Praxis最新文献

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[Abdominal pain out of proportion by a young, healthy patient]. [年轻健康病人的腹部疼痛不成比例]。
Praxis Pub Date : 2025-05-01 DOI: 10.23785/PRAXIS.2025.05.009
Sabine Fischbacher, Larissa C Vines, Bruno Minotti
{"title":"[Abdominal pain out of proportion by a young, healthy patient].","authors":"Sabine Fischbacher, Larissa C Vines, Bruno Minotti","doi":"10.23785/PRAXIS.2025.05.009","DOIUrl":"10.23785/PRAXIS.2025.05.009","url":null,"abstract":"<p><strong>Introduction: </strong>We report on a 29-year-old patient with highly intense, acute abdominal pain of idiopathic origin (out of proportion), admitted to the emergency department with suspected appendicitis. An ultrasound revealed signs of bowel obstruction, and due to persistent pain despite intravenous morphine analgesia, a computed tomography was performed, revealing a closed-loop obstruction. The patient underwent laparoscopy, where an omental adhesion was identified and surgically resolved. The postoperative course was uneventful. This potentially dangerous diagnosis should be considered even in healthy patients without prior surgeries. Keywords: Acute abdomen, abdominal pain, intestinal obstruction, ileus, closed loop obstruction, emergency medicine.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 5","pages":"209-211"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144161568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The dark side of the sunshine vitamin]. [阳光维生素的阴暗面]。
Praxis Pub Date : 2025-05-01 DOI: 10.23785/PRAXIS.2025.05.006
Judith Everts-Graber
{"title":"[The dark side of the sunshine vitamin].","authors":"Judith Everts-Graber","doi":"10.23785/PRAXIS.2025.05.006","DOIUrl":"10.23785/PRAXIS.2025.05.006","url":null,"abstract":"<p><strong>Introduction: </strong></p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 5","pages":"198"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144161579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Large retroperitoneal mass in a young patient]. [年轻患者腹膜后大肿块]。
Praxis Pub Date : 2025-05-01 DOI: 10.23785/PRAXIS.2025.05.010
Kilian Meier, Daniela Weiler
{"title":"[Large retroperitoneal mass in a young patient].","authors":"Kilian Meier, Daniela Weiler","doi":"10.23785/PRAXIS.2025.05.010","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.05.010","url":null,"abstract":"<p><strong>Introduction: </strong>This medical case report describes the diagnosis and treatment of a 24-year-old man with a germ cell tumor. The patient presented to the emergency practice with a palpable mass in the left upper abdomen that had been present for three weeks, without any additional symptoms. Bedside ultrasonography revealed an inhomogeneous tumor in the retroperitoneum. Further ultrasound examination of the abdomen and testicle identified a possible primary tumor in the left testicle, which was classified as a tumor with non-seminoma parts based on laboratory findings with markedly elevated Beta-HCG and AFP levels. Additionally a primary orchidectomy followed for definitive diagnosis. The patient underwent chemotherapy with four cycles of cisplatin, etoposide, and bleomycin, which was well-tolerated. After the removal of the remaining retroperitoneal mass, complete remission was achieved. This case highlights the importance of comprehensive diagnostics and interdisciplinary collaboration in the treatment of germ cell tumors, as well as the critical role of ultrasound in both emergency and primary care settings. With early diagnosis and appropriate therapy, patients with these tumors have a very high survival rate despite the metastasis. Keywords: Germ cell tumour, retroperitoneal mass, beta-HCG and AFP, orchiectomy, chemotherapy.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 5","pages":"212-214"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144161516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Polymyalgia rheumatica and giant cell arteritis: two manifestations of the same disease?] 风湿性多肌痛与巨细胞动脉炎:同一疾病的两种表现?]
Praxis Pub Date : 2025-05-01 DOI: 10.23785/PRAXIS.2025.05.003
Oliver Pelikan, Katharina Rose, Christof Iking-Konert
{"title":"[Polymyalgia rheumatica and giant cell arteritis: two manifestations of the same disease?]","authors":"Oliver Pelikan, Katharina Rose, Christof Iking-Konert","doi":"10.23785/PRAXIS.2025.05.003","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.05.003","url":null,"abstract":"<p><strong>Introduction: </strong>Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are associated conditions that typically affect older patients, usually over the age of 50. Their clinical presentations often overlap, and the two can even transition into one another. Increasingly, they are viewed not as distinct diseases but as manifestations of a single disease spectrum. Common symptoms include shoulder pain, headaches, and visual disturbances. Diagnosis relies on imaging and inflammatory markers. Both conditions are initially treated with glucocorticoids, increasingly complemented by IL-6 inhibitors or methotrexate. New therapeutic approaches such as JAK inhibitors are currently in development.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 5","pages":"193-197"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144161559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Current diagnostics and therapy in acute rhinosinusitis]. 急性鼻窦炎的诊断和治疗现状
Praxis Pub Date : 2025-05-01 DOI: 10.23785/PRAXIS.2025.05.004
Francesca Parisi, Lukas Horvath
{"title":"[Current diagnostics and therapy in acute rhinosinusitis].","authors":"Francesca Parisi, Lukas Horvath","doi":"10.23785/PRAXIS.2025.05.004","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.05.004","url":null,"abstract":"<p><strong>Introduction: </strong>Acute rhinosinusitis (ARS) is one of the most common infectious diseases found the in the outpatient clinics. In order to avoid overuse of diagnostic tools and over-treatment, knowledge of its etiology is key. The objective of this paper is to present the current classification of ARS, its management recommendation and indications for antibiotic treatment as well as to identify potential complications. A review of the current literature for ARS was performed, especially of the two most significant position papers (EPOS 2020, ICARS-RS-2021, AAO-HNSF, AWMF-S2k-Leitlinie). The past years, a differentiated view on ARS and its classification has evolved. ARS is mainly an inflammatory disease triggered by viral infection while a minority develops into a bacterial infection. The diagnosis is mainly clinical and most cases are self-resolving with symptomatic treatment.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 5","pages":"188-192"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144161571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[What happens if you deliberately overdose on vitamin D?] 如果你故意过量服用维生素D会发生什么?]
Praxis Pub Date : 2025-05-01 DOI: 10.23785/PRAXIS.2025.05.007
Debora Meier, Katja Weiss, Thomas Rosemann, Beat Knechtle
{"title":"[What happens if you deliberately overdose on vitamin D?]","authors":"Debora Meier, Katja Weiss, Thomas Rosemann, Beat Knechtle","doi":"10.23785/PRAXIS.2025.05.007","DOIUrl":"10.23785/PRAXIS.2025.05.007","url":null,"abstract":"<p><strong>Introduction: </strong>About 30 % of the Swiss population regularly takes dietary supplements, whereas only 22 % of them have a medical reason to do so. We describe a case of a woman with multiple sclerosis and her partner, who has a rare metabolic disorder. Due to a lack of conventional treatment options perceived by the patient, they started a high-dose vitamin D supplementation. While the man only developed a subclinical vitamin D intoxication, the woman was hospitalized due to a severe vitamin-D-induced hypercalcemia.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 5","pages":"199-204"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144161581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Monotherapy with DOACs for patients with atrial fibrillation and stable coronary heart disease associated with lower risk than dual antithrombotic therapy]. [DOACs单药治疗房颤合并稳定型冠心病患者风险低于双药抗栓治疗]。
Praxis Pub Date : 2025-05-01 DOI: 10.23785/PRAXIS.2025.05.001
Michael Lütolf, Thomas Rosemann
{"title":"[Monotherapy with DOACs for patients with atrial fibrillation and stable coronary heart disease associated with lower risk than dual antithrombotic therapy].","authors":"Michael Lütolf, Thomas Rosemann","doi":"10.23785/PRAXIS.2025.05.001","DOIUrl":"10.23785/PRAXIS.2025.05.001","url":null,"abstract":"<p><strong>Introduction: </strong></p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 5","pages":"171"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144161520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Antibiotic Prophylaxis in Gastrointestinal Endoscopy]. [胃肠道内窥镜中的抗生素预防]。
Praxis Pub Date : 2025-04-01 DOI: 10.23785/PRAXIS.2025.04.003
Michael Manz, Stefan Kuster, Matthias Greutmann, Remus Frei
{"title":"[Antibiotic Prophylaxis in Gastrointestinal Endoscopy].","authors":"Michael Manz, Stefan Kuster, Matthias Greutmann, Remus Frei","doi":"10.23785/PRAXIS.2025.04.003","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.04.003","url":null,"abstract":"<p><strong>Introduction: </strong>The need for antibiotic prophylaxis for endoscopic procedures, especially in the gastrointestinal tract, has long been a matter of debate. In recent years, the lack of randomized trials supporting a benefit of antibiotic prophylaxis, the very low incidence of infective endocarditis after endoscopic procedures and the potential adverse reactions of antibiotics have led to a more restricted use of antibiotic prophylaxis. The aim of this expert opinion statement is to provide an overview of current evidence and to propose a pragmatic approach to the use of antibiotic prophylaxis for endoscopic procedures in areas where clear evidence is lacking.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 4","pages":"137-143"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144021976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Takotsubo syndrome caused by gunshot - a bullet missed the heart but still hits it]. [由枪击引起的Takotsubo综合征——子弹没有击中心脏,但仍然击中了心脏]。
Praxis Pub Date : 2025-04-01 DOI: 10.23785/PRAXIS.2025.04.007
Martina Oslayová, Christoph Gräni, Christian Muster
{"title":"[Takotsubo syndrome caused by gunshot - a bullet missed the heart but still hits it].","authors":"Martina Oslayová, Christoph Gräni, Christian Muster","doi":"10.23785/PRAXIS.2025.04.007","DOIUrl":"10.23785/PRAXIS.2025.04.007","url":null,"abstract":"<p><strong>Introduction: </strong>In our case, the rifle bullet fortunately did not hit the patient. Nevertheless, the incident was a very serious emotional event for the patient. Due to the release of stress hormones, the incident had an indirect and potentially fatal effect on the heart. A takotsubo syndrome emerged with typical chest pain, repolarization abnormalities and elevation of cardiac biomarkers. The morphology was atypical, showing mid-ventricular wall motion abnormalities. In our case, a previous episode of takotsubo syndrome can be suspected. Fortunately, the outcome was benign and the systolic LVEF normalized after 3 months of heart failure therapy. The severe complications associated with LVOT obstruction did not occur. This is not the first case report of a takotsubo syndrome after a gunshot, but it is the first without a direct effect of the bullet.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 4","pages":"155-158"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Food intolerances: more often suspected than confirmed]. [食物不耐受:更多的是怀疑而不是证实]。
Praxis Pub Date : 2025-04-01 DOI: 10.23785/PRAXIS.2025.04.004
Barbara Ballmer-Weber, Claudia Krieger-Grübel
{"title":"[Food intolerances: more often suspected than confirmed].","authors":"Barbara Ballmer-Weber, Claudia Krieger-Grübel","doi":"10.23785/PRAXIS.2025.04.004","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.04.004","url":null,"abstract":"<p><strong>Introduction: </strong>The perception of food intolerances is widespread, leading to unnecessary dietary restrictions and anxiety, particularly in patients with irritable bowel syndrome. Many self-diagnosed intolerances lack scientific evidence and are often used to explain chronic symptoms. Accurate diagnosis and evidence-based dietary recommendations are crucial to maintaining quality of life and preventing malnutrition. This review explores common food intolerances, including histamine intolerance, additive sensitivity, FODMAP-related issues, and non-celiac wheat sensitivity, providing an evidence-based perspective on their diagnosis and management.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 4","pages":"144-148"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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