Pediatric Dermatology最新文献

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¿Qué son los nevos simples? 什么是单纯痣?
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 DOI: 10.1111/pde.15763
{"title":"¿Qué son los nevos simples?","authors":"","doi":"10.1111/pde.15763","DOIUrl":"https://doi.org/10.1111/pde.15763","url":null,"abstract":"<p><p>Los nevos simples, también conocidos como \"parches de salmón\" o \"marcas de la cigüeña\", son marcas de nacimiento especial en algunos recién nacidos. Son muy comunes y no causan dolor.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142351625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eye and lid involvement as an uncommon feature of pemphigus foliaceus in a pediatric patient. 一名儿童患者的眼部和眼睑受累,这是一种不常见的丘疹性红斑狼疮。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 Epub Date: 2024-03-08 DOI: 10.1111/pde.15594
Valeria F Garza-Dávila, Adalberto Santana-Gutiérrez, Natalia Zapata-Salazar, Osvaldo Vázquez-Martínez, Jorge Ocampo-Candiani, Marissa L Fernández-de Luna, Karim Mohamed-Noriega, Erika Alba-Rojas
{"title":"Eye and lid involvement as an uncommon feature of pemphigus foliaceus in a pediatric patient.","authors":"Valeria F Garza-Dávila, Adalberto Santana-Gutiérrez, Natalia Zapata-Salazar, Osvaldo Vázquez-Martínez, Jorge Ocampo-Candiani, Marissa L Fernández-de Luna, Karim Mohamed-Noriega, Erika Alba-Rojas","doi":"10.1111/pde.15594","DOIUrl":"10.1111/pde.15594","url":null,"abstract":"<p><p>Pemphigus foliaceus (PF) is an autoimmune blistering disorder which affects the superficial layers of the epidermis with rare mucosal involvement. We present the case of a 12-year-old girl with PF involving the eyes and eyelids. A literature review of pediatric nonendemic PF revealed another two cases with ocular manifestations. Eyelid involvement is an uncommon feature of PF that should be properly identified and treated.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140065629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The elusive BAP1 mutation in pediatric melanocytic tumors. 小儿黑色素细胞肿瘤中难以捉摸的 BAP1 基因突变。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 Epub Date: 2024-07-30 DOI: 10.1111/pde.15705
Danna Moustafa, Mia A Mologousis, Lyn M Duncan, Elena B Hawryluk
{"title":"The elusive BAP1 mutation in pediatric melanocytic tumors.","authors":"Danna Moustafa, Mia A Mologousis, Lyn M Duncan, Elena B Hawryluk","doi":"10.1111/pde.15705","DOIUrl":"10.1111/pde.15705","url":null,"abstract":"<p><p>Cutaneous BAP1-inactivated melanocytomas (BIM) are melanocytic proliferations defined histopathologically by an epithelioid, predominantly dermal melanocytic proliferation with loss of BAP1, and have been largely characterized in adult patients but less well-described in pediatric cohorts. BIM share overlapping histological features with those seen in Spitz nevi; however, unlike Spitz nevi, the majority of BIM carry both BAP1 and BRAF<sup>V600E</sup> mutations. This study investigated the potential overlap of BIMs with pediatric Spitz nevi by performing immunohistochemical staining of BAP1 and BRAF<sup>V600E</sup> on pediatric melanocytic tumors with banal Spitz and dermal features. None of the stained tumors in our study exhibited the concurrent BAP1 loss and BRAF<sup>V600E</sup> positivity that are characteristic of adult BIM, suggesting that this is a low-frequency mutation among banal tumors in the pediatric population.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Periungual pyogenic granulomas after ravulizumab therapy in a child with acute myelomonocytic leukemia treated with hematopoietic stem cell transplant. 一名接受造血干细胞移植治疗的急性髓单核细胞白血病患儿在接受雷珠单抗治疗后出现毛周化脓性肉芽肿。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 Epub Date: 2024-06-10 DOI: 10.1111/pde.15675
Helena Iznardo, Ivan López-Torija, Laura Mateu-Arrom, Pablo Escribano-Sanz, Lluís Puig, Esther Roé
{"title":"Periungual pyogenic granulomas after ravulizumab therapy in a child with acute myelomonocytic leukemia treated with hematopoietic stem cell transplant.","authors":"Helena Iznardo, Ivan López-Torija, Laura Mateu-Arrom, Pablo Escribano-Sanz, Lluís Puig, Esther Roé","doi":"10.1111/pde.15675","DOIUrl":"10.1111/pde.15675","url":null,"abstract":"<p><p>Development of periungual pyogenic granulomas (pPGs) has been associated with several systemic treatments, including retinoids, taxanes, epidermal growth factor receptor inhibitors, and vascular endothelial growth factor inhibitors. We present the case of an 8-year-old girl with a personal history of acute myelomonocytic leukemia treated with a haploidentical hematopoietic stem cell transplant who developed pPGs 2 months after starting ravulizumab. Ravulizumab is a monoclonal antibody directed against C5 protein. No previous reports of pPGs development have been described with ravulizumab.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141301297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
'I need to understand… so we can decide together': Difficult conversations about alopecia areata. 我需要了解......这样我们才能一起做出决定":关于斑秃的艰难对话。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 Epub Date: 2024-06-28 DOI: 10.1111/pde.15684
Kristin A Tissera, Kristina Gorbatenko-Roth, Neil S Prose, Kirsten Johnson
{"title":"'I need to understand… so we can decide together': Difficult conversations about alopecia areata.","authors":"Kristin A Tissera, Kristina Gorbatenko-Roth, Neil S Prose, Kirsten Johnson","doi":"10.1111/pde.15684","DOIUrl":"10.1111/pde.15684","url":null,"abstract":"<p><p>The management of alopecia areata (AA) in pediatric patients poses unique challenges, particularly regarding treatment discussions and decision making involving both patients and their families. This commentary presents findings from unpublished research on treatment-discontinuation discussions between AA patients and their treating providers, shedding light on the hopes, expectations, and disappointments of individuals with severe AA. The study explored patient and guardian satisfaction with these discussions, emphasizing the importance of addressing psychosocial concerns, facilitating contact with support groups, and demonstrating empathy. The role of dermatologists in conversations about treatment, prognosis, and quality of life is examined, emphasizing the need for honesty, empathy, and realistic expectations. The authors propose a patient-centered approach to initiating and guiding discussions, focusing on understanding the impact of AA on patients and their families and collaboratively deciding on treatment options. The mantra: 'I need to understand how this is affecting all of you, so we can decide together what to do next' is central to this proposed approach. Special considerations for different scenarios are discussed, highlighting the importance of individualized care and effective communication. Overall, the commentary emphasizes the significance of actively listening, acknowledging emotions, and prioritizing patient and family goals to optimize care for pediatric AA patients.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141470047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two siblings with uncombable hair syndrome: A new pathogenic variant. 两兄妹患有不稳定毛发综合征:一种新的致病变体
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 Epub Date: 2024-03-08 DOI: 10.1111/pde.15590
Carlos Calvo-Asín, Sara I Palencia-Pérez, Juan F Quesada-Espinosa, Jose Puig-Buendia, Raquel Cavestany-Rodríguez, Virginia Velasco-Tamariz
{"title":"Two siblings with uncombable hair syndrome: A new pathogenic variant.","authors":"Carlos Calvo-Asín, Sara I Palencia-Pérez, Juan F Quesada-Espinosa, Jose Puig-Buendia, Raquel Cavestany-Rodríguez, Virginia Velasco-Tamariz","doi":"10.1111/pde.15590","DOIUrl":"10.1111/pde.15590","url":null,"abstract":"<p><p>Two siblings presented with straw-colored, frizzy, and wiry hair. They had no associated abnormalities and no family history of abnormal hair. Trichoscopy showed the longitudinal groove in the hair shafts, characteristic of uncombable hair syndrome. Molecular genetic analysis revealed a new pathogenic variant (c.1374dup; p. Val459ArgfsTer15) in PADI3, not previously described.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140060151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Scrofuloderma of the chest with mediastinal TB. 胸部瘰疬性皮肤病伴纵隔结核。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 Epub Date: 2024-03-22 DOI: 10.1111/pde.15607
Vanessa Bustamante Estrada, Ana Claudia Lada Lemos, Pedro Machado Luz, Iara Regina Siqueira Lucena, Valentina Coutinho Baldoto Gava Chakr, Anneliese Hoffmann
{"title":"Scrofuloderma of the chest with mediastinal TB.","authors":"Vanessa Bustamante Estrada, Ana Claudia Lada Lemos, Pedro Machado Luz, Iara Regina Siqueira Lucena, Valentina Coutinho Baldoto Gava Chakr, Anneliese Hoffmann","doi":"10.1111/pde.15607","DOIUrl":"10.1111/pde.15607","url":null,"abstract":"<p><p>Cutaneous tuberculosis is a rare manifestation of extrapulmonary tuberculosis caused by Mycobacterium tuberculosis in most cases and rarely by Mycobacterium bovis. Diagnosis may be challenging due to a wide range of clinical findings and similarities to other chronic dermatoses, leading to delayed treatment. We present a case of scrofuloderma in a 4-year-old girl that arose from a contiguous spread from the anterior mediastinum with associated pulmonary involvement.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140185132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chlorhexidine gluconate for antisepsis in preterm neonates: A review of safety and efficacy. 葡萄糖酸氯己定用于早产新生儿的防腐:安全性和有效性综述。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 Epub Date: 2024-07-25 DOI: 10.1111/pde.15709
Jamie B Harris, Reesa L Monir, Jennifer J Schoch
{"title":"Chlorhexidine gluconate for antisepsis in preterm neonates: A review of safety and efficacy.","authors":"Jamie B Harris, Reesa L Monir, Jennifer J Schoch","doi":"10.1111/pde.15709","DOIUrl":"10.1111/pde.15709","url":null,"abstract":"<p><p>Sepsis is a leading cause of death in preterm neonates. The increased susceptibility to sepsis is due to prolonged hospitalization, the need for invasive procedures, and immaturity of innate and adaptive immunity. Chlorhexidine gluconate is a popular topical disinfectant that was not recommended for use in preterm neonates until 2012. Thus, there are few studies assessing the role of chlorhexidine gluconate in antisepsis for preterm neonates. A better understanding of the safety and efficacy of chlorhexidine gluconate as an antiseptic agent for preterm neonates is the first step in establishing best practice guidelines for this population.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11427162/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141760286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute hemorrhagic edema of infancy: 20-year experience from an Italian tertiary referral center. 婴儿急性出血性水肿:意大利一家三级转诊中心的 20 年经验。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 Epub Date: 2024-07-18 DOI: 10.1111/pde.15707
Adele Fiordelisi, Sara Soldovieri, Ilaria Pagnini, Edoardo Marrani, Gabriele Simonini, Giuseppe Indolfi, Sandra Trapani
{"title":"Acute hemorrhagic edema of infancy: 20-year experience from an Italian tertiary referral center.","authors":"Adele Fiordelisi, Sara Soldovieri, Ilaria Pagnini, Edoardo Marrani, Gabriele Simonini, Giuseppe Indolfi, Sandra Trapani","doi":"10.1111/pde.15707","DOIUrl":"10.1111/pde.15707","url":null,"abstract":"<p><strong>Purpose: </strong>Data on acute hemorrhagic edema of infancy (AHEI) are derived from small case series or case reports. We report a 20-year experience at a national referral center.</p><p><strong>Methods: </strong>We performed a single-center retrospective study including patients who were diagnosed with AHEI from January 1, 2004, to June 30, 2023.</p><p><strong>Results: </strong>We identified 21 patients (57.1% females) with a median age of 18 months (range 7-33 months). Thirteen (61.9%) patients were admitted to the pediatric ward, the remaining eight (38.1%) presented to the emergency department and were discharged for outpatient management. The median length of hospitalization was 5 days (range 3-9 days). Twenty patients (95.2%) had prodromal symptoms. The most common cutaneous findings were targetoid purpuric plaques. The lesions were most localized on the face (13, 61.9%) and on the upper limbs (18 patients, 85.7%). Sixteen (76%) patients presented with nonpitting and tender edema, localized on the feet (9/16, 56%) and hands (6/16, 37.5%). Systemic involvement was rare, and no patients experienced complications or sequelae. Twelve (57.1%) patients underwent infectious disease investigations, with positive results in only four (33.3%). None of the patients diagnosed after the SARS-CoV-2 outbreak (March 2020) had positive nasopharyngeal swabs for the virus. For the 13 patients who were admitted to the pediatric ward, the median length of hospitalization was five days (3-9 days).</p><p><strong>Conclusions: </strong>The 21-patient single-center cohort of children affected by AHEI confirmed a generally benign course of AHEI, despite a 62% rate of hospitalization.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141634162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Topical everolimus therapy for epidermal nevi associated with woolly hair nevus in a patient with a mosaic HRAS mutation. 外用依维莫司治疗一名HRAS基因突变患者的表皮痣和毛发痣。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 Epub Date: 2024-04-01 DOI: 10.1111/pde.15605
Akaljot Singh, Emily S Gorell, Anne W Lucky
{"title":"Topical everolimus therapy for epidermal nevi associated with woolly hair nevus in a patient with a mosaic HRAS mutation.","authors":"Akaljot Singh, Emily S Gorell, Anne W Lucky","doi":"10.1111/pde.15605","DOIUrl":"10.1111/pde.15605","url":null,"abstract":"<p><p>A patient with woolly hair nevus syndrome, presented with epidermal facial nevi by the age of 12 years. Despite transient improvement with topical 1% sirolimus cream, the facial nevus grew larger. The patient was then treated with topical 1% everolimus cream resulting in a reduction in the size of the nevus. This case highlights a novel use of topical 1% everolimus cream, which previously has not been used to treat epidermal nevi.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140336487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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