Pediatric Dermatology最新文献_第9页

Decreased Sleep Duration and Increased Use of Medication to Aid Sleep Among Parents of Children With Atopic Dermatitis: A Cross-Sectional Study of the National Health Interview Survey, 2013-2018. 特应性皮炎患儿家长睡眠时间减少和使用助眠药物增加：2013-2018年全国健康访谈调查横断面研究》。

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-12-12 DOI: 10.1111/pde.15839

Christopher G Youn, Joo Yeon Kim, Jennifer K Chen, Dawn H Siegel

引用次数: 0

Oral propranolol and its impact on vital signs in hospitalized pediatric patients for the Management of Infantile Hemangiomas.

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2025-02-18 DOI: 10.1111/pde.15740

Katelyn Rypka, Gretchen Bellefeuille, Zachary Wendland, Briana Paiewonsky, Rebecca Freese, Sheilagh Maguiness, Cynthia Nicholson

{"title":"Oral propranolol and its impact on vital signs in hospitalized pediatric patients for the Management of Infantile Hemangiomas.","authors":"Katelyn Rypka, Gretchen Bellefeuille, Zachary Wendland, Briana Paiewonsky, Rebecca Freese, Sheilagh Maguiness, Cynthia Nicholson","doi":"10.1111/pde.15740","DOIUrl":"10.1111/pde.15740","url":null,"abstract":"Background: Infantile hemangiomas (IH) affect 2%-10% of the pediatric population. The current standard treatment for complicated IH is oral propranolol. Propranolol initiation protocols vary depending on institution and may occur in an inpatient setting for patients <5-week-corrected-age, with a history of premature birth, and or with low weight to allow for heart rate (HR), blood pressure (BP), and glucose monitoring.Objective: Our study aimed to determine the clinical outcomes of monitoring inpatient propranolol initiation and to evaluate if complications occurred during admission.Methods: Retrospective chart review of patients seen at the University of Minnesota Department of Dermatology between January 01, 2012 and July 31, 2022 was completed. Inclusion criteria include less than 1 year of age at time of admission, a diagnosis of IH and or PHACE syndrome, and admission for propranolol initiation and monitoring.Results: Admissions for 78 pediatric patients were reviewed. After initiation of propranolol, significant decreases in BP (systolic p = .005; diastolic p = .002) and HR (p = .004) were noted; however, average BPs and HRs remained above the lower limit of normal. No patients experienced symptomatic hypoglycemia. No statistically significant or clinically meaningful differences in vital sign alterations were observed between patients <5 versus >5 kg; preterm vs term gestation; or <5-week-corrected-age versus >5-week-corrected-age.Discussion: Our findings complement current literature confirming that propranolol initiation is safe in pediatric patients. Propranolol initiation likely requires less laboratory and vital sign monitoring than currently performed for these patient populations.","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"245-250"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950798/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pemphigus Vulgaris With Esophageal Involvement in an Atopic Child Successfully Treated With Dupilumab. 杜匹单抗成功治疗特应性儿童的寻常型天疱疮伴食管累及。

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-12-11 DOI: 10.1111/pde.15779

Sonora Yun, Blair A Jenkins, Margaret E Scollan, Amy R Defelice, Kristin M Leiferman, Joshua D Milner, Christine T Lauren

引用次数: 0

Transfusion-Associated Graft-Versus-Host Disease in Pediatric Patients: Clinical Features and Outcomes. 小儿输血相关性移植物抗宿主疾病：临床特征与疗效

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-11-24 DOI: 10.1111/pde.15812

Isabel Araiza-Atanacio, Marimar Sáez-de-Ocariz, Luz Orozco-Covarrubias

{"title":"Transfusion-Associated Graft-Versus-Host Disease in Pediatric Patients: Clinical Features and Outcomes.","authors":"Isabel Araiza-Atanacio, Marimar Sáez-de-Ocariz, Luz Orozco-Covarrubias","doi":"10.1111/pde.15812","DOIUrl":"10.1111/pde.15812","url":null,"abstract":"Background: Transfusion-associated graft-versus-host disease (TA-GVHD) is a rare, usually fatal complication of blood transfusion.Objective: To describe the characteristics of TA-GVHD in children.Methods: The clinical records of pediatric patients diagnosed with TA-GVHD between January 2007 and December 2021 were reviewed.Results: We analyzed 94 clinical records of pediatric patients (0-18 years) with a diagnosis of GVHD, of whom 6 (6.38%) were associated with TA-GVHD; both genders being equally affected. The median age at diagnosis of the underlying disorder was 9 years, 1 month (range 2 months-15 years, 3 months); the median age at diagnosis of TA-GVHD was 9 years, 5.5 months (range 1 year, 7 months-15 years, 7 months). There were 27 grafts; 8 were irradiated and 12 were filtered. All patients presented with Stage 3 cutaneous TA-GVHD and histopathological Grade 2. All cases corresponded to classic acute TA-GVHD with global clinical Grade I-II. Mortality rate was 67%. The median follow-up of our patients was 2 years and 2 months (range 4 months-3 years, 4 months).Conclusions: TA-GVHD, although less frequently encountered than in previous years, is still a concern. Early suspicion of TA-GVHD is mandatory due to its high mortality rates and rapid progression. Prevention by using irradiated blood products is the sole effective measure against this condition. Failing to identify and preempt TA-GVHD not only jeopardizes patient survival but also underscores the critical importance of vigilant monitoring and proactive intervention in at-risk patients.","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"267-272"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Moisturizer Use in Children With Atopic Dermatitis: Real-Life Practice, Beliefs, and Challenges Among a Cohort of Jordanian Patients. 儿童特应性皮炎患者使用保湿霜的情况：约旦患者群体中的实际做法、信念和挑战。

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-11-25 DOI: 10.1111/pde.15821

Jihan Muhaidat, Alsharif Mohammad Fawwaz, Firas Al-Qarqaz, Diala Alshiyab, Ashaar-Akhras, Mohammad Mustafa Ababneh, Alina Ghazou, Shaden Tashtoush, Touga Abdelnabi

{"title":"Moisturizer Use in Children With Atopic Dermatitis: Real-Life Practice, Beliefs, and Challenges Among a Cohort of Jordanian Patients.","authors":"Jihan Muhaidat, Alsharif Mohammad Fawwaz, Firas Al-Qarqaz, Diala Alshiyab, Ashaar-Akhras, Mohammad Mustafa Ababneh, Alina Ghazou, Shaden Tashtoush, Touga Abdelnabi","doi":"10.1111/pde.15821","DOIUrl":"10.1111/pde.15821","url":null,"abstract":"Background: Moisturizers are a crucial baseline therapy for atopic dermatitis (AD).Objective: To evaluate the real-life experience of using moisturizers in AD patients and to assess parents' opinions and challenges regarding moisturizer use.Methods: This cross-sectional study used a questionnaire completed by the parents of pediatric AD patients. The assessment questionnaire evaluated demographic factors as well as practices, opinions, and challenges regarding the use of moisturizers in AD treatment. Applying moisturizers twice daily, considered sufficient use, was evaluated across demographic levels using bivariate analysis.Results: A total of 425 patients with AD participated in the study. The median age was 4 years, 51% of patients were female, 61% had moderate to severe AD, 34% had a family history of AD, and 41% of cases reported sufficient moisturizer use. Factors associated with increased frequency of application of moisturizers included younger age at diagnosis, higher parents' educational level, and increased family income. The twice-daily application versus less frequent application was associated with fewer monthly flare-ups (33% vs. 17%, p < 0.001). Overall, 54% of patient guardians believed that moisturizers were necessary for treating AD, 69% considered fragrance-free formulas to be better, and 86% thought there to be a need for counseling from their physician on using moisturizers in AD treatment. Factors undermining the application of moisturizers included the time needed for application, cost, and lack of patient cooperation.Conclusion: In real-world practice, parents tend to underutilize moisturizers. To address this issue, treating physicians must provide additional education, and health insurance companies should consider covering moisturizers to ensure their accessibility.","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"289-295"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142716839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Infant With Congenital Scalp, Nail, and Limb Anomalies.

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2025-02-11 DOI: 10.1111/pde.15815

Sabrina Yang, Joseph M Lam

引用次数: 0

Cutaneous Manifestations of NAXD or NAXE Deficiency: A Literature Review for the Dermatologist.

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2025-01-31 DOI: 10.1111/pde.15868

Boraan Abdulkarim, Setu Mittal, Hassan Vahidnezhad, Dawn Marie Davis, Michael J Camilleri, Nessa Aghazadeh Mohandesi

{"title":"Cutaneous Manifestations of NAXD or NAXE Deficiency: A Literature Review for the Dermatologist.","authors":"Boraan Abdulkarim, Setu Mittal, Hassan Vahidnezhad, Dawn Marie Davis, Michael J Camilleri, Nessa Aghazadeh Mohandesi","doi":"10.1111/pde.15868","DOIUrl":"10.1111/pde.15868","url":null,"abstract":"Nicotinamide adenine dinucleotide phosphate hydrate dehydratase (NAXD) and nicotinamide adenine dinucleotide phosphate hydrate epimerase (NAXE) deficiencies are rare autosomal recessive metabolic disorders characterized by severe neurological manifestations during infancy. In affected individuals, febrile illnesses can trigger progressive encephalopathy often accompanied by distinctive skin eruptions, resulting in high mortality rates. This study reviews the literature on NAXD/NAXE deficiencies, focusing on dermatological manifestations and their correlation with genotypic variations and treatment responses. A comprehensive literature search identified 45 patients with 31 pathogenic/likely pathogenic mutations, and a median age of onset at 1.16 years. Patients with NAXE deficiency exhibited a broader range of age of symptom onset compared to those affected with NAXD deficiency. Fever or infections were identified as the most common triggers for decompensation episodes. Skin manifestations were observed in 31% of patients with whole cell NAXD and NAXE deficiencies. The characteristic skin eruption comprises well-demarcated erythematous and erosive plaques progressing to blistering and necrosis, predominantly affecting flexural surfaces. The mortality rate was 78%, with survivors experiencing varying degrees of neurological sequelae. Niacin/nicotinamide supplementation resulted in improvements in skin lesions and survival rates. The review underscores the critical role of dermatologists in early diagnosis and intervention of NAXE and NAXD deficiencies. Recognizing characteristic skin manifestations is essential, particularly in patients with acute neurological decline following infections or vaccinations. Early intervention with specific supplements shows promise; however, further research is needed to establish standardized treatment protocols and enhance patient outcomes.","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"233-239"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phototherapy-Induced Yellow Urticaria in a Neonate.

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-02-26 DOI: 10.1111/pde.15911

Maryem Aboudourib, Ouiam Karim, Abdessamad El Alaoui, Fadl Mrabih Rabih Maoulainine, Said Amal, Ouafa Hocar

引用次数: 0

Ichthyosis Prematurity Syndrome: A Systematic Review of the Literature.

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-02-25 DOI: 10.1111/pde.15909

Grace X Li, Kathryn Chen, Deshan F Sebaratnam, James P Pham

{"title":"Ichthyosis Prematurity Syndrome: A Systematic Review of the Literature.","authors":"Grace X Li, Kathryn Chen, Deshan F Sebaratnam, James P Pham","doi":"10.1111/pde.15909","DOIUrl":"https://doi.org/10.1111/pde.15909","url":null,"abstract":"Background/objectives: Ichthyosis prematurity syndrome (IPS) is a rare autosomal recessive congenital disorder characterized by premature birth, neonatal respiratory distress, eosinophilia, and a thick, clay-like vernix at birth. This review aims to summarize the available reported cases of IPS, including genetic etiology, clinical features, management, and prognosis.Methods: A search was conducted using MEDLINE, Embase, Scopus, Web of Science, and CINAHL, from inception to September 3, 2024 using the search terms \"IPS\" or \"ichthyosis congenita type IV\". This systematic review was registered on the PROSPERO database (CRD42024533988). Any publication reporting a case of IPS was suitable for inclusion. Quality appraisal was performed according to CARE guidelines. Descriptive statistical analysis was performed using R v4.3.1 (R Foundation, Vienna, Austria).Results: We identified 26 studies reporting 59 cases of IPS (PROSPERO database: CRD42024533988). While IPS was previously thought to predominantly affect Norwegian and Swedish patients, we identified cases from a broad range of ethnicities. The median duration of the cutaneous scale was 10 weeks, though patients usually have persisting atopy. Long-term prognosis is generally good, although six (10.2%) fulminant cases were identified with an estimated 6-month survival rate of 87.6% (95% confidence interval: 78.8-97.4). Mortality in these cases was attributed to respiratory and/or cardiac sequelae or sepsis. Limitations include heterogeneity in the reporting of cases and low quality of data in several aspects of data collection.Conclusions: The cutaneous manifestations of IPS resolve over a period of weeks, and patients generally have a favorable long-term prognosis. However, rare cases of death and other complications have been reported.","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143502556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Basiliximab for IL-2-Associated Inflammatory Disorder With Atopic Dermatitis.

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-02-25 DOI: 10.1111/pde.15913

Sarah L Becker, Liza Kenny, Alison Small

引用次数: 0