Quality of Life Research最新文献

{"title":"Trajectories of health-related quality of life in youth with chronic physical illness and their siblings.","authors":"Dominique Basque, Karen A Patte, Scott T Leatherdale, Mark A Ferro","doi":"10.1007/s11136-026-04243-7","DOIUrl":"https://doi.org/10.1007/s11136-026-04243-7","url":null,"abstract":"","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 6","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147820205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of life among women of reproductive age during the accumulation of multiple chronic conditions.","authors":"Mohammad R Baneshi, Annette Dobson, Gita D Mishra","doi":"10.1007/s11136-026-04262-4","DOIUrl":"10.1007/s11136-026-04262-4","url":null,"abstract":"","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 6","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13136207/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147820197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential patterns of health-related quality of life among low- and high-income cancer survivors in South Korea: a latent class analysis.","authors":"Haein Lee, Bo Gyeong Lee","doi":"10.1007/s11136-026-04245-5","DOIUrl":"https://doi.org/10.1007/s11136-026-04245-5","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to identify subgroups of health-related quality of life (HRQoL) and examine predictors of latent class membership among low- and high-income cancer survivors using latent class analysis (LCA).</p><p><strong>Methods: </strong>We analyzed data from the Korea National Health and Nutrition Examination Survey (2013-2020), including 1075 cancer survivors. HRQoL patterns were identified using LCA based on the EuroQol five-dimension questionnaire. Analyses were conducted separately for low- and high-income groups to examine income-stratified HRQoL patterns. Sociodemographic characteristics and chronic disease status were included as covariates in the latent class models to examine predictors of class membership within each income group.</p><p><strong>Results: </strong>Income-stratified LCAs suggested differential HRQoL patterns. Three latent HRQoL classes were identified in the low-income group: Good HRQoL, Pain and Mobility Impairment, and Poor HRQoL. In the high-income group, two classes were identified: Good HRQoL and Pain and Mobility Impairment. While education was a common predictor in both groups, other predictors varied by income level. In the low-income group, older age, unemployment, and multimorbidity were significantly associated with impaired HRQoL classes, whereas female sex predicted membership in the Pain and Mobility Impairment class in the high-income group.</p><p><strong>Conclusion: </strong>These findings highlight differences in HRQoL patterns and associated factors across income-stratified groups of cancer survivors, underscoring the limitations of relying solely on average HRQoL scores in survivorship care. Survivorship strategies should be tailored to the differential HRQoL patterns and associated predictors identified within each income group, thereby promoting more targeted and equitable care for cancer survivors.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 6","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147820078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of life after tranexamic acid in subarachnoid hemorrhage: post-hoc analysis of the ULTRA trial.","authors":"Nadine Denneman, Tanvi Kamra, René Post, Maud A Tjerkstra, Menno R Germans, Mervyn D I Vergouwen, Korné Jellema, Radboud W Koot, Nyika D Kruyt, Jasper F C Wolfs, Dharmin Nanda, Bram Van Der Pol, Gerwin Roks, Loes J A Reichman, Paul J A M Brouwers, Vincent I H Kwa, Henri P Bienfait, Hieronymus D Boogaarts, Catharina J Klijn, René van den Berg, Bert A Coert, Janneke Horn, Charles B L M Majoie, Gabriël J E Rinkel, Yvo B W E M Roos, W Peter Vandertop, Dagmar Verbaan","doi":"10.1007/s11136-026-04263-3","DOIUrl":"10.1007/s11136-026-04263-3","url":null,"abstract":"<p><strong>Purpose: </strong>The ULTRA trial evaluated the impact of ultra-early and short-term tranexamic acid (TXA) treatment in patients with subarachnoid hemorrhage (SAH) and found no clinical benefit at six months. This post-hoc analysis examines whether TXA improves quality of life (QoL) at three and six months.</p><p><strong>Methods: </strong>The ULTRA trial was a randomized, controlled, multicenter study conducted from July 2013 to July 2019. Patients received either TXA or standard care. This analysis included patients who completed at least one QoL questionnaire. The primary endpoint was QoL, assessed using the EQ-5D-3L questionnaire at three and six months. Linear mixed models adjusted for confounders were used to analyze the association between TXA and QoL.</p><p><strong>Results: </strong>Of the 955 ULTRA patients, approximately 25% died, and 63% completed at least one QoL questionnaire. At three months, the TXA group had a mean EQ-5D index score of 0.75 versus 0.71 in the control group (p = 0.11) and a mean EQ-5D Visual Analogue Scale (VAS) score of 89 versus 86 (p = 0.10). At six months, the mean EQ-5D index score was 0.84 in the TXA group compared to 0.82 in the control group (p = 0.23), and the mean VAS was 92 in the TXA group compared to 89 in the control group (p = 0.13).</p><p><strong>Conclusion: </strong>Ultra-early and short-term TXA did not result in a significant improvement in QoL at three or six months in patients with SAH. Given the lack of benefit on both clinical outcome and QoL, routine use of TXA is not recommended.</p><p><strong>Trial registration: </strong>Netherlands Trial Register: NTR3272.</p><p><strong>Clinicaltrials: </strong>gov: NCT02684812.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 6","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13136198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147820120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"WOMAC-based recovery after total knee arthroplasty in a multiethnic Asian cohort: a 5-year registry-based study of interval-specific predictors of improvement.","authors":"Eau Liang Teow, Xin Zhang, Wei Loong Barry Tan, Chee Hoe Kong, Harish Sivasubramanian, Xun Li, Melvin Kian Loong Tan, Zi Qiang Glen Liau, Nick Bansback, Nan Luo, Wai San Wilson Tam, Ling Jie Cheng","doi":"10.1007/s11136-026-04276-y","DOIUrl":"10.1007/s11136-026-04276-y","url":null,"abstract":"<p><strong>Background: </strong>Patient-reported outcomes (PROs) after total knee arthroplasty (TKA) are well-documented in Western populations, but long-term recovery and its determinants in multiethnic Asian populations remain poorly understood. We aimed to characterise 5-year WOMAC recovery after TKA and to identify patient, clinical, and surgical factors associated with the odds of improvement at each consecutive postoperative interval in a multiethnic Asian cohort.</p><p><strong>Methods: </strong>This registry-based cohort study used prospectively collected data from a tertiary hospital in Singapore. We included 4964 consecutive cases with osteoarthritis undergoing primary TKA between December 1, 2008, and December 31, 2023. The primary outcomes were changes in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) total and subscale scores, measured at baseline and at 6 months, 1, 2, and 5 years postoperatively.</p><p><strong>Results: </strong>The mean (SD) total WOMAC score improved from 38.6 (15.1) at baseline to 7.5 (9.2) at 5 years. The greatest improvement occurred within the first 6 months (mean change, 27.6 points; P value < .001). In multivariable interval-specific analyses, older age (≥ 75 years; OR 0.55, 95% CI 0.39-0.79) and the presence of one or more comorbidities (OR 0.83, 95% CI 0.71-0.96) were independently associated with lower odds of long-term improvement. Interval-specific associations with ethnicity were also observed for pain and stiffness.</p><p><strong>Conclusions: </strong>In this large, multi-ethnic Asian cohort, TKA was associated with substantial and durable WOMAC improvements, primarily within the first 6 months. Interval-specific predictors of improvement were dominated by patient-level factors, notably age, comorbidity, and ethnicity, while surgical variables showed limited association. These findings support the potential value of patient-centred risk stratification and culturally responsive perioperative care in optimising long-term outcomes.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 6","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13136197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147820178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating real-time patient-reported outcomes in colorectal cancer care: development and evaluation of a concise clinical scorecard.","authors":"Despoina Kanata, Ling Y Chen, Ashley Foglia, Sarah Bober, Christina Lee, Mohammad Ali Abbass, Georgios Karagkounis, Maria Widmar, Iris H Wei, J Joshua Smith, Garrett M Nash, Martin R Weiser, Philip B Paty, Andrew J Vickers, Julio Garcia-Aguilar, Emmanouil Pappou","doi":"10.1007/s11136-026-04224-w","DOIUrl":"https://doi.org/10.1007/s11136-026-04224-w","url":null,"abstract":"","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 6","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147820203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health-related quality of life measures in incarcerated populations: a scoping review.","authors":"Habeba Talaat, Adam J N Raymakers, Ahmed M Bayoumi, Stefania Papatheodorou, Abd-Al-Wahab Khawaja, Christina Hanna, Claire Sethuram, Ethan Candler, Imaan Javeed, Iryna Artyukh, Paige Homme, Saadia Sediqzadah","doi":"10.1007/s11136-026-04217-9","DOIUrl":"https://doi.org/10.1007/s11136-026-04217-9","url":null,"abstract":"<p><strong>Purpose: </strong>Incarcerated populations face greater health challenges, including higher rates of communicable and mental diseases. However, traditional health measures like disease prevalence and life expectancy do not capture their physical, mental, emotional, and social well-being. This scoping review will summarize the health-related quality of life (HRQoL) outcomes in incarcerated populations using preference-based HRQoL instruments (and measures that can be used to derive utility scores), providing insights for health policies and economic evaluations.</p><p><strong>Methods: </strong>A scoping review was conducted following PRISMA-ScR guidelines. Six electronic databases and three health technology assessment agencies were searched for peer-reviewed studies reporting preference-based HRQoL or HRQoL scores that can be used to generate health state utility values in incarcerated populations. Eligibility and data extraction were performed by two independent researchers.Findings were synthesized to identify knowledge gaps.</p><p><strong>Results: </strong>Twenty-two articles met the inclusion criteria, primarily focusing on male and white populations. Ten studies targeted disease-specific populations, with mental health disorders (n = 7) being the most prevalent. Across studies, inmates generally reported lower HRQoL scores than the general population, especially those with mental health issues. Female and Indigenous inmates had lower HRQoL scores than male and non-Indigenous inmates.</p><p><strong>Conclusion: </strong>The variety in HRQoL instruments used, with each assessing different domains, hinders direct comparisons between studies. Validating instruments specific to incarcerated populations may be needed for future research. Overall, incarcerated populations, especially women and Indigenous inmates, demonstrate poorer HRQoL than the general population. There is a need for more diverse, inclusive studies to address these gaps.</p>","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 6","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147820210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of the novel nontuberculous mycobacterial pulmonary disease symptoms scale (NTM-SS).","authors":"E Henkle, N F Dieckmann, H Franklin, D Cella, G Megson, C L Daley, P A Flume, P J McShane, K L Winthrop, A L Quittner","doi":"10.1007/s11136-026-04227-7","DOIUrl":"https://doi.org/10.1007/s11136-026-04227-7","url":null,"abstract":"","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 6","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147820095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing content validity: challenges of conducting systematic reviews of patient-reported outcome measures and recommendations to improve the application of COSMIN guidance.","authors":"Rachel L Chambers, Silvia Lahuerta-Martín, Ana M Greco, Rachael Pattinson, Timothy Pickles, Jason Hassan, Lidwine B Mokkink","doi":"10.1007/s11136-026-04261-5","DOIUrl":"10.1007/s11136-026-04261-5","url":null,"abstract":"","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 6","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13136209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147820107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential of ASCOT-Carer for evaluating the quality of life of family caregivers for patients with Alzheimer's disease in Japan.","authors":"Shinichi Noto, Kentaro Yamato, Keisuke Onuki, Tomohiro Kondo","doi":"10.1007/s11136-026-04252-6","DOIUrl":"10.1007/s11136-026-04252-6","url":null,"abstract":"","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":"35 6","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13136206/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147820179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}