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[Fever of unknown origin: A diagnostic challenge]. 原因不明的发热：诊断上的挑战。
Praxis Pub Date : 2025-06-01 DOI: 10.23785/PRAXIS.2025.06.009
Roman Zimmermann, Szilveszter Pekardi, Julia Zimmermann, Alptug Doganci, Annette Enzler-Tschudy, Alexander Kueres-Wiese
{"title":"[Fever of unknown origin: A diagnostic challenge].","authors":"Roman Zimmermann, Szilveszter Pekardi, Julia Zimmermann, Alptug Doganci, Annette Enzler-Tschudy, Alexander Kueres-Wiese","doi":"10.23785/PRAXIS.2025.06.009","DOIUrl":"10.23785/PRAXIS.2025.06.009","url":null,"abstract":"<p><strong>Introduction: </strong>Fever of unknown origin (FUO) presents a significant diagnostic challenge, particularly in young patients. A 25-year-old patient presents with persistent fever, with no clear cause identified through initial investigations. Stepwise advanced diagnostics ultimately lead to an unexpected diagnosis that significantly influences treatment. This case highlights the importance of a structured and interdisciplinary approach in the evaluation of FUO.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 6","pages":"253-256"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Sex and Gender Differences in Patients Undergoing Catheter Ablation for Supraventricular Tachyarrhythmias]. [室上性心动过速患者行导管消融的性别差异]。
Praxis Pub Date : 2025-06-01 DOI: 10.23785/PRAXIS.2025.06.005
Vera Quiriconi, Firat Duru, Corinna Brunckhorst
{"title":"[Sex and Gender Differences in Patients Undergoing Catheter Ablation for Supraventricular Tachyarrhythmias].","authors":"Vera Quiriconi, Firat Duru, Corinna Brunckhorst","doi":"10.23785/PRAXIS.2025.06.005","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.06.005","url":null,"abstract":"<p><strong>Introduction: </strong>This study assessed sex and gender differences in patients with atrial fibrillation (AF), atrial flutter (AFL), and other supraventricular tachycardias (SVT) undergoing catheter ablation. Four hundred patients (36.3 % female) with a median age of 62 were included. Significant gender differences were found in age at diagnosis and ablation of AF, with women with AF being diagnosed later. In the AF and AFL groups, fewer women were referred for EPS. Women experienced more dizziness in AF, more syncope in AFL, and more dyspnea in SVT. Ablation success was high and equal for both sexes. Awareness of these sex differences is crucial for establishing equal healthcare management.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 6","pages":"228-233"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Paraneoplastic limbic encephalitis - an important differential diagnosis in cases of unclear encephalopathy]. [副肿瘤边缘脑炎-不明脑病病例的重要鉴别诊断]。
Praxis Pub Date : 2025-06-01 DOI: 0.23785/PRAXIS.2025.06.006
Giulia Spotswood, Lukas Dürst, Thomas Fehr, Lita Rogalla von Bieberstein
{"title":"[Paraneoplastic limbic encephalitis - an important differential diagnosis in cases of unclear encephalopathy].","authors":"Giulia Spotswood, Lukas Dürst, Thomas Fehr, Lita Rogalla von Bieberstein","doi":"0.23785/PRAXIS.2025.06.006","DOIUrl":"https://doi.org/0.23785/PRAXIS.2025.06.006","url":null,"abstract":"<p><strong>Introduction: </strong>The diagnostics of autoimmune encephalitides have made significant progress with the recent discovery of numerous tumor-associated and non-tumor-associated autoantibodies targeting neuronal and glial cells. Nevertheless, physicians continue to face major diagnostic and therapeutic challenges posed by this complex disease. This review summarizes the key aspects of the clinical presentation, diagnostics, and therapy of the most common form of autoimmune encephalitis, limbic encephalitis, with a focus on the paraneoplastic forms.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 6","pages":"234-239"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The Hospital at Home care model in Switzerland - initial results from a pioneering clinic]. [瑞士的家庭医院护理模式——来自一家开创性诊所的初步结果]。
Praxis Pub Date : 2025-06-01 DOI: 10.23785/PRAXIS.2025.06.002
Caroline Schneider, Severin Pöchtrager, Tane Lammers, Thomas Bürkle, Christiane Eberhardt, Philipp Busche, Lukas Schöb, Daniel Krüerke, Markus Singer, Werner Vach, Friederike Johanna Schirin Thilo
{"title":"[The Hospital at Home care model in Switzerland - initial results from a pioneering clinic].","authors":"Caroline Schneider, Severin Pöchtrager, Tane Lammers, Thomas Bürkle, Christiane Eberhardt, Philipp Busche, Lukas Schöb, Daniel Krüerke, Markus Singer, Werner Vach, Friederike Johanna Schirin Thilo","doi":"10.23785/PRAXIS.2025.06.002","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.06.002","url":null,"abstract":"<p><strong>Introduction: </strong>Hospital at Home (HaH) is a form of care in which acutely ill patients are treated at home rather than in hospital. It is well established in many countries. In Switzerland, HaH is currently being piloted by various providers. The Arlesheim Hospital in the canton of Basel-Landschaft is one of these pioneers and has been offering HaH in its catchment area since January 2023. Referrals can be made by the emergency department, by general practitioners, specialists or by hospitals. This article provides an insight into how such a HaH programme works in practice and into the effects and opportunities that this new form of care offers. First results on safety of care, quality of care and satisfaction are presented.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 6","pages":"217-221"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Fatigue, performance deficits and snoring as early symptoms of systemic disease]. 【全身疾病的早期症状是疲劳、运动能力不足和打鼾】。
Praxis Pub Date : 2025-06-01 DOI: 10.23785/PRAXIS.2025.06.008
Luzia Maria Gruber, Peter Kurz
{"title":"[Fatigue, performance deficits and snoring as early symptoms of systemic disease].","authors":"Luzia Maria Gruber, Peter Kurz","doi":"10.23785/PRAXIS.2025.06.008","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.06.008","url":null,"abstract":"<p><strong>Introduction: </strong>A 68-year-old patient presented with a two-week history of fatigue, weakness, and sleep disturbances. This followed a curative prostatectomy due to cancer and an upper respiratory tract infection. Initially, obstructive sleep apnea (OSAS) was diagnosed. Several weeks later, new symptoms of dyspnea emerged, suggesting heart failure. Ultimately, AL-amyloidosis with cardiac involvement, associated with smoldering multiple myeloma, was diagnosed. Early consideration of a hematological malignancy, supported by immunofixation electrophoresis and closer monitoring, could have led to a quicker diagnosis and improved prognosis.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 6","pages":"247-252"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Asthma essentials for the practitioner]. 【哮喘治疗要点】。
Praxis Pub Date : 2025-06-01 DOI: 10.23785/PRAXIS.2025.06.003
Thomas Rothe
{"title":"[Asthma essentials for the practitioner].","authors":"Thomas Rothe","doi":"10.23785/PRAXIS.2025.06.003","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.06.003","url":null,"abstract":"<p><strong>Introduction: </strong>Good treatment options are now available, particularly for the more common forms of asthma with type 2 inflammation. Asthmatics should learn to assess their own asthma control. In the case of exacerbations that cannot be quickly controlled with a self-management plan, a consultation with spirometry and at least a check of the eosinophil count in the differential blood count is necessary. It makes sense for spirometry to be checked prior to an exacerbation, but also after OCS therapy. This is the only way to differentiate between asthma, asthma-COPD co-existence, and COPD.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 6","pages":"222-226"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Geschlechterspezifische Medizin – ein Grundpfeiler der personalisierten Behandlung. 性别特异性医学：个性化治疗的基本支柱。
Praxis Pub Date : 2025-06-01 DOI: 10.23785/PRAXIS.2025.06.004
Rubén Fuentes Artiles
{"title":"Geschlechterspezifische Medizin – ein Grundpfeiler der personalisierten Behandlung.","authors":"Rubén Fuentes Artiles","doi":"10.23785/PRAXIS.2025.06.004","DOIUrl":"10.23785/PRAXIS.2025.06.004","url":null,"abstract":"<p><strong>Introduction: </strong></p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 6","pages":"227"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Maple syrup urine disease decompensation - rare but life-threatening]. [枫糖浆尿失代偿-罕见但危及生命]。
Praxis Pub Date : 2025-06-01 DOI: 10.23785/PRAXIS.2025.06.010
Karin Vogt, Matthias Baumgartner, Katharina Timper
{"title":"[Maple syrup urine disease decompensation - rare but life-threatening].","authors":"Karin Vogt, Matthias Baumgartner, Katharina Timper","doi":"10.23785/PRAXIS.2025.06.010","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.06.010","url":null,"abstract":"<p><strong>Introduction: </strong>Maple syrup urine disease (MSUD) is a rare inherited metabolic disease. Breakdown of branched-chain amino acids (leucine, isoleucine, valine) is impaired or absent, which results in metabolite accumulation causing neurotoxicity. With strict therapy adherence (protein restricted MSUD-diet and amino acid supplementation), nearly normal plasma leucin levels can be achieved. However, therapy interruption or catabolic conditions (illness, operation, fasting) can rapidly lead to life-threatening metabolic decompensation. In this report we present the case of a 50 year-old woman who was referred to our hospital with impaired level of consciousness due to delayed recognition of MSUD decompensation. The aim is to increase awareness for this condition and repeat the central treatment aspects.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 6","pages":"257-260"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wie tief sollte der Blutdruck beim Diabetiker sein? 糖尿病患者的血压应该有多低？
Praxis Pub Date : 2025-06-01 DOI: 10.23785/PRAXIS.2025.06.001
Andrea Rosemann
{"title":"Wie tief sollte der Blutdruck beim Diabetiker sein?","authors":"Andrea Rosemann","doi":"10.23785/PRAXIS.2025.06.001","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.06.001","url":null,"abstract":"<p><strong>Introduction: </strong></p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 6","pages":"216"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Focus on the heart and psyche - an impressive case from the rehabilitation clinic]. [关注心灵和精神——来自康复诊所的一个令人印象深刻的案例]。
Praxis Pub Date : 2025-06-01 DOI: 10.23785/PRAXIS.2025.06.007
Kunigunde Pausch, Uwe Grommas, Roland von Känel, Anke Schneiders, Doris Straus, Gavin Brupbacher
{"title":"[Focus on the heart and psyche - an impressive case from the rehabilitation clinic].","authors":"Kunigunde Pausch, Uwe Grommas, Roland von Känel, Anke Schneiders, Doris Straus, Gavin Brupbacher","doi":"10.23785/PRAXIS.2025.06.007","DOIUrl":"10.23785/PRAXIS.2025.06.007","url":null,"abstract":"<p><strong>Introduction: </strong>Cardiovascular diseases rank among the leading causes of death worldwide. Patients with cardiovascular diseases often require lifelong follow-ups and medication. Psychological symptoms are prevalent in this population, and early recognition of such symptoms is crucial for improving the course of the cardiovascular disease. This case report presents the story of a patient with an aortic dissection whose diagnosis and necessary treatment were delayed. Subsequently, the patient experienced flashbacks, which consisted of negative experiences related to the cardiovascular disease and earlier traumatic life events. Successful treatment involved a combination of cardiac intervention, including aortic arch replacement, cardiac rehabilitation, and psychocardiological care during the rehabilitation phase.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 6","pages":"240-245"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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