Phytochemistry Letters最新文献

{"title":"Effect of UV-B radiation on photosynthesis based flavonoid synthesis in daylily leaves","authors":"Shuzhi Wang ,&nbsp;Shijie Zhang ,&nbsp;Xiang Liu ,&nbsp;Lu Bai ,&nbsp;Qiaoping Qin","doi":"10.1016/j.phytol.2024.06.005","DOIUrl":"https://doi.org/10.1016/j.phytol.2024.06.005","url":null,"abstract":"<div><p>In order to assess the impact of UV-B radiation on flavonoid compound levels in 'Stella de Oro' daylily leaves, three distinct treatment groups were established: a control group (CK) devoid of UV-B exposure, a low-dose UV-B group (L, 10 μw/cm²), and a high-dose UV-B group (H, 20 μw/cm²). Throughout the UV-B exposure period, parameters including leaf gas exchange, dry weight ratio, and flavonoid compound content were monitored. Following the UV-B treatment, there was a notable increase in the net photosynthesis rate (<em>Pn</em>) by 72 %, stomatal conductance (<em>Gs</em>) by 46 %, transpiration rate (<em>Tr</em>) by 42 %, and water use efficiency (<em>WUE</em>) by 21 %. Moreover, there was a notable increase in the total content of rutin, myricetin, and quercetin in the leaves by 110 %, 55 %, and 47 % respectively. The observed changes in leaf dry weight ratio under UV-B exposure in group H were consistent with the alterations in flavonoid compound levels in the leaves. Based on the results, PCA analysis indicated a significant correlation between <em>WUE</em> and flavonoids content, possibly related with the combined effect of <em>Pn</em> and <em>Tr</em>.</p></div>","PeriodicalId":20408,"journal":{"name":"Phytochemistry Letters","volume":"62 ","pages":"Pages 24-33"},"PeriodicalIF":1.3,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141482059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"α-pyrone derivatives from the endophytic Fusarium sp. L33 isolated from Dioscorea opposita","authors":"Ruo-Dan Tian ,&nbsp;Meng-Ke Sheng ,&nbsp;Ying-Fei Zhao ,&nbsp;Chun-Nan Wen ,&nbsp;Miao Liu ,&nbsp;Bing-Ji Ma","doi":"10.1016/j.phytol.2024.06.002","DOIUrl":"https://doi.org/10.1016/j.phytol.2024.06.002","url":null,"abstract":"<div><p>Two new <em>α</em>-pyrone derivatives, fusaripyrones C and D (<strong>1</strong> and <strong>2</strong>), along with six known compounds, namely phomapyrone C (<strong>3</strong>), fusarilactone A (<strong>4</strong>), pleospyrone D (<strong>5</strong>), 5-hydroxy-7-(2′-hydroxypropyl)-2-methyl-chromone (<strong>6</strong>), phenylacetic acid (<strong>7</strong>), and p-hydroxyphenylacetic acid (<strong>8</strong>) were isolated from <em>Fusarium</em> sp. L33, an endophytic fungus isolated from the leaves of <em>Dioscorea opposita</em>. Their structures were elucidated by NMR spectra, HRESIMS, optical rotation experiments and single-crystal X-ray diffraction analysis. Compounds <strong>2</strong>, <strong>3</strong>, and <strong>6</strong> were evaluated for their cytotoxic activity against five selected human tumor cell lines.</p></div>","PeriodicalId":20408,"journal":{"name":"Phytochemistry Letters","volume":"62 ","pages":"Pages 14-17"},"PeriodicalIF":1.7,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141424394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Healing effect of medicinal plant extracts in Northeast Brazil: A systematic review on phytochemistry and preclinical studies","authors":"Cauê Barbosa Coelho ,&nbsp;Cristiane dos Santos Cerqueira Alves ,&nbsp;Yuri Kelvin Silva Camacho Tavares ,&nbsp;Jéssica Mileny de Andrade Souza Magalhães ,&nbsp;Gesivalda Lopes Araújo ,&nbsp;Guilherme Urias Menezes Novaes ,&nbsp;Fernanda Oliveira Bomfim Rocha ,&nbsp;Ana Paula de Oliveira ,&nbsp;Jackson Roberto Guedes da Silva Almeida","doi":"10.1016/j.phytol.2024.05.013","DOIUrl":"https://doi.org/10.1016/j.phytol.2024.05.013","url":null,"abstract":"<div><p>The Northeast region of Brazil boasts a rich tradition of utilizing natural resources, particularly medicinal plants, for therapeutic purposes, especially wound healing. However, many of these plants lack comprehensive investigation into their phytochemical, pharmacological, and toxicological properties. This article presents a literature review focused on the phytochemical and pharmacological studies of medicinal plant extracts from Northeastern Brazil, renowned for their healing properties. Employing the PRISMA methodology, a thorough search of electronic databases such as PUBMED, ScienceDirect, SCOPUS, and Web of Science was conducted, yielding 16 pertinent articles. These studies revealed promising outcomes regarding the curative activity of plants from eleven different families in preclinical trials. Notably, these plants are abundant sources of biologically active compounds including flavonoids, tannins, chalcones, alkaloids, saponins, triterpenes, and steroids, crucial for wound healing. Animal models, most often the \"excision wound\" model, demonstrated that 88% of the evaluated plants expedited the healing process. Furthermore, these extracts were assessed for their antibacterial, anti-inflammatory, toxic, and antioxidant properties alongside their healing effect. Despite showcasing significant healing potential, the precise mechanisms underlying their action remain elusive, underscoring the necessity for further preclinical trials to comprehensively evaluate the healing activity of plant extracts from the northeast.</p></div>","PeriodicalId":20408,"journal":{"name":"Phytochemistry Letters","volume":"62 ","pages":"Pages 6-13"},"PeriodicalIF":1.7,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141323611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three new dammarane-type triterpenoid saponins and their cytotoxicity from steamed Panax notoginseng","authors":"Yi-Fei Yao ,&nbsp;Wei Ni ,&nbsp;Yong-Sheng Zhou ,&nbsp;Huan Yan ,&nbsp;Hai-Yang Liu","doi":"10.1016/j.phytol.2024.06.001","DOIUrl":"https://doi.org/10.1016/j.phytol.2024.06.001","url":null,"abstract":"<div><p>Three new dammarane-type triterpenoid saponins, namely 6′-crotonyl-(20 <em>S</em>)-ginsenoside Rg3 (<strong>1</strong>), 6′-crotonyl-(20 <em>R</em>)-ginsenoside Rg3 (<strong>2</strong>), and notoginsenolide A (<strong>3</strong>), were isolated from the steamed <em>Panax notoginseng</em>. Among them, <strong>3</strong> is the first tetranordamarane triterpenoid glucoside with an <em>α</em>, <em>β</em>-unsaturated <em>γ</em>-lactone group. The three isolates were evaluated for their cytotoxicities against five human cancer cell lines (HL-60, A-549, SMMC-7721, MDA-MB-231, and SW480). The results showed that compound <strong>1</strong> had moderate cytotoxicity against HL-60 cell line with an IC₅₀ value of 23.39 μM.</p></div>","PeriodicalId":20408,"journal":{"name":"Phytochemistry Letters","volume":"62 ","pages":"Pages 1-5"},"PeriodicalIF":1.7,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141289994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Announcements of the Phytochemical Society of Europe","authors":"","doi":"10.1016/S1874-3900(24)00090-9","DOIUrl":"https://doi.org/10.1016/S1874-3900(24)00090-9","url":null,"abstract":"","PeriodicalId":20408,"journal":{"name":"Phytochemistry Letters","volume":"61 ","pages":"Pages I-III"},"PeriodicalIF":1.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1874390024000909/pdfft?md5=f66b2490c7079faa672a38c86f3bbd88&pid=1-s2.0-S1874390024000909-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141323714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two new steroids with cytotoxicities from fungus Acrocalymma cycadis","authors":"Li-Bin Lin ,&nbsp;Deng-Gao Zhu ,&nbsp;Ting Yang ,&nbsp;Rui Han ,&nbsp;Jia-Yao Hu ,&nbsp;Wei Shi ,&nbsp;Ze-Yi Li ,&nbsp;Xiao-Ling Wang ,&nbsp;Jian Xiao","doi":"10.1016/j.phytol.2024.03.014","DOIUrl":"10.1016/j.phytol.2024.03.014","url":null,"abstract":"<div><p>Thirteen steroids (<strong>1</strong>–<strong>13</strong>), including two undescribed steroids, acrocalysterol C (<strong>1</strong>) and acrocalysterol D (<strong>2</strong>), were isolated from cultures of the fungus <em>Acrocalymma cycadis</em> using the OSMAC approach. Compounds <strong>1</strong> and <strong>2</strong> represent highly oxygenated steroids that contain an epoxy fragment. Through NMR and HRESIMS analyses, quantum chemical calculations, and electronic circular dichroism (ECD) experiments, their structures and absolute configurations were characterized. Then, the <em>in vitro</em> cytotoxicity of each compound was evaluated. Compounds <strong>4</strong> and <strong>8</strong>-<strong>10</strong> exhibited remarkable cytotoxicities against HeLa cells. Obviously, compound <strong>10</strong> exhibited twofold greater activity against HeLa than positive control, with IC₅₀ values of 13.2 ± 1.23 <em>μ</em>M. Additionally, compound <strong>2</strong> presented moderate potent cytotoxicity activities against three human cancer cells, comparable to the positive control. Thus, the bioactive metabolites of the strain <em>A. cycadis</em> may serve as a novel resource for development.</p></div>","PeriodicalId":20408,"journal":{"name":"Phytochemistry Letters","volume":"61 ","pages":"Pages 298-303"},"PeriodicalIF":1.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140408214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Raman spectroscopy and chemometrics to analyze bright orange floral heads from native Mexican Tagetes erecta","authors":"Alma L. Saucedo ,&nbsp;Francisco Ascencio ,&nbsp;Miguel Ángel Serrato-Cruz","doi":"10.1016/j.phytol.2024.05.012","DOIUrl":"https://doi.org/10.1016/j.phytol.2024.05.012","url":null,"abstract":"<div><p>This study presents a Raman spectroscopy analysis combined with chemometrics methodologies, using principal component analysis (PCA) and partial least squares discriminant analysis (PLS-DA) models to demonstrate the utility of this spectroscopic technique as a monitoring tool for detecting carotenoids in flower heads of <em>Tagetes erecta</em> (marigold known as cempasuchil), a symbol of the cultural heritage of Mexico. The research focuses on orange flower heads collected from various locations in the state of Guerrero, Mexico; the acquisition of Raman spectra of ligule tissue of flower heads using a 532 nm laser, and the identification and integration of five characteristic vibrational bands of the carotenoids, followed by multivariate analysis to distinguish possible groupings and samples with distinctive characteristics. The results highlight the potential of Raman spectroscopy combined with PLS-DA to detect and monitor the presence of carotenoids in genetic improvement studies.</p></div>","PeriodicalId":20408,"journal":{"name":"Phytochemistry Letters","volume":"61 ","pages":"Pages 286-291"},"PeriodicalIF":1.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141286080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The behavioral responses of Ceratitis capitata (Diptera: Tephritidae) to predominant volatile compounds of apricot","authors":"Gülsevim Ti̇ri̇ng ,&nbsp;Arif Hasanoğlu ,&nbsp;Yoav Gazit ,&nbsp;Serdar Satar","doi":"10.1016/j.phytol.2024.05.010","DOIUrl":"https://doi.org/10.1016/j.phytol.2024.05.010","url":null,"abstract":"<div><p><em>Ceratitis capitata</em> Wiedmann (Diptera: Tephritidae) is a significant pest of apricot (<em>Prunus armeniaca</em>) fruit in the spring and summer seasons in Türkiye. New integrated pest management techniques are required to reduce dependency on insecticides used for its control that may result in adverse environmental impacts. In the current study, we analyzed the volatiles emitted by apricot fruit using gas chromatography-mass spectrometry (GC-MS). We tested the behavioral responses of <em>C. capitata</em> to some of the identified compounds in the laboratory. Our results demonstrated that in four-arm olfactometer bioassays, <em>C. capitata</em> was more attracted to cis-3-hexenyl acetate and ethyl acetate than <em>(Z)-</em>2-hexenyl butyrate and the control. In the wind tunnel, the landing rate on cis-3-hexenyl acetate was higher than those on <em>(Z)</em>-2-hexenyl butyrate and ethyl acetate. Our findings may support the development of attractants for novel control strategies against <em>C. capitata</em> in orchards.</p></div>","PeriodicalId":20408,"journal":{"name":"Phytochemistry Letters","volume":"61 ","pages":"Pages 292-297"},"PeriodicalIF":1.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141286081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new acetophenone derivative from Rhododendron irroratum subsp. pogonostylum","authors":"Yong-Fu Lu,&nbsp;Si-Xuan Liu,&nbsp;Chun-Lin Guo,&nbsp;Si-Yang Dai,&nbsp;Yi-Hui Yang,&nbsp;Chang Li,&nbsp;Yue-Hu Pei","doi":"10.1016/j.phytol.2024.05.005","DOIUrl":"https://doi.org/10.1016/j.phytol.2024.05.005","url":null,"abstract":"<div><p>One previously undescribed acetophenone derivative, named as rhodoirroratin (<strong>1</strong>), was isolated from <em>Rhododendron irroratum</em> subsp. <em>pogonostylum</em> along with four known compounds (<strong>2–5</strong>), which were isolated from the genus for the first time. Their structures were elucidated on the basis of extensive spectroscopic analysis, and the absolute configuration of compound <strong>1</strong> was assigned by the calculated NMR analysis. Compounds <strong>1</strong>–<strong>3</strong> had effects on LPS-induced NO release in RAW264.7 cells.</p></div>","PeriodicalId":20408,"journal":{"name":"Phytochemistry Letters","volume":"61 ","pages":"Pages 275-279"},"PeriodicalIF":1.7,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141163850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the pulicidal potential of the essential oil of Curcuma zedoaria","authors":"Francielle Daiane de Freitas Lopes Luna ,&nbsp;Bianca Augusto de Souza ,&nbsp;Diefrey Ribeiro Campos ,&nbsp;Nathalia Soares Camargo ,&nbsp;Cristiano Jorge Riger ,&nbsp;Yara Peluso Cid ,&nbsp;Naomi Kato Simas ,&nbsp;Alaíde de Sá Barreto ,&nbsp;Raimundo Gonçalves de Oliveira Junior ,&nbsp;Douglas Siqueira de Almeida Chaves","doi":"10.1016/j.phytol.2024.05.008","DOIUrl":"https://doi.org/10.1016/j.phytol.2024.05.008","url":null,"abstract":"<div><p><em>Curcuma zedoaria</em>, commonly known as zedoary, is a plant from the Zingiberaceae family, native to India. It is currently cultivated in Brazil and countries in South and Southwest Asia. This study evaluated the bioinsecticidal potential of the essential oil (EO) obtained from C. zedoaria (Zingiberaceae) rhizomes. The EO was obtained by hydrodistillation (3 h) and identified by GC/FID/MS. <em>In vitro</em> toxicity <em>of C. zedoaria</em> essential oil was evaluated against <em>C. felis felis</em> and <em>Saccharomyces cerevisiae</em> model, and the acetylcholinesterase mechanism was analyzed. The yield was 0.15%, and the three main chemical constituents found were 1,8-cineole (24.11%), camphor (12.13%), and curzerenone (9.68%). In the bioassays of the reproductive stages of <em>C. felis felis</em> in contact with different concentrations of the essential oil, the impregnation method on filter paper was employed. The results showed that adult fleas exhibited 100 % mortality starting from the concentration of 800 μg.cm⁻² at 24 h and 48 h, differing from the pupal stages with 94.23 % mortality at the concentration of 396 μg.cm⁻², larvae with 100% mortality at the concentration of 117.5 μg.cm⁻² at 24 h and 48 h, and eggs with 98% mortality at the concentration of 396 μg.cm⁻². Regarding the inhibitory action of <em>C. zedoaria</em> EO on the acetylcholinesterase enzyme, as verified through the modified Ellman method, a decrease of approximately 20% in the enzymatic activity was observed even at the highest concentration (0.5 mg.mL⁻¹) of <em>C. zedoaria</em> essential oil. In toxicity assays using the yeast <em>S. cerevisiae</em> as a eukaryotic model, it was observed that <em>C. zedoaria</em> EO exhibited toxicity, as the assay resulted in mitochondrial damage, thus impairing cellular development. Further studies are required, as despite showing bioinsecticidal potential against different developmental stages of the flea <em>C. felis felis,</em> the EO proved to be toxic in the assays conducted with the yeast <em>S. cerevisiae</em>.</p></div>","PeriodicalId":20408,"journal":{"name":"Phytochemistry Letters","volume":"61 ","pages":"Pages 280-285"},"PeriodicalIF":1.7,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141163847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}