Antonina Gottman-Narożna, Aleksandra Bala, Weronika Rejner, Agnieszka Olejnik, Kacper Koczyk, Tomasz Dziedzic, Przemysław Kunert
{"title":"Verbal fluency performance in patients with diffuse gliomas located in the supplementary motor area.","authors":"Antonina Gottman-Narożna, Aleksandra Bala, Weronika Rejner, Agnieszka Olejnik, Kacper Koczyk, Tomasz Dziedzic, Przemysław Kunert","doi":"10.1111/jnp.70067","DOIUrl":"https://doi.org/10.1111/jnp.70067","url":null,"abstract":"<p><p>Gliomas frequently arise in the supplementary motor area (SMA), with accumulating evidence indicating that this clinical population may experience cognitive impairment. However, the majority of existing studies have focused primarily on language disturbances associated with SMA damage, while relatively few have examined other cognitive domains, including executive functioning. The present study is the first to include a comprehensive evaluation of verbal fluency performance in patients with gliomas located in the SMA. It included 19 patients with low-grade gliomas (LGGs) 23 with high-grade gliomas (HGGs) and 44 healthy controls. The participants underwent an extensive assessment of verbal fluency encompassing phonemic, semantic, emotional and switching conditions. The findings demonstrated that patients with gliomas in the SMA generated fewer words than healthy volunteers in phonemic (p < 0.001), emotional ('positive', p = 0.009; 'negative', p < 0.001) and switching (p = 0.03) conditions. Patients with HGGs showed worse phonemic fluency performance than patients with LGGs (p < 0.001). There was a lateralisation effect in the switching condition (p = 0.012): patients with tumours in the left hemisphere performed significantly better than those with tumours in the right hemisphere. Epileptic seizures were associated with worse semantic (p < 0.05) and phonemic (p < 0.05) fluency performance. The tumour volume did not have an effect on performance. Lower scores obtained by patients with gliomas located in SMA contribute to understanding the specific cognitive difficulties of this group. This study has validated the importance of expanding assessment of verbal fluency beyond only phonemic and semantic conditions.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148597088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antonio Gil-Ugidos, María López-Corchón, Gavriella Τsiarleston, Víctor Segura-Jiménez, María Teresa Carrillo-de-la-Peña
{"title":"Transcranial electric stimulation in chronic pain: Effects on quality of life, physical function, activity and clinical status.","authors":"Antonio Gil-Ugidos, María López-Corchón, Gavriella Τsiarleston, Víctor Segura-Jiménez, María Teresa Carrillo-de-la-Peña","doi":"10.1111/jnp.70063","DOIUrl":"https://doi.org/10.1111/jnp.70063","url":null,"abstract":"<p><p>Transcranial electric stimulation represents a promising non-invasive neuromodulatory technique targeting maladaptive nociplastic changes in chronic pain (CP) with analgesic effects. However, its impact beyond pain reduction on broader outcomes such as quality of life (QoL) and physical function remains unclear. This study aimed to evaluate the impact of two home-based transcranial electric stimulation modalities, using direct (tDCS) or alternating current (tACS), on improving QoL, addressing comorbid symptoms and enhancing physical function and engagement in physical activity in individuals with CP. In a double-blind randomized controlled trial, 120 CP participants (97 females, 49.5 ± 8.7 years) received 15 sessions of home-based tDCS over the primary motor cortex (M1), tACS over the dorsolateral prefrontal cortex (DLPFC), or sham stimulation. A multidimensional assessment was used before, during and after the treatment, combining subjective measures (QoL, mood, fatigue, sleep quality, perceived physical fitness) and objective metrics (field-based physical fitness tests, accelerometry). Compared with the sham group, both active tES modalities significantly improved QoL, with no differences between M1-tDCS (MD=-7.7; p < .001) and DLPFC-tACS (MD=-7.8; p < .001). However, symptom-specific domains showed no differential effects compared with sham (all p > .05). All groups exhibited increased physical activity during the intervention and improvements in physical function after the intervention (p < .001), suggesting the contribution of contextual factors. Our findings highlight the potential of home-based tES to enhance QoL in CP patients. The lack of differences between intervention groups in domain-specific outcomes (mood, fatigue, sleep) and physical activity underscores the complexity of the therapeutic response, likely influenced by neurophysiological, behavioural, and contextual mechanisms.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148576145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sabrina Bonarota, Giulia Caruso, Carlotta Di Domenico, Francesco Di Lorenzo, Giacomo Koch, Carlo Caltagirone, Marco Bozzali, Laura Serra
{"title":"Are MMSE and ACE-R useful for detecting the earliest stages of Alzheimer's disease? A comparative study.","authors":"Sabrina Bonarota, Giulia Caruso, Carlotta Di Domenico, Francesco Di Lorenzo, Giacomo Koch, Carlo Caltagirone, Marco Bozzali, Laura Serra","doi":"10.1111/jnp.70064","DOIUrl":"https://doi.org/10.1111/jnp.70064","url":null,"abstract":"<p><p>Subjective cognitive decline (SCD) is an at-risk condition for future cognitive decline, making its early identification crucial. We examined whether two widely used screening tools, the Addenbrooke's Cognitive Examination-Revised (ACE-R) and the Mini Mental State Examination (MMSE), can distinguish SCD individuals from healthy elderly (HS) and from individuals with objective cognitive impairment. 110 participants were recruited: 22 HS, 25 SCD, 31 amnestic mild cognitive impairment (aMCI), and 32 Alzheimer's disease (AD) patients. All participants underwent an extensive neuropsychological battery and the ACE-R, which incorporates the MMSE. Partial ACE-R (ACER_P) scores were derived. Between-group comparisons were performed and discriminant analyses were run to evaluate sensitivity, specificity, and accuracy of total ACE-R (ACER_TOT), ACER_P, and MMSE. Despite no screening test significantly distinguishing SCD from HS, a progressive downward trend emerged across groups, with AD performing worst, followed by aMCI, then SCD and HS. Discriminant analyses indicated ACER_TOT had the highest sensitivity for AD (84.4%), with overall accuracy of 59.1%. Sensitivity for HS (68.2%) and aMCI (51.6%) was good but weaker. ACER_P and MMSE yielded similar or lower accuracy. Importantly, all measures poorly detected SCD, with sensitivity below 30%, leading to frequent misclassification as HS or aMCI. Although ACE-R and MMSE are moderately effective for identifying AD, HS and aMCI, they fail to distinguish SCD from other groups. Given the higher risk of SCD of being in AD continuum, such misclassification may prevent appropriate clinical follow-up. More sensitive screening instruments are needed to capture subtle cognitive changes and support early intervention strategies.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148547227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Olivier Cadeau, Jean-Baptiste Muller, Amanda Guerra, Cécile Boscher, Anne Frondas, Jean-Christophe Rozé, Cyril Flamant, Clair-Yves Boquien, Laure Simon, Arnaud Roy
{"title":"Beyond protective factors and normal IQ in preterm children: More executive disorders than expected.","authors":"Olivier Cadeau, Jean-Baptiste Muller, Amanda Guerra, Cécile Boscher, Anne Frondas, Jean-Christophe Rozé, Cyril Flamant, Clair-Yves Boquien, Laure Simon, Arnaud Roy","doi":"10.1111/jnp.70065","DOIUrl":"https://doi.org/10.1111/jnp.70065","url":null,"abstract":"<p><p>Executive functions (EF) are vulnerable in preterm children. Owing to methodological issues, inconsistent findings have left some questions unresolved. This study implemented a theory-guided, integrative EF assessment in preterm children. We also examined the impact of perinatal and sociodemographic features on EF disorder. A quasi-experimental sample of 56 preterm children (28-34 weeks' gestation) aged 7-9 underwent a multidimensional EF assessment, combining performance-based (Child Executive Functions Battery-CEF-B) and daily life measures (Behavior Rating Inventory of Executive Functions-BRIEF, parent and teacher versions). EF disorder were defined as congruent impairments in both the CEF-B Impairment index and the BRIEF Global Executive Composite index (parent or teacher), relative to French norms (scores ≥90th percentile). EF disorder were identified in 30.4% of preterm children, despite an above-average mean intellectual quotient (107 ± 12.5). CEF-B revealed a high prevalence of EF difficulties (19.6% to 51.8% depending on component: inhibition, working memory, flexibility or planning). In everyday life, difficulties are reported overall by parents (23.2%) and teachers (16.4%). CEF-B and BRIEF scores showed low-to-moderate correlations and poor-to-fair congruence. Higher paternal education (OR: 6.73, p = .049) and higher education in both parents (OR: 8.22, p = .033) were protective against EF disorder. Perinatal variables (sex, gestational age, birth weight) and family income showed no significant impact. Findings confirm the high risk of EF difficulties in preterm children. Further work should identify high-risk children for follow-up and support, while raising EF awareness.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148496902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The relationship between psychosocial risk and neurocognitive functioning early after childhood central nervous system tumour diagnosis.","authors":"Jessica Beamish, Riley M Damiano, Josephine Drijver, Femke Aarsen, Martha Grootenhuis, Marita Partanen","doi":"10.1111/jnp.70060","DOIUrl":"https://doi.org/10.1111/jnp.70060","url":null,"abstract":"<p><p>Neurocognitive impairments are common in paediatric central nervous system (CNS) tumours and can relate to clinical and demographic factors. The impact of social or environmental factors, such as family psychosocial risk, is less well understood. We examined neurocognitive functioning in children with CNS tumours shortly after diagnosis and associations with psychosocial risk. This cohort study included children who underwent neuropsychological assessments within three months of diagnosis. Proportion, chi-square and t-tests were used to compare neurocognitive outcomes to norms and evaluate prevalence of neurocognitive impairment (International Cognition and Cancer Task Force criteria: two scores at z ≤ -1.5, one score at z ≤ -2 or both). Regression analyses examined associations between psychosocial risk, age at diagnosis and neurocognitive outcomes, controlling for medical factors. We included 125 children (47 females; mean age at diagnosis = 9.7 years) assessed at an average of 2.08 months after diagnosis. A larger proportion of patients demonstrated neurocognitive impairments than normative expectations (p = .002), with a greater likelihood for children from increased psychosocial risk groups (p = .014). Increased psychosocial risk was associated with lower parent-reported executive functioning (p = .028), but not with other neurocognitive outcomes. Midline tumour location was related to better working memory; history of obstructive hydrocephalus was related to poorer verbal memory and chemo/radiotherapy initiation was related to poorer processing speed (p's < .05). A sub-group of children with CNS tumours show neurocognitive impairments shortly after diagnosis. Children with increased family psychosocial risk were at higher risk of impairment. Psychosocial risk can help identify neurocognitively vulnerable children, highlighting the importance of both neuropsychological and psychosocial screening.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148496804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marnie Drake, Shannon Scratch, Emma Tavender, Rowena Conroy, Taylor Jenkin, Adam Scheinberg, Katherine Lingard-Smith, Kate Heine, Sarah Knight
{"title":"Co-producing process maps to understand and support improvements in the hospital-to-school transition following moderate-to-severe acquired brain injury in primary school-aged children.","authors":"Marnie Drake, Shannon Scratch, Emma Tavender, Rowena Conroy, Taylor Jenkin, Adam Scheinberg, Katherine Lingard-Smith, Kate Heine, Sarah Knight","doi":"10.1111/jnp.70059","DOIUrl":"https://doi.org/10.1111/jnp.70059","url":null,"abstract":"<p><p>Hospital-to-school transition following moderate-to-severe acquired brain injury (ABI) is a complex, cross-sectoral process, requiring timely and coordinated information sharing between health professionals, parents and educators. Despite its importance, families and educators often feel underprepared to support the child's return to school following ABI. This study aimed to develop and describe a participatory process mapping (PM) methodology to visualise and understand information sharing processes during hospital-to-school transition for primary school-aged children with ABI. This novel, cross-sector, two-staged PM approach involved co-developing seven child case maps through triangulation of semi-structured interviews with parents, health professionals and educators (n = 23) and medical records reviews (Stage 1). Stage 2 comprised participatory workshops with 16 stakeholders across health, community and educator sectors to synthesise case maps into an overall hospital-to-school transition process map. The final map depicted non-linear, iterative pathways of information transfer across inpatient, outpatient and school settings. Findings revealed variability in communication channels, a lack of standardised protocols and reliance on parents as primary mediators for transferring information between hospital and schools with limited resources available to support them to advocate effectively. Schools received tailored recommendations after the child had returned to school and limited provision of ABI-related resources. PM provided a pragmatic, collaborative research tool to visualise complex, cross-sector processes and identify gaps in information delivery. This method offers a foundation for driving improvements and developing targeted interventions to improve hospital-to-school transitions in paediatric rehabilitation for children with ABI.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148337068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Taylor Jenkin, Adam Scheinberg, Emma Tavender, Carolyn Pinto, Aayushi Khillan, Adam McKay, Natasha Lannin, Vicki Anderson, Sarah Knight
{"title":"'In This Together': Co-designing a novel knowledge translation intervention to support understanding and management of agitation and altered consciousness following paediatric acquired brain injury.","authors":"Taylor Jenkin, Adam Scheinberg, Emma Tavender, Carolyn Pinto, Aayushi Khillan, Adam McKay, Natasha Lannin, Vicki Anderson, Sarah Knight","doi":"10.1111/jnp.70055","DOIUrl":"https://doi.org/10.1111/jnp.70055","url":null,"abstract":"<p><p>Many children experience agitation and altered consciousness during early acquired brain injury (ABI) recovery, requiring multidisciplinary collaboration across the care pathway. However, limited research evidence and variability in management approaches compromise the provision of standardised, best practice care. This study aimed to co-design and pilot a targeted, evidence-informed implementation intervention to improve inpatient care for children with ABI experiencing altered consciousness and agitation. An Advisory Group was established, comprising 10 clinicians and one parent with lived experience of paediatric ABI (pABI). An evidence-informed, experience-based co-design (E2CD) process was followed and involved 'understanding' current evidence, clinical practice and lived experience perspectives using a scoping review, clinician survey, audit and qualitative interviews (Phase 1); 'refining' this understanding in the local context (Phase 2); 'prioritising' evidence-practice gaps (Phase 3); 'co-designing' resources (Phase 4); and 'implementing and evaluating' the resources through pilot testing (Phase 5). The 'In This Together' micro-learning videos were developed, comprising five 'bite-sized' videos that provide trauma-informed information and tips on managing agitation, uncertainty and transitions in care. The videos aim to support a shared understanding of these topics among clinicians and families and seek to provide families with knowledge and strategies to empower them during their child's care. Pilot testing with clinicians in the local setting indicated that the videos are acceptable, appropriate and feasible. This study highlights the value of partnership with key stakeholders throughout the research process and resulted in the development of micro-learning videos that meaningfully address their needs and have a greater chance of clinical implementation and sustainability.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148300400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Claire Maussire, Mohamad El Haj, Etienne Emmelin, Jérémy Besnard
{"title":"Introducing ISPA-AD: Interactive social problem-solving assessment for Alzheimer's disease","authors":"Claire Maussire, Mohamad El Haj, Etienne Emmelin, Jérémy Besnard","doi":"10.1111/jnp.70030","DOIUrl":"10.1111/jnp.70030","url":null,"abstract":"<p>Social adaptation difficulties in Alzheimer's disease (AD) are frequently associated with impairments in social cognition, including theory of mind and emotion recognition. However, social problem-solving (SPS) may also be a crucial yet understudied component of these deficits. This study aimed to develop and conduct an exploratory evaluation of the Interactive Social Problem-Solving Assessment for Alzheimer's Disease (ISPA-AD), an experimental tool addressing the lack of instruments to evaluate SPS in AD. ISPA-AD presents interactive scenarios designed to evaluate verbal and non-verbal components of SPS. Forty-one participants (19 AD patients and 22 healthy controls) completed the task. Psychometric analyses examined internal consistency, construct validity and discriminative ability. ISPA-AD showed good internal consistency (α = .811), strong construct validity and excellent accuracy in distinguishing AD participants from controls (AUC = .906). AD patients exhibited significantly lower SPS performance, revealing a specific pattern of deficits across the task dimensions. ISPA-AD provides a novel, ecologically grounded approach to assessing SPS in AD. These preliminary findings support its clinical relevance and suggest that the tool may offer valuable insights into the social cognitive mechanisms underlying adaptive behaviour in AD. Further validation in larger and more diverse samples, including reliability studies, is warranted.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":"20 2","pages":"361-374"},"PeriodicalIF":1.8,"publicationDate":"2026-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146058248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Catherine Bosyj, Jelena P. King, Christina Gojmerac, Bruno Losier, Heather E. McNeely
{"title":"An open label investigation of the feasibility and effectiveness of Memory Boost: A novel brief group cognitive remediation intervention for adults with mixed mood and anxiety disorders","authors":"Catherine Bosyj, Jelena P. King, Christina Gojmerac, Bruno Losier, Heather E. McNeely","doi":"10.1111/jnp.70038","DOIUrl":"10.1111/jnp.70038","url":null,"abstract":"<p>To evaluate the feasibility and effectiveness of a novel group cognitive remediation (Memory Boost) designed to improve memory in an adult mixed mood and anxiety disorder population. A secondary aim was to explore the relationship between mood symptoms and performance on subjective and objective memory measures. Participants were adults (<i>n</i> = 99) being treated for a primary diagnosis of a mood disorder in an ambulatory mental health and addictions program who completed Memory Boost between 2014 and 2020. Assessments were completed pre- and post-intervention using self-report measures of mood, anxiety and stress, subjective memory difficulties, confidence in memory and use of memory strategies. Selected subtests of the Rivermead Behavioural Memory Test were administered as objective measures of memory. Over 76% of the sample was retained to post-group test completion. There were significant improvements on subjective measures of memory satisfaction, capability, use of strategies and frequency of mistakes; no significant changes in objective memory performance were observed. Significant improvements were noted in self-reported ratings of depression symptoms, with a significant positive correlation noted between changes in subjective memory and mood improvement. Results indicate that participation in Memory Boost was feasible and associated with improved subjective perception of memory and increased use of cognitive compensatory strategies in a mixed diagnosis adult mood and anxiety disorder sample. Improvement in self-reported mood was also noted and positively correlated with changes in subjective memory, suggesting that a brief cognitive remediation intervention may be a feasible and effective adjunct therapy to mood disorders treatment as usual.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":"20 2","pages":"426-444"},"PeriodicalIF":1.8,"publicationDate":"2026-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jnp.70038","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147454886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}