静脉注射免疫球蛋白治疗青少年皮肌炎患者血栓栓塞风险

IF 1.2 4区医学 Q3 DERMATOLOGY

Pediatric Dermatology Pub Date : 2025-05-01 Epub Date: 2025-01-09 DOI:10.1111/pde.15865

Lais Lopes Almeida Gomes, Genevieve S Silva, Hallie A Carol, Sweta Subhadarshani, Beth H Rutstein, Katharina S Shaw

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引用次数: 0

摘要

这项单机构回顾性队列研究评估了静脉注射免疫球蛋白（IVIg）治疗的青少年皮肌炎（JDM）患者血栓栓塞事件（TE）的风险。我们发现接受IVIg治疗的JDM患者与未接受IVIg治疗的患者TE的发生率没有差异；两组患者均无TEs。两组JDM患者的其他凝血危险因素水平相匹配，如活动受限期和激素避孕药的使用。这项研究支持了在成年糖尿病人群中越来越多的证据，表明IVIg没有显著增加TE的风险，并表明在JDM中TE的发生率很低。

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Thromboembolic Risk in Juvenile Dermatomyositis Patients Treated With Intravenous Immunoglobulin.

This single-institution retrospective cohort study evaluates the risk of thromboembolic events (TE) in patients with juvenile dermatomyositis (JDM) treated with intravenous immunoglobulin (IVIg). We found no difference in the occurrence of TE in JDM patients treated with IVIg as compared to those without IVIg exposure; both cohorts had no TEs. Patients in both JDM cohorts had matched levels of other clotting risk factors, such as periods of limited mobility and hormonal contraceptive use. This research supports the growing body of evidence in the adult DM population demonstrating no significantly increased risk of TE attributable to IVIg and suggests that the occurrence of TE in JDM is low.

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来源期刊

Pediatric Dermatology 医学-皮肤病学

CiteScore

3.20

自引率

6.70%

发文量

269

审稿时长

1 months

期刊介绍： Pediatric Dermatology answers the need for new ideas and strategies for today''s pediatrician or dermatologist. As a teaching vehicle, the Journal is still unsurpassed and it will continue to present the latest on topics such as hemangiomas, atopic dermatitis, rare and unusual presentations of childhood diseases, neonatal medicine, and therapeutic advances. As important progress is made in any area involving infants and children, Pediatric Dermatology is there to publish the findings.