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Schützt der Konsum von fettreichem Käse vor Demenz? 吃高脂肪奶酪能预防痴呆吗？
Praxis Pub Date : 2026-04-01 DOI: 10.23785/PRAXIS.2026.04.001
Andreas Nadig, Thomas Rosemann
{"title":"Schützt der Konsum von fettreichem Käse vor Demenz?","authors":"Andreas Nadig, Thomas Rosemann","doi":"10.23785/PRAXIS.2026.04.001","DOIUrl":"https://doi.org/10.23785/PRAXIS.2026.04.001","url":null,"abstract":"<p><strong>Introduction: </strong></p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 4","pages":"95"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Slowly progressive, non-traumatic swelling of the left ankle. What does this have to do with rice grains?] 左脚踝缓慢进行性非创伤性肿胀。这和米粒有什么关系？］
Praxis Pub Date : 2026-04-01 DOI: 10.23785/PRAXIS.2026.04.004
David Jutzi, Robert Escher, Gabriel Waldegg
{"title":"[Slowly progressive, non-traumatic swelling of the left ankle. What does this have to do with rice grains?]","authors":"David Jutzi, Robert Escher, Gabriel Waldegg","doi":"10.23785/PRAXIS.2026.04.004","DOIUrl":"https://doi.org/10.23785/PRAXIS.2026.04.004","url":null,"abstract":"<p><strong>Introduction: </strong>This case illustrates the diagnostic approach to chronic arthropathy or tendinopathy. Based on the most common causes, initial evaluation should primarily include imaging and rheumatological assessment. Depending on the results, patients may be managed in primary care or referred to an appropriate specialist. In this patient, extended investigations revealed tuberculous rice body tenosynovitis. After surgical treatment and nine months of antituberculous therapy, an excellent clinical outcome was achieved.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 4","pages":"107-110"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vorstellung unseres Redaktionsmitglieds Prof. Dr. med. Philipp Tarr. 介绍我们的编辑成员教授Dr. med。Philipp塔尔.
Praxis Pub Date : 2026-04-01
Dagmar Keller Lang
{"title":"Vorstellung unseres Redaktionsmitglieds Prof. Dr. med. Philipp Tarr.","authors":"Dagmar Keller Lang","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong></p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 4","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Amyotrophic lateral sclerosis (ALS): current perspectives and the Swiss ALS Registry]. [肌萎缩性侧索硬化症（ALS）：目前的观点和瑞士ALS登记]。
Praxis Pub Date : 2026-04-01 DOI: 10.23785/PRAXIS.2026.04.003
Sasha Mukhija, Franz Lehner, Hans H Jung
{"title":"[Amyotrophic lateral sclerosis (ALS): current perspectives and the Swiss ALS Registry].","authors":"Sasha Mukhija, Franz Lehner, Hans H Jung","doi":"10.23785/PRAXIS.2026.04.003","DOIUrl":"https://doi.org/10.23785/PRAXIS.2026.04.003","url":null,"abstract":"<p><strong>Introduction: </strong>Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease leading to muscle weakness, atrophy, and ultimately death. In addition to mutations in ALS-related genes, environmental and lifestyle factors may increase disease risk. Diagnosis is based on clinical evaluation, supplemented by electroneuromyography, imaging, and molecular genetic testing. No curative therapy exists, but Riluzole and Edaravone can slow progression, and genetic therapies offer promising perspectives in certain genetically determined forms. In practice, diagnosis is often delayed. The Swiss ALS Registry collects comprehensive data on environmental, lifestyle, clinical, genetic, and biomarker factors, aiming to improve understanding of risk, disease progression, and therapeutic approaches.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 4","pages":"100-106"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Orbital pathology, not always caused by endocrine factors]. 眼眶病理，并不总是由内分泌因素引起。
Praxis Pub Date : 2026-04-01 DOI: 10.23785/PRAXIS.2026.04.005
Pascale Hösli, Marino Quarella Quarella, Raphael Jeker, Giatgen Spinas, Thomas Neumann, Michael Brändle
{"title":"[Orbital pathology, not always caused by endocrine factors].","authors":"Pascale Hösli, Marino Quarella Quarella, Raphael Jeker, Giatgen Spinas, Thomas Neumann, Michael Brändle","doi":"10.23785/PRAXIS.2026.04.005","DOIUrl":"https://doi.org/10.23785/PRAXIS.2026.04.005","url":null,"abstract":"<p><strong>Introduction: </strong>Not all cases of Exophthalmos are related to Graves' disease. Normal thyroid function test results should prompt extended differential diagnostics. IgG4-related disease (IgG4-RD) mimics various inflammatory, infectious, or neoplastic conditions. Diagnosis requires integration of clinical, laboratory, imaging, and histopathological findings. Early glucocorticoid therapy can reduce organ involvement and improve patient outcomes.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 4","pages":"111-114"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[When the brain starves: A life-threatening neurological complication following bariatric surgery]. [当大脑饥饿：减肥手术后危及生命的神经系统并发症]。
Praxis Pub Date : 2026-04-01 DOI: 10.23785/PRAXIS.2026.04.007
Angela Mettler, Tomas Klail, Martin Müller, Elisa Ferrazzini
{"title":"[When the brain starves: A life-threatening neurological complication following bariatric surgery].","authors":"Angela Mettler, Tomas Klail, Martin Müller, Elisa Ferrazzini","doi":"10.23785/PRAXIS.2026.04.007","DOIUrl":"https://doi.org/10.23785/PRAXIS.2026.04.007","url":null,"abstract":"<p><strong>Introduction: </strong>In this case report, we describe a 31-year-old female patient who presented with intermittent diplopia, progressive gait instability, dizziness and forgetfulness. Clinical examination revealed decreased level of consciousness (Glasgow Coma Scale score of 14), horizontal and vertical gaze-evoked nystagmus, bilateral abducens nerve palsy, and severe truncal and gait ataxia. Laboratory analyses did not reveal any diagnostic findings. Brain magnetic resonance imaging (MRI) showed bilateral FLAIR-hyperintensities in the dorsomedial thal-amus, mammillary bodies, and around the third ventricle extending into the quadrigeminal plate of the midbrain, findings indicative of Wernicke's encephalopathy. Given the patient's history of sleeve gastrectomy performed three months earlier, and the presumed thiamine (vitamin B1) deficiency due to malabsorption, reduced nutritional intake, and lack of micro-nutrient supplementation, the diagnosis of Wernicke's encephalopathy was established and high-dose intravenous thiamine therapy was initiated.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 4","pages":"119-122"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Oxygen in medicine - basics, applications and risks]. [医学中的氧气——基础、应用和风险]。
Praxis Pub Date : 2026-04-01 DOI: 10.23785/PRAXIS.2026.04.002
Daniel Franzen, Ingo Hülter, Alexander Turk
{"title":"[Oxygen in medicine - basics, applications and risks].","authors":"Daniel Franzen, Ingo Hülter, Alexander Turk","doi":"10.23785/PRAXIS.2026.04.002","DOIUrl":"https://doi.org/10.23785/PRAXIS.2026.04.002","url":null,"abstract":"<p><strong>Introduction: </strong>Oxygen is a central component in the treatment of acute and chronic diseases associated with hypoxemia. Nevertheless, in everyday clinical practice it is often administered reflexively, even when documented or clearly suspected hypoxemia - the most important prerequisite for appropriate oxygen therapy - is absent. Dyspnea alone is not an indication, as patients with breathlessness but without hypoxaemia ge-nerally do not benefit from oxygen administration. Controlled titration with clearly defined target ranges is essential in order to avoid risks such as hypercapnia, coronary and cerebral vasoconstriction, oxygen toxicity, absorption atelectasis, or even increased mortality. Long-term oxygen therapy remains a prognostically relevant intervention in patients with stable chronic hypoxaemia. This article summarizes the physiological principles, indications, risks, technical delivery systems, and reimbursement considerations relevant to primary care practice.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 4","pages":"96-99"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Chronic abdominal pain in elderly patient]. [老年慢性腹痛患者]。
Praxis Pub Date : 2026-04-01 DOI: 10.23785/PRAXIS.2026.04.006
Silvio Trepp, Lukas Zimmerli
{"title":"[Chronic abdominal pain in elderly patient].","authors":"Silvio Trepp, Lukas Zimmerli","doi":"10.23785/PRAXIS.2026.04.006","DOIUrl":"https://doi.org/10.23785/PRAXIS.2026.04.006","url":null,"abstract":"<p><strong>Introduction: </strong>A 75-year-old female patient with autosomal-dominant polycystic kidney disease and a history of kidney transplantation presented to the emergency department with dysuria, chills and abdominal pain. A detailed review of her medical history revealed that her acute pyelonephritis was masking a chronic abdominal pain issue accompanied by significant bilirubinemia. MRCP showed a complete cystic transformation of the left liver lobe and liver fibrosis. Consequently, the diagnosis of Caroli syndrome, a rare cystic liver disease with fibrosis, was established despite her advanced age.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 4","pages":"115-118"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A malignant cause of metabolic decompensation]. [代谢失代偿的恶性原因]。
Praxis Pub Date : 2026-03-01 DOI: 10.23785/PRAXIS.2026.03.005
Anja Forrer, Mattia Giarrusso, Rahel Wright, Anja Rückert, Anna-Elisabeth Minder, Lars Christian Huber, Corina Omlin
{"title":"[A malignant cause of metabolic decompensation].","authors":"Anja Forrer, Mattia Giarrusso, Rahel Wright, Anja Rückert, Anna-Elisabeth Minder, Lars Christian Huber, Corina Omlin","doi":"10.23785/PRAXIS.2026.03.005","DOIUrl":"https://doi.org/10.23785/PRAXIS.2026.03.005","url":null,"abstract":"<p><strong>Introduction: </strong>With wide-spread use of computed tomography and magnetic resonance imaging studies, numbers of incidentally found adrenal tumors are rising. All adrenal tumors should be evaluated for dignity and hormonal activity. In our case report, we present a patient with a rare, but highly aggressive adrenal malignoma.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 3","pages":"83-86"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147723540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Oxygen therapy in acute medicine]. [急症医学中的氧疗]。
Praxis Pub Date : 2026-03-01 DOI: 10.23785/PRAXIS.2026.03.003
Michael Bleiker, Maurice Roeder
{"title":"[Oxygen therapy in acute medicine].","authors":"Michael Bleiker, Maurice Roeder","doi":"10.23785/PRAXIS.2026.03.003","DOIUrl":"10.23785/PRAXIS.2026.03.003","url":null,"abstract":"<p><strong>Introduction: </strong>Oxygen therapy is a cornerstone of acute medical care but requires careful indication and monitoring. This mini-review outlines historical aspects, physiological principles, and the risks associated with hypoxemia and hyperoxia. Current target ranges for oxygen saturation are presented, including patient-specific considerations in those at risk of hypercapnia. Emphasis is placed on conservative oxygen administration. Common oxygen delivery systems and their role in acute care settings are also reviewed.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 3","pages":"73-77"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147723463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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