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[Immobilizing back pain in an elderly patient: Differential diagnostic considerations and diagnosis]. [老年患者固定性背痛：鉴别诊断考虑和诊断]。
Praxis Pub Date : 2026-08-01 DOI: 10.23785/PRAXIS.2026.08.006
Nicole Schmid, Michael Osthoff, Dimitri Gassmann
{"title":"[Immobilizing back pain in an elderly patient: Differential diagnostic considerations and diagnosis].","authors":"Nicole Schmid, Michael Osthoff, Dimitri Gassmann","doi":"10.23785/PRAXIS.2026.08.006","DOIUrl":"10.23785/PRAXIS.2026.08.006","url":null,"abstract":"<p><strong>Introduction: </strong>A 77-year-old patient presents with acute back pain. Due to elevated CRP and other lab abnormalities, bacterial spondylodiscitis is initially suspected, and blood cultures are obtained early. However, a biopsy reveals uric acid crystals and cultures remain negative, leading to the diagnosis of gout spondylodiscitis. Treatment includes renal-adjusted anti-inflammatory therapy, urate-lowering therapy and flare prophylaxis.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 8","pages":"240-243"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148906786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Fulminant blood sugar increase - a rare but life-threatening course]. [暴发性血糖升高——一种罕见但危及生命的过程]。
Praxis Pub Date : 2026-08-01 DOI: 10.23785/PRAXIS.2026.08.007
Moritz Sigg, Stefan Diem, Stefan Bilz
{"title":"[Fulminant blood sugar increase - a rare but life-threatening course].","authors":"Moritz Sigg, Stefan Diem, Stefan Bilz","doi":"10.23785/PRAXIS.2026.08.007","DOIUrl":"10.23785/PRAXIS.2026.08.007","url":null,"abstract":"<p><strong>Introduction: </strong>A 71-year-old patient with known metastatic melanoma undergoing treatment with the immune checkpoint inhibitors Ipilimumab/Nivolumab presented with a rapid deterioration in general condition over the past 24 hours. Approximately three weeks after starting ICI-the-rapy, thyroiditis was diagnosed, which progressed to a substitution-requiring hypothyroidism. Currently, laboratory tests revealed severe keto-acidosis with acute blood sugar derangement (51 mmol/l) despite only a mildly elevated HbA1c (6.3 %). We hereby diagnosed fulminant ICI- associated type 1 diabetes mellitus. Symptoms improved under insulin therapy.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 8","pages":"244-246"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148906678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sexuelle Nebenwirkung unter Finasterid – grösstenteils Nocebo? 非那雄胺的性副作用——主要是诺西波？
Praxis Pub Date : 2026-07-01 DOI: 10.23785/PRAXIS.2026.07.002
Thomas Rosemann
{"title":"Sexuelle Nebenwirkung unter Finasterid – grösstenteils Nocebo?","authors":"Thomas Rosemann","doi":"10.23785/PRAXIS.2026.07.002","DOIUrl":"10.23785/PRAXIS.2026.07.002","url":null,"abstract":"","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 7","pages":"184"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148723711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Rapid progression of neurological symptoms in an adult]. [成人神经症状的迅速发展]。
Praxis Pub Date : 2026-07-01 DOI: 10.23785/PRAXIS.2026.07.004
Lukas Hänel, Christoph Hauser
{"title":"[Rapid progression of neurological symptoms in an adult].","authors":"Lukas Hänel, Christoph Hauser","doi":"10.23785/PRAXIS.2026.07.004","DOIUrl":"10.23785/PRAXIS.2026.07.004","url":null,"abstract":"<p><strong>Introduction: </strong>Measles is a highly contagious viral disease whose incidence has declined significantly since the introduction of vaccination in the mid-1970s. However, local outbreaks continue to occur due to insufficient vaccination rates. Adults are at higher risk of complications. The present case of a patient with acute post-infectious measles encephalitis despite a history of presumed measles vaccination underscores the critical importance of vaccination as a preventive measure. In everyday general practice, there is an opportunity to identify individuals who have not been vaccinated against measles and to guide them toward achieving full vaccination coverage.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 7","pages":"194-196"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148726614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[An unusual cause for unilateral eye pain with double vision]. [单侧眼睛疼痛伴复视的不寻常原因]。
Praxis Pub Date : 2026-07-01 DOI: 10.23785/PRAXIS.2026.07.006
Julia Nungesser, Christoph Hemmeler
{"title":"[An unusual cause for unilateral eye pain with double vision].","authors":"Julia Nungesser, Christoph Hemmeler","doi":"10.23785/PRAXIS.2026.07.006","DOIUrl":"10.23785/PRAXIS.2026.07.006","url":null,"abstract":"<p><strong>Introduction: </strong>A 48-year-old man was diagnosed with IgG4-related disease (IgG4-RD) during an evaluation for exophthalmos and unexplained pain on the left side of his face. The diagnosis was made by ruling out all other possible conditions and was based on histopathological findings. After initiating immunosuppressive therapy with corticosteroids (GC), most of the symptoms resolved. As the GC-dose was gradually reduced, a relapse occurred, leading to two courses of Rituximab. Reflecting the success of the therapy, long-term follow-up revealed a marked radiological reduction in the retrobulbar mass and a significant clinical improvement in pain.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 7","pages":"200-205"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148723124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Management of chronic wounds in general practice]. [普通医学中慢性伤口的处理]。
Praxis Pub Date : 2026-07-01 DOI: 10.23785/PRAXIS.2026.07.003
Severin Läuchli, Martin Berli, Michaela Kaiser, Susanne Bolt-Kobler, Anke Buschor, Merlin Guggenheim, Sonja Haverkampf, Melina Kälin, Claudia Keller, Bettina Matzinger, Michela Tavernini
{"title":"[Management of chronic wounds in general practice].","authors":"Severin Läuchli, Martin Berli, Michaela Kaiser, Susanne Bolt-Kobler, Anke Buschor, Merlin Guggenheim, Sonja Haverkampf, Melina Kälin, Claudia Keller, Bettina Matzinger, Michela Tavernini","doi":"10.23785/PRAXIS.2026.07.003","DOIUrl":"10.23785/PRAXIS.2026.07.003","url":null,"abstract":"<p><strong>Introduction: </strong>Chronic wounds remain a major problem despite advances in wound care. Around 1 % of the population is affected and experiences a significant reduction in quality of life as a result. General practices are often the first port of call for impaired wound healing and chronic wounds. They are responsible for the comprehensive assessment and management of wounds and their underlying causes. This article summarises the current state of knowledge and recommendations, taking into account a cost-effective approach.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 7","pages":"185-193"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148722620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Drug-induced liver injury (DILI)]. 药物性肝损伤（DILI）。
Praxis Pub Date : 2026-07-01 DOI: 10.23785/PRAXIS.2026.07.007
Manuel Zingg, Ruth Greber, Giacomo Faleschini, Roman Hari
{"title":"[Drug-induced liver injury (DILI)].","authors":"Manuel Zingg, Ruth Greber, Giacomo Faleschini, Roman Hari","doi":"10.23785/PRAXIS.2026.07.007","DOIUrl":"10.23785/PRAXIS.2026.07.007","url":null,"abstract":"<p><strong>Introduction: </strong>We present a case of recurrent international normalised ratio (INR) derailment during treatment with phenprocoumon for sinus vein thrombosis. During the course of the illness, the patient developed signs of bleeding, such as epistaxis, gross haematuria and vaginal bleeding, as well as elevated liver enzyme levels. This ultimately led to hospitalisation, where a diagnosis of acute hepatitis associated with drug-induced liver injury (DILI) was made. Following the discontinuation of phenprocoumon and a switch to apixaban for anticoagulation therapy, as well as repeated administration of vitamin K, the patient's condition stabilised. The laboratory findings, liver biopsy and clinical course are most consistent with toxic hepatitis caused by phenprocoumon.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 7","pages":"206-209"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148723835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[On the wrong track: Misled by the patient history]. 【误入歧途：被病史误导】。
Praxis Pub Date : 2026-07-01 DOI: 10.23785/PRAXIS.2026.07.005
Fabienne Adler, Adrian Schmid, Esther Gerrits, Urs Karrer
{"title":"[On the wrong track: Misled by the patient history].","authors":"Fabienne Adler, Adrian Schmid, Esther Gerrits, Urs Karrer","doi":"10.23785/PRAXIS.2026.07.005","DOIUrl":"10.23785/PRAXIS.2026.07.005","url":null,"abstract":"<p><strong>Introduction: </strong>Case report of a young immunocompetent patient presenting with aseptic meningitis due to varicella-zoster virus (VZV) infection. Reactivation of VZV manifesting as meningitis is an uncommon clinical presentation compared to herpes zoster. While a concomitant vesicular rash is frequently observed, it may be absent in some cases. With antiviral therapy initiated promptly, the clinical outcome is generally favorable.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 7","pages":"197-199"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148726882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lipidsenkung nach Koronarstent – wie strikt soll sie sein? 冠状动脉支架后脂质下降——有多严重？
Praxis Pub Date : 2026-07-01 DOI: 10.23785/PRAXIS.2026.07.001
Anna Saugy, Thomas Rosemann
{"title":"Lipidsenkung nach Koronarstent – wie strikt soll sie sein?","authors":"Anna Saugy, Thomas Rosemann","doi":"10.23785/PRAXIS.2026.07.001","DOIUrl":"10.23785/PRAXIS.2026.07.001","url":null,"abstract":"<p><strong>Introduction: </strong></p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 7","pages":"183"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148724756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Postoperative serotonin syndrome in a patient with attention-deficit/hyperactivity disorder and treatment-resistant depression]. [术后血清素综合征患者的注意缺陷/多动障碍和治疗难治性抑郁症]。
Praxis Pub Date : 2026-06-01 DOI: 10.23785/PRAXIS.2026.06.007
Michael Nii Aboe Aboe, Natalia Wege
{"title":"[Postoperative serotonin syndrome in a patient with attention-deficit/hyperactivity disorder and treatment-resistant depression].","authors":"Michael Nii Aboe Aboe, Natalia Wege","doi":"10.23785/PRAXIS.2026.06.007","DOIUrl":"10.23785/PRAXIS.2026.06.007","url":null,"abstract":"<p><strong>Introduction: </strong>A patient diagnosed with attention-deficit/hyperactivity disorder (ADHD) and treatment-resistant depression (TRD) developed postoperative serotonin syndrome after exposure to venlafaxine, opioids, stimulants, and cannabis. The Hunter criteria facilitated the diagnosis; discontinuation of serotonergic agents and supportive measures led to reversal.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"115 6","pages":"180-182"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148318129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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