{"title":"[Eye Spy: What Red Eyes Could Reveal About Your Kidneys].","authors":"Pascal Gantenbein, Isabelle Binet, Regula Laux, Sascha Mathias Jung, Annette Enzler-Tschudy, Christian Kuhn","doi":"10.23785/PRAXIS.2025.04.009","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.04.009","url":null,"abstract":"<p><strong>Introduction: </strong>TINU syndrome (Tubulointerstitial Nephritis and Uveitis) is a rare autoimmune disorder that causes inflammation in the kidneys and eyes. It manifests as uveitis and impaired kidney function. Diagnosis is based on symptom correlation and kidney biopsy. Differential diagnoses include infectious and immunological conditions. Treatment primarily involves systemic corticosteroids and topical steroids for uveitis. Relapses may occur, especially in adults, while the prognosis in children tends to be more favorable.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 4","pages":"164-167"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144041506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2025-04-01DOI: 10.23785/PRAXIS.2025.04.005
Sofia Flores Borsari, Stefan Bilz
{"title":"[Drug-induced adrenal insufficiency].","authors":"Sofia Flores Borsari, Stefan Bilz","doi":"10.23785/PRAXIS.2025.04.005","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.04.005","url":null,"abstract":"<p><strong>Introduction: </strong>Many drugs may influence the hypothalamic-pituitary-adrenal axis (HPA-Axis) at different levels. Since the discovery of the pharmacological effect of glucocorticoids (GC) and the first application of cortisone (then known as \"Compound E\") in patients with rheumatoid arthritis in 1948, exogenous glucocorticoids have been the most common cause of drug-induced adrenocortical insufficiency. In the last few years, immune check point inhibitors (ICI) have become a new important cause. Due to the insidious and unspecific symptoms, which can also be a consequence of the underlying disease and its therapies, the diagnosis is often delayed. Regular screening by the attending physicians is essential for prompt recognition of the condition and reduction of the associated morbidity. This article summarizes the most common implicated drugs (GC, ICI and opioids) and the corresponding management recommendations.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 4","pages":"149-153"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143978748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2025-04-01DOI: 10.23785/PRAXIS.2025.04.008
Wiktoria Drozdz, Luis Manrique, Fatmir Rama, Jan Kellner, Christian Clarenbach, Katja Weiss, Beat Knechtle
{"title":"[Pulmonary cystic lesions in a young female patient].","authors":"Wiktoria Drozdz, Luis Manrique, Fatmir Rama, Jan Kellner, Christian Clarenbach, Katja Weiss, Beat Knechtle","doi":"10.23785/PRAXIS.2025.04.008","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.04.008","url":null,"abstract":"<p><strong>Introduction: </strong>Lymphangioleiomyomatosis (LAM) primarily affects women of childbearing age. Diagnosing LAM can be challenging due to nonspecific symptoms ranging from asymptomatic findings to life-threatening respiratory insufficiency. Typical cystic changes in the lungs are identifiable through imaging techniques. In addition to imaging, blood tests, including the measurement of Vascular Endothelial Growth Factor D (VEGF-D), as well as histopathological results from biopsies, can provide valuable information for diagnosing LAM. In this article, we discuss the case of a 31-year-old woman who was diagnosed with LAM incidentally.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 4","pages":"159-163"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2025-04-01DOI: 10.23785/PRAXIS.2025.04.002
Julius Popp, Tatjana Meyer-Heim, Markus Bürge, Michael M Ehrensperger, Ansgar Felbecker, Hans Pihan, Nadège Barro-Belaygues, Christian Chicherio, Bogdan Draganski, Gaby Bieri, Irene Bopp-Kistler, Andrea Brioschi, Matthias Brühlmeier, Karin Brügger, Gianclaudio Casutt, Valentina Garibotto, Petra Gasser, Dan Georgescu, Anton Gietl, Andrea Grubauer, Freimut Jüngling, Sonja Kagerer, Eberhard Kirsch, Vera Kolly, Gabriela Latour Erlinger, Andreas Monsch, Laura Rinke, Rafael Meyer
{"title":"[The Swiss Memory Clinics recommendations for the diagnosis of dementia - an update].","authors":"Julius Popp, Tatjana Meyer-Heim, Markus Bürge, Michael M Ehrensperger, Ansgar Felbecker, Hans Pihan, Nadège Barro-Belaygues, Christian Chicherio, Bogdan Draganski, Gaby Bieri, Irene Bopp-Kistler, Andrea Brioschi, Matthias Brühlmeier, Karin Brügger, Gianclaudio Casutt, Valentina Garibotto, Petra Gasser, Dan Georgescu, Anton Gietl, Andrea Grubauer, Freimut Jüngling, Sonja Kagerer, Eberhard Kirsch, Vera Kolly, Gabriela Latour Erlinger, Andreas Monsch, Laura Rinke, Rafael Meyer","doi":"10.23785/PRAXIS.2025.04.002","DOIUrl":"10.23785/PRAXIS.2025.04.002","url":null,"abstract":"<p><strong>Introduction: </strong>The early and accurate diagnosis is the basic prerequisite for timely, targeted and individually tailored counselling, treatment and support for people developing cognitive impairment. The association Swiss Memory Clinics (SMC) has elaborated detailed quality standards for the assessment of cognitive disorders, published them for the first time in 2018 and updated them in 2024. These recommendations present the current diagnostic guidelines and examination options, along with proposed standards for the relevant procedures. Single areas such as anamnesis, clinical examination, laboratory assessments, neuropsychological testing and neuroradiological procedures are discussed as part of the standard diagnostics and the complementary investigation methods for differential diagnostics. Furthermore, the disclosure of the diagnosis and counselling are now described as an integral part of the diagnostic process. The most important objectives of the recommendations for the diagnosis of dementia disorders remain to enable high-quality early and accurate diagnostics of cognitive disorders throughout Switzerland; and to provide a practical guide for clinicians in primary care and memory clinics.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 4","pages":"127-136"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144041691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2025-03-01DOI: 10.23785/PRAXIS.2025.03.001
Thomas Rosemann, Andrea Rosemann
{"title":"Statine führen auch in hohem Alter in der Primärprävention zu weniger Herz-Kreislauf-Erkrankungen.","authors":"Thomas Rosemann, Andrea Rosemann","doi":"10.23785/PRAXIS.2025.03.001","DOIUrl":"10.23785/PRAXIS.2025.03.001","url":null,"abstract":"<p><strong>Introduction: </strong></p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 3","pages":"84"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2025-03-01DOI: 10.23785/PRAXIS.2025.03.008
Benjamin Hutter, Adrian Rohrbasser
{"title":"[Off Course with Delirium - Medication Challenges].","authors":"Benjamin Hutter, Adrian Rohrbasser","doi":"10.23785/PRAXIS.2025.03.008","DOIUrl":"10.23785/PRAXIS.2025.03.008","url":null,"abstract":"<p><strong>Introduction: </strong>A 75-year-old patient admitted to geriatric rehabilitation after a fall showed symptoms initially misinterpreted as hyperactive delirium. After he experienced tonic-clonic seizures, it was discovered he had been taking high doses of amitriptyline, which was missed during the medication history. The diagnosis was revised to antidepressant withdrawal syndrome upon review.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 3","pages":"115-118"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2025-03-01DOI: 10.23785/PRAXIS.2025.03.005
Dominique Scherer, Corinna Schönweiss, Mirjam de Roche, Franca Flubacher, Sandra Koehli Weber, Angelika Noethiger, Thomas Goetz, Tanja Kudrnovsky, Philip Tarr
{"title":"[Norovirus - an update for practitioners].","authors":"Dominique Scherer, Corinna Schönweiss, Mirjam de Roche, Franca Flubacher, Sandra Koehli Weber, Angelika Noethiger, Thomas Goetz, Tanja Kudrnovsky, Philip Tarr","doi":"10.23785/PRAXIS.2025.03.005","DOIUrl":"10.23785/PRAXIS.2025.03.005","url":null,"abstract":"<p><strong>Introduction: </strong>Norovirus is one of the most infectious pathogens of all. Norovirus often poses a major logistical challenge for medical practices and hospitals in terms of isolation, visiting restrictions, material requirements, cleaning services, time off for sick staff etc. Serious complications are rare, but those affected by Norovirus can feel surprisingly ill. Dehydration and its consequences can occur, especially in the very old and very young.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 3","pages":"99-104"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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