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What is alopecia areata?
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 DOI: 10.1111/pde.15900
{"title":"What is alopecia areata?","authors":"","doi":"10.1111/pde.15900","DOIUrl":"https://doi.org/10.1111/pde.15900","url":null,"abstract":"<p><p>Alopecia areata is a condition that causes hair loss. It usually shows up as round patches on the scalp. Alopecia areata is one of the most common causes of hair loss in children.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":"42 Suppl 1 ","pages":"43-44"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cosmeceuticals in the Pediatric Population Part II: Ethical Dilemmas and Patient Talking Points.
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2025-02-20 DOI: 10.1111/pde.15867
Gabrielle Keller Goff, Sarah L Stein
{"title":"Cosmeceuticals in the Pediatric Population Part II: Ethical Dilemmas and Patient Talking Points.","authors":"Gabrielle Keller Goff, Sarah L Stein","doi":"10.1111/pde.15867","DOIUrl":"10.1111/pde.15867","url":null,"abstract":"<p><p>The rise in the use of cosmeceutical products amongst the pediatric population raises several ethical dilemmas, as well as new situations and questions that dermatologists must navigate with patients. Ethical concerns discussed in this review include the marketing of cosmeceutical products directly to children, the influence of social media and trends related to skincare, the use of anti-aging ingredients by children (who have not yet manifested any aging signs), and the misuse of cosmeceutical products to lighten one's complexion in childhood. We also discuss several related patient talking points for dermatologists to employ with young patients interested in cosmeceutical products.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"228-232"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950794/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accuracy of Medicaid Physician Directories of Board-Certified Pediatric Dermatologists. 委员会认证的儿科皮肤科医生的医疗补助医师目录的准确性。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-12-02 DOI: 10.1111/pde.15833
Madeleine Tessier-Kay, Eric Beltrami, Shivani Sinha, Hao Feng
{"title":"Accuracy of Medicaid Physician Directories of Board-Certified Pediatric Dermatologists.","authors":"Madeleine Tessier-Kay, Eric Beltrami, Shivani Sinha, Hao Feng","doi":"10.1111/pde.15833","DOIUrl":"10.1111/pde.15833","url":null,"abstract":"<p><p>Patients may rely on health insurance physician directories to determine who is in-network and inaccuracies in these directories may lead to delayed access to treatment, unexpected out-of-pocket costs, and increased barriers to care. This cross-sectional study quantifies the accuracy of state-specific Medicaid directories regarding board-certified pediatric dermatologists, and compares physicians listed accurately with those listed inaccurately by type of practice and region of practice. The accuracy of all state Medicaid physician directories was 84.7%. Most states with board-certified pediatric dermatologists had directories that contained inaccuracies and directory accuracy varied significantly by practice type, but not region of practice.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"326-330"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142771210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic challenge: Juvenile bullous pemphigoid with a negative BP180 ELISA. 诊断难题：BP180 酶联免疫吸附试验呈阴性的幼年大疱性类天疱疮。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-08-21 DOI: 10.1111/pde.15741
Janet A Fairley, Kristen G Berrebi, Andrew M Poggemiller, Afshin Varzavand, Kelly N Messingham
{"title":"Diagnostic challenge: Juvenile bullous pemphigoid with a negative BP180 ELISA.","authors":"Janet A Fairley, Kristen G Berrebi, Andrew M Poggemiller, Afshin Varzavand, Kelly N Messingham","doi":"10.1111/pde.15741","DOIUrl":"10.1111/pde.15741","url":null,"abstract":"<p><p>Bullous pemphigoid (BP) is an autoimmune blistering disease primarily affecting the elderly, whereas cases of juvenile BP are rare. Both types of BP are typically mediated by autoantibodies targeting the NC16A region of BP180; however, a small subset of adult patient sera react to other regions of the protein. The incidence of a similar occurrence in juvenile BP is unknown. This case of juvenile BP with a negative BP180 ELISA highlights diagnostic pitfalls that can lead to a delay in the correct diagnosis in the pediatric population.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"342-345"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shwachman-Diamond Syndrome Presenting as Neonatal Ichthyosis. 表现为新生儿鱼鳞病的 Shwachman-Diamond 综合征。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-11-18 DOI: 10.1111/pde.15804
Fatima Jacinto-Calimag, Lynette Wei Yi Wee, Mildrid Yeo Li Wen, Christopher Ho Wen Wei, Mark Jean-Aan Koh
{"title":"Shwachman-Diamond Syndrome Presenting as Neonatal Ichthyosis.","authors":"Fatima Jacinto-Calimag, Lynette Wei Yi Wee, Mildrid Yeo Li Wen, Christopher Ho Wen Wei, Mark Jean-Aan Koh","doi":"10.1111/pde.15804","DOIUrl":"10.1111/pde.15804","url":null,"abstract":"<p><p>Shwachman-Diamond syndrome (SDS) is a rare inherited bone marrow failure syndrome characterized by the triad of exocrine pancreatic dysfunction, cytopenia, and skeletal abnormalities. We report a 5-month-old boy with SDS who presented with generalized ichthyosis in the neonatal period that evolved into more eczematous skin eruptions, accompanied by severe failure to thrive. This report highlights the importance of including SDS as a differential diagnosis in patients who present with early ichthyosis, failure-to-thrive, gastrointestinal symptoms and cytopenia.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"383-386"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142667463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Folliculocentric Atrophic Papules in a 12-Year-Old Boy. 12岁男孩滤泡中心性萎缩性丘疹一例。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2025-01-08 DOI: 10.1111/pde.15795
Vishal Gaurav, Mohammad Danish, Kaushal Kumar Verma
{"title":"Folliculocentric Atrophic Papules in a 12-Year-Old Boy.","authors":"Vishal Gaurav, Mohammad Danish, Kaushal Kumar Verma","doi":"10.1111/pde.15795","DOIUrl":"10.1111/pde.15795","url":null,"abstract":"","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"404-406"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142952827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Unusual Persistent Papular Eruption in a Boy.
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2025-02-11 DOI: 10.1111/pde.15775
Alessio Natale, Marco Adriano Chessa, Alessandra Gelmetti, Luca Rapparini, Iria Neri
{"title":"An Unusual Persistent Papular Eruption in a Boy.","authors":"Alessio Natale, Marco Adriano Chessa, Alessandra Gelmetti, Luca Rapparini, Iria Neri","doi":"10.1111/pde.15775","DOIUrl":"10.1111/pde.15775","url":null,"abstract":"","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"399-400"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systemic Therapies for Pediatric Alopecia Areata.
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 DOI: 10.1111/pde.15822
Luiza Kalil, DanTasia Welch, Candrice R Heath, Brittany G Craiglow
{"title":"Systemic Therapies for Pediatric Alopecia Areata.","authors":"Luiza Kalil, DanTasia Welch, Candrice R Heath, Brittany G Craiglow","doi":"10.1111/pde.15822","DOIUrl":"https://doi.org/10.1111/pde.15822","url":null,"abstract":"<p><p>Alopecia areata (AA) is an autoimmune hair loss disorder that commonly affects children. While mild disease may improve spontaneously or with topical therapies, patients with more extensive involvement typically require systemic treatment. This narrative review examines the literature describing systemic therapies for pediatric AA. High-quality evidence is extremely limited, with the majority of evidence coming from case reports and series. Janus kinase inhibitors are the only class of medications with systematic data supporting their use. There are an increasing number of reports suggesting that oral minoxidil may be beneficial, especially as an adjunctive treatment. Some patients with AA and comorbid atopy may benefit from treatment with dupilumab. Systemic corticosteroids may provide initial improvement, but the risk for adverse effects precludes long-term use, and efficacy is often lost once discontinued. There is very little literature to support the use of traditional immunomodulatory medicines such as methotrexate, cyclosporine, and azathioprine.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":"42 Suppl 1 ","pages":"36-42"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low Infection Rates With Long-Term Dupilumab Treatment in Patients Aged 6 Months to 5 Years: An Open-Label Extension Study. 6个月至5岁患者长期使用杜匹单抗治疗感染率低：一项开放标签延伸研究。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-11-11 DOI: 10.1111/pde.15781
Amy S Paller, Michele Ramien, Michael J Cork, Eric L Simpson, Lara Wine Lee, Lawrence F Eichenfield, Faisal A Khokhar, Anna Coleman, Guy Gherardi, Zhen Chen, Annie Zhang, Sonya L Cyr
{"title":"Low Infection Rates With Long-Term Dupilumab Treatment in Patients Aged 6 Months to 5 Years: An Open-Label Extension Study.","authors":"Amy S Paller, Michele Ramien, Michael J Cork, Eric L Simpson, Lara Wine Lee, Lawrence F Eichenfield, Faisal A Khokhar, Anna Coleman, Guy Gherardi, Zhen Chen, Annie Zhang, Sonya L Cyr","doi":"10.1111/pde.15781","DOIUrl":"10.1111/pde.15781","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate long-term infection rates in children aged 6 months to 5 years with moderate-to-severe atopic dermatitis (AD) treated with dupilumab.</p><p><strong>Methods: </strong>This was a post hoc analysis of an ongoing open-label extension (OLE) study of dupilumab. Pediatric patients aged 6 months to 5 years with moderate-to-severe AD who had previously taken part in the LIBERTY AD PRESCHOOL phase 2 and 3 clinical trials received weight-based subcutaneous dupilumab every 2 or 4 weeks. Exposure-adjusted infection rates after a median dupilumab exposure of 52 weeks are compared with data from the earlier randomized, placebo-controlled, 16-week LIBERTY AD PRESCHOOL phase 3 trial.</p><p><strong>Results: </strong>Infection rates were overall lower in the OLE study compared with the dupilumab and placebo groups in the earlier 16-week trial, including total infections (101.0 patients/100 patient-years [PY]), nonherpetic skin infections (22.7 patients/100PY), herpetic infections (7.3 patients/100PY), and nonskin infections (92.9 patients/100PY). The frequency of severe and serious infections was low (3.1 patients/100PY), compared with 17.1 placebo-treated patients/100PY and 0 dupilumab-treated patients in the earlier 16-week trial, and no infections leading to treatment discontinuation were observed. Systemic anti-infective medication use (58.9 patients/100PY) was lower in the OLE study compared with both the dupilumab and placebo groups in the 16-week trial.</p><p><strong>Conclusion: </strong>Overall, reduced infection rates are observed in infants and young children with moderate-to-severe AD treated with dupilumab long-term, supporting the known safety profile of dupilumab.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"251-258"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142625574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Food Allergy Test-Guided Dietary Advice for Children With Atopic Dermatitis: A Consensus Study. 特应性皮炎儿童的食物过敏测试指导饮食建议：共识研究。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-11-11 DOI: 10.1111/pde.15807
Ludivine Garside, Robert Boyle, Rosan Meyer, Isabel Skypala, Hilary Allen, Paula Beattie, Justine Dempsey, Matt Doyle, Helen Evans-Howells, Mary Feeney, Siân Ludman, Tom Marrs, Jane Ravenscroft, Gary Stiefel, Thisanayagam Umasunthar, Deepan Vyas, Natalie Yerlett, Jo Walsh, Sara J Brown, Matthew J Ridd
{"title":"Food Allergy Test-Guided Dietary Advice for Children With Atopic Dermatitis: A Consensus Study.","authors":"Ludivine Garside, Robert Boyle, Rosan Meyer, Isabel Skypala, Hilary Allen, Paula Beattie, Justine Dempsey, Matt Doyle, Helen Evans-Howells, Mary Feeney, Siân Ludman, Tom Marrs, Jane Ravenscroft, Gary Stiefel, Thisanayagam Umasunthar, Deepan Vyas, Natalie Yerlett, Jo Walsh, Sara J Brown, Matthew J Ridd","doi":"10.1111/pde.15807","DOIUrl":"10.1111/pde.15807","url":null,"abstract":"<p><strong>Background: </strong>The use of blood specific IgE or skin prick tests (SPT) to guide dietary exclusions for disease control in children with atopic dermatitis (AD) is controversial. We undertook a consensus exercise on how to interpret SPT results and dietary history for cow's milk, hen's egg, wheat, and soy in children < 2 years old with AD.</p><p><strong>Methods: </strong>Fourteen clinicians from general practice, pediatrics, pediatric dermatology, pediatric allergy, and pediatric dietetics from UK and Ireland took part in an online modified Delphi study. Over three rounds, participants gave their anonymous opinions and received individualized and group feedback, based on the premise that all children had SPTs. The findings were discussed in an online workshop.</p><p><strong>Results: </strong>Of 18 symptoms, 12 were identified as relevant to immediate and 7 to delayed allergy. Regarding SPTs, there was consensus over which allergens to use for wheat and soy but not cow's milk or hen's egg; for all study foods, wheal size was determined as 0-1 mm negative, ≥ 5 mm sensitized, but between 2 and 4 mm, categorization varied by food. During the final workshop, consensus was reached on dietary advice for nine combinations of SPT results and dietary history.</p><p><strong>Conclusion: </strong>We attained consensus on how SPTs and dietary history for four common food allergens should be interpreted in young children under 2 years of age with AD. These pragmatic recommendations may support clinician education, consistency of decision-making, and future research.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"259-266"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142625637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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