Pediatric Dermatology最新文献_第2页

Long-Term Outcomes of Prepubertal-Onset Vulvar Lichen Sclerosus. 青春期前外阴硬化地衣的远期预后。

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-10-13 DOI: 10.1111/pde.70056

Alexandra Savage, Vera Y Miao, Gayle Fischer, Matthew Merriman, Kylie-Ann Mallitt, Rebecca B Saunderson

{"title":"Long-Term Outcomes of Prepubertal-Onset Vulvar Lichen Sclerosus.","authors":"Alexandra Savage, Vera Y Miao, Gayle Fischer, Matthew Merriman, Kylie-Ann Mallitt, Rebecca B Saunderson","doi":"10.1111/pde.70056","DOIUrl":"https://doi.org/10.1111/pde.70056","url":null,"abstract":"Background: Vulvar lichen sclerosus (VLS) is a chronic inflammatory dermatosis affecting the vulvar and perianal skin. VLS has a bimodal age of onset, in pre-pubertal and post-menopausal age groups. Long-term outcomes of pre-pubertal VLS are unclear. This study aimed to establish the long-term disease activity, factors that influence disease progression, and the physical and psychological complications of pediatric VLS persisting into adulthood.Methods: A cohort study was conducted in women diagnosed with VLS pre-menarche. A retrospective chart review of 135 case records was completed. The remaining data collection occurred prospectively through (i) study questionnaires, including quality of life as assessed by the Vulvar Quality of Life Index (VQLI), and (ii) dermatologist assessments.Results: Of 135 patients screened, 68 were included. The mean age of diagnosis was 7.5 years, and the mean duration of follow-up was 12.8 years. 62% of cases achieved remission. Of patients who were adherent to treatment, 92.3% achieved remission, compared to 56.6% of patients who were non- or partially adherent. Adherence declined from menarche into early adolescence. Patients who were adherent had 60% fewer structural abnormalities. In addition, VQLI scores indicated significantly better quality of life with adherence (mean = 1.6/45) compared to partially or non-adherence (mean = 5.2/45).Conclusions: This study informs clinicians of the long-term prognosis of VLS diagnosed pre-pubertally: 62% of patients achieved remission, and the rates of remission were higher in those who adhered to treatment. Structural changes and scarring were reduced in those who adhered to treatment.","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comorbidities of Pediatric Patients With Hidradenitis Suppurativa in the Emergency Department Setting: A Cross-Sectional Study. 急诊小儿化脓性汗腺炎的合并症：一项横断面研究

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-10-13 DOI: 10.1111/pde.70054

Rahwa Hailemichael, Sydney A Martin, Austin Hwang, Julia M Riley, Kelsey S Flood, Ziyou Ren

引用次数: 0

Early Magnetic Resonance Imaging as a Screen for Sturge-Weber Syndrome-Related Seizures in Infants With Upper-Facial Capillary Malformations. 早期磁共振成像作为筛查斯特奇-韦伯综合征相关癫痫发作的婴儿上面部毛细血管畸形。

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-10-13 DOI: 10.1111/pde.70032

Mia A Mologousis, Racquel A Bitar, Anna L Pinto, Joanne M Rispoli, Marilyn G Liang

{"title":"Early Magnetic Resonance Imaging as a Screen for Sturge-Weber Syndrome-Related Seizures in Infants With Upper-Facial Capillary Malformations.","authors":"Mia A Mologousis, Racquel A Bitar, Anna L Pinto, Joanne M Rispoli, Marilyn G Liang","doi":"10.1111/pde.70032","DOIUrl":"https://doi.org/10.1111/pde.70032","url":null,"abstract":"Background: Upper-facial capillary malformation (CM) may be concerning for Sturge-Weber syndrome (SWS). Use of screening magnetic resonance imaging (MRI) for neuroradiographic findings of SWS is controversial. MRI within a few months of life may allow for prompt reassurance, preventive treatments, and avoidance of contrast and sedation. However, false-negative MRI before 1 year of age has been reported. We examined the ability of early MRI to predict seizure development in infants with upper-facial CM.Methods: Infants with forehead or temple CM presenting to the Sturge-Weber Clinic at Boston Children's Hospital from 2012 to 2022 were identified. The records were reviewed for clinical features and for findings from MRI performed before 1 year of age (MRI 1) and repeated around or after 2 years of age (MRI 2). Patients with seizures before MRI 1 or with a diagnosis of nevus simplex were excluded.Results: Thirty-three patients with forehead or temple CM without seizures before MRI 1 were identified. MRI 1 was abnormal in 20/33 and normal in 13/33. Fourteen of 20 patients with abnormal MRI 1 developed seizures. Of the 13 patients with normal MRI 1, 11 underwent MRI 2. In patients with MRI 2, 3/11 developed SWS-related abnormalities, but none (0/11) developed seizures. The remaining 2 patients with normal MRI 1 also did not develop seizures. Mean follow-up age was 6.1 years (0.83-15 years).Conclusion: Early, high-quality non-contrast 3 T MRI may screen for seizure development in infants with upper-facial CM.","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examining the Impacts of Social Drivers of Health and Adverse Childhood Experiences in Children With Dermatological Disease: Part I: An Update and Review for Pediatric Dermatologists. 检查皮肤病儿童健康和不良童年经历的社会驱动因素的影响：第一部分：儿科皮肤科医生的更新和回顾。

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-10-13 DOI: 10.1111/pde.70050

Toyosi Oluwole, Jeanette Zambito, Sarah J Coates

{"title":"Examining the Impacts of Social Drivers of Health and Adverse Childhood Experiences in Children With Dermatological Disease: Part I: An Update and Review for Pediatric Dermatologists.","authors":"Toyosi Oluwole, Jeanette Zambito, Sarah J Coates","doi":"10.1111/pde.70050","DOIUrl":"https://doi.org/10.1111/pde.70050","url":null,"abstract":"Social drivers of health (SDH) are defined as the conditions in which people are born, live, learn, work, play, and age. These non-medical factors affect a wide range of health-related behaviors and outcomes and can be predictive of the development of chronic medical conditions. Moreover, having one or more negative SDH can influence the availability and feasibility of treatment options, as well as response to treatment. While research has increasingly shown that addressing SDH is critical to achieving optimal health outcomes for all patients across multiple fields of medicine, the field of dermatology is trailing behind other specialties in identifying and addressing SDH. Children face special barriers to care due to their relative inability to advocate for themselves and their increased likelihood of experiencing poverty, food insecurity, and housing insecurity in the United States. Many children also experience adverse childhood experiences (ACEs), and these traumatic stressors are associated with the development of chronic health conditions and diminished life expectancy. Numerous studies have demonstrated the effects of SDH and ACEs on the prevalence of and outcomes for common pediatric skin conditions, including atopic dermatitis, psoriasis, hidradenitis suppurativa, and acne vulgaris. Pediatric dermatologists should learn how to identify and screen for social risk in the clinical environment and know how to address these effectively in their practice to improve the health of all children.","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Agminated, Eruptive Nevi in Patients With a History of Langerhans Cell Histiocytosis. 有朗格汉斯细胞组织细胞增多症病史的患者的急性、爆发性痣。

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-10-09 DOI: 10.1111/pde.70040

Maria Fernanda Alvarez-Alatriste, Andrea Gallardo-Villamil, Cristian M Salgado-Flores, Carrie C Coughlin, Liza Siegel, Leah Lalor, Kelly M Cordoro, Christine Wong, María Teresa García-Romero

引用次数: 0

Quality of Life in Pediatric Hidradenitis Suppurativa: A Cross-Sectional Study. 儿童化脓性汗腺炎的生活质量：一项横断面研究。

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-10-09 DOI: 10.1111/pde.70042

Charles B Lau, Eric Xia, Lisa Y Shen

引用次数: 0

Connecting Families to Care: Nonprofit Wig Resources for Children. 连接家庭与关怀：非营利性儿童假发资源。

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-10-09 DOI: 10.1111/pde.70075

Adaora Ewulu, Theresa Chikodi Ohaya, Natasha Mesinkovska, Maria Gnarra Buethe

引用次数: 0

Teaching Pediatric Dermatology to Primary Care Residents: Valued in Principle, Undervalued in Practice. 初级保健住院医师儿科皮肤病学教学：原则被重视，实践被低估。