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[The slightly different neck pain]. [颈部疼痛略有不同]。
Praxis Pub Date : 2026-02-01 DOI: 10.23785/PRAXIS.2026.02.008
Thomas Reich, Bernhard Blum, Lukas Zimmerli
{"title":"[The slightly different neck pain].","authors":"Thomas Reich, Bernhard Blum, Lukas Zimmerli","doi":"10.23785/PRAXIS.2026.02.008","DOIUrl":"10.23785/PRAXIS.2026.02.008","url":null,"abstract":"<p><strong>Introduction: </strong>Thrombosis of the jugular vein and upper extremities are much rarer than thrombosis of the lower extremities. The diagnostic tool of choice is duplex sonography of the vessels. A thorough clarification of the cause is necessary after diagnosis if an obvious cause is not initially found. The focus here should be on searching for malignancy as well as hypercoaguability. The recommended minimum duration of anticoagulation with low-molecular-weight heparin is at least 3 months for primary thromboses of the upper extremities and 6 months for secondary thromboses. Rivaroxaban therapy is also a suitable option for outpatient management.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 2","pages":"60-64"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[(Chemo-)Preventive strategies for skin cancer: current state of knowledge and implications for daily practice]. [（化学）皮肤癌的预防策略：目前的知识状况及其对日常实践的影响]。
Praxis Pub Date : 2026-02-01 DOI: 10.23785/PRAXIS.2026.02.003
Ainoa Galdos, Reinhard Dummer
{"title":"[(Chemo-)Preventive strategies for skin cancer: current state of knowledge and implications for daily practice].","authors":"Ainoa Galdos, Reinhard Dummer","doi":"10.23785/PRAXIS.2026.02.003","DOIUrl":"10.23785/PRAXIS.2026.02.003","url":null,"abstract":"<p><strong>Introduction: </strong>In view of rising incidence rates worldwide, the prevention of skin cancer is a central pillar of public health. While UV protection forms the basis of primary prevention, pharmacological strategies (chemoprevention) are becoming increasingly important. This paper provides a practice-oriented synthesis of current evidence, ranging from behavioural prevention and systemic approaches with nicotinamide and retinoids to experimental strategies such as immune checkpoint inhibitors and DNA repair enzymes.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 2","pages":"38-42"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Exertional syncope: A diagnosis of long QT syndrome. A practice-oriented case report on risk stratification and management]. 劳力性晕厥：长QT综合征的诊断。以实践为导向的风险分层与管理案例报告[j]。
Praxis Pub Date : 2026-02-01 DOI: 10.23785/PRAXIS.2026.02.005
Matus Brecka, Miroslava Brecka, Filipe Patricio, Laurent M Haegeli, Jan Berg
{"title":"[Exertional syncope: A diagnosis of long QT syndrome. A practice-oriented case report on risk stratification and management].","authors":"Matus Brecka, Miroslava Brecka, Filipe Patricio, Laurent M Haegeli, Jan Berg","doi":"10.23785/PRAXIS.2026.02.005","DOIUrl":"10.23785/PRAXIS.2026.02.005","url":null,"abstract":"<p><strong>Introduction: </strong>We present the case of a 22-year-old medical student who experienced repeated episodes of syncope during physical exertion. Ini-tial investigations, including a neurological assessment and cardiac examinations involving electrocardiograms (ECGs) and Holter monitoring, were normal. During a subsequent volleyball match, however, she suffered cardiac arrest and required resuscitation and defibrillation with an automated external defibrillator (AED). Analysis of the AED recording revealed ventricular fibrillation (VF) and prompted further diagnostic testing. Long QT syndrome (LQTS) was diagnosed based on the clinical presentation, a prolonged QTc interval on the ECG and documented cardiac arrest with VF. Subsequent genetic testing identified a pathogenic variant in the KCNQ1 gene, confirming the diagnosis of type 1 LQTS. The patient was treated with beta blockers, and an implantable cardioverter-defibrillator (ICD) was implanted. This case highlights the diagnostic and prognostic significance of exercise-induced syncope as a high-risk symptom requiring careful cardiological evaluation, even when initial investigations are unremarkable. It emphasises the high didactic value of AED data analysis and illustrates the application of current guidelines in the management of cardiac channelopathies.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 2","pages":"45-49"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eine Flüssigkeitsrestriktion bei Patienten mit einer Herz­insuffizienz scheint keinen positiven Effekt zu haben. 心力衰竭患者的液体限制似乎没有积极的效果。
Praxis Pub Date : 2026-02-01 DOI: 10.23785/PRAXIS.2026.02.001
Johann Steurer
{"title":"Eine Flüssigkeitsrestriktion bei Patienten mit einer Herz­insuffizienz scheint keinen positiven Effekt zu haben.","authors":"Johann Steurer","doi":"10.23785/PRAXIS.2026.02.001","DOIUrl":"10.23785/PRAXIS.2026.02.001","url":null,"abstract":"<p><strong>Introduction: </strong></p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 2","pages":"29"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Modern treatment of type 2 diabetes: 3 medications and 3 targets]. 2型糖尿病的现代治疗：3种药物和3个靶点。
Praxis Pub Date : 2026-02-01 DOI: 10.23785/PRAXIS.2026.02.004
Peter Wiesli
{"title":"[Modern treatment of type 2 diabetes: 3 medications and 3 targets].","authors":"Peter Wiesli","doi":"10.23785/PRAXIS.2026.02.004","DOIUrl":"10.23785/PRAXIS.2026.02.004","url":null,"abstract":"<p><strong>Introduction: </strong>Modern treatment of type 2 diabetes considers the use of three medications in all patients regardless of HbA1c (metformin, SGLT-2i, and GLP-1(+)-RA) as well as achieving three target values (HbA1c, blood pressure, and LDL cholesterol). These three target values are set individually. Ideally, most patients with type 2 diabetes should have HbA1c  6.5 %, blood pressure  130/80 mmHg, and LDL cholesterol  1.8 mmol/l. In patients with established cardiovascular disease should have LDL cholesterol  1.4 mmol/l.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 2","pages":"43-44"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A Rare Differential Diagnosis of Multiple Pulmonary Nodules]. 【肺多发结节的罕见鉴别诊断】。
Praxis Pub Date : 2026-02-01 DOI: 10.23785/PRAXIS.2026.02.006
Melanie Bühlmann, Thomas Langenegger, Wilhelm Nimphius, Michael Bodmer
{"title":"[A Rare Differential Diagnosis of Multiple Pulmonary Nodules].","authors":"Melanie Bühlmann, Thomas Langenegger, Wilhelm Nimphius, Michael Bodmer","doi":"10.23785/PRAXIS.2026.02.006","DOIUrl":"10.23785/PRAXIS.2026.02.006","url":null,"abstract":"<p><strong>Introduction: </strong>We report A 53-year-old longstanding smoker and stonemason, who has been treated with methotrexate since 2017 for seropositive rheumatoid arthritis (RA), who presented to the emergency department of the Zuger Kantonsspital with cough, aching limbs and fever. During the investigations, bilateral apical pulmonary infiltrates and nodular changes were found. After extensive examinations, the diagnosis of Caplan syndrome was made.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 2","pages":"50-52"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bei Meniskusriss und Knieschmerzen sind Übungen zu Hause gleich wirksam wie aufwendigere Therapien. 对于半月板撕裂和膝盖疼痛，在家锻炼和更复杂的治疗一样有效。
Praxis Pub Date : 2026-01-01 DOI: 10.23785/PRAXIS.2026.01.001
Johann Steurer
{"title":"Bei Meniskusriss und Knieschmerzen sind Übungen zu Hause gleich wirksam wie aufwendigere Therapien.","authors":"Johann Steurer","doi":"10.23785/PRAXIS.2026.01.001","DOIUrl":"10.23785/PRAXIS.2026.01.001","url":null,"abstract":"<p><strong>Introduction: </strong></p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147271818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Phobic vertigo: history, diagnosis and interdisciplinary therapy]. [恐怖性眩晕：病史、诊断和跨学科治疗]。
Praxis Pub Date : 2026-01-01 DOI: 10.23785/PRAXIS.2026.01.003
Sarah Schiebler, Elisabeth Schafflützel
{"title":"[Phobic vertigo: history, diagnosis and interdisciplinary therapy].","authors":"Sarah Schiebler, Elisabeth Schafflützel","doi":"10.23785/PRAXIS.2026.01.003","DOIUrl":"10.23785/PRAXIS.2026.01.003","url":null,"abstract":"<p><strong>Introduction: </strong>Phobic dizziness, also known as functional or somatoform dizziness, is a common and distressing condition that often lacks an identifiable organic cause. It poses a diagnostic and therapeutic challenge because of overlapping somatic, vestibular, and psychiatric factors. This article provides a historical context, describes the clinical picture, and outlines the current diagnostic approaches. Special focus is given to interdisciplinary collaboration and evidence-based treatment options, particularly cognitive behavioral therapy. The article concludes with a set of practice-relevant take-home messages for general practitioners.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 1","pages":"7-10"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147271844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Persistent electrolyte deficiency in an oncology patient]. [1例肿瘤患者持续电解质缺乏]。
Praxis Pub Date : 2026-01-01 DOI: 10.23785/PRAXIS.2026.01.005
Nicole Maurer, Katrin Ledergerber, Barbara Denecke, Christian Kuhn
{"title":"[Persistent electrolyte deficiency in an oncology patient].","authors":"Nicole Maurer, Katrin Ledergerber, Barbara Denecke, Christian Kuhn","doi":"10.23785/PRAXIS.2026.01.005","DOIUrl":"10.23785/PRAXIS.2026.01.005","url":null,"abstract":"<p><strong>Introduction: </strong>We report the case of a 47-year-old patient with a dedifferentiated mediastinal-thoracic liposarcoma who developed electrolyte disturbances during chemotherapy with Ifosfamide and Doxorubicin. Initially, a refeeding syndrome was suspected, supported by hypokalemia, hypomagnesemia, and hypophosphatemia. However, the prolonged course of electrolyte abnormalities, along with the presence of normoglycemic glucosuria and proteinuria, were not consistent with this diagnosis. Over time, a partial Fanconi syndrome was confirmed, reflecting a proximal tubular dysfunction - a well-known complication of Ifosfamide therapy. Notably, standard markers of kidney function, such as eGFR, remained within normal limits early in the course, highlighting the importance of sensitive early indicators like electrolyte abnormalities and glucosuria. Early urine diagnostics (ideally prior to the initiation of electrolyte replacement) are essential for recognizing and classifying this potentially serious adverse effect.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 1","pages":"16-19"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147271776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A rare differential diagnosis for pulmonary calcifications]. 【肺钙化的罕见鉴别诊断】。
Praxis Pub Date : 2026-01-01 DOI: 10.23785/PRAXIS.2026.01.006
Johanna-Nele Brendgens
{"title":"[A rare differential diagnosis for pulmonary calcifications].","authors":"Johanna-Nele Brendgens","doi":"10.23785/PRAXIS.2026.01.006","DOIUrl":"10.23785/PRAXIS.2026.01.006","url":null,"abstract":"<p><strong>Introduction: </strong>A 77-year-old patient developed community-acquired pneumonia four times within two years. During the work-up, the CT chest showed typical signs of dendriform pulmonary ossification (DPO), a rare disease characterized by bone formation in the lung tissue. DPO usually occurs in chronic lung damage, its clinical significance is still unclear, but it could become more relevant with increasing high-resolution diagnostics.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 1","pages":"20-22"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147271764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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