Pediatric Dermatology最新文献_第7页

Evaluating the Readability of the iPledge Comprehension Assessment and its Impact on Isotretinoin Accessibility. 评估 iPledge 理解力评估的可读性及其对异维A酸可及性的影响。

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-09-23 DOI: 10.1111/pde.15765

Peter Baek, Nidhi Shah, A Yasmine Kirkorian

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Odontogenic Cutaneous Sinus Tract in a 12-Year-Old Patient: Case Report. 一名 12 岁患者的牙源性皮肤窦道：病例报告。

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-11-18 DOI: 10.1111/pde.15808

Indrė Kaučikaitė, Greta Lodienė, Neringa Skučaitė

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Understanding and Managing Vulvar Psoriasis in Girls: Findings From a Cohort Study. 了解和治疗女孩外阴银屑病：一项队列研究的发现

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-11-26 DOI: 10.1111/pde.15816

Michelle Wu, Gayle Fischer

{"title":"Understanding and Managing Vulvar Psoriasis in Girls: Findings From a Cohort Study.","authors":"Michelle Wu, Gayle Fischer","doi":"10.1111/pde.15816","DOIUrl":"10.1111/pde.15816","url":null,"abstract":"Background/objectives: Pediatric vulvar psoriasis in girls is under-recognized and under-treated due to its nonspecific clinical appearance. This paper aims to describe the signs and symptoms of pediatric vulvar psoriasis and treatment strategies used by our group.Methods: A retrospective cohort study was undertaken at a private pediatric dermatology referral practice from January 2016 to December 2022. Clinical data were prospectively collected and recorded in an online patient database. Treatment regimens were individualized and titrated to clinical response.Results: In 100 girls with vulvar psoriasis, the most common presentation was an erythematous vulvar eruption (97%) which was well-demarcated in 52% of children and appeared as a plaque in one-fourth. The perianal skin was involved in 48% of cases. Extragenital psoriasis was present in 69% of patients. Most children responded to initial induction treatment with moderate-potency topical corticosteroid ointment followed by maintenance with topical tar solution. Systemic treatment was not required for purely vulvar psoriasis compared with 3% of children with extragenital psoriasis.Conclusion: Vulvar psoriasis in girls presents as a chronic erythematous vulvitis, with perianal involvement in half the cases, but without vaginitis. It is a remitting and relapsing skin condition that requires long-term topical management.","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"273-277"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142731553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Distinctive Plaque in a Tuberous Sclerosis Patient. 结节性硬化症患者的特殊斑块。

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2025-01-08 DOI: 10.1111/pde.15776

Hitaishi Mehta, Kumari Sweta Leena Patra, Abhay Gupta, Debajyoti Chatterjee, Anuradha Bishnoi

引用次数: 0

Camp Wonder Provides Short-Term Health-Related Quality of Life Benefits for Participants With Chronic Skin Disease.

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2025-02-05 DOI: 10.1111/pde.15896

Mani K Woodward, Rishi Seshadri, Thatcher Healy, Sabra Leitenberger, Julie Dhossche

{"title":"Camp Wonder Provides Short-Term Health-Related Quality of Life Benefits for Participants With Chronic Skin Disease.","authors":"Mani K Woodward, Rishi Seshadri, Thatcher Healy, Sabra Leitenberger, Julie Dhossche","doi":"10.1111/pde.15896","DOIUrl":"10.1111/pde.15896","url":null,"abstract":"Introduction: Chronic skin diseases in children can significantly impair their quality of life (QOL) due to physical discomfort and psychosocial challenges. Disease-focused summer camps, like Camp Wonder (CW), offer a supportive environment for children to engage in activities and build friendships, potentially improving their QOL.Methods: This prospective cohort study evaluated the short-term QOL benefits of CW as measured by the Children's Dermatology Life Quality Index (CDLQI). Data were collected from 58 camp participants aged 8-17 years. The CDLQI was administered on the first and last days of CW. The paired sample t-test was used to compare pre-camp and post-camp CDLQI scores. A multiple linear regression analysis examined predictors of QOL improvement, including age, diagnosis category, sex, and initial CDLQI severity.Results: CW participants showed significant improvements in total CDLQI scores (mean change = -3.8 points, p < 0.0001) and in all constituent domains. Participants with \"very large\" initial QOL impacts experienced an average reduction of 8.4 points, while those with \"extremely large\" impacts had a reduction of 15.3 points relative to the reference group. Age, sex, and diagnosis were not significant predictors of QOL changes.Conclusion: CW provides significant short-term QOL benefits, particularly for children with severe impairments due to chronic skin disease. These findings suggest that summer camp experiences may be useful as part of a comprehensive care strategy, especially for pediatric patients with severe QOL impacts.","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"240-244"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Missense Variant Affecting the N-Terminal Domain of the Laminin-332 β3 Chain Results in a Distinct Form of Junctional Epidermolysis Bullosa With Altered Granulation Tissue Response and No New Blistering: A Second Family Report. 影响层粘连蛋白-332 β3 链 N 端域的缺义变异导致一种不同形式的交界性表皮松解症，其肉芽组织反应改变，但无新的水疱：第二个家族报告

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-10-23 DOI: 10.1111/pde.15764

Marina Goldoni, Barbara Torres, Maurizio Pettinato, Alessia Gennaro, Tommaso Biagini, Angelo Giuseppe Condorelli, Rosanna Monetta, Tommaso Mazza, Laura Bernardini, Teresa Mattina

{"title":"A Missense Variant Affecting the N-Terminal Domain of the Laminin-332 β3 Chain Results in a Distinct Form of Junctional Epidermolysis Bullosa With Altered Granulation Tissue Response and No New Blistering: A Second Family Report.","authors":"Marina Goldoni, Barbara Torres, Maurizio Pettinato, Alessia Gennaro, Tommaso Biagini, Angelo Giuseppe Condorelli, Rosanna Monetta, Tommaso Mazza, Laura Bernardini, Teresa Mattina","doi":"10.1111/pde.15764","DOIUrl":"10.1111/pde.15764","url":null,"abstract":"Junctional epidermolysis bullosa (JEB) is a rare genodermatosis characterized by fragility of the skin and mucous membranes due to alterations in the dermal epidermal junction. This condition manifests as mechanically induced bullous lesions that heal with hypertrophic granulation tissue and/or atrophic scars. Here, we report two brothers carrying a homozygous LAMB3 missense variant, p.Gly254Asp, which affects the N-terminal end of the laminin-332 (LM332) β3 chain, previously described in another JEB family sharing a common ethnic origin and LAMB3 haplotype with the siblings reported here. Moreover, all affected patients with p.Gly254Asp mutation from both families exhibits a distinct phenotype consisting of a few localized long-standing skin lesions characterized by excessive granulation tissue formation or keloid scars, without new blistering, and associated with amelogenesis imperfecta. Our patients also showed nail dystrophy, expanding the phenotypic spectrum and confirming the peculiar role of the N-terminal end of the β3 chain in regulating the granulation tissue response associated with the wound healing process.","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"410-412"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142505508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Guest Editor's Note.

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-03-01 DOI: 10.1111/pde.15861

Brittany G Craiglow

引用次数: 0

Pathophysiology of Alopecia Areata in the Pediatric Patient. 小儿脱发症的病理生理学。

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-03-01 DOI: 10.1111/pde.15842

Madeline H Fitzhugh, Jacob G Hansen, Ali Jabbari, Kristen G Berrebi

引用次数: 0

What is acne?

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-03-01 DOI: 10.1111/pde.15934

引用次数: 0

Live Attenuated Vaccine Administration in Children Treated With Methotrexate or Dupilumab. 甲氨蝶呤或杜匹单抗治疗儿童减毒活疫苗的应用

IF 1.2 4区医学

Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-12-11 DOI: 10.1111/pde.15818

Julia R Hughes, Sino Mehrmal, Sana Habib, Howard L Williams, Elaine C Siegfried

{"title":"Live Attenuated Vaccine Administration in Children Treated With Methotrexate or Dupilumab.","authors":"Julia R Hughes, Sino Mehrmal, Sana Habib, Howard L Williams, Elaine C Siegfried","doi":"10.1111/pde.15818","DOIUrl":"10.1111/pde.15818","url":null,"abstract":"Background and objectives: A wholesale recommendation against use of live virus vaccines in patients treated with any medication classified as an immunosuppressant has been based on global theoretical concerns rather than clinical outcomes for specific drugs.Methods: A retrospective search of electronic medical records identified patients seen by the Allergy and/or Dermatology services between 2017 and 2023 at a pediatric tertiary center who received a live attenuated vaccine during the 6 week interval prior to the first prescription for methotrexate or dupilumab until 6 weeks after the last prescription for either medication. Individual charts of identified patients were manually reviewed for evidence of adverse events.Results: The search identified 313 pediatric patients treated with dupilumab and/or methotrexate during the 7-year interval. Five of these patients received the combination measles, mumps, rubella, and varicella (MMRV) vaccine while on dupilumab and 4 while on methotrexate. Manual chart review was without evidence of adverse events for up to 6 months after immunization.Conclusions: This retrospective search identified a small number of pediatric patients immunized with the live attenuated MMRV vaccine during concomitant treatment with dupilumab or methotrexate. No associated adverse events were identified. Further investigation is needed to establish the safety and efficacy of live vaccines in patients treated with these immunomodulating agents.","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"284-288"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0