[Polymyalgia rheumatica and giant cell arteritis: two manifestations of the same disease?]

Q4 Medicine
Praxis Pub Date : 2025-05-01 DOI:10.23785/PRAXIS.2025.05.003
Oliver Pelikan, Katharina Rose, Christof Iking-Konert
{"title":"[Polymyalgia rheumatica and giant cell arteritis: two manifestations of the same disease?]","authors":"Oliver Pelikan, Katharina Rose, Christof Iking-Konert","doi":"10.23785/PRAXIS.2025.05.003","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are associated conditions that typically affect older patients, usually over the age of 50. Their clinical presentations often overlap, and the two can even transition into one another. Increasingly, they are viewed not as distinct diseases but as manifestations of a single disease spectrum. Common symptoms include shoulder pain, headaches, and visual disturbances. Diagnosis relies on imaging and inflammatory markers. Both conditions are initially treated with glucocorticoids, increasingly complemented by IL-6 inhibitors or methotrexate. New therapeutic approaches such as JAK inhibitors are currently in development.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 5","pages":"193-197"},"PeriodicalIF":0.0000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Praxis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23785/PRAXIS.2025.05.003","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

Abstract

Introduction: Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are associated conditions that typically affect older patients, usually over the age of 50. Their clinical presentations often overlap, and the two can even transition into one another. Increasingly, they are viewed not as distinct diseases but as manifestations of a single disease spectrum. Common symptoms include shoulder pain, headaches, and visual disturbances. Diagnosis relies on imaging and inflammatory markers. Both conditions are initially treated with glucocorticoids, increasingly complemented by IL-6 inhibitors or methotrexate. New therapeutic approaches such as JAK inhibitors are currently in development.

风湿性多肌痛与巨细胞动脉炎:同一疾病的两种表现?]
多肌痛风湿病(PMR)和巨细胞动脉炎(GCA)是典型的影响老年患者的相关疾病,通常超过50岁。他们的临床表现经常重叠,两者甚至可以相互过渡。它们越来越不被视为不同的疾病,而被视为单一疾病谱系的表现。常见症状包括肩痛、头痛和视力障碍。诊断依赖于影像学和炎症标志物。这两种情况最初都用糖皮质激素治疗,逐渐辅以IL-6抑制剂或甲氨蝶呤。新的治疗方法,如JAK抑制剂目前正在开发中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Praxis
Praxis Medicine-Medicine (all)
CiteScore
0.40
自引率
0.00%
发文量
146
审稿时长
12 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信