Pharmacy Education最新文献_第8页

Adolescent knowledge in COVID-19 prevention based on Centres for Disease Control guideline 基于疾病预防控制中心指南的青少年COVID-19预防知识

Pharmacy Education Pub Date : 2023-10-10 DOI: 10.46542/pe.2023.234.316320

Dinda Monika Nusantara Ratri, Muhammad Farid, Hasbi As-Shiddiq, Airlangga Revy Priono, Ananda Eka Putri Widhayatina, Devita Fatikhasari, Dinda Chaerani, Ellyna Majesty Ayundari, Farhan Rizqi Windianto, Kallista Freda Meir, Lie Chaterine Marthadilawati, Ludiro Seto Prasetiyo Gomo, Moch Tri Widya Octaviandy, Muhammad Rizky Naufal Ramadhan, Peggy Ignatia Winarko, Satya Andiva Azhalia, Widad Sekar Putri Rinardi

{"title":"Adolescent knowledge in COVID-19 prevention based on Centres for Disease Control guideline","authors":"Dinda Monika Nusantara Ratri, Muhammad Farid, Hasbi As-Shiddiq, Airlangga Revy Priono, Ananda Eka Putri Widhayatina, Devita Fatikhasari, Dinda Chaerani, Ellyna Majesty Ayundari, Farhan Rizqi Windianto, Kallista Freda Meir, Lie Chaterine Marthadilawati, Ludiro Seto Prasetiyo Gomo, Moch Tri Widya Octaviandy, Muhammad Rizky Naufal Ramadhan, Peggy Ignatia Winarko, Satya Andiva Azhalia, Widad Sekar Putri Rinardi","doi":"10.46542/pe.2023.234.316320","DOIUrl":"https://doi.org/10.46542/pe.2023.234.316320","url":null,"abstract":"Background: Adolescents are vulnerable to the transmission of COVID-19. Compared to the other age groups, teenagers have a lower knowledge of health protocols. This situation can lead to the continuous increase in the number of COVID-19 cases although the application of health protocols following CDC guidelines is already in place globally. Objective: The aim of this study was to determine adolescents knowledge about COVID-19 preventive measures according to CDC guidelines. Method: This study is a cross-sectional study with the snowball sampling method. It was conducted by distributing digital questionnaires in October 2021 to adolescents aged 12-18 years. Furthermore, a descriptive analysis related to knowledge and its differences was done based on the characteristics of adolescents. Result: About 80% of adolescents had good knowledge about COVID-19 preventive measures according to CDC guidelines. However, most of the adolescents did not have sufficient knowledge about proper handwashing, proper use and care of masks, and social distancing. Conclusion: Adolescent knowledge about the application of health protocols according to CDC guidelines needs to be improved. Educational interventions are needed to educate adolescents about health protocols against COVID-19.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136352569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of pharmaceutical inventory management in an Indonesian district health office: A pioneer study during the Covid-19 pandemic 印度尼西亚地区卫生办公室药品库存管理评估:2019冠状病毒病大流行期间的先驱研究

Pharmacy Education Pub Date : 2023-10-10 DOI: 10.46542/pe.2023.234.164167

Hadi Suprapto, Yunita Nita, Andi Hermansyah

{"title":"Assessment of pharmaceutical inventory management in an Indonesian district health office: A pioneer study during the Covid-19 pandemic","authors":"Hadi Suprapto, Yunita Nita, Andi Hermansyah","doi":"10.46542/pe.2023.234.164167","DOIUrl":"https://doi.org/10.46542/pe.2023.234.164167","url":null,"abstract":"Background: Pharmaceutical inventory management (PIM) is important for efficient budgeting and cost control of medicines. This is particularly critical for local health offices in Indonesia, especially during the Covid-19 pandemic. Objective: To assess the PIM in the Gunungkidul health office in Indonesia. Method: A cross-sectional descriptive study evaluating inventory data was conducted between January and May 2022. Data obtained from 2019 to 2021 were triangulated with other data from the Ministry of Health and public health centres in Gunungkidul. Results: The availability of medicine items as compared to the national formulary was 95% (2019), 94% (2020), and 90% (2021), respectively. Purchasing budget was achieved at 96% (2019), 87% (2020), and over 120% (2021), respectively. The Inventory Turnover Ratio was between 1.23 and 1.49. The shortage of medicine occurs at a minimum rate of 15% per year. This was in contrast with overstocking at 35% for a particular medicine. Expired medicine was found at the rate of 8% (2019), 5% (2020), and 13%(2021) respectively. Conclusion: The Covid-19 pandemic has presented significant challenges in the pharmaceutical inventory management in Gunungkidul as indicated by irregularities in the planning and procurement trajectories. The inability to anticipate crises due to the pandemic has contributed to poor management of pharmaceuticals.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136352582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Activities of sondhep herbs to cause changes in IL-1β in an osteoarthritis rat model 中药对骨关节炎大鼠IL-1β变化的影响

Pharmacy Education Pub Date : 2023-10-10 DOI: 10.46542/pe.2023.234.228232

Retno Widyowati, Iffatur Rosyidah, Via Qurrota A’yun, Rice Disi Oktarina, Irawati Sholikhah, Ram Kumar Sahu

引用次数: 0

Antidiabetic drug profile of COVID-19 patients with comorbid diabetes mellitus 新冠肺炎合并糖尿病患者的降糖药物分析

Pharmacy Education Pub Date : 2023-10-10 DOI: 10.46542/pe.2023.234.168172

Didik Hasmono, Samirah Samirah, Ni Putu Ayu Deviana Gayatri, Naning Ni’mawati, Halim Prihayau Jaya, Erwin Astha Triono

{"title":"Antidiabetic drug profile of COVID-19 patients with comorbid diabetes mellitus","authors":"Didik Hasmono, Samirah Samirah, Ni Putu Ayu Deviana Gayatri, Naning Ni’mawati, Halim Prihayau Jaya, Erwin Astha Triono","doi":"10.46542/pe.2023.234.168172","DOIUrl":"https://doi.org/10.46542/pe.2023.234.168172","url":null,"abstract":"Background: Diabetes mellitus (DM) is a risk factor that can increase the severity and mortality of patients with COVID-19 infection. The use of antidiabetic drugs for diabetes mellitus patients with COVID-19 infection is very important to reduce these impacts. Objective: This study aimed to determine the antidiabetic drug profiles of COVID-19 patients with comorbid diabetes mellitus. Method: This study was an analytic cross-sectional electronic medical record data of patients diagnosed with COVID-19 and comorbid Diabetes Mellitus. It was carried out from May until December 2020. Result: A total of 106 patients were involved and different types of antidiabetic drugs were used i.e., glimepiride in 32 patients (31.13%), metformin in 18 patients (16.98%), combination of long-acting and rapid-acting insulin in 20 patients (18.87%), and combination of metformin and glimepiride in 18 patients (16.98%). Conclusion: The most commonly prescribed single antidiabetic therapy in patients with COVID-19 and comorbid diabetes mellitus was glimepiride, followed by glimepiride and metformin. The most common insulin therapy combination was long-acting and rapid-acting insulin.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":"236 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136353074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of community-based sanitation management in coastal areas from an economic and financial perspective 从经济和财政角度评估沿海地区社区卫生管理

Pharmacy Education Pub Date : 2023-10-10 DOI: 10.46542/pe.2023.234.219223

None Susilawati, R. Hamdani Harahap, Miswar Budi Mulya, Lita Sri Andayani, Reinpal Falefi

引用次数: 0

Assessment of medicines and potential pharmaceutical wastes management among households in Lamongan, Indonesia 评估印度尼西亚拉蒙根家庭的药品和潜在的药品废物管理

Pharmacy Education Pub Date : 2023-10-10 DOI: 10.46542/pe.2023.234.145148

Familian Kusuma, Misbahul Munir, Ana Yuda, Andi Hermansyah

{"title":"Assessment of medicines and potential pharmaceutical wastes management among households in Lamongan, Indonesia","authors":"Familian Kusuma, Misbahul Munir, Ana Yuda, Andi Hermansyah","doi":"10.46542/pe.2023.234.145148","DOIUrl":"https://doi.org/10.46542/pe.2023.234.145148","url":null,"abstract":"Background: Storing medicines at home has been linked with irrational use, misuse, and pharmaceutical waste leading to an increased burden on the health system. Objective: This study examined the practice of storing and handling medicines at home, calculated the potential economic loss of pharmaceutical wastes, and measured the knowledge, attitude and practice (KAP) of household medicine management. Method: A cross-sectional household survey using a pre-validated ReDiUM (Return and Disposal of Unused Medications) questionnaire was conducted in Lamongan, Indonesia. A convenience sampling of 100 families was done and the findings were subsequently analysed. Results: A low portion of families (37%) obtained medicines from authorised pharmacies. The majority (68%) mentioned that housewives managed the medicines at home. More than half (57%) stated that they still keep the leftover medicines and only one-third of the respondents (37%) stored them in the medicine basket. As a result, potential economic loss was estimated at around $2 per family. The Spearman rank correlation coefficient test showed a strong positive association between knowledge and attitude (p < 0.05) Conclusion: Management of medicines at home has been an underrated topic within contemporary pharmacy research despite its potential threat to community health.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136295404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydroxyapatite (HA) scaffold supplemented with VEGF and BMP-2 growth factors enhanced osteogenic proliferation and differentiation of MC3T3-E1 cells 羟基磷灰石(HA)支架中添加VEGF和BMP-2生长因子可促进MC3T3-E1细胞成骨增殖和分化

Pharmacy Education Pub Date : 2023-10-10 DOI: 10.46542/pe.2023.234.105109

Musa Intan Maslina, Abdullah Amira Raudhah

{"title":"Hydroxyapatite (HA) scaffold supplemented with VEGF and BMP-2 growth factors enhanced osteogenic proliferation and differentiation of MC3T3-E1 cells","authors":"Musa Intan Maslina, Abdullah Amira Raudhah","doi":"10.46542/pe.2023.234.105109","DOIUrl":"https://doi.org/10.46542/pe.2023.234.105109","url":null,"abstract":"Background: Engineered bone tissue, made up of hydroxyapatite (HA) scaffold is the current alternative in bone transplant. The scaffold needs to mimic the extracellular matrix (ECM) to support bone growth and repair. Vascular endothelial growth factor (VEGF) and bone morphogenetic protein 2 (BMP-2) are vital in producing a suitable ECM environment to promote bone regeneration. Objective: To elucidate the synergistic effect of VEGF and BMP-2 growth factors on MC3T3-E1 osteoblast cells. Method: MC3T3-E1 cells were cultured in vitro and seeded onto a HA scaffold supplied with VEGF and BMP-2 growth factors. The characterisation of its mineralisation was evaluated on Day three and Day seven using the Alizarin Red staining (ARS) technique. Result: Positive ARS staining was observed in the HA scaffold supplied with VEGF and BMP-2 growth factors in vitro, thus indicating that a high level of calcium was deposited. These results suggest that the combined use of VEGF and BMP-2 will increase cell proliferation and osteoblast differentiation in vitro. Conclusion: Therefore, the synergistic effects of VEGF and BMP-2-loaded HA scaffold confirm the process as a promising approach to enhance the osteogenic effect and support cellular functions of osteoblastic cells in bone tissue engineering applications.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136352392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Profile of eye drops labelling of pharmacies’ prescription service in Surabaya 泗水市药房处方服务滴眼液标签概况

Pharmacy Education Pub Date : 2023-10-10 DOI: 10.46542/pe.2023.234.336339

Frenido Aryanto, None Syahrul Wahyudi, None Arie Sulistyarini, None Ana Yuda, None Mufarrihah

{"title":"Profile of eye drops labelling of pharmacies’ prescription service in Surabaya","authors":"Frenido Aryanto, None Syahrul Wahyudi, None Arie Sulistyarini, None Ana Yuda, None Mufarrihah","doi":"10.46542/pe.2023.234.336339","DOIUrl":"https://doi.org/10.46542/pe.2023.234.336339","url":null,"abstract":"Background: Drug labelling in prescription services is a critical stage because it contains information about the use of medicines. Objective: This study aimed to discover the drug information listed on the label of the eye drops prescription service at pharmacies in Surabaya. Method: An observational study with a cross-sectional design was used to conduct this research. Data collection was performed with the simulated patient method. The information on the label was examined using a checklist based on the “FIP Guidelines for The Labels of Prescribed Medicines” and the Minister of Health Regulation No. 73 of 2016. Result: Of 138 pharmacies visited in this study, 105 (76%) pharmacies dispensed the drug, and 83 (79%) pharmacies placed a label on the drug. The information that appeared the most was the pharmacy name (100.0%), pharmacy address (95.2%), patient name (90.4%), individual dosage instructions (100.0%), and dispensing date (88.0%). Then, the indicators that appear the least include the product name (9.6%), dosage form (2.4%), amount of drug (4.8%), expiration date (1.2%), and storage instructions (2.4%). Conclusion: Eye drops need to be maintained for their safety and efficacy. Hence, the period after opening needs to be included in the label.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136352736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Increased levels of IL-10 in the spleen after induction of pili protein 65.5 kDa Klebsiella pneumoniae 肺炎克雷伯菌菌毛蛋白65.5 kDa诱导后脾脏IL-10水平升高

Pharmacy Education Pub Date : 2023-10-10 DOI: 10.46542/pe.2023.234.304310

Dini Agustina, None Diana Chusna Mufida, None Enny Suswati, None M. Ali Shodikin, None Bagus Hermansyah, None Ajeng Samrotu Sa'adah, None Tio Wisnu Pradana Putra, None Samudra Ayu

{"title":"Increased levels of IL-10 in the spleen after induction of pili protein 65.5 kDa Klebsiella pneumoniae","authors":"Dini Agustina, None Diana Chusna Mufida, None Enny Suswati, None M. Ali Shodikin, None Bagus Hermansyah, None Ajeng Samrotu Sa'adah, None Tio Wisnu Pradana Putra, None Samudra Ayu","doi":"10.46542/pe.2023.234.304310","DOIUrl":"https://doi.org/10.46542/pe.2023.234.304310","url":null,"abstract":"Background: One of the gram-negative bacteria often found as the cause of nosocomial infections is Klebsiella pneumoniae. This bacterium has a mortality rate of 28.3% due to ESBL strains that cause resistance to several antibiotics and the absence of a vaccine as a preventive measure. Objective: To determine the level of IL-10 in the spleen after induction of the protein pili K. pneumoniae 65.5 kDa in mice. Method: This study used mice spleen samples from 21 mice aged six to eight weeks in an experimental investigation with a randomised posttest-only control group design. There are three groups, K1 as a PBS-given control, 65.5 kDa antigen protein pills + Freund’s adjuvants are given to K2, and Freund's adjuvants are given to K3. Interleukin-10 concentrations were measured using the ELISA and analysed by a one-way ANOVA assay. Result: The research showed significant differences in each group at IL-10 levels after administration of the pili protein K. pneumoniae using one-way ANOVA (p = 0.036). The treatment group had the highest average levels of IL-10, so there was an increased association between exposure to pili protein and IL-10 levels in rats. A significant increase in IL-10 levels was found in the treatment group compared to the control and adjuvant groups. Conclusion: Induction of protein pili Klebsiella pneumoniae 65.5 kDa increases IL-10 levels in spleen mice.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136353058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Food security and parenting as risk factors of stunting in toddlers aged 24 to 59 months 粮食安全和父母养育是24至59个月幼童发育迟缓的危险因素

Pharmacy Education Pub Date : 2023-10-10 DOI: 10.46542/pe.2023.234.8286

Ninna Rohmawati, Abdul Azis Akbar, Tiara Nurfaradila

引用次数: 0