局部Ruxolitinib成功治疗小儿局部睡眠不足。

IF 1.2 4区医学 Q3 DERMATOLOGY

Pediatric Dermatology Pub Date : 2025-07-13 DOI:10.1111/pde.16025

Grace Rabinowitz, Nicholas Gulati, Saakshi Khattri, Justine Fenner

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引用次数: 0

摘要

小儿麻痹症是一种罕见的疾病，其特征是皮肤和基础结构的纤维化。局部、简单疾病的一线治疗通常是使用高效的局部类固醇。关于局部顽固性疾病治疗的文献很少。我们报告一例活检证实的睡眠不足的17岁女性，在氯倍他索软膏治疗失败后，局部使用1.5% ruxolitinib乳膏和局部使用曲安奈德显着改善。

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Localized Morphea in a Pediatric Patient Successfully Treated With Topical Ruxolitinib.

Pediatric morphea is a rare disorder characterized by fibrosis of the skin and underlying structures. First-line treatment of localized, uncomplicated disease is typically with high-potency topical steroids. Literature on the treatment of localized recalcitrant disease is sparse. We report a case of biopsy-confirmed morphea in a 17-year-old female that significantly improved with topical ruxolitinib 1.5% cream and intralesional triamcinolone after treatment with clobetasol ointment failed.

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来源期刊

Pediatric Dermatology 医学-皮肤病学

CiteScore

3.20

自引率

6.70%

发文量

269

审稿时长

1 months

期刊介绍： Pediatric Dermatology answers the need for new ideas and strategies for today''s pediatrician or dermatologist. As a teaching vehicle, the Journal is still unsurpassed and it will continue to present the latest on topics such as hemangiomas, atopic dermatitis, rare and unusual presentations of childhood diseases, neonatal medicine, and therapeutic advances. As important progress is made in any area involving infants and children, Pediatric Dermatology is there to publish the findings.