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A Case of Congenital Alopecia Areata Successfully Diagnosed by Integrating Clinical, Trichoscopic, and Scalp Biopsy Findings.
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-04-04 DOI: 10.1111/pde.15939
Erina Taniguchi, Hisayoshi Imanishi, Shigeki Inui, Manabu Ohyama, Daisuke Tsuruta
{"title":"A Case of Congenital Alopecia Areata Successfully Diagnosed by Integrating Clinical, Trichoscopic, and Scalp Biopsy Findings.","authors":"Erina Taniguchi, Hisayoshi Imanishi, Shigeki Inui, Manabu Ohyama, Daisuke Tsuruta","doi":"10.1111/pde.15939","DOIUrl":"https://doi.org/10.1111/pde.15939","url":null,"abstract":"<p><p>Congenital alopecia areata is a rare and diagnostically challenging disease. Histopathological findings are helpful for diagnosis; however, patients and their guardians might be reluctant to give consent for skin biopsies due to their concern about the invasiveness of the procedure and potential scar formation at biopsy sites. Herein, we report a case of congenital alopecia areata in which a biopsy procedure was essential for the final diagnosis, even though clinical and trichoscopic findings were suggestive of the condition. Based on a literature review, no non-invasively obtainable and reliable finding exists for diagnosing congenital alopecia areata and, therefore, scalp biopsy still holds diagnostic significance.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143780821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Juvenile Intermittent Facial Flushing: A New Entity in Children.
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-04-03 DOI: 10.1111/pde.15948
Marie-Chantal Caussade, María Trinidad Hasbún Zegpi, Shudeshna Nag, Albert C Yan
{"title":"Juvenile Intermittent Facial Flushing: A New Entity in Children.","authors":"Marie-Chantal Caussade, María Trinidad Hasbún Zegpi, Shudeshna Nag, Albert C Yan","doi":"10.1111/pde.15948","DOIUrl":"https://doi.org/10.1111/pde.15948","url":null,"abstract":"<p><p>The differential diagnosis of flushing is extensive, encompassing benign and malignant entities. In this study, we herein describe three patients under 2 years of age who had similarly striking presentations of recurrent unilateral and bilateral facial flushing of unknown etiology that improved spontaneously over time. We propose the term \"juvenile intermittent facial flushing\" to designate this entity until we better understand its spectrum of underlying causes and determine whether this is a specific disorder or a broader phenotype for a heterogeneous group of disorders.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dental Developmental Anomalies in Facial Segmental Hemangiomas Not Related to PHACES.
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-04-03 DOI: 10.1111/pde.15938
Eduardo López-Vera, Javier Del Boz-González, Julia Castro-Ruiz, Francisco Ruiz-Delgado
{"title":"Dental Developmental Anomalies in Facial Segmental Hemangiomas Not Related to PHACES.","authors":"Eduardo López-Vera, Javier Del Boz-González, Julia Castro-Ruiz, Francisco Ruiz-Delgado","doi":"10.1111/pde.15938","DOIUrl":"https://doi.org/10.1111/pde.15938","url":null,"abstract":"<p><p>The dental developmental abnormalities observed in two pediatric patients with segmental infantile hemangiomas (IH) not associated with PHACES syndrome (posterior fossa malformations, hemangiomas, arterial anomalies, cardiac defects, eye abnormalities, sternal cleft, and supraumbilical raphe) are presented. Both patients, treated with oral propranolol, exhibited significant dental complications, including delayed tooth eruption, enamel hypoplasia, and complete tooth agenesis. The findings suggest a potential link between facial segmental IH and dental anomalies that may be underrecognized, particularly in non-PHACES cases. We recommend considering targeted dental screenings and radiographic imaging for patients with segmental IH in high-risk facial regions, particularly those involving the maxillary and mandibular regions, to facilitate early identification and management of potential complications.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prospective Clinical Study of Newborn Fingernails Including Onychoscopy. 新生儿指甲前瞻性临床研究，包括虹膜镜检查。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-04-03 DOI: 10.1111/pde.15936
Stephano Cedirian, Francesca Pampaloni, Luca Rapparini, Federico Quadrelli, Francesca Bruni, Iria Neri, Aurora M Alessandrini, Bianca M Piraccini, Michela Starace
{"title":"Prospective Clinical Study of Newborn Fingernails Including Onychoscopy.","authors":"Stephano Cedirian, Francesca Pampaloni, Luca Rapparini, Federico Quadrelli, Francesca Bruni, Iria Neri, Aurora M Alessandrini, Bianca M Piraccini, Michela Starace","doi":"10.1111/pde.15936","DOIUrl":"https://doi.org/10.1111/pde.15936","url":null,"abstract":"<p><p>The literature provides limited information on healthy nail features in newborns, emphasizing a need for comprehensive studies on their physiological characteristics. A prospective observational study was conducted at a single pediatric center in Bologna, Italy. Both clinical and onychoscopic evaluations were performed to assess fingernail dimensions, shapes, colors, and other features. This study highlights key physiological fingernail features in newborns, demonstrating sex variation.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multifocal PIK3CA Related Congenital Hemangioma.
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-04-03 DOI: 10.1111/pde.15943
Patricia Andres-Ibarrola, Irune Méndez Maestro, Aitor Fernádez de Larrinoa Santamaría, Cristina Barcelona Alfonso, Estibaliz Solórzano Rodríguez, Ricardo López Alcaraz, María Jose Beato Merino, Lara Rodríguez-Laguna, Victor Martinez-Glez, Juan Carlos López Gutiérrez, Marta Mendieta Eckert, Maria Rosario Gonzalez-Hermosa
{"title":"Multifocal PIK3CA Related Congenital Hemangioma.","authors":"Patricia Andres-Ibarrola, Irune Méndez Maestro, Aitor Fernádez de Larrinoa Santamaría, Cristina Barcelona Alfonso, Estibaliz Solórzano Rodríguez, Ricardo López Alcaraz, María Jose Beato Merino, Lara Rodríguez-Laguna, Victor Martinez-Glez, Juan Carlos López Gutiérrez, Marta Mendieta Eckert, Maria Rosario Gonzalez-Hermosa","doi":"10.1111/pde.15943","DOIUrl":"https://doi.org/10.1111/pde.15943","url":null,"abstract":"<p><p>The case of a newborn with multifocal congenital hemangiomas with an activating pathogenic variant of PIK3CA is presented. This report highlights the difficulty in diagnosing multifocal vascular lesions in newborns. Additionally, this case emphasizes the importance of clinical, histologic, radiographic, and genomic correlation to the best categorize rare vascular lesions and to guide treatment.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polarized Transilluminating Dermoscopy in Diagnosis of Hair Shaft Disorders. 偏振透射皮肤镜在诊断发轴疾病中的应用。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-04-03 DOI: 10.1111/pde.15922
Neha Fogla, Usha N Khemani, Avinash A Sajgane, Gampi Ete, Ratnakar R Kamath
{"title":"Polarized Transilluminating Dermoscopy in Diagnosis of Hair Shaft Disorders.","authors":"Neha Fogla, Usha N Khemani, Avinash A Sajgane, Gampi Ete, Ratnakar R Kamath","doi":"10.1111/pde.15922","DOIUrl":"https://doi.org/10.1111/pde.15922","url":null,"abstract":"<p><strong>Background: </strong>Polarized transilluminating dermoscopy is a novel technique that can be used to diagnose hair shaft disorders. The technique has been used once to describe the findings of trichothiodystrophy, but its use in other hair shaft disorders has not yet been studied.</p><p><strong>Objectives: </strong>To assess the efficacy and utility of polarized transilluminating dermoscopy (PTD) in various hair shaft disorders and describe the observations noted.</p><p><strong>Methods: </strong>Six patients with suspected hair shaft disorder were enrolled based on history and clinical examination. Trichogram, trichoscopy, and PTD were performed in all the cases, and the findings were described.</p><p><strong>Result: </strong>PTD enhances the visualization of hair shaft disorders, including pili torti, trichorrhexis nodosa, trichorrhexis invaginata, pili trianguli et canaliculi, and woolly hair. The utilization of the given method in hair analysis represents a significant advancement in the field, offering distinctive insights into the inner structures of hair shafts.</p><p><strong>Conclusion: </strong>In contrast to simple trichoscopy using a polarizing dermatoscope, PTD revealed detailed defects and was confirmatory for the diagnosis of the respective disorder.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Lipschütz Ulcers in a 13-Year-Old Girl With PFAPA Syndrome.
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-04-02 DOI: 10.1111/pde.15926
Remi Parker, Hannah Russell Johns, Crystal Pourciau
{"title":"A Case of Lipschütz Ulcers in a 13-Year-Old Girl With PFAPA Syndrome.","authors":"Remi Parker, Hannah Russell Johns, Crystal Pourciau","doi":"10.1111/pde.15926","DOIUrl":"https://doi.org/10.1111/pde.15926","url":null,"abstract":"<p><p>Lipschütz ulcers (LU), also known as reactive non-sexually related acute genital ulcerations, are an uncommon condition that primarily affects sexually inactive girls under the age of 20 years. In this report, we describe a 13-year-old female with a past medical history of periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) in early childhood who presented to the emergency department (ED) for sudden onset of genital ulcerations and labial swelling. Based on her clinical presentation, negative primary infectious workup, unresponsiveness to broad-spectrum antimicrobials, and concurrent viral infection, she was diagnosed with LU.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bibliometric Analysis of the 50 Most Cited Publications in Epidermolysis Bullosa.
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-04-01 DOI: 10.1111/pde.15912
Evelyn F Fagan, Jennifer M Fernandez, Joseph T McGrath, Erin X Wei, Mollie Oudenhoven
{"title":"Bibliometric Analysis of the 50 Most Cited Publications in Epidermolysis Bullosa.","authors":"Evelyn F Fagan, Jennifer M Fernandez, Joseph T McGrath, Erin X Wei, Mollie Oudenhoven","doi":"10.1111/pde.15912","DOIUrl":"https://doi.org/10.1111/pde.15912","url":null,"abstract":"<p><p>Epidermolysis bullosa (EB) is a group of inherited skin disorders characterized by extreme skin fragility, leading to recurrent blistering and significant impacts on patients' quality of life. A bibliometric analysis of the 50 most-cited EB articles from the past six decades reveals that the majority of research focuses on understanding EB pathogenesis, with a growing emphasis on therapeutic interventions, particularly gene and cell-based therapies. This study highlights a shift toward clinical trials in recent years, but there is still a need for more global collaboration to address regional variations in EB and improve treatment outcomes for patients worldwide.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Updated Scoping Review of Disparities in Pediatric Atopic Dermatitis.
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-04-01 DOI: 10.1111/pde.15914
Simone Gottlieb, Krystal Madkins, Peter Lio
{"title":"An Updated Scoping Review of Disparities in Pediatric Atopic Dermatitis.","authors":"Simone Gottlieb, Krystal Madkins, Peter Lio","doi":"10.1111/pde.15914","DOIUrl":"https://doi.org/10.1111/pde.15914","url":null,"abstract":"<p><strong>Background/objectives: </strong>Health disparities are preventable differences in various aspects of health and encompass a wide range of inequitable outcomes experienced by marginalized patient populations. The objective of this systematic scoping review was to provide an updated summary of published research on disparities within pediatric atopic dermatitis (AD) in the United States.</p><p><strong>Methods: </strong>We performed a systematic search of full studies and abstracts according to PRISMA guidelines. Searches were developed with and performed by a medical librarian on various electronic databases for studies published from January 2021 through May 2024. Two authors independently screened titles and abstracts, followed by full-text review.</p><p><strong>Results: </strong>Fifty-three studies met our inclusion criteria, of which 49 examined disparities due to race/ethnicity, 18 due to socioeconomic factors (SES), 6 due to region/environment, 11 due to sex/gender, and 1 due to preferred language. Disparities discussed included AD prevalence, health outcomes, and access to health care.</p><p><strong>Conclusion: </strong>With an increasing focus on health disparities research, particularly within the context of the COVID-19 pandemic, an update on disparities within pediatric AD is needed. Examining the results of these studies can help point us to interventions that aim to reduce disparities and allow us to identify current knowledge gaps in disparities within pediatric AD.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Generalized Exanthematous Pustulosis Associated With Human Parvovirus B19 in an 11-Year-Old Girl.
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-04-01 DOI: 10.1111/pde.15928
Saniye Yasemin Yilmaz, İlknur Külhaş Çelik, Gülsüm Alkan, İsmail Harmankaya, Hasibe Artaç
{"title":"Acute Generalized Exanthematous Pustulosis Associated With Human Parvovirus B19 in an 11-Year-Old Girl.","authors":"Saniye Yasemin Yilmaz, İlknur Külhaş Çelik, Gülsüm Alkan, İsmail Harmankaya, Hasibe Artaç","doi":"10.1111/pde.15928","DOIUrl":"https://doi.org/10.1111/pde.15928","url":null,"abstract":"<p><p>Acute generalized exanthematous pustulosis (AGEP) is a severe adverse cutaneous reaction characterized by the rapid development of nonfollicular sterile pustules on an erythematous base. AGEP is drug induced in 90% of cases but has been associated with viral infections. This report describes a rare case of AGEP induced by parvovirus B19 infection in a pediatric patient.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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