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[Fluoroquinolone-associated disability after taking ciprofloxacin]. [服用环丙沙星后氟喹诺酮类药物相关残疾]。
Praxis Pub Date : 2025-09-01 DOI: 10.23785/PRAXIS.2025.08_09.005
Raffaele Piazza, Katja Weiss, Thomas Rosemann, Beat Knechtle
{"title":"[Fluoroquinolone-associated disability after taking ciprofloxacin].","authors":"Raffaele Piazza, Katja Weiss, Thomas Rosemann, Beat Knechtle","doi":"10.23785/PRAXIS.2025.08_09.005","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.08_09.005","url":null,"abstract":"<p><strong>Introduction: </strong>Ciprofloxacin is among the most commonly prescribed Fluoroquinolones. Side effects of Fluoroquinolones include tendinopathies, ar-rhythmias, gastrointestinal discomfort, and neurological symptoms. The definition of a \"Fluoroquinolone-associated disability\" includes dis-ability, symptoms in several body systems and duration of symptoms after discontinuation of the antibiotic. The pathophysiology of this disease is probably due to a damage to the redox system. We report on a 41-year-old patient who felt pain in his Achilles tendons three days after starting to take ciprofloxacin (of a total of 3 g) and presented as an emergency. In the course of the disease, the pain became chronically disabling and the patient developed paresthesia of both extremities and intermittent heart palpitations. The only tolerated pain medication was Pregabalin. Several MRI examinations showed minimal peritendinitis and irritation of the Achilles tendons. Blood samples indicated probable intracellular damage at low intracellular ATP and coenzyme Q10 values.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 8-9","pages":"326-330"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Treatment recommendations for chronic insomnia - cognitive behavioural therapy as first-line treatment]. [慢性失眠的治疗建议-认知行为疗法作为一线治疗方法]。
Praxis Pub Date : 2025-09-01 DOI: 10.23785/PRAXIS.2025.08_09.003
Helen Slawik, Jens G Acker, Christine Blume, Anna Castelnovo, Katerina Espa Cervena, Miriam Gerstenberg, Elisabeth Hertenstein, Christian Imboden, Thorsten Mikoteit, Christian Mikutta, Lampros Perogamvros, Tifenn Raffray, Carolin Reichert, Verena Reiss, Carlotta L Schneider, Steffi Weidt, Cristina Zunzunegui, Martin Hatzinger, Christoph Nissen, Dagmar A Schmid
{"title":"[Treatment recommendations for chronic insomnia - cognitive behavioural therapy as first-line treatment].","authors":"Helen Slawik, Jens G Acker, Christine Blume, Anna Castelnovo, Katerina Espa Cervena, Miriam Gerstenberg, Elisabeth Hertenstein, Christian Imboden, Thorsten Mikoteit, Christian Mikutta, Lampros Perogamvros, Tifenn Raffray, Carolin Reichert, Verena Reiss, Carlotta L Schneider, Steffi Weidt, Cristina Zunzunegui, Martin Hatzinger, Christoph Nissen, Dagmar A Schmid","doi":"10.23785/PRAXIS.2025.08_09.003","DOIUrl":"10.23785/PRAXIS.2025.08_09.003","url":null,"abstract":"<p><strong>Introduction: </strong>In addition to the treatment recommendations published by the Special Interest Group (SIG) \"Mental Health\" (formerly \"Sleep Psychiatry\") of the Swiss Society for Sleep Research, Sleep Medicine and Chronobiology (SGSSC), the following article focusses on cognitive behavioural therapy for insomnia (CBT-I), its evidence, implementation and application, including in shift work, patients on medication, older people, various formats and non-pharmacological alternatives. Chronic insomnia is a disorder characterised by hyperarousal rather than sleep deprivation. The most effective treatment is bedtime restriction. This can be accompanied by increased daytime sleepiness and concentration deficits, which can be challenging. Furthermore, it is a challenge to find activities for the time that becomes available. The number of therapy places is still insufficient. However, it has been shown that CBT-I is also effective in shortened formats, digitally or when carried out by other professional groups.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 8-9","pages":"313-320"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Severe phototoxic side effects of pirfenidone]. [吡非尼酮严重的光毒性副作用]。
Praxis Pub Date : 2025-09-01 DOI: 10.23785/PRAXIS.2025.08_09.006
Ava Bode, Myriam Wyss Fopp, Jean-Luc Kurzen
{"title":"[Severe phototoxic side effects of pirfenidone].","authors":"Ava Bode, Myriam Wyss Fopp, Jean-Luc Kurzen","doi":"10.23785/PRAXIS.2025.08_09.006","DOIUrl":"10.23785/PRAXIS.2025.08_09.006","url":null,"abstract":"<p><strong>Introduction: </strong>This case report describes a phototoxic drug reaction in an 81-year-old patient taking the antifibrotic drug pirfenidone for the treatment of idiopathic pulmonary fibrosis. After two hours of sun exposure with sunscreen (SPF 50), the patient developed pruritic, erythematous and scaly lesions on the sun-exposed areas (face, neck, hands and forearms). Physical examination revealed an erythematous exanthema with coarse lamellar scale. A phototoxic reaction to pirfenidone was suspected based on the clinical presentation and distribution pattern. Treatment with topical corticosteroids and discontinuation of pirfenidone led to a marked improvement in symptoms. This case highlights the potential phototoxic risks of pirfenidone, which should be considered especially in dermatological practice where the drug is less known. In addition, important differential diagnoses are outlined and discussed.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 8-9","pages":"331-333"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Work-related asthma]. 与工作相关的哮喘。
Praxis Pub Date : 2025-09-01 DOI: 10.23785/PRAXIS.2025.08_09.004
Celine Schumacher, Felix Mangold, Holger Dressel
{"title":"[Work-related asthma].","authors":"Celine Schumacher, Felix Mangold, Holger Dressel","doi":"10.23785/PRAXIS.2025.08_09.004","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.08_09.004","url":null,"abstract":"<p><strong>Introduction: </strong>Bronchial asthma is a well-known and common disease. However, there is less knowledge about the fact that asthma can also have an association with the profession. However, this is very relevant because young patients who are in the middle of their working lives are often affected and suffer far-reaching consequences if a diagnosis of occupational asthma is made. The consequences are of a health as well as of a socio-economic nature. Since the asthma symptoms are present inconsistently and corresponding questions about the job may not be asked in the anamnesis, the workplace association is sometimes misunderstood and the diagnosis is therefore delayed. In this article we would like to raise medical awareness of work-related asthma, focus on occupational asthma and the steps to clarify it and finally explain the further procedure regarding suitability for work.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 8-9","pages":"321-325"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ist eine reduzierte DOAK-Dosis bei VTE-Patienten mit hohem ­Rezidivrisiko der vollen Dosis nicht unterlegen? 在复发风险高的VTE患者中，减少DOAK剂量不会低于全剂量吗？
Praxis Pub Date : 2025-09-01 DOI: 10.23785/PRAXIS.2025.08_09.001
Rahel Eberle, Thomas Rosemann
{"title":"Ist eine reduzierte DOAK-Dosis bei VTE-Patienten mit hohem ­Rezidivrisiko der vollen Dosis nicht unterlegen?","authors":"Rahel Eberle, Thomas Rosemann","doi":"10.23785/PRAXIS.2025.08_09.001","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.08_09.001","url":null,"abstract":"<p><strong>Introduction: </strong></p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 8-9","pages":"307"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A case of acute fascioliasis in a traveler returning from Australia and Vanuatu]. [1例从澳大利亚和瓦努阿图返回的旅行者感染急性片形吸虫病]。
Praxis Pub Date : 2025-09-01 DOI: 10.23785/PRAXIS.2025.08_09.008
Michelle Küting, Irene Abela, Felix Grimm, Marisa Kälin
{"title":"[A case of acute fascioliasis in a traveler returning from Australia and Vanuatu].","authors":"Michelle Küting, Irene Abela, Felix Grimm, Marisa Kälin","doi":"10.23785/PRAXIS.2025.08_09.008","DOIUrl":"10.23785/PRAXIS.2025.08_09.008","url":null,"abstract":"<p><strong>Introduction: </strong>A patient presented with fever and upper abdominal pain after returning from Australia and Vanuatu. Pronounced eosinophilia served as a diagnostic clue, leading to a successful treatment of acute fascioliasis with Triclabendazole. Following the therapy, the patient experienced complete symptom relief.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 8-9","pages":"337-341"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Symptomatic cholecystolithiasis after cholecystectomy]. [胆囊切除术后症状性胆囊结石]。
Praxis Pub Date : 2025-09-01 DOI: 10.23785/PRAXIS.2025.08_09.007
Fabiola Lugano, Alexander Böhler, Jan Borovicka, Thomas Steffen, Stephan Brand
{"title":"[Symptomatic cholecystolithiasis after cholecystectomy].","authors":"Fabiola Lugano, Alexander Böhler, Jan Borovicka, Thomas Steffen, Stephan Brand","doi":"10.23785/PRAXIS.2025.08_09.007","DOIUrl":"10.23785/PRAXIS.2025.08_09.007","url":null,"abstract":"<p><strong>Introduction: </strong>In rare cases, dilatation of the remaining cystic duct remnant after cholecystectomy can lead to a neogallbladder, in which gallstones can recur and cause further biliary problems (such as choledocholithiasis). The differential diagnosis of a \"neogallbladder\" should therefore be considered in cases of biliary colic even after cholecystectomy.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 8-9","pages":"334-336"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Nurse Practitioners and Physician Associates in Swiss Healthcare]. [瑞士医疗保健的执业护士和医师协会]。
Praxis Pub Date : 2025-09-01 DOI: 10.23785/TU.2025.08_09.002
Jessica Gaylord, Judith Weiss, Janette Ribaut, Frank Zimmermann, Sonja Beckmann, Sabina De Geest, Isabelle Gisler, Anja Hermann, Kathrin Horlacher, Rahel Käufeler, Susanne König, Jörg Leuppi, Anita Manser, Oliver Mauthner, André Nienaber, Franziska Perini, Melanie Capaul-Schmocker, Michael Simon, Caroline Stade, Markus Wepf, Franziska Zúñiga
{"title":"[Nurse Practitioners and Physician Associates in Swiss Healthcare].","authors":"Jessica Gaylord, Judith Weiss, Janette Ribaut, Frank Zimmermann, Sonja Beckmann, Sabina De Geest, Isabelle Gisler, Anja Hermann, Kathrin Horlacher, Rahel Käufeler, Susanne König, Jörg Leuppi, Anita Manser, Oliver Mauthner, André Nienaber, Franziska Perini, Melanie Capaul-Schmocker, Michael Simon, Caroline Stade, Markus Wepf, Franziska Zúñiga","doi":"10.23785/TU.2025.08_09.002","DOIUrl":"10.23785/TU.2025.08_09.002","url":null,"abstract":"<p><strong>Introduction: </strong>Physician Associates (PAs) and Nurse Practitioners (NPs) are healthcare professionals with advanced clinical skills who play a key role in strengthening integrated care and mitigating physician shortages. PAs hold a CAS or MAS (15-60 ECTS) and support physicians by taking on specific responsibilities (task shifting) to improve efficiency and ensure high-quality care. NPs have a Master of Science in Nursing (90-180 ECTS), and work with physicians (task-sharing) to care for a defined population, establishing diagnoses, managing treatment, and providing self-management support. PAs and NPs work in both inpatient and outpatient settings. Their training, competencies and scopes of practice differ; allowing them to complement each other. National regulation and tariff structures are necessary for both professions to reach their full potential.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 8-9","pages":"308-312"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Delayed bone healing after osteotomy - what the family history revealed]. [截骨后骨愈合延迟-家族史显示]。
Praxis Pub Date : 2025-07-01 DOI: 10.23785/PRAXIS.2025.07.008
Johanna Kuppinger
{"title":"[Delayed bone healing after osteotomy - what the family history revealed].","authors":"Johanna Kuppinger","doi":"10.23785/PRAXIS.2025.07.008","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.07.008","url":null,"abstract":"<p><strong>Introduction: </strong>A 35-year-old woman presented with delayed bone healing after periacetabular osteotomy, despite appropriate postoperative unloading and vitamin D supplementation. Laboratory evaluation revealed persistently low serum alkaline phosphatase (ALP) activity with otherwise normal bone metabolism markers. The patient's family history, which included a known ALPL gene mutation, ultimately led to the diagnosis of a rare metabolic bone disorder. Genetic testing confirmed the adult form of hypophosphatasia. This case highlights the importance of subtle biochemical findings and thorough family history in the diagnosis of rare conditions.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 7","pages":"297-301"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144795189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Fever, tetraparesis and confusion - neurological phenomena in influenza]. [发烧、四肢瘫痪和精神错乱——流感的神经学现象]。
Praxis Pub Date : 2025-07-01 DOI: 10.23785/PRAXIS.2025.07.009
Elena Pletzer, Katia Boggian, Matthias Arnold, Claudia Schrag
{"title":"[Fever, tetraparesis and confusion - neurological phenomena in influenza].","authors":"Elena Pletzer, Katia Boggian, Matthias Arnold, Claudia Schrag","doi":"10.23785/PRAXIS.2025.07.009","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.07.009","url":null,"abstract":"<p><strong>Introduction: </strong>In this case study, we present an unusual course of a 40-year-old patient with clinical signs of a viral infection with leading gastrointestinal symptoms. In the short term, he developed a progressive ascending sensorimotor tetraparesis with autonomic symptoms as well as qualitative disturbance of consciousness and the need for intensive medical care. Imaging revealed transverse myelitis and a diffusion disorder of the splenium (so-called CLOCC lesion). A diagnosis of \"mild encephalopathy with reversible splenial lesion (MERS)\" and \"longitudinally extensive transverse myelitis (LETM)\" was made. An influenza B infection was diagnosed as the causative disease. This is an immunologically triggered pathogenesis. Immunosuppressive therapy indicated.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 7","pages":"302-306"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144795190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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