Quality of Life Research最新文献

{"title":"Informal carers' perception on perspective taking when reporting as proxies about someone else's health.","authors":"Henok Dagne, Kathleen Doherty, Alice Saul, Julie Campbell, Ingrid van der Mei, Bruce V Taylor, Jessica Roydhouse","doi":"10.1007/s11136-026-04375-w","DOIUrl":"10.1007/s11136-026-04375-w","url":null,"abstract":"<p><strong>Purpose: </strong>Informal carers ('proxies') are often asked to report on the health of individuals who cannot self-report, either from their own ('proxy-proxy') or the patient's ('proxy-person') perspectives. It remains unclear which perspective proxies find most useful. Understanding this is important for designing measures that proxies can complete. We conducted an exploratory study on which perspective proxies find most useful and why, when reporting pain and physical function in dementia and symptoms in multiple sclerosis (MS).</p><p><strong>Methods: </strong>This study used data from two cross-sectional online surveys: one for proxies of people with MS and another for people with dementia. Proxies were asked to indicate which perspective they found most useful and why for communicating symptoms in MS, and pain or physical function in dementia, to healthcare professionals (HCPs). Quantitative responses were summarised using percentages; qualitative responses were analysed using content analysis.</p><p><strong>Results: </strong>55 proxies reported on MS symptoms, 29 on pain in dementia, and 33 on physical function in dementia. The most selected perspectives were: 35% (19/55) proxy-proxy for MS symptoms, 38% (11/29) proxy-person for pain and 39% (13/33) either of the perspectives for physical function. Proxy-person was valued for empathy and person-centredness, especially in reporting pain and MS symptoms. Proxy-proxy was appreciated for objectivity and reducing conflict, particularly in physical function. Using either perspective was considered most useful for balancing views and reducing misinterpretation in both conditions.</p><p><strong>Conclusion: </strong>Proxies' most useful perspectives vary slightly by domain and condition. Incorporating an understanding of how proxies approach the challenge of reporting may improve measure design.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 9","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13499833/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148797483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of quality of life after cardiac procedures: a mixed-methods study.","authors":"Niki Medendorp, Hilda Rijnhart-de Jong, Ilse Verstraaten, Tom Oirbans, Edgar Daeter, Henrico Wesselink, Roel Snijder, Daniela Schulz, Pepijn van der Voort, Christiaan Boerma, Dennis Duiker, Anja Machielse, Machteld Huber, Johanna Takkenberg, Dennis van Veghel","doi":"10.1007/s11136-026-04371-0","DOIUrl":"10.1007/s11136-026-04371-0","url":null,"abstract":"<p><strong>Purpose: </strong>Cardiovascular disease has a major impact on patients' lives. Cardiac procedures aim to improve patient health-related quality of life (HRQoL); however, some patients show little to no improvement afterwards. Changes in HRQoL are used to evaluate quality of care, and to enhance shared decision-making. We aimed to explore determinants predictive of HRQoL changes in patients undergoing a cardiac procedure.</p><p><strong>Methods: </strong>A stepwise, mixed-methods study was conducted. First, relevant determinants were identified and selected by performing a literature search and Delphi study. Next, a cross-sectional survey study was conducted among patients who underwent a cardiac procedure. The impact of determinants on changes in HRQoL (measured with the SF36-2/SF12-2, or Effect On Quality-Of-Life Questionnaire (AFEQT)) was examined.</p><p><strong>Results: </strong>Based on the literature search and Delphi study, 19 determinants were selected and subsequently observed among patients. In total, 1016 patients participated; 731 undergoing a CABG, PCI or SAVR (CPS-group), and 285 undergoing a PVI (PVI-group). In the CPS-group, 9 determinants were associated with significant changes in physical HRQoL and 9 determinants for mental HRQoL were found. In the PVI-group, significant determinants in the four AFEQT domains were found.</p><p><strong>Conclusion: </strong>This study shows that several psychological and social factors are significant predictors for patients' HRQoL after cardiac procedures. Addressing these factors in consultations is considered important when deciding about cardiac procedures. This may allow shared decision making, enhance patient expectations and be beneficial for choosing the most optimal treatment choice for the individual patient.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 9","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148797465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation of patient-reported outcome measures in oncology practice: a communication-centered qualitative study on patient and healthcare professional perspectives.","authors":"Linwei He, Anouk E W Teunissen, Nadine Bol, Kelly M de Ligt, Emiel Krahmer","doi":"10.1007/s11136-026-04378-7","DOIUrl":"10.1007/s11136-026-04378-7","url":null,"abstract":"<p><strong>Purpose: </strong>Patient-reported outcome measures (PROMs) are increasingly used in oncology to support patient-centered care, yet their implementation in routine practice remains inconsistent. Using a communication-centered perspective which conceptualizes PROMs implementation as a process of meaning exchange between patients, clinicians, and implementation staff, this study examined PROMs implementation as a multi-stage process and explored how it unfolds in real-life oncology care, drawing on both patient and healthcare professional perspectives.</p><p><strong>Methods: </strong>A qualitative interview study was conducted in the Netherlands with patients with cancer (n = 10) and healthcare professionals and implementation staff in oncology care (n = 7). Semi-structured interviews were informed by a communication-centered framework conceptualizing PROMs implementation as a multi-stage process. Data were analyzed using hybrid inductive-deductive thematic analysis.</p><p><strong>Results: </strong>Six interrelated stages of PROMs implementation were identified: (1) selecting and organizing PROMs use, (2) establishing purpose and motivation, (3) experiencing PROMs as a task, (4) making sense of results together, (5) applying PROMs information in care, and (6) evaluating and improving PROMs implementation. Findings showed that experiences at different stages were interconnected: processes occurring earlier in the implementation influence how PROMs were later understood, discussed, and used in care. Across roles, participants recognized PROMs' potential to support communication beyond clinical indicators, while also describing frustration when PROMs were collected but not meaningfully used. Patient and clinician engagement influenced one another across stages, reflecting the reciprocal nature of PROMs as a communication tool.</p><p><strong>Conclusion: </strong>PROMs implementation should be viewed as an interdependent, sequential process. Improving connections between stages is essential to realizing PROMs' communicative and patient-centered potential in oncology care. Practical strategies such as personalizing PROMs invitations, completing the feedback loop between PROMs results and patients, and integrating supportive tools for clinicians can help translate PROMs data into meaningful patient-centered dialogue.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 9","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13499845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148797498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design and evaluation of PROMIS^® fatigue and cognitive function short forms customized for adults with primary sclerosing cholangitis.","authors":"Donna M Evon, Laura Mkumba, Nicole Lucas, Li Lin, Lauren Wright, Kaya Merkler, Rachel Ciaves Gomel, Ricky Safer, Kallie Maloney, Christopher L Bowlus, Bryce B Reeve","doi":"10.1007/s11136-026-04364-z","DOIUrl":"10.1007/s11136-026-04364-z","url":null,"abstract":"<p><strong>Purpose: </strong>The goal of the Primary Sclerosing Cholangitis Symptom Assessment Project (PSC-SAP) is to develop reliable and valid PSC symptom measures for use in clinical trials. This article describes the process for customizing PROMIS^® Fatigue and PROMIS^® Cognitive Function short forms for adults with PSC.</p><p><strong>Methods: </strong>Relevant items from the PROMIS item banks were selected by matching findings from concept elicitation interviews. Participants were purposively selected for cognitive interviews if they were symptomatic with PSC-related fatigue or cognitive impairment and met general eligibility for PSC clinical trials. Interviews were recorded, transcribed, and coded. The precision of these PROMIS short forms for PSC to capture fatigue and cognitive function at different levels was analyzed.</p><p><strong>Results: </strong>Participants' (n = 22) open-ended descriptions of fatigue and cognitive impairment were consistent with prior concept elicitation interviews. From the 95-item PROMIS Fatigue item bank, 13 items were selected that directly aligned with fatigue concepts described during concept elicitation. Data from the cognitive interviews confirmed that both measures possessed strong content validity, with items perceived as clear, relevant, and comprehensive. The PROMIS Fatigue Short Form-PSC exceeded the 0.90 reliability threshold for T-scores between 36 and 79; the PROMIS Cognitive Function Short Form-PSC exceeded the 0.90 threshold between T-scores of approximately 22 and 60.</p><p><strong>Conclusion: </strong>This study demonstrated the strength of PROMIS item banks to design PROMIS Fatigue and Cognitive Function short forms for adults with PSC. Once the psychometric properties of the PROMIS short forms are confirmed, these measures may be used to evaluate symptoms in PSC research and clinical trials.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 9","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148797515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical activity, pain, and iron burden as independent correlates of quality of life in adults with beta-thalassemia major in the United Arab Emirates.","authors":"Yousef M Aljawarneh, Anu Kozhikunnel Kurian, Lama A Musallam","doi":"10.1007/s11136-026-04372-z","DOIUrl":"10.1007/s11136-026-04372-z","url":null,"abstract":"<p><strong>Purpose: </strong>To examine whether physical activity, iron burden (serum ferritin), and pain intensity are independently associated with multidimensional quality of life (QoL) among adults with beta-thalassemia major (BTM) in the United Arab Emirates.</p><p><strong>Methods: </strong>In this cross-sectional study, 250 eligible adults with transfusion-dependent BTM were enrolled from a specialized treatment center and included in the analyses. Participants completed the International Physical Activity Questionnaire-Short Form, the WHOQOL-BREF, and a Numeric Rating Scale for pain. Serum ferritin values were extracted from medical records. Multivariable general linear models were conducted to evaluate associations with WHOQOL-BREF physical, psychological, social, and environmental domain scores, adjusting for age, gender, employment status, chelator use, transfusion/chelation frequency, pain intensity, and serum ferritin.</p><p><strong>Results: </strong>Participants had a mean age of 31.7 ± 7.8 years; 45.6% reported low physical activity and 59.2% reported thalassemia-related pain. After adjustment, physical activity category was associated with physical and social QoL. Although the overall physical activity factor was not significantly associated with psychological QoL, participants with high physical activity had higher psychological QoL than those with low physical activity (p = 0.040). Pain intensity was independently associated with lower physical, psychological, and environmental QoL (all p ≤ 0.003), but not social QoL. Serum ferritin was not independently associated with QoL domains or pain intensity after adjustment.</p><p><strong>Conclusion: </strong>Among adults with BTM, physical activity and pain are important correlates of specific dimensions of quality of life, whereas serum ferritin does not appear to be directly associated with patient-reported QoL. These findings highlight the importance of promoting physical activity and addressing pain alongside biomedical management in adults with BTM.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 9","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148797474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric evaluation of separate anxiety and depression item banks - potential supplements to the EORTC CAT Core.","authors":"Morten Aa Petersen, Hugo Vachon, Neil K Aaronson, Johannes M Giesinger, Bernhard Holzner, Monika Sztankay, Mogens Groenvold","doi":"10.1007/s11136-026-04370-1","DOIUrl":"10.1007/s11136-026-04370-1","url":null,"abstract":"<p><strong>Purpose: </strong>The European Organisation for Research and Treatment of Cancer's computerized adaptive test instrument, the EORTC CAT Core, provides dynamic, individualised assessment across 14 health-related quality of life domains, including emotional functioning (EF), which encompasses anxiety and depression. When one of these symptoms is of primary interest, separate scores may better support clinical decision-making and increase measurement sensitivity. The aim here was to evaluate separate item banks for anxiety and depression as potential supplements to the EORTC CAT Core.</p><p><strong>Methods: </strong>Responses to 33 candidate EF items from 1,023 cancer patients were available from the original EF item bank project. Expert-based content classification was followed by psychometric analyses, including confirmatory factor analysis (CFA), item response theory (IRT) model calibration and evaluation, differential item functioning (DIF) analyses, and CAT simulations to assess measurement properties of the two item banks.</p><p><strong>Results: </strong>Experts allocated nine items to anxiety and 17 to depression while seven items were judged to assess something else. CFA supported unidimensionality for each item bank. All items demonstrated acceptable IRT model fit, and no DIF of practical relevance was identified. CAT simulations indicated greater measurement precision than fixed 1- and 2-item scales, with potential sample size savings of up to 30% for anxiety and 50% for depression.</p><p><strong>Conclusion: </strong>Well-functioning and psychometrically sound item banks can be formed for anxiety and depression, respectively. These findings support the use of separate anxiety and depression CATs as potential supplements to the EORTC CAT Core for more targeted assessment. Further studies are needed to confirm the content validity of the two item banks.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 9","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13469411/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148725727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation of an ePRO-based system supporting treatment readiness assessments in lung cancer care: a mixed-methods study.","authors":"Lasse Lybecker Scheel-Hincke, Johanne Dam Lyhne, Sanne Skovbjerg, Anne Skov Villadsen, Rasmus Blechingberg Friis, Mette Bøg Horup, Anne Mette Ølholm","doi":"10.1007/s11136-026-04363-0","DOIUrl":"10.1007/s11136-026-04363-0","url":null,"abstract":"<p><strong>Purpose: </strong>Electronic patient-reported outcomes (ePROs) have shown clinical benefits in oncology. Although widely used for symptom monitoring during and after cancer treatment, their potential to replace existing workflows, such as treatment readiness assessment without a direct clinical encounter, remains underexplored. Real-world evidence on the feasibility, acceptability, and resource implications of such approaches is limited. This study evaluated the implementation and use of an ePRO-based system to support treatment readiness assessments in lung cancer care.</p><p><strong>Methods: </strong>A mixed-methods study guided by the RE-AIM framework was conducted in routine lung cancer care at a Danish oncology department. Quantitative data from the ePRO platform and electronic health records were used to assess uptake and questionnaire completion. Qualitative data from field observations and semi-structured patient interviews were used to examine workflow integration, user experiences, and perceived value. Changes in staff time use before and after implementation were estimated by combining registry data, field observations, and staff input.</p><p><strong>Results: </strong>A total of 704 patients completed at least one ePRO questionnaire between December 2020 and March 2024, corresponding to 6,134 completed questionnaires. Treatment-level completion increased from 17.7% to 76.3%. In practice, ePRO data were used alongside blood test results, prior medical history, and clinical judgement to assess treatment readiness. The ePRO-based workflow was estimated to reduce nurses' time use by approximately 6 min per treatment. Patients and staff generally found the system meaningful and acceptable.</p><p><strong>Conclusion: </strong>The ePRO-based system appeared feasible to integrate into routine lung cancer care and supported more targeted treatment readiness assessments.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 9","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13469498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148725462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences in quality of life between early onset colorectal cancer patients compared to older patients: a qualitative study.","authors":"Julie Tucker, Brooke Turner, April Harrison, Rebecca Chamberlain, Devinder Raju, Elizabeth Murphy, Van M T Hoang","doi":"10.1007/s11136-026-04360-3","DOIUrl":"10.1007/s11136-026-04360-3","url":null,"abstract":"<p><strong>Purpose: </strong>Colorectal (bowel) cancer and its treatment can seriously affect a person's quality of life, including physical, social, work‑related, and emotional wellbeing. Young people with colorectal cancer experience worse psychological wellbeing, including marked emotional distress and prominent levels of anxiety. This disease is less common in people under 50, but cases of early‑onset colorectal cancer (EOCRC) are rising around the world. The object of this research was to derive a deeper understanding of the challenges and impact on quality of life faced by EOCRC compared to older patients following a colorectal cancer diagnosis.</p><p><strong>Method: </strong>Recruitment of participants from a larger mixed method project of surviving EOCRC patients from 2013 to 2023 and a matched sample of colorectal cancer patients. ¹ Participants invited to take part in an in‑depth semi-structured interview conducted by telephone or virtual meeting and audio taped, transcribed, and analysed using an interpretive phenomenological approach.</p><p><strong>Results: </strong>Twenty participants participated in interviews. Three themes (Headspace, physical impact and future) and eight corresponding sub themes encompassing poorer psychological quality of life, emotional distress and heightened anxiety faced by EOCRC. Barriers in current diagnostic services and treatment pathways more often reported by EOCRC.</p><p><strong>Conclusion: </strong>Older and younger cancer patients highlight a shift from active to passive social roles with both groups reporting substantial reductions in overall quality of life and role functioning, but longer lasting impact for EOCRC, who are focused on family, fertility, career, and survival. A review of current diagnostic services and treatment pathways is required, tailoring care for all patients and importantly address the unique needs of EOCRC.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 9","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148726871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A multidimensional item response theory analysis of the Seattle Angina Questionnaire: measurement precision, differential item functioning, and potential for item reduction.","authors":"Henry U Michael, Todd A Wilson, Danielle A Southern, Oluwagbohunmi A Awosoga, Michelle M Graham, Stephen B Wilton, Matthew T James, Lisa M Lix, Tolulope T Sajobi","doi":"10.1007/s11136-026-04368-9","DOIUrl":"10.1007/s11136-026-04368-9","url":null,"abstract":"<p><strong>Purpose: </strong>The Seattle Angina Questionnaire (SAQ) is widely used to measure disease-specific health status in coronary artery disease, but its psychometric properties have not been evaluated using multidimensional item response theory (MIRT). We evaluated the SAQ's dimensional structure, measurement precision, differential item functioning (DIF), and short form performance in a population-based cohort.</p><p><strong>Method: </strong>SAQ responses collected within two weeks of coronary angiography from 6,665 patients in the Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease (APPROACH) registry were analyzed using a confirmatory five-factor multidimensional graded response model. Item fit, local dependence, and conditional standard errors were evaluated. DIF by sex and age was examined using a two-step anchored multigroup approach. Short forms were derived based on discrimination, test information, and DIF magnitude.</p><p><strong>Result: </strong>The confirmatory five-factor model demonstrated good global fit (RMSEA = 0.031, CFI = 0.987, TLI = 0.982), supporting three distinct Physical Limitation dimensions: Basic, Moderate, and Strenuous. Empirical reliability ranged from 0.748 (Basic Physical Limitation) to 0.900 (Moderate Physical Limitation), with precision sufficient for individual-level interpretation in Moderate and Strenuous Physical Limitation. Moderate sex-related DIF was noted on Basic and Moderate Physical Limitation items, with females scoring lower than males. Age-related DIF was negligible to small. The 14-item short form preserved all five factors with theta correlations of 0.964 with the 18-item version.</p><p><strong>Conclusion: </strong>MIRT revealed three distinct Physical Limitation dimensions, enabling targeted functional monitoring. Precision gradients and sex-related DIF inform interpretation, and the 14-item short form is supported as the preferred version.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 9","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148689745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measuring satisfaction with orthotic and prosthetic devices.","authors":"Callie E Tyner, Aaron J Boulton, Jerry Slotkin, Pamela A Kisala, Ross Zafonte, W Lee Childers, Christopher L Dearth, Josef Butkus, David S Tulsky","doi":"10.1007/s11136-026-04366-x","DOIUrl":"10.1007/s11136-026-04366-x","url":null,"abstract":"<p><strong>Purpose: </strong>To develop a measure of satisfaction with orthoses and prostheses for the Limb Injury Measurement Battery for Quality of Life (LIMB-QOL).</p><p><strong>Methods: </strong>Items were developed to assess an individual's satisfaction with, and emotional and physical assimilation of, an orthosis and/or prosthesis. Items covered topics of satisfaction with device performance and aesthetics as well as user adaptation to a device, including usage, fit, and comfort. A pool of 65 items was administered to 471 individuals in the LIMB-QOL field testing/calibration study. Item response theory was used to evaluate and calibrate the new items. Test-retest reliability after 1-2 weeks was evaluated in a subsample.</p><p><strong>Results: </strong>From the original pool, 39 items were removed for content and 11 items were removed due to differential item functioning by type of injury/limb loss and device (orthosis vs. prosthesis). Following psychometric analysis, 15 items were calibrated as an item bank. These items exhibited acceptable internal consistency (α = 0.95) and fit to a unidimensional model. The final 15-item bank has strong psychometric properties (test-retest reliability α = 0.79), can be administered as a computerized adaptive test or 7-item short form, and is applicable to upper and lower injuries, limb loss and reconstruction, and orthotic and prosthetic device users.</p><p><strong>Conclusion: </strong>The LIMB-QOL Satisfaction with Orthosis/Prosthesis is a reliable measure, with evidence for validity in individuals with a variety of limb-affecting injuries and sudden-onset illnesses, and thus can be used broadly following major extremity trauma, and would be ideal for large-scale monitoring of QOL outcomes, although further evaluation of the validity for individuals with dysvascular or degenerative conditions is needed.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 9","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13451311/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148689759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}