families.</p><p><strong>Methods: </strong>This qualitative observational study used semi-structured interviews with parents of pediatric cancer patients from the FWI and FG. Eligible participants were French-speaking primary caregivers with parental authority who accompanied their children for treatment in mainland France. Interviews were conducted between November 2023 and February 2024, recorded, transcribed, and analyzed using Interpretative Phenomenological Analysis with NVivo software.</p><p><strong>Results: </strong>Among the 10 families interviewed, uprooting significantly disrupted family dynamics and required complex adjustments. Parents reported challenges in accessing resources to manage the stress of their child's diagnosis and treatment, but expressed overall satisfaction with the healthcare received. Psychological support was essential, with many finding comfort in religious practices. Financial and social difficulties were common. Children generally adapted better than expected but struggled with separation from their familiar environment, while siblings often felt abandoned.</p><p><strong>Conclusion: </strong>This study is the first to examine the impact of uprooting on childhood cancer treatment for families from this region. Providing care closer to home may reduce psychological and financial burdens. Recommendations include establishing regional pediatric oncology units and increased support from social services. Future research should focus on non-accompanying parents, siblings, and schooling to understand the long-term effects on survivors and develop targeted psychological and social interventions.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 8","pages":"e70242"},"PeriodicalIF":3.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12306847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144744541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brief Post-Surgical Stress Management Intervention Effects on Positive Psychological Well-Being and Self-Efficacy in Women Being Treated With Adjuvant Endocrine Therapy for Hormone-Receptor Positive Breast Cancer.","authors":"Molly Ream, Chloe J Taub, Hermioni L Amonoo, Emily A Walsh, Paula Popok, Rachel Plotke, Jamie M Jacobs, Lisa M Gudenkauf, Frank J Penedo, Daniel O'Neil, Gail Ironson, Steven A Safren, Michael H Antoni","doi":"10.1002/pon.70267","DOIUrl":"https://doi.org/10.1002/pon.70267","url":null,"abstract":"<p><strong>Background: </strong>Women prescribed adjuvant endocrine therapy (AET) for nonmetastatic breast cancer may experience a decline in positive psychological well-being (PPWB) and self-efficacy. Brief cognitive behavioral therapy (CBT) and relaxation training (RT) interventions have shown short-term efficacy in reducing distress, but their impact on PPWB and self-efficacy over longer periods among women prescribed AET is unknown.</p><p><strong>Aims: </strong>We aimed to investigate longitudinal effects of CBT and RT on PPWB and self-efficacy among women prescribed AET.</p><p><strong>Methods: </strong>This secondary analysis of a randomized controlled trial comparing 5-session CBT versus RT versus a time-matched health education (HE) control for women with nonmetastatic breast cancer examined PPWB (positive affect, benefit finding, positive states of mind, optimism), coping self-efficacy, and relaxation self-efficacy at four timepoints over the first-year post-diagnosis and at median 8-year follow-up. Piecewise hierarchical linear modeling tested intervention effects on longitudinal trajectories among women prescribed AET from the parent study (N = 135).</p><p><strong>Results: </strong>Over the first-year post-surgery, positive affect and relaxation self-efficacy increased across all conditions (ps < 0.03). Women in CBT reported enhanced positive states of mind compared to those in HE (p = 0.044) and enhanced coping self-efficacy versus those in RT (p = 0.029). Women in HE reported enhanced coping self-efficacy versus those in RT (p = 0.043). All intervention effects persisted at 8-year follow-up. There were no significant effects on optimism or benefit finding.</p><p><strong>Conclusions: </strong>Brief interventions may bolster aspects of PPWB and self-efficacy in women prescribed AET. Testing is warranted to determine whether more PPWB components can be incorporated into these interventions to further enhance outcomes.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 8","pages":"e70267"},"PeriodicalIF":3.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12373568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-Utility Analysis of a Group Mindfulness Program Compared to an Education Support Program for Breast Cancer Survivors With Cognitive Impairment: Evidence From a Randomized Controlled Trial.","authors":"Hongdao Meng, Cecile A Lengacher, Rio Tate, Carmen Rodríguez, Kevin E Kip, Jong Y Park, Gizem Hueluer, Anh Thy Nguyen, Sandra Morgan, Sara Tinsley, Britney Veal, Anisha Joshi, Mahathi Krothapalli, Sreenidhi Nidamanur, Charles Cox, Lynne S Padgett, Manolete Moscoso, Elizabeth Bornstein, Jean M Lucas, Tamela Fonseca, Kristine A Donovan, Ramya Chamkeri, Richard R Reich","doi":"10.1002/pon.70220","DOIUrl":"10.1002/pon.70220","url":null,"abstract":"<p><strong>Objective: </strong>To conduct an economic evaluation of a group mindfulness program compared to an education support program for breast cancer survivors (BCS).</p><p><strong>Methods: </strong>The cost-utility analysis (cost per quality-adjusted life year [QALY]) was performed from a single-center randomized controlled trial in the United States. Data from 181 BCS were included in the analysis (91 from the mindfulness-based stress reduction for breast cancer, MBSR(BC) and 90 from the Breast Cancer Education Support, (BCES)). Analyses were conducted from two perspectives: societal and healthcare system. The EuroQol EQ-5D-5L was used to measure quality of life and the Client Service Receipt Inventory (CSRI) was used to measure health services utilization from baseline through 26 weeks. The impact of MBSR(BC) on health services utilization and costs was estimated with generalized linear models.</p><p><strong>Results: </strong>In the reference case analyses (societal perspective), the average total cost in the MBSR(BC) group was $5744 compared with $6140 in the BCES group. At the end of follow-up, the MBSR(BC) group dominated BCES in terms of Incremental Cost Utility Ratio (ICUR), with MBSR(BC) providing an incremental cost of -$541 (95% CI: -$3400, $2318) and a 0.021 QALY (95% CI: -0.014, 0.055). Net monetary benefit (NMB) analysis showed that MBSR(BC) has a higher probability of achieving positive NMB across a range of possible societal willingness-to-pay for improving quality of life.</p><p><strong>Conclusions: </strong>Our findings suggest that MBSR(BC) is likely to be cost-effective for breast cancer survivors over 6 months. Cost savings primarily resulted from reduced ER and hospital admissions and tests.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 7","pages":"e70220"},"PeriodicalIF":3.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144691297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Communication Between Japanese Patients With Hereditary Breast and Ovarian Cancer and Healthcare Providers on Sexual Health After Risk-Reducing Bilateral Salpingo-Oophorectomy.","authors":"Manami Matsukawa, Eri Habano, Masako Torishima, Makiko Dazai, Makoto Hirata, Shinji Kosugi","doi":"10.1002/pon.70212","DOIUrl":"10.1002/pon.70212","url":null,"abstract":"<p><strong>Background: </strong>Risk-reducing bilateral salpingo-oophorectomy (RRBSO) is recommended for BRCA1/2 carriers to reduce ovarian cancer risk. Although RRBSO affects sex life, discussing this with healthcare professionals (HCPs) can be challenging. Moreover, research on this topic in Asia is limited.</p><p><strong>Aims: </strong>This study aims to clarify HCPs' communication on RRBSO's impact on sex life and to consider the preferred communication methods of Japanese BRCA1/2 carriers and their partners.</p><p><strong>Methods: </strong>A web survey was conducted with BRCA1/2 carriers and their partners using snowball sampling. Participants who agreed to the additional interview underwent interviews. Thematic analysis was performed on free-text responses and interview data. A pamphlet reflecting experiences with RRBSO was published after the survey, and feedback was obtained online.</p><p><strong>Results: </strong>Of the 50 surveyed participants, 10 underwent interviews. Three themes emerged: (1) hesitancy to ask questions about sex life, (2) the need to inform and support couples on their sex life after RRBSO, and (3) the unhelpfulness of receiving explanations from those who have not undergone RRBSO. Only 34.0% of participants received information on post-RRBSO sex life. Many expressed the need for themselves and their partners to receive information before RRBSO. The feedback survey revealed that digital pamphlets and paper were the preferred tools.</p><p><strong>Conclusions: </strong>Providing couples with information about post-RRBSO sex life is essential. Additionally, cultural taboos hinder discussions on sex life leading to a preference for indirect sources of information. In Japan, some patients may face challenges in directly communicating with HCPs, highlighting the value of pamphlets and digital resources.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 7","pages":"e70212"},"PeriodicalIF":3.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the Unspoken: Exploring Taboo Thoughts and Difficult Experiences Among Carers of People With Brain Cancer.","authors":"Emma McDougall, Sara Nordentoft, Sine Kjærgaard, Georgia K B Halkett, Anna K Nowak, Haryana M Dhillon, Lauren J Breen, Karin Piil","doi":"10.1002/pon.70231","DOIUrl":"10.1002/pon.70231","url":null,"abstract":"<p><strong>Objective: </strong>The primary objective of this research was to explore the rarely discussed, often unspoken, taboo thoughts and difficult emotions experienced by carers who support individuals with brain tumour related personality and behaviour changes. A secondary aim of this study was to examine coping strategies used by these carers.</p><p><strong>Methods: </strong>A qualitative interview study was conducted with participants from Australia (n = 7) and Denmark (n = 6) (92% female, aged 42-68 years) who had been or were current carers for someone with a primary malignant brain tumour who was displaying personality changes. Semi-structured interviews were conducted. Using thematic analysis, key themes were identified.</p><p><strong>Results: </strong>Four key themes related to carers' unspoken thoughts were identified: (1) Staying safe: \"His aggression was just out of this world\"; (2) Conflicting and complex emotions: \"I love him for who he was\"; (3) Wishing for the end with grief and relief and (4) Experiences of patient death and end of life treatment decisions. Carers described five coping strategies: (1) Commitment to care; (2) Life alongside carer role; (3) Acceptance of circumstances; (4) Self-silencing; and (5) Information seeking and safety planning.</p><p><strong>Conclusions: </strong>The relentless nature of this disease and potential treatment side effects places an immense burden on carers that often is unspoken. The findings highlight the importance of healthcare professionals providing support for carers, in asking about their experience, and appropriate assessment and management of brain tumour related aggression. The results hold the potential to inform targeted interventions for the unique challenges faced by carers supporting someone with brain tumour related personality and behaviour changes.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 7","pages":"e70231"},"PeriodicalIF":3.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12267670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suicide Ideation, Attempt and Mortality in Childhood Cancer Survivors a Scoping Review of the Literature.","authors":"Eva De Clercq, Simone Nadine Föhn, Gisela Michel","doi":"10.1002/pon.70197","DOIUrl":"10.1002/pon.70197","url":null,"abstract":"<p><strong>Objectives: </strong>Despite improved long-term prognosis, childhood cancer survivors often experience many long-term complications, which severely affect their quality of life. The aim of this scoping review is to summarize empirical evidence on suicidal ideation, attempt and mortality in childhood cancer survivors in order to contribute to the further development of survivorship follow-up care.</p><p><strong>Methods: </strong>Six databases were systematically searched (PubMed, Scopus, Cochrane library, CINAHL, PsycINFO and Embase). Included studies were published in peer-reviewed journals, used quantitative or mixed research methods. The review was conducted and reported by adhering to the guidelines of the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews.</p><p><strong>Results: </strong>Although there were important differences in the reported prevalence of suicidality (i.e. ideation, attempt and mortality) in the retrieved literature, overall the risk of suicide mortality (0.1%-1.6%) among childhood cancer survivors seems low. The risk of suicide attempt ranged between 0.44% and 3.3%. The overall risk of suicidal ideation appears to be relatively common (4.3%-17%). Across studies, there were numerous inconsistencies regarding the impact of specific risk factors on suicidality. Included studies often did not report on the identification of protective factors or on the development of population specific preventative interventions.</p><p><strong>Conclusion: </strong>Suicidal ideation is a profound form of emotional and psychological distress, and therefore an important quality of life issue for survivors and their families. Universal screening by suicide specific screens throughout the continuum of survivorship should be the recommended approach in the absence of clear risk factors that identify which childhood cancer survivors are the most vulnerable to suicidality.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 7","pages":"e70197"},"PeriodicalIF":3.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12241763/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychosocial and NF-κB Activity Effects of the Stress Management and Resiliency Training: Relaxation Response Resiliency Program (SMART-3RP) on Patients With MGUS and Smoldering Multiple Myeloma: A Randomized Waitlist Control Trial.","authors":"Lucy Finkelstein-Fox, John W Denninger, Leah E Walsh, Jacob P Laubach, Andrew Jenho Yee, Elizabeth O'Donnell, Eric A Macklin, Xuesong Gu, Alona Muzikansky, Towia A Libermann, Gabriella Nicolosi, Paul G Richardson, Noopur S Raje, Gregory L Fricchione, Giselle K Perez, Lara N Traeger, Emma Chad-Friedman, Elyse R Park","doi":"10.1002/pon.70216","DOIUrl":"10.1002/pon.70216","url":null,"abstract":"<p><strong>Background: </strong>Patients with monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM), precursors to multiple myeloma, need supports for the psychological sequelae of medical uncertainty.</p><p><strong>Aims: </strong>This secondary and exploratory analysis of psychosocial outcomes from a randomized controlled trial evaluated a mind-body intervention, the Stress Management and Resiliency Training: Relaxation Response Resiliency Program (SMART-3RP) for perceived stress, global distress and secondary distress (depression, anxiety, NF-κB DNA-binding activity) and well-being (coping ability, mindfulness, optimism, gratitude) indices for individuals with MGUS and SMM.</p><p><strong>Methods: </strong>Participants were randomized to immediate treatment (n = 45) or waitlist control (n = 48), providing data at baseline (T1), 3 months (T2), and 6 months (T3).</p><p><strong>Results: </strong>Compared to waitlist control, the immediate treatment group experienced greater T1-T2 reductions in global distress (M_diff = -1.04, p = 0.04), but not perceived stress (M_diff = -1.67, p = 0.12). Participants receiving immediate treatment also experienced greater reductions in depression (M_diff = -4.22, p < 0.001) and improvements in coping abilities (M_diff = 0.36, p < 0.001) and optimism (M_diff = 1.39, p = 0.02), with no significantly different changes in mindfulness (M_diff = 4.36, p = 0.14), anxiety (M_diff = -1.23, p = 0.26), gratitude (M_diff = 0.59, p = 0.47), or NF-κB activity (M_diff = -0.16, p = 0.23).</p><p><strong>Conclusions: </strong>The SMART-3RP demonstrated efficacy for global distress and other important outcomes for individuals with MGUS and SMM. Stress reduction did not significantly differ from waitlist control.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov Registration #: NCT01955395.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 7","pages":"e70216"},"PeriodicalIF":3.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Network Analysis of Anxiety in Prostate Cancer Patients.","authors":"Christopher F Sharpley, Rebecca J Williams, Vicki Bitsika, Wayne M Arnold, David R H Christie","doi":"10.1002/pon.70237","DOIUrl":"10.1002/pon.70237","url":null,"abstract":"<p><strong>Background: </strong>A large proportion of prostate cancer (PCa) patients also report being anxious, which can impede their recovery and adversely influence their personal relationships.</p><p><strong>Aims: </strong>In order to better understand the relationships between symptoms of anxiety in these men, with a view towards more informed treatments for anxiety, the network structure of the symptomatology for Generalised Anxiety Disorder (GAD) was examined in this study.</p><p><strong>Methods: </strong>A total of 425 PCa patients completed the GAD-7 and an extended version of that inventory (the GAD-10). Data were analysed via Network Analysis, Pearson correlation coefficients, and ANOVA.</p><p><strong>Results: </strong>Network analysis and multidimensional scaling indicated that being unable to control worry was the most central symptom for these men, and that several sets of GAD symptoms were closely associated with each other. These included worrying, inability to relax, and restlessness. Other anxiety symptoms such as sleeping problems, difficulty concentrating, and feeling tyred were less well-related with the remainder of the network. Implications for clinical practice were derived from the relationships between individual anxiety symptoms and the overall anxiety network by examining node predictability, and focused upon helping these men to 'switch off' from their worry by engaging in mutually-incompatible behaviours.</p><p><strong>Conclusions: </strong>The use of total anxiety inventory scores fails to identify the underlying network structure of anxiety in PCa patients. By finding the central GAD symptom of being unable to control their worry, more individually-focussed anti-anxiety treatments might be developed and offered to these men.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 7","pages":"e70237"},"PeriodicalIF":3.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12274292/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Family Resilience in Adolescent and Young Adult Patients With Hematological Malignancies: A Qualitative Study of Patients and Family Caregivers.","authors":"Yiwen Zhang, Li Wang, Rui Cao, Lu Chen, Hongyan Yuan, Ruiye Li, Xiuping Jiang, Yanmei Cheng, Huijing Zou, Bing Xiang Yang, Qian Liu","doi":"10.1002/pon.70224","DOIUrl":"https://doi.org/10.1002/pon.70224","url":null,"abstract":"<p><strong>Objective: </strong>Family resilience plays a vital role in coping with cancer. However, little research has explored how adolescents and young adults (AYAs) with hematological malignancies and their families adapt to cancer, particularly during this critical developmental stage.</p><p><strong>Aims: </strong>This study aims to explore how AYAs with hematological malignancies and their families experience the dynamic process of family resilience.</p><p><strong>Methods: </strong>Using a descriptive phenomenological approach, semi-structured interviews were conducted with 40 participants from 26 families, including 19 AYAs with hematological malignancies and 21 family caregivers. Data were collected between April 2023 and March 2025 at two general hospitals in central China. Interviews were analyzed using Colaizzi's method.</p><p><strong>Results: </strong>Four themes and 11 subthemes emerged. Theme 1: challenges faced by families: (a) multiple challenges for patients, (b) intense family caregiver burden, and (c) shared fear of relapse and uncertainty. Theme 2: internal adaptation within families: (a) flexible role and responsibility adjustment, (b) fostering shared decision-making and autonomy through communication, and (c) emotional suppression and coping strategies. Theme 3: external social support and resources: (a) received social support, and (b) limitations in the social support system. Theme 4: self-transcendence and growth: (a) personal growth, (b) gratitude toward family and society, and (c) maintaining hope and adjusting plans.</p><p><strong>Conclusions: </strong>This study reveals that family resilience among AYAs with hematological malignancies is a dynamic and cyclical process shaped by continuous adaptation to evolving challenges. While family resilience supports personal growth, families remain under ongoing stress. These findings highlight the need for culturally sensitive and developmentally tailored interventions to better support both patients and caregivers throughout the illness trajectory.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 7","pages":"e70224"},"PeriodicalIF":3.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144619931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility Randomised Controlled Trial of a New Digital Intervention ('FRAME') to Promote Resilience in Women Treated for Primary Breast Cancer.","authors":"Anna V Cartwright, Hannah Krzyzanowski, Rona Moss-Morris, Laura Smith, Yogini Sawjani, Camilla Böhme Kristensen, Nuvera Mukaty, Sam Norton, Jo Armes, Colette R Hirsch","doi":"10.1002/pon.70217","DOIUrl":"10.1002/pon.70217","url":null,"abstract":"<p><strong>Objective: </strong>This study investigates the acceptability of a novel Cognitive Bias Modification for Interpretation (CBM-I) intervention, 'FRAME', to promote resilience in women who have completed active treatment for primary breast cancer and determines the feasibility of a full-scale randomised controlled trial.</p><p><strong>Methods: </strong>A two-armed, participant-blind, parallel groups randomised controlled trial of CBM-I versus a time-matched control. Participants were recruited from community organisations and social media. Measures of acceptability, feasibility, change in interpretation bias and clinical outcomes (resilience, mood and quality of life) were assessed at baseline (T0), 1-month post-randomisation (T1, end of intervention), 2-month (T2) and 4-month post-randomisation (T3).</p><p><strong>Results: </strong>Sixty-seven participants completed baseline assessment and were randomised to the FRAME CBM-I (n = 35) or control group (n = 32). Acceptability of CBM-I met pre-specified progression criteria, and 80% adhered to the CBM-I intervention. Between-group differences in interpretation bias at T1 demonstrated a moderate effect in favour of CBM-I on two measures of interpretation bias (SMD_g = 0.66 and 0.73). Effect size estimates suggest moderate treatment effects on resilience (SMD_g = 0.64) and small effects on mood, in favour of FRAME. No intervention-related adverse events were reported.</p><p><strong>Conclusions: </strong>The study results provide strong support for the acceptability of a new online CBM-I intervention ('FRAME') to promote resilience in women treated for primary breast cancer and indicate that a full-scale trial is feasible. The study fulfiled all pre-specified progression criteria to advance to an efficacy trial, except meeting the recruitment target of 70 participants. Importantly, recruitment took place during the Covid-19 pandemic. Recommendations for future research are provided.</p>","PeriodicalId":20779,"journal":{"name":"Psycho‐Oncology","volume":"34 7","pages":"e70217"},"PeriodicalIF":3.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}