Pediatric DermatologyPub Date : 2025-07-01Epub Date: 2025-04-13DOI: 10.1111/pde.15893
Ferial Alloush, Kei Shing Oh, Hisham F Bahmad, Robert Poppiti, Felipe Pedroso, Carole Brathwaite
{"title":"Soft Pillows, Hard Consequences: A Case Report Unveiling a Down Feather Neck Granuloma in a Pediatric Patient.","authors":"Ferial Alloush, Kei Shing Oh, Hisham F Bahmad, Robert Poppiti, Felipe Pedroso, Carole Brathwaite","doi":"10.1111/pde.15893","DOIUrl":"10.1111/pde.15893","url":null,"abstract":"<p><p>Down pillows, fitted with soft feathers, are commonly used among parents for their children due to their comfort, breathability, and warmth. In this case report, we present a 17-month-old boy who presented with a chief complaint of fever and progressive left neck swelling warranting a surgical excision after a failed course of antibiotic therapy. Histopathologic examination of the lesion demonstrated down feathers with associated granuloma with foreign-body type giant cell reaction, attributed to the use of the down pillow.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"894-895"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pediatric DermatologyPub Date : 2025-07-01Epub Date: 2025-05-14DOI: 10.1111/pde.15985
Roderic Phillips, Catherine Crock
{"title":"Value of Whole Skin Examination in Older Children Presenting With Skin Conditions.","authors":"Roderic Phillips, Catherine Crock","doi":"10.1111/pde.15985","DOIUrl":"10.1111/pde.15985","url":null,"abstract":"<p><strong>Background: </strong>Medical teaching has always emphasized the importance of a good history and a complete medical examination. Missing some areas of examination can lead to errors in diagnosis and management and to adverse outcomes. At the same time, factors including time pressures, medicolegal concerns, and the desire to avoid embarrassment for patients have led to many practitioners routinely bypassing genital and/or breast examination.</p><p><strong>Methods: </strong>This study is a prospective audit of examination findings in patients attending their first appointment at a consultant pediatric dermatology clinic.</p><p><strong>Results: </strong>Data were collected on 221 adolescents, and 46 (20%) of them had unexpected findings on skin during genital and/or breast examination. These findings were not mentioned in history and were sufficient to change the management plan in some way. In 24 cases (10%), the change in plan involved a changed prescription and/or identification of a new problem requiring ongoing management. These findings included eczema, psoriasis, new moles, molluscum, vitiligo, severe phimosis, hidradenitis, and acanthosis nigricans.</p><p><strong>Conclusion: </strong>During history taking, anogenital pathology is often not revealed by the adolescent or the family. Inspection of the anogenital area may be of value in optimizing the medical management plan for an adolescent. Reasons for examination should be explained and the exam performed respectfully with discretion.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"779-781"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pediatric DermatologyPub Date : 2025-07-01Epub Date: 2025-05-29DOI: 10.1111/pde.15978
Clint Christian T Garbanzos, Jorge A Rios-Duarte, Heather D Hardway, Austin Todd, Dawn M R Davis, Julia S Lehman
{"title":"Direct Immunofluorescence (DIF) Microscopy of Skin Biopsies From Children: A Retrospective Cohort Study of 986 DIF Studies.","authors":"Clint Christian T Garbanzos, Jorge A Rios-Duarte, Heather D Hardway, Austin Todd, Dawn M R Davis, Julia S Lehman","doi":"10.1111/pde.15978","DOIUrl":"10.1111/pde.15978","url":null,"abstract":"<p><strong>Background/objectives: </strong>Immune-mediated skin disorders, such as immunobullous dermatoses and leukocytoclastic vasculitis, rarely affect children. While direct immunofluorescence (DIF) biopsy is a standard diagnostic tool, limited data exist on pediatric DIF patterns, rates of positivity, pretest diagnostic concordance, and the relevance of biopsy site. This study sought to address these gaps.</p><p><strong>Methods: </strong>DIF data from all skin and mucosal specimens interpreted at Mayo Clinic's reference immunodermatology laboratory for patients aged 0-18 years (August 22, 2017 to November 30, 2023) were reviewed. DIF results were classified as positive if a characteristic pattern was seen and negative if the findings were negative or nondiagnostic.</p><p><strong>Results: </strong>Of 986 pediatric DIF studies, 153 (15.5%) were positive and comparable to adult positivity rates (20.9%) during the same period. The most frequent DIF patterns were IgA-predominant vasculitis (N = 85/153; 55.5%) and lichenoid tissue reaction (N = 21/153;13.7%). Concordance between pretest diagnosis and positive DIF results was highest for linear IgA bullous dermatosis (N = 7/7; 100%) and dermatitis herpetiformis (N = 6/6; 100%). Excluding these entities, DIF changed the pretest diagnosis in 16.7% (N = 19/114) of cases. While lower extremity biopsies were initially more likely to yield positive DIF results, this association disappeared when IgA vasculitis cases were excluded.</p><p><strong>Conclusion: </strong>The most frequent DIF pattern in children was that of IgA-predominant vasculitis. Pediatric DIF positivity rates closely mirrored those of adults, supporting similar biopsy thresholds. DIF results differed from the pretest impression in a substantial percentage, supporting the value of DIF in select situations in the pediatric population. After controlling for IgA vasculitis, biopsy site was not associated with DIF positivity.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"767-772"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pediatric DermatologyPub Date : 2025-07-01Epub Date: 2025-03-10DOI: 10.1111/pde.15829
Jason Hynes, Niamh Leonard, Maeve Lynch
{"title":"Isolated Hypopigmentation on the Upper Lip of a 12-Year-Old Boy.","authors":"Jason Hynes, Niamh Leonard, Maeve Lynch","doi":"10.1111/pde.15829","DOIUrl":"10.1111/pde.15829","url":null,"abstract":"","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"860-862"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pediatric DermatologyPub Date : 2025-07-01Epub Date: 2025-02-06DOI: 10.1111/pde.15897
Margaret Hurley, Jennifer Scott, Andrea L Zaenglein
{"title":"Management of Hypergranulation Tissue: A Report of a Pediatric Case.","authors":"Margaret Hurley, Jennifer Scott, Andrea L Zaenglein","doi":"10.1111/pde.15897","DOIUrl":"10.1111/pde.15897","url":null,"abstract":"<p><p>Hypergranulation tissue is the overgrowth of granulation tissue during the proliferative phase of wound healing. Treatment of hypergranulation tissue in the pediatric patient is focused on efficacious and comfortable options, of which topical steroids have been successfully used. This report discusses management of a large area of hypergranulation and concurrent infection on the scalp of a pediatric patient.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"896-898"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12285563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pediatric DermatologyPub Date : 2025-07-01Epub Date: 2025-04-28DOI: 10.1111/pde.15916
Shaliz Aflatooni, Nicholas Chin, Amberlyn Colina, Andrew C Krakowski, Lilia Correa-Selm, Thomas Beachkofsky
{"title":"Laser Surgery in Pediatric Skin of Color Patients: A Systematic Review.","authors":"Shaliz Aflatooni, Nicholas Chin, Amberlyn Colina, Andrew C Krakowski, Lilia Correa-Selm, Thomas Beachkofsky","doi":"10.1111/pde.15916","DOIUrl":"10.1111/pde.15916","url":null,"abstract":"<p><p>There are unique challenges in treating dermatologic conditions with lasers in pediatric patients with skin of color. Melanin in the basal epidermis scatters thermal energy, reducing laser effectiveness and increasing the risk of adverse effects. This systematic review summarizes laser treatment of dermatological conditions in pediatric patients with Fitzpatrick skin types (FST) IV-VI, reviewing laser parameters, efficacy, and potential side effects in this vulnerable population. Twenty-three studies using various designs were included after screening, with a total of 164 patients, aged 1 month-17 years. Our systematic review demonstrates that laser surgery in children with FST IV-VI is an excellent option for various dermatological conditions. Children with skin of color should not be excluded from laser surgery, as early treatment can lead to improved clearance and better clinical results. However, laser surgery in this population requires careful consideration regarding laser parameters and desired clinical outcomes. Trial Registration: Prospero ID CRD42024524971.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"700-715"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pediatric DermatologyPub Date : 2025-07-01Epub Date: 2025-05-15DOI: 10.1111/pde.15983
Asfia Numani, Rachel Ziebart, Austin Todd, Afsaneh Alavi, Nessa Aghazadeh Mohandesi, Dawn M R Davis
{"title":"Characterizing Disease Severity, Comorbidities, and Treatment Plans in Pediatric Hidradenitis Suppurativa Patients With and Without Obesity: A Cohort and Cross-Sectional Analysis.","authors":"Asfia Numani, Rachel Ziebart, Austin Todd, Afsaneh Alavi, Nessa Aghazadeh Mohandesi, Dawn M R Davis","doi":"10.1111/pde.15983","DOIUrl":"10.1111/pde.15983","url":null,"abstract":"<p><strong>Background: </strong>Hidradenitis suppurativa (HS) is a chronic inflammatory condition. While obesity is linked to increased HS severity in adults, data on its impact in pediatric HS remain limited. This study investigates the relationships between obesity, HS severity, HS-related comorbidities, and therapeutic management in pediatric patients.</p><p><strong>Methods: </strong>This is a retrospective cohort analysis on patients diagnosed with HS before 18 years of age. Data were collected on disease severity, comorbidity development, and treatments. Trends were compared between HS patients with and without obesity and with healthy controls for comorbidity development.</p><p><strong>Results: </strong>There was no difference in disease severity using Hurley staging between patients with and without obesity (p = 0.679). Patients with obesity were more likely to be prescribed biologics (p = 0.012), but not other treatments. The risk of developing dyslipidemia, anxiety, depression, and thyroid disease was elevated in pediatric HS patients, even after controlling for BMI (p < 0.001).</p><p><strong>Conclusions: </strong>In this study, obesity was not associated with HS disease severity in children. However, children with obesity were more likely to be prescribed biologics. HS may independently increase the risk of dyslipidemia, anxiety, depression, and thyroid disease.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"773-778"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12288943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144078157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psoriasiform Dermatitis Following Kawasaki Disease: A Case Report and Literature Review.","authors":"Shota Nakayama, Naotomo Kambe, Hiroyuki Irie, Kazushi Izawa, Ryohei Nishijima, Hiroo Ueno, Masakazu Fujimoto, Takahiro Yasumi, Kenji Kabashima","doi":"10.1111/pde.15859","DOIUrl":"10.1111/pde.15859","url":null,"abstract":"<p><p>Kawasaki disease (KD) is an idiopathic acute inflammatory illness that commonly affects children in Northeast Asian countries. In this case report, a psoriasiform eruption appeared on the face and extremities following the onset of KD. A review of previous reports identified 38 cases of psoriasiform eruptions following KD, typically appearing 4 days to 2 months after the onset of KD, unlike other skin manifestations associated with the disease. Notably, in this case, the rash improved with the application of white petrolatum, suggesting that psoriasiform eruptions following KD may be self-limited with spontaneous resolution.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"810-816"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142896404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pediatric DermatologyPub Date : 2025-07-01Epub Date: 2025-03-03DOI: 10.1111/pde.15905
Kennedy Sabharwal, Ianna Blanchard, Emily S Gorell, Mariam Iqneibi, Anne W Lucky, David J Worhunsky
{"title":"Junctional Epidermolysis Bullosa With Pyloric Atresia Complicated by Esophageal Atresia and Nephrotic Syndrome: A Case Report and Review of the Literature.","authors":"Kennedy Sabharwal, Ianna Blanchard, Emily S Gorell, Mariam Iqneibi, Anne W Lucky, David J Worhunsky","doi":"10.1111/pde.15905","DOIUrl":"10.1111/pde.15905","url":null,"abstract":"<p><p>Epidermolysis bullosa with associated pyloric atresia (EB-PA) is a rare subtype of epidermolysis bullosa with a high mortality characterized by skin fragility, pyloric atresia, as well as renal and ureteral abnormalities. We present a unique case of EB-PA in a newborn male further complicated by esophageal atresia and nephrotic syndrome. We review the previously reported nine cases of EB-PA with esophageal atresia. However, to our knowledge, this case represents a previously unreported phenotype of EB-PA with esophageal atresia and nephrotic syndrome.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"849-854"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pediatric DermatologyPub Date : 2025-07-01Epub Date: 2025-02-20DOI: 10.1111/pde.15883
Joselyn Ye-Tay, Brian A Moreno, Folasade F Fayiga, Ana M Duarte
{"title":"Rapidly Progressive Rash Associated With Systemic Symptoms in a 5-Year-Old Girl.","authors":"Joselyn Ye-Tay, Brian A Moreno, Folasade F Fayiga, Ana M Duarte","doi":"10.1111/pde.15883","DOIUrl":"10.1111/pde.15883","url":null,"abstract":"","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":"866-868"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}