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Significant improvement of a nevus spilus-type congenital melanocytic nevus with oral selumetinib. 口服赛鲁米替尼能明显改善蜘蛛痣型先天性黑素细胞痣。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 Epub Date: 2024-06-17 DOI: 10.1111/pde.15666
R Berna, T Hasbun, D Adams, A T Moon, J R Treat
{"title":"Significant improvement of a nevus spilus-type congenital melanocytic nevus with oral selumetinib.","authors":"R Berna, T Hasbun, D Adams, A T Moon, J R Treat","doi":"10.1111/pde.15666","DOIUrl":"10.1111/pde.15666","url":null,"abstract":"<p><p>Giant congenital melanocytic nevi (GCMN) can be cosmetically significant and can lead to melanoma. There is no standard pharmacologic treatment for GCMN. We present the case of an 8-year-old female with kaposiform lymphangiomatosis caused by an NRAS mutation whose nevus spilus-type GCMN improved on oral selumetinib.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141420246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Solitary ulcerated nodule on the scalp in an 11-year-old girl. 一名 11 岁女孩头皮上的孤立性溃疡结节。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 Epub Date: 2024-07-16 DOI: 10.1111/pde.15613
Sara Sadeghi, Emma F Johnson, Sindhuja Sominidi Damodaran, Setu Mittal, Nessa Aghazadeh Mohandesi
{"title":"Solitary ulcerated nodule on the scalp in an 11-year-old girl.","authors":"Sara Sadeghi, Emma F Johnson, Sindhuja Sominidi Damodaran, Setu Mittal, Nessa Aghazadeh Mohandesi","doi":"10.1111/pde.15613","DOIUrl":"10.1111/pde.15613","url":null,"abstract":"","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141620658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What Is Nevus Simplex? 什么是单纯性痣？
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 DOI: 10.1111/pde.15762
{"title":"What Is Nevus Simplex?","authors":"","doi":"10.1111/pde.15762","DOIUrl":"https://doi.org/10.1111/pde.15762","url":null,"abstract":"<p><p>Nevus simplex, also called a \"salmon patch\" or \"stork bite,\" is a special mark that some babies are born with. It is very common and doesn't hurt.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142351626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neonatal nasal necrosis: Case series and brief review. 新生儿鼻坏死：病例系列和简要回顾。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 Epub Date: 2024-03-08 DOI: 10.1111/pde.15600
Jamie L Karch, David Grand, Ariana G Diaz, Leah Belazarian, Julianne A Mann
{"title":"Neonatal nasal necrosis: Case series and brief review.","authors":"Jamie L Karch, David Grand, Ariana G Diaz, Leah Belazarian, Julianne A Mann","doi":"10.1111/pde.15600","DOIUrl":"10.1111/pde.15600","url":null,"abstract":"<p><p>There is limited information available on pressure-related neonatal nasal injuries. We present three neonates born with erythema and purpura of the nasal tip that subsequently ulcerated, then evolved into a thick eschar. Each healed well with conservative management but left behind significant scarring. The sharp demarcation and location of the lesions were suggestive of hypoxic tissue damage akin to halo scalp ring alopecia. Further investigation is necessary to elucidate the etiology and optimal management of this condition.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140065630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parent experiences during delivery, postpartum, and adoption of children with congenital melanocytic nevi. 先天性黑素细胞痣患儿父母在分娩、产后和领养期间的经历。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 Epub Date: 2024-08-28 DOI: 10.1111/pde.15728
Yuliya Kozina, Kendrick J Williams, Mary C Politi, Ilona J Frieden, Carrie C Coughlin
{"title":"Parent experiences during delivery, postpartum, and adoption of children with congenital melanocytic nevi.","authors":"Yuliya Kozina, Kendrick J Williams, Mary C Politi, Ilona J Frieden, Carrie C Coughlin","doi":"10.1111/pde.15728","DOIUrl":"10.1111/pde.15728","url":null,"abstract":"<p><strong>Background/aims: </strong>Congenital melanocytic nevi (CMN) are often unexpected discoveries at time of childbirth or adoption. Understanding how parents/guardians cope with these visible birthmarks can help clinicians better care for children and their families. Using qualitative methods, we sought to categorize early family responses to CMN and identify approaches to better engage with parents early in their child's life.</p><p><strong>Methods: </strong>Semi-structured interviews were conducted within a broader study on shared decision making for families with children with CMN. Discussions included information on birth and early life experiences. Data was dual-coded, inductively and deductively, and analyzed with the Parker and Endler framework exploring emotion-, task-, and avoidance-oriented coping.</p><p><strong>Results: </strong>Fifteen parents of 13 children were interviewed. Parents described all three categories of coping. Emotions ranged from guilt, to neutrality, to positive responses seeing their child's CMN. Stress was lower in families with prior knowledge of CMN. Dermatology referral provided an opportunity for learning, but also triggered worry for some families.</p><p><strong>Conclusions: </strong>Parents process and react to the diagnosis of CMN with a range of emotions and coping styles. Dermatologists can utilize open-ended questions to understand family emotions and provide families with tailored knowledge and resources. Early discussion of the diagnosis and family education are important support tools.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142093667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Social media use among adolescents with acne: A cross-sectional survey study. 痤疮青少年使用社交媒体的情况：一项横断面调查研究。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 Epub Date: 2024-05-09 DOI: 10.1111/pde.15651
Cyrelle F Finan, Phoenix Leon, Lynn Midani, Deirdre A Hill, Aimee C Smidt
{"title":"Social media use among adolescents with acne: A cross-sectional survey study.","authors":"Cyrelle F Finan, Phoenix Leon, Lynn Midani, Deirdre A Hill, Aimee C Smidt","doi":"10.1111/pde.15651","DOIUrl":"10.1111/pde.15651","url":null,"abstract":"<p><p>Social media is increasingly used by patients for the management of skin conditions like acne, despite the potential risk for low-quality information. This study surveyed 45 participants between the ages of 12 and 17 years to investigate factors that could be associated with social media use among adolescents with acne. The likelihood of social media use was not significantly increased by clinical severity of acne, more severe physical barriers (greater than or equal to 20 miles to the dermatology clinic), more severe temporal barriers (waiting 12 or more weeks for a first dermatology appointment), or worsened quality of life (assessed via the Skindex-Teen score). This study increases understanding of adolescents' social media behaviors, particularly as a way to seek information for skin conditions like acne.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140898728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics of board-certified pediatric dermatologists accepting Medicaid. 接受医疗补助的经委员会认证的儿科皮肤科医生的特点。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 Epub Date: 2024-06-17 DOI: 10.1111/pde.15656
Madeleine Tessier-Kay, Eric Beltrami, Shivani Sinha, Hao Feng
{"title":"Characteristics of board-certified pediatric dermatologists accepting Medicaid.","authors":"Madeleine Tessier-Kay, Eric Beltrami, Shivani Sinha, Hao Feng","doi":"10.1111/pde.15656","DOIUrl":"10.1111/pde.15656","url":null,"abstract":"<p><p>A current shortage of pediatric dermatologists limits access to dermatologic care among the pediatric population, yet comprehensive and updated data are lacking regarding access among the pediatric Medicaid population. This cross-sectional study characterized Medicaid acceptance among actively practicing board-certified pediatric dermatologists in the United States and revealed that of the 352 physicians compiled, 275 (78.1%) accept Medicaid. Significant differences in Medicaid acceptance status were observed based on practice type, region of practice, practice county median household income, and density of pediatric dermatologists. While the majority of practicing board-certified pediatric dermatologists accept Medicaid, our findings suggest that differences in access to Medicaid-accepting pediatric dermatologists exist based on practice type, geographic location, and density of pediatric dermatologists per county.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141420282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Online, home-based dystrophic epidermolysis bullosa registry. 在线家庭萎缩性表皮松解症登记。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 Epub Date: 2024-06-28 DOI: 10.1111/pde.15682
Vaishali Mittal, Jaron Nazaroff, Edward Eid, Shufeng Li, Eleni Linos, Anthony Oro, Jean Y Tang
{"title":"Online, home-based dystrophic epidermolysis bullosa registry.","authors":"Vaishali Mittal, Jaron Nazaroff, Edward Eid, Shufeng Li, Eleni Linos, Anthony Oro, Jean Y Tang","doi":"10.1111/pde.15682","DOIUrl":"10.1111/pde.15682","url":null,"abstract":"<p><p>Genetic testing is the gold standard for diagnosing different epidermolysis bullosa (EB) subtypes; however, testing rates are low. We conducted a pilot study to test feasibility of a novel, home-based registry that involved patients with EB submitting self-reported clinical symptoms using secure, online surveys (REDCap) and submitting buccal swabs for exome sequencing of EB-related genes (GeneDx). In total, 50 EB participants were enrolled, with an average age of 17 years and an average distance of 198 miles from EB specialty centers. All buccal swabs (N = 24) provided sufficient DNA for sequencing without causing mucosal trauma and 80% of participants were found to have pathogenic variants in COL7A1, the gene mutated in DEB. Participants with recessive dystrophic EB (RDEB) reported a higher prevalence of esophageal dilations (65.7% vs. 0%, p = .009) and mitten deformities of the feet (57.1% vs. 0%, p = .047) compared to non-RDEB participants.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141470048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric cutaneous Crohn disease: A case series of 89 patients and review. 小儿皮肤克罗恩病：89 例患者的系列病例及回顾。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 Epub Date: 2024-07-16 DOI: 10.1111/pde.15689
Grace E McKay, Lynn Liu, Katharina S Shaw, Hadir Shakshouk, Michael J Murphy, William Damsky, Alex G Ortega-Loayza, Avrom S Caplan, Lisa M Arkin, Bridget E Shields
{"title":"Pediatric cutaneous Crohn disease: A case series of 89 patients and review.","authors":"Grace E McKay, Lynn Liu, Katharina S Shaw, Hadir Shakshouk, Michael J Murphy, William Damsky, Alex G Ortega-Loayza, Avrom S Caplan, Lisa M Arkin, Bridget E Shields","doi":"10.1111/pde.15689","DOIUrl":"10.1111/pde.15689","url":null,"abstract":"<p><strong>Background: </strong>Cutaneous (or \"Metastatic\") Crohn disease (CCD) is a rare and underrecognized disease characterized by cutaneous granulomatous inflammation. We describe patient demographics, clinical characteristics, histology, and treatment of 89 pediatric cases of CCD, including 78 previously reported and 11 new cases seen at four academic institutions. We emphasize the efficacy of biologic mono- and dual therapy.</p><p><strong>Methods: </strong>PubMed identified cases using keywords including \"metastatic Crohn disease\" and \"cutaneous Crohn disease\". Patients were identified by retrospective review of the electronic health record including histopathologic diagnosis consistent with CCD. Chart review collected demographic, clinical, and histologic data.</p><p><strong>Results: </strong>Most pediatric patients with CCD are male 55% (49/89), present with edema (73/89, 82%) and erythema (47/89, 53%) of the genitals (33/49, 67%), and have intestinal Crohn disease (69/89, 78%). Oral corticosteroids (53/75, 71%) and metronidazole (29/75, 39%) are the most frequently prescribed medications. Of the 17 patients treated with tumor necrosis factor (TNF)-blockade, 94% (16/17) had partial or total clearance. Ustekinumab resulted in clearance of cutaneous disease in two patients (2/3, 67%) and partial clearance in one patient (1/3, 33%). Two cases achieved total clearance with the use of dual biologic therapy defined as the use of two biologic therapies with differing mechanisms of action or the use of a biologic therapy and small molecule inhibitor.</p><p><strong>Conclusions: </strong>TNF blockade is an effective treatment for pediatric CCD, and interleukin-12/23 inhibitors may be similarly effective. Consideration of dual biologic therapy may be useful in pediatric patients requiring discordant therapies for their intestinal and cutaneous CD.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141620657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A curious case of blistering dermatitis in a child. 一例奇特的儿童水疱性皮炎病例。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2024-09-01 Epub Date: 2024-06-17 DOI: 10.1111/pde.15634
Neha Kinariwalla, Sonora Yun, Andrea R Waldman, Gary S Edelstein, Maria C Garzon, Christine T Lauren
{"title":"A curious case of blistering dermatitis in a child.","authors":"Neha Kinariwalla, Sonora Yun, Andrea R Waldman, Gary S Edelstein, Maria C Garzon, Christine T Lauren","doi":"10.1111/pde.15634","DOIUrl":"10.1111/pde.15634","url":null,"abstract":"","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141420279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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