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Pediatric Dermatology最新文献

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Rapidly Growing Neck Mass in a Newborn. 新生儿快速增长的颈部肿块。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-02-25 DOI: 10.1111/pde.15885
Mana Nasseri, Bhupender Yadav, Christopher Rossi, Liny John, A Yasmine Kirkorian
{"title":"Rapidly Growing Neck Mass in a Newborn.","authors":"Mana Nasseri, Bhupender Yadav, Christopher Rossi, Liny John, A Yasmine Kirkorian","doi":"10.1111/pde.15885","DOIUrl":"https://doi.org/10.1111/pde.15885","url":null,"abstract":"","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143502559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric Ewing's Sarcoma and Permanent Chemotherapy-Induced Alopecia: A Case-Control Study. 小儿尤文氏肉瘤与化疗引起的永久性脱发：病例对照研究
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-02-23 DOI: 10.1111/pde.15907
Madeline Lillich, Stuart Gold, Diana McShane
{"title":"Pediatric Ewing's Sarcoma and Permanent Chemotherapy-Induced Alopecia: A Case-Control Study.","authors":"Madeline Lillich, Stuart Gold, Diana McShane","doi":"10.1111/pde.15907","DOIUrl":"https://doi.org/10.1111/pde.15907","url":null,"abstract":"<p><p>Permanent chemotherapy-induced alopecia (PCIA), defined as the persistence of hair loss for > 6 months following chemotherapy cessation, is a rare pediatric diagnosis. A retrospective chart review was conducted to characterize cases of PCIA not previously reported in pediatric Ewing's sarcoma (ES) patients after completion of therapeutic chemotherapy, comparing demographic factors, cumulative chemotherapy dosing, family history of hair loss, and treatment methodologies with a control group. Of 12 patients with an history of pediatric ES, three were diagnosed with PCIA. Our findings suggest that PCIA can occur after treatment for ES in the pediatric population and that treatments, including topical and oral minoxidil, can be beneficial but may not result in complete hair regrowth.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143483869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapidly Progressive Rash Associated With Systemic Symptoms in a 5-Year-Old Girl. 1例5岁女童伴全身症状的快速进行性皮疹
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-02-20 DOI: 10.1111/pde.15883
Joselyn Ye-Tay, Brian A Moreno, Folasade F Fayiga, Ana M Duarte
{"title":"Rapidly Progressive Rash Associated With Systemic Symptoms in a 5-Year-Old Girl.","authors":"Joselyn Ye-Tay, Brian A Moreno, Folasade F Fayiga, Ana M Duarte","doi":"10.1111/pde.15883","DOIUrl":"https://doi.org/10.1111/pde.15883","url":null,"abstract":"","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperpigmented Streaks on the Sole of a 12-Year-Old Girl. 12岁女孩脚底上的色素沉着条纹。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-02-20 DOI: 10.1111/pde.15889
Shanmathi Sethumadhavan, Raman C Varsha, Saritha Mohanan, Dhayalini Raj, Raj R Remya
{"title":"Hyperpigmented Streaks on the Sole of a 12-Year-Old Girl.","authors":"Shanmathi Sethumadhavan, Raman C Varsha, Saritha Mohanan, Dhayalini Raj, Raj R Remya","doi":"10.1111/pde.15889","DOIUrl":"https://doi.org/10.1111/pde.15889","url":null,"abstract":"","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Topical Trametinib for Agminated Spitz Nevi Harboring HRAS Mutation. 局部曲美替尼治疗伴有HRAS突变的发炎的尼维斯皮兹。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-02-19 DOI: 10.1111/pde.15903
Lauren Parsons, Alice Chen, Brooke Bertus, Colleen Beatty, Julian Stashower, Patrick Tomboc, Sebastian Brooke, Zachary Zinn
{"title":"Topical Trametinib for Agminated Spitz Nevi Harboring HRAS Mutation.","authors":"Lauren Parsons, Alice Chen, Brooke Bertus, Colleen Beatty, Julian Stashower, Patrick Tomboc, Sebastian Brooke, Zachary Zinn","doi":"10.1111/pde.15903","DOIUrl":"https://doi.org/10.1111/pde.15903","url":null,"abstract":"<p><p>The treatment of agminated Spitz nevi can be challenging due to the potential for disfigurement in cosmetically sensitive areas. We report the case of a pediatric patient with progressive agminated Spitz nevi arising from a nevus spilus  on the face with an associated pathogenic HRAS p.G13R mutation revealed on next-generation sequencing (NGS). The patient was treated with compounded topical trametinib 1% cream and demonstrated significant clinical improvement following 12 weeks of twice-daily treatment. Our case highlights the potential role of MEK inhibition as a targeted, non-surgical treatment for HRAS-mutated agminated Spitz nevi and adds to the growing understanding of their genetic etiology.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atrophic Facial Plaque in a 4-Month-Old Male: An Unusual Presentation of Hair Follicle Nevus. 4个月大男性萎缩性面部斑块：一种不寻常的毛囊痣表现。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-02-16 DOI: 10.1111/pde.15899
Christine Li, Holly Neale, Isabella Plumptre, Patrick O'Donnell, Dori Goldberg, Karen Wiss, Diana Reusch
{"title":"Atrophic Facial Plaque in a 4-Month-Old Male: An Unusual Presentation of Hair Follicle Nevus.","authors":"Christine Li, Holly Neale, Isabella Plumptre, Patrick O'Donnell, Dori Goldberg, Karen Wiss, Diana Reusch","doi":"10.1111/pde.15899","DOIUrl":"https://doi.org/10.1111/pde.15899","url":null,"abstract":"<p><p>Hair follicle nevus is a rare benign follicular hamartoma that is characterized histologically by the proliferation of vellus hair follicles with peri-follicular fibrous thickening. Clinically, hair follicle nevus is most commonly reported as an asymptomatic papule or nodule on the head and neck. Here, we describe an unusual presentation of hair follicle nevus presenting as an atrophic plaque on the cheek of a male infant.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143433606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PLACK Syndrome in Two Unrelated Indian Children Caused by Novel Pathogenic Variants in the CAST Gene. 由 CAST 基因中的新型致病变异引起的两名无血缘关系印度儿童的 PLACK 综合征。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-02-11 DOI: 10.1111/pde.15823
Sahana M Srinivas, Shashikumar Basavapura
{"title":"PLACK Syndrome in Two Unrelated Indian Children Caused by Novel Pathogenic Variants in the CAST Gene.","authors":"Sahana M Srinivas, Shashikumar Basavapura","doi":"10.1111/pde.15823","DOIUrl":"https://doi.org/10.1111/pde.15823","url":null,"abstract":"<p><p>PLACK syndrome is an autosomal recessively inherited genodermatosis characterized by peeling skin, leukonychia, acral keratoses, cheilitis, and knuckle pads caused by variants in CAST gene. This report describe two unrelated Indian children with typical features of PLACK syndrome and homozygous novel variants in the CAST gene.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the Cutaneous Manifestations and Associated Comorbidities of Childhood Obesity. 评估儿童肥胖的皮肤表现和相关合并症。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-02-10 DOI: 10.1111/pde.15887
Samantha Epstein, Sonal D Shah
{"title":"Evaluating the Cutaneous Manifestations and Associated Comorbidities of Childhood Obesity.","authors":"Samantha Epstein, Sonal D Shah","doi":"10.1111/pde.15887","DOIUrl":"https://doi.org/10.1111/pde.15887","url":null,"abstract":"<p><p>Rates of childhood obesity are rising, making it a public health concern due to its link to numerous poor health outcomes over the lifespan. In adults, obesity is associated with various inflammatory skin conditions; however, this is not well-studied in children with obesity. A retrospective cohort study was conducted using the TrinetX Research Network Database, evaluating children under 18 with and without obesity and various dermatologic conditions and comorbidities. Childhood obesity was associated with increased rates of all dermatologic conditions and associated comorbidities evaluated (p < 0.05). This study highlights associations between various dermatologic conditions and comorbidities in children with obesity, compared with those without, emphasizing the need for early intervention and management strategies to mitigate obesity related health complications in pediatric populations.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143389980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acquired Digital Fibrokeratoma in a 6-Year-Old Patient: The Youngest Reported Case. 6岁后天性手指纤维角化瘤：最年轻的病例报道。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-02-09 DOI: 10.1111/pde.15888
Paul Vance, Michael Hohnadel
{"title":"Acquired Digital Fibrokeratoma in a 6-Year-Old Patient: The Youngest Reported Case.","authors":"Paul Vance, Michael Hohnadel","doi":"10.1111/pde.15888","DOIUrl":"https://doi.org/10.1111/pde.15888","url":null,"abstract":"<p><p>Acquired digital fibrokeratoma (ADF) is a rare, benign tumor most commonly seen in adults aged 30-60, with pediatric cases being exceedingly rare. We report a case of ADF in a 6-year-old male, the youngest documented patient to date, who presented with a persistent 6-mm papule on the right first finger misdiagnosed as a verruca. Histopathological examination confirmed the diagnosis, and the lesion was successfully treated with surgical excision without recurrence. This case expands the demographic understanding of ADF and underscores the importance of including it in the differential diagnosis of atypical skin lesions in pediatric patients.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Racial Differences in Disease Characteristics of Pediatric Hidradenitis Suppurativa. 小儿化脓性汗腺炎疾病特征的种族差异。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-02-09 DOI: 10.1111/pde.15891
Toluwalashe Onamusi, Jennifer Murphy, Sonal D Shah
{"title":"Racial Differences in Disease Characteristics of Pediatric Hidradenitis Suppurativa.","authors":"Toluwalashe Onamusi, Jennifer Murphy, Sonal D Shah","doi":"10.1111/pde.15891","DOIUrl":"https://doi.org/10.1111/pde.15891","url":null,"abstract":"<p><p>Understanding the potential racial differences in presentation, severity, and outcomes of pediatric hidradenitis suppurativa (HS) can help deliver equitable and individualized care, especially as this condition is increasingly being acknowledged in this population. We conducted a single-center retrospective analysis of 70 pediatric patients diagnosed with HS who were seen at our institution. There was no statistically significant difference in biologic treatments between non-Hispanic Black (NHB) patients when compared to non-Hispanic White (NHW) patients, although NHW patients overall received biologic therapy more frequently (17.4%) than NHB patients (12.8%). The observed racial differences in pediatric HS highlight the need for further investigation of possible underlying factors contributing to disease heterogeneity and treatment response to optimize the care provided and patient outcomes.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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