Psychiatric Quarterly最新文献

{"title":"Cognition Mediates the Association Between Meaning in Life and Depression: Sex-Differentiated Analysis in Europeans Aged 50 and Over.","authors":"Marcelo de Maio Nascimento, Adilson Marques, Élvio Rúbio Gouveia, Gerson Ferrari, Andreas Ihle","doi":"10.1007/s11126-025-10147-5","DOIUrl":"https://doi.org/10.1007/s11126-025-10147-5","url":null,"abstract":"<p><p>This study aimed to explore whether immediate recall, delayed recall, and verbal fluency mediated the relationship between meaning in life and depression in a large sample of older adults from 17 European countries. The study also sought to investigate potential differences in mediation trajectories by sex. The data used were from the eighth wave of the SHARE project (year 2019), involving 24,277 individuals (13,874 women). The variables analyzed were: meaning in life extracted from the CASP-19 scale, tests for immediate recall, delayed recall and verbal fluency, and depression (12-item EURO-D scale). Depression was more prevalent among women. For both sexes, meaning in life was positively associated with immediate recall, delayed recall, and verbal fluency, while meaning in life was negatively associated with depression, indicating its potential to alleviate depressive feelings. The three cognitive domains significantly mediated the relationship between meaning in life and depression. Differences in indirect mediation effects between men and women were identified in the pathways: meaning in life → delayed recall → depression and meaning in life → verbal fluency → depression. The total indirect models for men and women differed significantly.</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examination of Patient and Provider Satisfaction, Benefits, and Challenges with Psychiatric Outpatient and Hospital-Based Telehealth Treatment during the COVID-19 Pandemic.","authors":"Christina Marini, Margot H Steinberg, Carly D Miron, Matthew Irwin, Bryana L Schantz, David L Ginsberg, Charles R Marmar, Naomi M Simon, Paraskevi Noulas, Kristin L Szuhany","doi":"10.1007/s11126-025-10150-w","DOIUrl":"https://doi.org/10.1007/s11126-025-10150-w","url":null,"abstract":"<p><strong>Objective: </strong>During the COVID-19 pandemic, telemental health (TMH) use rapidly increased. Though patients report satisfaction with TMH, acceptability among different psychiatric providers (inpatient, outpatient, nurses) and for various diagnoses is less understood. This study aimed to expand understanding by examining TMH acceptability, benefits, and barriers for providers and patients during the early transition to TMH in the COVID-19 pandemic.</p><p><strong>Methods: </strong>Online anonymous surveys evaluated patient (n = 64) and provider (n = 39) satisfaction with and perceived benefits and challenges to TMH from October-December 2020 on 5-point Likert scales. Qualitative data was collected and themes identified.</p><p><strong>Results: </strong>Outpatient (3.97 ± 1.05) and inpatient (3.11 ± 1.6) providers, including nurses, reported high satisfaction with TMH, despite over 50% never having used TMH prior to the pandemic. TMH was viewed as acceptable across diagnoses, including serious mental illness and substance use. Provider-rated benefits of outpatient TMH versus in-person visits included COVID safety (mean difference[MD] = 3.05), travel (MD = 2.95), and reduced cancellations (MD = 1.81). Inpatient TMH similarly included COVID safety benefits (MD = 3.31), but also challenges related to team-based service provision (MD = 1.68) and working with trainees (MD = 1.19). Qualitative themes identified TMH challenges (e.g., technological: 56.7% patients, 66.7% providers) and benefits (e.g., convenience/flexibility: 80% patients, 81.5% providers).</p><p><strong>Conclusions: </strong>TMH was associated with high satisfaction for patients and across provider types and patient diagnoses. This study provides further support that TMH across clinical settings allows for greater flexibility and accessibility to evidence-based care, and ongoing benefits even outside the context of the COVID-19 pandemic. It suggests the benefits of ongoing training of staff and trainees in TMH.</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Impact of the ACT-Based Positive Psychology Intervention to Improve Happiness, Mental Health, and Well-Being.","authors":"Gökmen Arslan, Umut Aydoğdu, Kıvanç Uzun","doi":"10.1007/s11126-025-10145-7","DOIUrl":"https://doi.org/10.1007/s11126-025-10145-7","url":null,"abstract":"<p><p>This study aims to examine the effectiveness of ACT-based positive psychology intervention on young people's mental health and well-being. Existing literature offers limited insights into the impacts of ACT-based PPIs, particularly concerning young people. The study explores the potential of this intervention to enhance positive psychological outcomes such as subjective well-being, self-compassion, and optimism, while reducing negative psychological outcomes like pessimism, anxiety, depressive symptoms, and somatic symptoms, and improving resilience. Conducted at a state university, the study involved 42 participants between the ages of 19 and 23 who were assigned to experimental (n = 20) and control (n = 22) group. The experimental group participated in an 8-week ACT-based PPI program. Employing a longitudinal experimental design, the study included a pre-test, post-test, and a follow-up test approximately two years later. Results indicated that the experimental group experienced significant improvements in positive psychological outcomes and reductions in negative outcomes, with the effects sustained during the follow-up period. Notably, long-term enhancements in resilience and self-compassion were observed. Overall, this study provides important evidence of the effectiveness of ACT-based PPI in promoting young people's long-term outcomes, with implications for developing intervention programs to support their mental health and well-being.</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental Health Help-Seeking Among Young Internal Migrants in China: Shame as a Double-Edged Sword.","authors":"Xuhong Li, Kin-Kit Li","doi":"10.1007/s11126-025-10127-9","DOIUrl":"https://doi.org/10.1007/s11126-025-10127-9","url":null,"abstract":"<p><p>Young migrants in mainland China are vulnerable to mental health issues and are reluctant to seek help from professional sources. Shame is considered an important culture-specific emotion affecting professional help-seeking. The current study aimed to investigate the moderating role of shame in the association between psychological stress and help-seeking in young internal migrants in China. 415 internal migrants (mean age = 29.20; SD = 4.81) were recruited to participate in the survey study with oversampling of those who sought help before. Multiple linear regression and Zero-inflated Poisson regression models were used to examine the moderating effects of shame on the stress-intention and stress-behavior relations, respectively. Among the 65.0% of participants with high psychological stress, 62.6% of them never sought professional help for their mental health issues. The results demonstrate that shame significantly reduced the positive association between psychological stress and professional help-seeking behavior. Conversely, shame also played a protective role, mitigating the negative association between psychological stress and professional help-seeking intention. The findings underline the importance of addressing shame-related issue prior to therapy and developing promotion strategies to improve young migrants' mental health.</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Semaglutide Plus Metformin Versus Metformin Alone For Antipsychotic-Induced Weight Gain In Patients With Type 2 Diabetes Mellitus.","authors":"Catherine Vu, Raymond Thai, Dozie Dike, Bria Sydner","doi":"10.1007/s11126-025-10137-7","DOIUrl":"https://doi.org/10.1007/s11126-025-10137-7","url":null,"abstract":"<p><p>To determine whether combination therapy (semaglutide + metformin) is more efficacious than monotherapy (metformin alone) in reducing the risk of antipsychotic-induced weight gain (AIWG) in patients with Type 2 Diabetes Mellitus (T2DM). This was a single-center, retrospective study evaluating patients ≥ 18 years of age receiving care at Michael E. DeBakey Veterans Affairs Medical Center (MEDVAMC) from January 2021 to December 2022. Subjects were identified by use of antipsychotic (quetiapine, risperidone, paliperidone, olanzapine, clozapine) with concomitant use of monotherapy or combination therapy. Key exclusion criteria included other medications impacting weight, unstable medical illness, active substance use disorder, and dual antipsychotic use. The primary endpoint was defined as weight loss ≥ 5% from baseline. Secondary outcomes included BMI % difference and HbA1c difference from baseline. Data was analyzed using descriptive statistics. 31 patients were evaluated in each group for the final analysis. 38.7% (12/31) of patients in the monotherapy group achieved the primary outcome of weight loss ≥ 5% from baseline vs. 61.29% (19/31) in the combination group (p = 0.04). For secondary outcomes, the BMI % difference from baseline in the monotherapy group was -3.88% vs. -5.58% in the combination group (p = 0.129). The monotherapy group had a difference in HbA1c % from baseline of 0.14% vs -0.9% in the combination group (p = 0.007). Among T2DM patients on antipsychotics, more patients in the combination group achieved weight loss ≥ 5% within the study period compared to metformin monotherapy. Future research should account for non-diabetic patients, assess lifestyle factors, and exclude other psychotropic medications that may affect weight.</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144027026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive Behavioral Therapy Alone or in Combination with Eszopiclone in Comorbid Insomnia and Obstructive Sleep Apnea in Veterans with Posttraumatic Stress Disorder: A Randomized Trial.","authors":"Ali A El-Solh, Yolanda Lawson, Amber Martinson, Gregory Wilding","doi":"10.1007/s11126-025-10143-9","DOIUrl":"https://doi.org/10.1007/s11126-025-10143-9","url":null,"abstract":"<p><p>We sought to assess the augmentation of brief behavioral therapy for insomnia (BBTI) with eszopiclone (ESZ) over BBTI alone for the treatment of chronic insomnia on sleep quality, sleep indices, and continuous positive airway pressure (CPAP) adherence in PTSD veterans with COMISA. The pilot trial involved 53 PTSD patients (46 males and 7 females, mean age 48.2±8.3 years) with COMISA randomized to combination therapy of BBTI plus 2 weeks of eszopiclone (2 mg/d) or BBTI alone with follow-up visits conducted at 6 and 24 weeks. The main outcome measure was sleep quality assessed by the Pittsburgh Sleep Quality Index (PSQI). A significant decrease in PSQI scores was observed between baseline and 24 weeks for BBTI plus ESZ (-5.24 [95% CI, -6.55 to -3.94]; p < 0.001) and BBTI-only (-5.45 [95%CI, -6.75 to -4.14]; p < 0.001). No significant group allocation effects x time interactions were detected. Similar improvements were recorded for ISI between baseline and 24 weeks (BBTI plus ESZ (-8.32 [95%CI, -10.51 to -6.14]; p < 0.001) and BBTI-only (-8.64 [95%CI, -10.88 to -6.41]; p < 0.001)) with no interaction effect between treatment groups x time. Combination therapy produced a higher remission rate of insomnia at 6 weeks, with both interventions achieving comparable rates at 24 weeks. Results of the mixed effect models for CPAP use revealed no group x time interaction effects. In patients with COMISA, the combination of eszopiclone with BBTI resulted in comparable improvement in sleep quality of life to that achieved with BBTI-only therapy. Although the addition of eszopiclone to BBTI conferred an early benefit in remission rate of insomnia relative to BBTI, both modalities achieved similar outcomes at long-term follow-up. Clinical Trial Registration This study was registered with ClinicalTrials.gov (Identifier NCT03937713).</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the Romanian Version of Autism Spectrum Quotient (AQ) and Empathy Quotient (EQ) in the General Population.","authors":"Alexandra Dolfi, Darian Faur, Mihai-Rare Scălcău, Emilia-Maria Sorescu, Mugur-Daniel Ciumăgeanu, Cătălina Tudose","doi":"10.1007/s11126-025-10144-8","DOIUrl":"https://doi.org/10.1007/s11126-025-10144-8","url":null,"abstract":"<p><strong>Introduction: </strong>The diagnosis of Autism Spectrum Disorder (ASD) can be difficult to achieve, especially since the diagnostic criteria have changed in the last decade. This challenge is even greater for Romanian clinicians, as there are currently no screening tools validated for diagnosing ASD in adults within the Romanian population.</p><p><strong>Purpose: </strong>This study aims to validate two screening instruments used to identify autistic traits in the Romanian general population: the Autism Spectrum Quotient (AQ) and the Empathy Quotient (EQ).</p><p><strong>Methods: </strong>Data was collected by administering the Romanian version of the scales to a sample of 916 Romanian native speakers from the non-clinical population. 108 individuals were re-tested after 2 years. The scales were validated by determining their reliability with respect to the stability of the results and evaluating their construct and structural validity in correlation with the following instruments: QCAE (Questionnaire of Cognitive and Affective Empathy), PAQ (Perth Alexithymia Questionnaire) and BVAQ (Bermond-Vorst Alexithymia Questionnaire).</p><p><strong>Results: </strong>Our data revealed that, regarding reliability, the Romanian version of AQ presents slightly lower internal consistency compared to the original validation study. Concerning structural validity, confirmatory factor analysis (CFA) revealed suboptimal fit indices for the original 5-factor structure. Based on a subsequent exploratory factor analysis (EFA), a 2-factor solution returned improved fit indices.</p><p><strong>Conclusion: </strong>Despite employing more items to measure the constructs than needed, this study confirmed that both instruments present a valuable resource for clinicians working with neurodivergent patients, as interest in this area of pathology has increased greatly in Romania over the past few years. Practical implications and methodological issues regarding the two instruments are discussed.</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Underlying Dimensions of Borderline Personality Disorder: A Systematic Review of Factor Analytic Studies.","authors":"Alexandra Triantafyllou, George Konstantakopoulos, Pentagiotissa Stefanatou, Eleni Giannouli, Ioannis A Malogiannis","doi":"10.1007/s11126-025-10141-x","DOIUrl":"https://doi.org/10.1007/s11126-025-10141-x","url":null,"abstract":"<p><p>Borderline personality disorder (BPD) is considered to be a heterogeneous diagnostic entity, with multiple facets of the disorder influencing its course. Disentangling the structure of BPD criteria is fundamental to better understanding the disorder and targeting problematic behaviors. To identify and critically appraise factor analytic studies examining the structure of BPD criteria. A systematic review was conducted according to PRISMA guidelines. Three computerized databases (Pubmed, Scopus,PsycNET) were searched, resulting in the inclusion of 27 relevant studies. The unified model of BPD has been confirmed by a number of studies, while among multidimensional models, a three-factor model has also gained considerable empirical support. Multidimensional models of BPD tend to cluster together \"disordered self\" symptoms (identity disturbance and emptiness), affective symptoms (affective instability and anger), and behavioral symptoms (impulsivity and self-harming behaviors). Unidimensional and multidimensional models of the BPD structure are not necessarily in competition. An understanding of BPD as a unified diagnosis composed of three underlying dimensions, could serve the purpose of recognizing and targeting different aspects of the disorder, while maintaining a robust, and clinically useful diagnosis.</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143788706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Sleep Quality and Sleepiness in the Relationship Between Cognitive Flexibility and Fatigue.","authors":"Ozge Ozkutlu, Ozgu Inal Ozun","doi":"10.1007/s11126-025-10135-9","DOIUrl":"https://doi.org/10.1007/s11126-025-10135-9","url":null,"abstract":"<p><p>This study aimed to determine the pathways linking cognitive flexibility to fatigue through the serial mediation effect of sleep quality and sleepiness in 564 healthy adults using various scales, including the Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, Chalder Fatigue Scale, and Cognitive Flexibility Inventory. Analysis was performed using two mediating variables (sleep quality and sleepiness) with age and gender as covariates. The simple mediation effect was evaluated using the Causal Step. The indirect effect was examined using bootstrap method and Sobel test. The total and direct effects of cognitive flexibility on fatigue were both found to be statistically significant. The research model revealed three significant indirect effects: cognitive flexibility affecting fatigue through sleep quality, cognitive flexibility affecting fatigue through sleepiness and cognitive flexibility affecting fatigue through both sleep quality and sleepiness. Additionally, serial mediation analysis showed that the relationship between cognitive flexibility and fatigue is sequentially mediated by sleep quality and sleepiness (B = -0.064, SE = 0.013, 95% CI: -0.070 to -0.017). All effects were confirmed through the 95% confidence intervals, which did not include zero, and with significant p values. These findings highlight the role of sleep quality and sleepiness as serial mediators of the relationship between cognitive flexibility and fatigue. The study's major contribution is to provide insight on the independent and serial mediating role of sleep quality and sleepiness in the relationship between cognitive flexibility to fatigue.</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143788703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of Lifestyle Behaviors with Anxiety and Depression in Type 2 Diabetes Mellitus Patients with Hypertension: A Cross-Sectional Study.","authors":"Ziling Feng, Hongying Liu, Wenyan Zhang, Yamin Liu, Ni Xiong, Wenhang Chen, Jianzhou Yang, Xinyin Wu, Wenjie Dai","doi":"10.1007/s11126-025-10136-8","DOIUrl":"https://doi.org/10.1007/s11126-025-10136-8","url":null,"abstract":"<p><p>This study aimed to identify the prevalence of anxiety and depression, as well as the associations of lifestyle behaviors with anxiety and depression in type 2 diabetes mellitus (T2DM) patients with hypertension. This cross-sectional study was conducted in Hunan Province of China, with 475 participants included. Data on sociodemographic, lifestyle behaviors, and disease-related characteristics were collected. Anxiety and depression were assessed using self-report questionnaires. This study indicated that the prevalence of anxiety and depression was 37.47% (95% confidence interval [95% CI]: 33.37-42.07%) and 40.63% (95% CI: 36.43-45.26%), respectively. Multivariable logistic regression analyses showed that playing cards or mahjong (adjusted odds ratio [aOR] = 0.46 [95% CI: 0.28-0.76] and aOR = 0.57 [95% CI: 0.34-0.94] for anxiety and depression, respectively) and performing physical activity for > 30 min per day (aOR = 0.32 [95% CI: 0.19-0.52] and aOR = 0.23 [95% CI: 0.14-0.38] for anxiety and depression, respectively) were associated with lower odds of both anxiety and depression, while reading books or newspapers (aOR = 0.34, 95% CI: 0.12-0.93) were associated with lower odds of anxiety alone. Therefore, regular reading, social activities and physical activities can be considered as intervention targets for the prevention and management of anxiety and depression in T2DM patients with hypertension.</p>","PeriodicalId":20658,"journal":{"name":"Psychiatric Quarterly","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143780959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}