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No Association of Pediatric Vitiligo With Visual Acuity Deficits.
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2025-02-20 DOI: 10.1111/pde.15806
Kristin A Tissera, Amy Buros-Stein, Camile A Delva, Omkar Mayur, Elena B Hawryluk, John Harris, Anna Cristina Garza-Mayers
{"title":"No Association of Pediatric Vitiligo With Visual Acuity Deficits.","authors":"Kristin A Tissera, Amy Buros-Stein, Camile A Delva, Omkar Mayur, Elena B Hawryluk, John Harris, Anna Cristina Garza-Mayers","doi":"10.1111/pde.15806","DOIUrl":"10.1111/pde.15806","url":null,"abstract":"<p><p>Vitiligo is characterized by the autoimmune destruction of melanocytes, which most visibly affect skin pigmentation, but are also present in the choroid and retinal pigmented epithelium of the eye raising the possibility of underappreciated vision loss in affected populations. To inform whether this vulnerable population should be more rigorously screened and offered early intervention, we performed a multi-center retrospective analysis of optotype recognition of 248 pediatric vitiligo patients compared with 496 age- and sex-matched healthy subjects between 2000 and 2023; we found a significant difference in the risk of visual acuity deficits in patients as compared with healthy controls (p = 0.0476), although this association was lost when controlling for family history and genetic diagnoses associated with visual acuity deficits or vision loss. These results extend prior studies in adult populations and are consistent with current guidelines that do not recommend routine vision screening the pediatric vitiligo population, although further studies are warranted to determine if there are more subtle changes in vision and eye function.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"318-321"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Alopecia Areata Disease Severity in Pediatric Patients.
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 DOI: 10.1111/pde.15830
Dingyuan Iris Sun, Amy S Paller
{"title":"Assessment of Alopecia Areata Disease Severity in Pediatric Patients.","authors":"Dingyuan Iris Sun, Amy S Paller","doi":"10.1111/pde.15830","DOIUrl":"10.1111/pde.15830","url":null,"abstract":"<p><p>Alopecia areata (AA) is an autoimmune disorder that causes nonscarring hair loss and significantly impacts quality of life, particularly in pediatric patients. Since the early 2000s, AA severity has been evaluated using the Severity of Alopecia Tool (SALT), which quantifies scalp hair loss. However, recent advancements in the assessment tools provide a more comprehensive evaluation of AA, which is important for both measuring improvement during clinical trials and for a more holistic assessment in routine care. This review examines the development and implementation of assessment tools for AA, including newer tools that incorporate findings beyond the scalp, psychosocial impact, and chronicity. Through these tools, clinicians can gain a more detailed understanding of the multifaceted impact of AA, leading to improved individualized treatment strategies and advancing research in pediatric dermatology.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":"42 Suppl 1 ","pages":"31-35"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882486/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiology of Pediatric Alopecia Areata.
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 DOI: 10.1111/pde.15803
Rutha Adhanom, Brandon Ansbro, Leslie Castelo-Soccio
{"title":"Epidemiology of Pediatric Alopecia Areata.","authors":"Rutha Adhanom, Brandon Ansbro, Leslie Castelo-Soccio","doi":"10.1111/pde.15803","DOIUrl":"10.1111/pde.15803","url":null,"abstract":"<p><p>This contemporary scoping narrative review examines the epidemiology of pediatric alopecia areata (AA), focusing on incidence, prevalence, racial and ethnic differences, and comorbidities. Articles containing original epidemiology on pediatric AA published between 2013 and 2024 were identified. From these studies, the estimated US child and adolescent incidence of AA is between 13.6 and 33.5 per 100,000 person-years, and the prevalence of AA is between 0.04% and 0.11%. Incidence and prevalence rates vary widely by geographic region and nation. A general pattern of highest estimated lifetime prevalence in North African and Middle Eastern nations, followed by high-income North American countries, then by Asian and Western European nations, and, lastly, by Latin America and sub-Saharan Africa emerged. Though infrequently reported, racial and ethnic differences were noted in the largest pediatric-specific studies: Hispanic/Latino, Black, and Asian children were affected by AA at higher rates compared to those who self-identify as White/Caucasian. AA carried a high burden of comorbidities, including atopic disease, vitiligo, mental illness, and thyroid conditions. The existing pediatric epidemiology can help identify potential disparities in care and guide additional research, advocacy, and policy.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":"42 Suppl 1 ","pages":"12-23"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882485/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Agminated Eruptive Melanocytic Nevi and Nail Changes Following Toxic Epidermal Necrolysis in a Pediatric Patient: A Case Report and Systematic Review of the Literature. 一名儿科患者中毒性表皮坏死溶解后的播散性爆发性黑素细胞痣和指甲变化：病例报告和文献系统性综述。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-10-10 DOI: 10.1111/pde.15777
Scott C Jaros, Dean S Morrell, Elizabeth L Nieman
{"title":"Agminated Eruptive Melanocytic Nevi and Nail Changes Following Toxic Epidermal Necrolysis in a Pediatric Patient: A Case Report and Systematic Review of the Literature.","authors":"Scott C Jaros, Dean S Morrell, Elizabeth L Nieman","doi":"10.1111/pde.15777","DOIUrl":"10.1111/pde.15777","url":null,"abstract":"<p><p>Eruptive melanocytic nevi (EMN) have been reported in the setting of immunosuppression, chemotherapy, and bullous skin disease, including less commonly, Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). This case report presents a 4-year-old girl who developed agminated EMN and nail changes after TEN. A systematic review of the literature supports clinically appropriate follow-up of EMN, as there is no reports of malignancy in EMN following SJS/TEN, nor reports of pediatric melanoma arising within EMN of any etiology. Further study of the possible correlation of nail changes with the development of EMN and better characterization of the dermoscopic features of EMN could improve monitoring and care of these patients.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"364-370"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142472018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperkeratosis in Skin Dimples in Children With Down Syndrome. 唐氏综合征患儿皮肤丘疹角化过度。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-11-06 DOI: 10.1111/pde.15813
Susana Giraldi, Betina Werner, Mariana Aparecida Pasa Morgan, Antonio Torrelo
{"title":"Hyperkeratosis in Skin Dimples in Children With Down Syndrome.","authors":"Susana Giraldi, Betina Werner, Mariana Aparecida Pasa Morgan, Antonio Torrelo","doi":"10.1111/pde.15813","DOIUrl":"10.1111/pde.15813","url":null,"abstract":"<p><p>Down syndrome (DS) is a common chromosomal disorder with distinct phenotypes and skin markers. This study reports 39 DS patients, aged 1-44  months, who presented from birth with rough, brownish skin in the dimples of their knees and/or elbows. Dermoscopy revealed hyperkeratosis with brownish scales, and biopsies in six cases showed papillomatosis and mild hyperkeratosis. In the cases followed, the condition resolved spontaneously. Hyperkeratosis in the skin dimples on the knees and elbows seems to be a congenital and perhaps characteristic finding in patients with DS.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"322-325"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kaposiform Hemangioendothelioma With Features of Congenital Hemangioma Treated With Sirolimus. 使用西罗莫司治疗具有先天性血管瘤特征的脐状血管内皮瘤
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-11-11 DOI: 10.1111/pde.15782
Danny Lee, Jennifer Sui, Alreem Al-Nabti, Deborah Schiff, Catalina Matiz, John Naheedy, Dawn Z Eichenfield
{"title":"Kaposiform Hemangioendothelioma With Features of Congenital Hemangioma Treated With Sirolimus.","authors":"Danny Lee, Jennifer Sui, Alreem Al-Nabti, Deborah Schiff, Catalina Matiz, John Naheedy, Dawn Z Eichenfield","doi":"10.1111/pde.15782","DOIUrl":"10.1111/pde.15782","url":null,"abstract":"<p><p>Kaposiform hemangioendothelioma (KHE) is a vascular neoplasm characterized by abnormal angiogenesis and lymphangiogenesis. Here, we present a case of a 19-month-old male with KHE of the right leg with bony involvement who was initially misdiagnosed with infantile hemangioma. Due to its heterogeneous presentation and frequent occurrence of comorbidities such as Kasabach-Merritt phenomenon, clinical and pathological correlation is essential for diagnosis of KHE.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"415-416"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142625571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alopecic and eroded scalp plaque in a newborn. 新生儿头皮脱发和糜烂。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-10-27 DOI: 10.1111/pde.15742
Rafael Escudero-Tornero, Marta Feito-Rodríguez, Tristán-Gabriel Sobral-Costas, José Manuel Busto-Leis, Raúl De Lucas-Laguna
{"title":"Alopecic and eroded scalp plaque in a newborn.","authors":"Rafael Escudero-Tornero, Marta Feito-Rodríguez, Tristán-Gabriel Sobral-Costas, José Manuel Busto-Leis, Raúl De Lucas-Laguna","doi":"10.1111/pde.15742","DOIUrl":"10.1111/pde.15742","url":null,"abstract":"","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"393-395"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142505509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Topical Timolol for Treatment of Spider Angiomas in Children: A Case Series. 外用噻吗洛尔治疗儿童蛛状血管瘤：病例系列。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-10-22 DOI: 10.1111/pde.15788
Marie-Chantal Caussade, Griffin Stockton Hogrogian, Albert C Yan
{"title":"Topical Timolol for Treatment of Spider Angiomas in Children: A Case Series.","authors":"Marie-Chantal Caussade, Griffin Stockton Hogrogian, Albert C Yan","doi":"10.1111/pde.15788","DOIUrl":"10.1111/pde.15788","url":null,"abstract":"<p><p>We report five cases of spider angiomas in children treated topically with timolol 0.5% (ophthalmic solution or gel-forming solution), for 6 months. Parents and patients were advised to apply one drop twice daily. Four of them showed either partial (2) or complete response (2) and only one patient had no clinical change. No adverse effects were reported. This pilot case series shows that topical timolol may prove useful as a noninvasive, available and well-tolerated treatment option for spider angiomas in children who seek a treatment alternative to pulsed dye laser.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"339-341"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142505511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neonatal Miliaria Pustulosa-A Case Series. 新生儿脓疱疮--病例系列。
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-11-10 DOI: 10.1111/pde.15817
Gabrielle Keller Goff, Sarah L Stein, Adena E Rosenblatt
{"title":"Neonatal Miliaria Pustulosa-A Case Series.","authors":"Gabrielle Keller Goff, Sarah L Stein, Adena E Rosenblatt","doi":"10.1111/pde.15817","DOIUrl":"10.1111/pde.15817","url":null,"abstract":"<p><strong>Background/objectives: </strong>Miliaria pustulosa is a noninfectious, transient skin eruption of pustules overlying erythematous plaques secondary to obstruction of eccrine glands. There are very few case reports in the literature detailing miliaria pustulosa in neonates. When presenting in neonates, its similarity to life-threatening infections may cause diagnostic confusion. By differentiating this condition from similar presentations, unnecessary treatments and tests in this population may be avoided.</p><p><strong>Methods: </strong>Retrospective review of the medical records of nine neonates presenting with a pustular eruption diagnosed as miliaria pustulosa. Patients were seen at a children's hospital in Chicago, IL, USA; cases were selected by investigator recall.</p><p><strong>Results: </strong>In this case series, miliaria pustulosa presents in nine neonates as clusters of eruptive pustules with resolution or significant improvement noted after an average of 2.6 days (range 1-5 days). The average age was 4.6 days (range 1-10 days old) and the average gestational age was 34.7 weeks (range 26.3-40.1 weeks). All patients had pustular outbreaks in areas occluded by swaddling, clothes, or adhesive. Seven patients had geometric lesions that were underlying sites of intravenous (IV) site adhesive or electrocardiogram (EKG) leads.</p><p><strong>Conclusions: </strong>The consistent morphological features of this pustular eruption at sites of skin occlusion and the transient course in the setting of an otherwise well-appearing infant are strongly suggestive of the diagnosis of miliaria pustulosa. It is important for clinicians to be familiar with this benign presentation and to differentiate it from other neonatal pustular eruptions to minimize invasive tests and treatments in this vulnerable population.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"278-283"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950795/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142625641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cosmeceuticals in the Pediatric Population Part I: A Review of Risks and Available Evidence.
IF 1.2 4区 医学
Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2025-02-09 DOI: 10.1111/pde.15866
Gabrielle Keller Goff, Sarah L Stein
{"title":"Cosmeceuticals in the Pediatric Population Part I: A Review of Risks and Available Evidence.","authors":"Gabrielle Keller Goff, Sarah L Stein","doi":"10.1111/pde.15866","DOIUrl":"10.1111/pde.15866","url":null,"abstract":"<p><p>The rise in the use of cosmeceuticals among children and adolescents has created a new challenge for dermatologists, who are confronted with the task of advising young patients on the risks that these products can carry and the often questionable efficacy of these products. While some cosmeceuticals can be beneficial for this population when used correctly, such as broad-spectrum sunscreen or specific anti-acne agents, other products may not carry benefits for young skin and could even cause complications, particularly in young consumers who have skin conditions such as acne or atopic dermatitis. Many of the common ingredients in cosmeceutical products have had very limited (if any) studies conducted in pediatric populations, and much of the data regarding the efficacy claims and risks of these products must be inferred from studies in adult patients.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"221-227"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950811/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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