Pediatric Dermatology最新文献

{"title":"Correction to \"Impact of the Society for Pediatric Dermatology Mentorship Award Program on Careers in Pediatric Dermatology: Workforce Implications\".","authors":"","doi":"10.1111/pde.16048","DOIUrl":"https://doi.org/10.1111/pde.16048","url":null,"abstract":"","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neonatal Inflammatory Skin and Bowel Disease 1 (NISBD1): A Case of ADAM17 Homozygous Mutation.","authors":"Hannah R Chang, Megan Bannon, Chloe Opper, Anne Slavotinek, Ghada Hijazi, Kimberly M Widmeyer, Erinn S Kellner, Mariam Iqneibi, Cheryl Bayart, Kalyani S Marathe, Catherine Bridges","doi":"10.1111/pde.70028","DOIUrl":"https://doi.org/10.1111/pde.70028","url":null,"abstract":"<p><p>Neonatal inflammatory skin and bowel disease 1 (NISBD1) is a rare autosomal recessive disorder caused by mutations in ADAM17, characterized by chronic diarrhea, failure to thrive, rash, and recurrent bacterial infections. Cutaneous manifestations include the presence of a collodion membrane at birth, diffuse scaly erythematous patches and thin plaques, evanescent pustules, and/or erythroderma. We present a case of a 6-week-old full-term male with a diffuse red, focally eroded, pustular eruption in association with chronic diarrhea and failure to thrive. Genetic testing identified a novel, homozygous pathogenic ADAM17 variant, p.(Glu150=) (GAG > GAA): c.450G > A, disrupting the splice donor site and confirming the diagnosis of NISBD1.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145086614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond the Skin: A Patient-Informed Vision for Integrated Vitiligo Care.","authors":"Shahnawaz Towheed","doi":"10.1111/pde.70029","DOIUrl":"https://doi.org/10.1111/pde.70029","url":null,"abstract":"","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LUMBAR Syndrome State-Of-The-Art Review: Insights Into a Rare and Complex Condition.","authors":"Bianca Martin, Jordan K Bui, Alleana Corpin, Dawn H Siegel, Denise W Metry","doi":"10.1111/pde.70024","DOIUrl":"https://doi.org/10.1111/pde.70024","url":null,"abstract":"<p><p>LUMBAR syndrome is a rare condition with natural history and long-term outcomes that have not been well described. This acronym represents the constellation of features associated with the condition: Lower body hemangiomas with Urogenital anomalies and Ulceration, spinal cord Malformations, Bony defects of the spine and lower extremities, and Anorectal, Arterial, and/or Renal anomalies. The associated infantile hemangioma is the most notable feature, which occurs in a segmental pattern affecting the lower half of the body. Recent publications have described the clinical features of LUMBAR syndrome, its overlap with other lower body syndromes, and, notably, a landmark paper establishing diagnostic criteria through Delphi consensus. This paper aims to provide a comprehensive review of the clinical features, diagnostic criteria, pathophysiology, treatment options, and outcomes associated with LUMBAR syndrome.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Koolungar (Children) Moorditj (Strong) Healthy Skin Project Part I: Conducting First Nations Research in Pediatric Dermatology.","authors":"Bernadette M Ricciardo, Jacinta Walton, Noel Nannup, Dale Tilbrook, Heather-Lynn Kessaris, Ainslie Poore, Taleah Ugle, Carol Michie, Brad Farrant, Cheryl Bridge, Kelli McIntosh, S Prasad Kumarasinghe, Asha C Bowen","doi":"10.1111/pde.70018","DOIUrl":"https://doi.org/10.1111/pde.70018","url":null,"abstract":"<p><p>Integrating First Nations knowledge systems and Western research methodologies recognizes the strength, experience, and insight of First Nations peoples in addressing health issues in their communities. In research, this includes projects being led by First Nations Elders and peoples, including First Nations researchers in the team, and collecting data in ways that reflect First Nations ways of knowing, being, and doing. In this paper, we reflect upon the Koolungar (children) Moorditj (strong) Healthy Skin Project; operational in Perth and Bunbury, Western Australia, Australia, where the traditional custodians are the Noongar Aboriginal people. This Aboriginal Elder co-designed project is presented as a case study to illustrate the practical use of The Kids Research Institute Australia Standards for the Conduct of Aboriginal Health Research, in striving towards best practice in Aboriginal pediatric dermatology research. It leads into The Koolungar (children) Moorditj (strong) Healthy Skin Project Part II manuscript, in which we present cross-sectional studies of Aboriginal children attending community skin screening weeks.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment Strategies for Pediatric Trichotillomania: State-of-the-Art Review on Progress and Persistent Challenges.","authors":"Sheila Sharifi, Mariah Estill, Lea Tordjman, Sarah H Millan, Jessica X Ouyang","doi":"10.1111/pde.70014","DOIUrl":"https://doi.org/10.1111/pde.70014","url":null,"abstract":"<p><p>Trichotillomania (TTM) is a condition characterized by recurrent hair pulling, often resulting in hair loss and functional impairment. The disorder remains underreported in the pediatric population, despite high rates of psychiatric comorbidities. Moreover, diagnosing and treating TTM among children remains challenging due to a lack of standardized guidelines. Hence, this systematic review aims to evaluate the current treatment approaches for pediatric TTM. A comprehensive search was conducted of five databases, using the search concepts of trichotillomania, pediatric populations, and treatments/interventions. Studies were included if they (1) directly addressed the topic, (2) were of an appropriate study type (e.g., clinical trials, case-control studies, cohort studies, cross-sectional studies, or interview studies), (3) were published within the past 10 years, and (4) appeared in peer-reviewed journals published in English. Ultimately, 10 studies met our inclusion criteria, from which data were extracted and synthesized following formal quality assessment. Our results indicate that behavioral interventions, particularly habit reversal training, consistently demonstrated the greatest therapeutic benefit. Pharmacological treatments, including selective serotonin reuptake inhibitors, have been explored in various case series. Although some individuals have shown improvement, overall evidence remains insufficient to support pharmacotherapy as first-line. Alternative therapies, such as N-acetylcysteine, have also been studied, though findings are variable and require further investigation in pediatric cohorts. Our review underscores the importance of early behavioral intervention and the need for larger, controlled studies to inform standardized treatment protocols. Given the functional and psychosocial burden of TTM in youth, comprehensive management strategies are essential.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Update on \"Penile Keloid Formation Post-Circumcision: A Case Series and Review of Literature\".","authors":"Idy Tam, Lillian Sun, Lynn Woo, John Weaver, Sonal D Shah","doi":"10.1111/pde.70031","DOIUrl":"https://doi.org/10.1111/pde.70031","url":null,"abstract":"","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145054891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Koolungar (Children) Moorditj (Strong) Healthy Skin Project Part II: Skin Health in Urban-Living Australian Aboriginal Children.","authors":"Bernadette M Ricciardo, Heather-Lynn Kessaris, Noel Nannup, Dale Tilbrook, Jacinta Walton, Carol Michie, Brad Farrant, Ainslie Poore, Ingrid Amgarth-Duff, Nadia Rind, Richelle Douglas, Jodie Ingrey, Hannah Thomas, S Prasad Kumarasinghe, Jonathan R Carapetis, Asha C Bowen","doi":"10.1111/pde.70016","DOIUrl":"https://doi.org/10.1111/pde.70016","url":null,"abstract":"<p><strong>Background: </strong>Although essential for overall health and wellbeing, little is known about skin health in urban-living Australian Aboriginal children. This co-designed, research-service project aimed to describe skin health and document skin disease frequency in urban-living Aboriginal children and young people (CYP, i.e., 0-18 years) in Western Australia (WA) and investigate housing associations for skin infections.</p><p><strong>Methods: </strong>Cross-sectional studies were conducted at Aboriginal Community Controlled Health Organizations in Bunbury and Perth, WA, over 2 weeks in September-October 2022. Aboriginal CYP were eligible to participate. Questionnaire responses and examination findings were analyzed.</p><p><strong>Results: </strong>Of the 164 CYP recruited, 149 (91%) were urban-living Aboriginal CYP. Fifty-three percent (78/148) of caregivers described a dermatological concern in their child; with high caregiver diagnostic accuracy for impetigo (96%), tinea (92%), and atopic dermatitis (AD) (89%). AD (18%, 26/147), head lice (18%, 27/147), tinea (12%, 18/147) and impetigo (7%, 10/147) were most prevalent. Social housing predicted current head lice (odds ratio [OR] 4.63; 95% confidence interval [CI] 1.72-12.50), current tinea (OR 3.15; 95% CI 1.06-9.36) and ever impetigo (2.39; 95% CI 1.09-5.27). Crowded living conditions predicted ever impetigo (OR 6.28; 95% CI 2.03-19.37); whereas frequent bathing (p value 0.032) and regular swimming in a chlorinated pool (OR 0.12; 95% CI 0.02-0.95) were protective.</p><p><strong>Conclusions: </strong>We report high caregiver diagnostic accuracy for skin conditions. AD is prevalent, with undertreatment, frequent impetiginization, and sleep disturbance indicating barriers to care. Healthcare providers must advocate for improved housing, as the link between skin infections and socioeconomic disadvantage impacts overall health for urban-living Aboriginal CYP.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the Use of Melatonin in Children With Atopic Dermatitis: A Cross-Sectional Study.","authors":"Sarah Lee, Eun Jae Kim, Jennifer LeBovidge, Itohan Aigbekaen, Laura Berbert, Lynda Schneider, Tina Ho","doi":"10.1111/pde.70041","DOIUrl":"https://doi.org/10.1111/pde.70041","url":null,"abstract":"<p><strong>Background/objectives: </strong>Children with atopic dermatitis (AD) frequently experience sleep disturbances. Melatonin, an over-the-counter supplement, is increasingly used in the general pediatric population; however, its prevalence and perceived effectiveness in children with AD remain unclear.</p><p><strong>Methods: </strong>Caregivers of pediatric patients (ages 1-17 years) with physician-diagnosed AD completed surveys on melatonin use, Patient Oriented Eczema Measure (POEM), and age-appropriate sleep questionnaires.</p><p><strong>Results: </strong>Among 102 total respondents, 27.5% reported a history of melatonin use, with 10.8% using it in the past 30 days. Gummies were the most common formulation (85.7%), though brands and dosages varied widely (0.5-10 mg; median: 3 mg). 32.1% of caregivers initiated melatonin based on a healthcare professional's recommendations, while the majority initiated use independently (50.0%) or based on recommendations from friends/family (21.4%) or online resources (7.1%). Melatonin use was significantly more common among children with behavioral or psychological comorbidities compared to those without (56.3% vs. 22.1%; p = 0.012). Children ages 6-17 who used melatonin had significantly higher PROMIS Sleep Disturbance scores than nonusers (p < 0.001). Perceived effectiveness varied: for sleep, 21.4% of caregivers found melatonin very useful, 32.1% somewhat useful, and 39.3% of little or no use. For nocturnal itch, 14.3% found melatonin very useful, 17.9% somewhat useful, and 50.0% of little or no use.</p><p><strong>Conclusions: </strong>There is a high prevalence of melatonin use among children with AD. Most caregivers are initiating melatonin independently, and dosage varies widely. Given mixed caregiver-reported effectiveness of melatonin and limited long-term safety data, it is imperative that further studies are performed to evaluate melatonin's role in children with AD.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145030287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New-Onset Perianal Eroded Lesion in a Pediatric Patient.","authors":"Matthew J Yan, Jayden Galamgam, Amy Shen, Joshua Mo, Marcia Hogeling","doi":"10.1111/pde.70037","DOIUrl":"https://doi.org/10.1111/pde.70037","url":null,"abstract":"","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}