Orthodontics & Craniofacial Research最新文献

{"title":"Paediatric Sleep-Disordered Breathing Special Issue Introductory Editorial.","authors":"Carlos Flores-Mir, Hong He","doi":"10.1111/ocr.70042","DOIUrl":"10.1111/ocr.70042","url":null,"abstract":"","PeriodicalId":19652,"journal":{"name":"Orthodontics & Craniofacial Research","volume":" ","pages":"391-393"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145355491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the Effects of Low-Level Laser Therapy in Different Wavelengths on Inter-Premaxillary Expansion in Rats Using Micro-Computed Tomography and Histological Methods.","authors":"Emin Isgandarov, Ahmet Yagci, Hasibe Baser Keklikci, Arzu Hanim Yay, Demet Bolat, Mustafa Ermis","doi":"10.1111/ocr.70072","DOIUrl":"10.1111/ocr.70072","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to investigate the effects of low-level laser therapies (LLLTs) with four different wavelengths (532, 650, 810 and 940 nm) on new bone regeneration during inter-premaxillary suture expansion in rats.</p><p><strong>Materials and methods: </strong>Sixty rats were divided into five groups (n = 12): control (Group A) and four laser groups (Group B: 940 nm, Group C: 810 nm, Group D: 650 nm and Group E: 532 nm). Each group was further divided into two subgroups (n = 6) based on the sacrifice day: Day 7 and Day 14. The upper incisors of the rats were drilled, and a 30-g force expansion appliance was inserted. The study lasted 14 days, with 7 days of expansion and 7 days of retention. LLLT was administered at 48-h intervals in groups other than the control group. Bone regeneration in the suture was assessed using micro-computed tomography and immunohistochemistry. Trabecular number (Tb.N), trabecular thickness (Tb.Th) and trabecular separation (Tb.Sp) were measured by using micro-computed tomography. Alkaline phosphatase (ALP), bone morphogenetic protein 2 (BMP-2) and tartrate-resistant acid phosphatase (TRAP) immunoreactivity intensities were calculated in the immunohistochemically stained upper jaw sections.</p><p><strong>Results: </strong>In Group B (940 nm), ALP was significantly higher on the 7th day (p < 0.001); ALP and BMP-2 were significantly higher (p = 0.002; p = 0.013, respectively), and Tb.Sp was significantly lower on the 14th day (p = 0.034) compared with the control group.</p><p><strong>Conclusions: </strong>The results show that 940 nm low-level laser therapy accelerates bone regeneration more effectively in the expanded inter-premaxillary suture.</p>","PeriodicalId":19652,"journal":{"name":"Orthodontics & Craniofacial Research","volume":" ","pages":"521-530"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145990249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-Dimensional Volumetric Assessment of Root Resorption in Rapid Maxillary Expansion: A Meta-Analysis Comparing Tooth-Borne and Bone-Borne Devices.","authors":"Chen Xue, Jianrong Wu, Lan Liu, Ya Qiu, Lihua Li","doi":"10.1111/ocr.70096","DOIUrl":"10.1111/ocr.70096","url":null,"abstract":"<p><p>To compare the extent of root resorption, assessed via three-dimensional (3D) volumetric CBCT analysis, between tooth-borne and bone-borne rapid maxillary expansion (RME) devices. A systematic search of seven databases (PubMed, Cochrane Library, Embase, etc.) up to December 2024 identified eligible studies (randomised controlled trials, cohort studies, clinical trials) evaluating CBCT-measured root resorption in patients treated with tooth-borne, bone-borne or hybrid RME devices. Data were analysed using STATA 17.0, employing weighted mean differences (WMDs) and random/fixed-effects models. Heterogeneity, subgroup analyses and publication bias were assessed. Sixteen studies (525 patients, 2906 teeth) were included. These studies comprised randomised controlled trials and observational studies, predominantly enrolled adolescent and young adult patients, and directly compared tooth-borne and bone-borne RME devices. Tooth-borne RME resulted in significantly greater root resorption volume compared to bone-borne devices (WMD = -10.4 mm³, 95% CI [-13.9, -6.9], 95% prediction interval [-11.94, -8.92], p < 0.05; I² = 98.8%). Tooth-borne RME also caused greater root length loss (WMD = -0.14 mm, 95% CI [-0.21, -0.08], 95% prediction interval [-0.20, -0.08], p < 0.05; I² = 95.6%). Tooth-borne RME resulted in significantly greater root resorption volume (WMD = -20.7 mm³) and length (WMD = -0.40 mm) compared to baseline, indicating increased resorption. Three-dimensional CBCT analysis demonstrated superior sensitivity in detecting resorption morphology and localization compared to linear measurements. Bone-borne RME devices, which are associated with reduced root resorption risks, may be related to improved force distribution to bony structures. Three-dimensional volumetric CBCT assessment provides a more accurate quantification than linear measurements. Clinically, bone-borne expanders are recommended for high-risk patients, while tooth-borne users require close CBCT monitoring. Findings should be interpreted considering limitations of the included evidence, including heterogeneity in RME devices and protocols, risk of bias in some non-randomised studies, and imprecision due to limited sample sizes in subgroup analyses and lack of long-term data. Trial Registration: International Prospective Register of Systematic Reviews (PROSPERO) registration number: CRD420251018535.</p>","PeriodicalId":19652,"journal":{"name":"Orthodontics & Craniofacial Research","volume":" ","pages":"506-520"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145990286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Practices and Perception of Paediatric Obstructive Sleep Apnea Among Orthodontists and Paediatric Dentists in Brazil: A Mixed-Methods Study.","authors":"Nathalia Carolina Fernandes Fagundes, Renata Travassos da Rosa Moreira Bastos, Arnaldo Perez, Carlos Flores-Mir, David Normando","doi":"10.1111/ocr.12866","DOIUrl":"10.1111/ocr.12866","url":null,"abstract":"<p><strong>Objectives: </strong>To explore orthodontists' (OTs) and paediatric dentists' (PDs) practices and perceptions regarding the screening and management of paediatric obstructive sleep apnea (OSA).</p><p><strong>Methods: </strong>This explanatory sequential mixed methods design included OTs and PDs with active clinical practice in Brazil and encompassed a quantitative phase followed by a qualitative phase. In the quantitative phase, a survey assessing OSA screening and management practices was administered to OTs and PDs practicing in Brazil. Information-rich OTs and PDs were interviewed in the qualitative phase. Descriptive statistics and the chi-square test were used to analyse the survey data, while inductive content analysis was applied to the interview data. The results from both phases were integrated and reported narratively.</p><p><strong>Results: </strong>Three hundred eighty-one OTs and PDs completed the survey, and ten of them were interviewed. Nearly half of OTs and PDs administered sleep questionnaires and demonstrated some knowledge about paediatric OSA signs and symptoms. PDs and OTs primarily offered rapid maxillary expansion and functional mandibular advancement for managing selected children with OSA, with OTs being more frequently involved in this task than PDs. OTs and PDs identified several barriers and expressed the need for support regarding access to reliable screening tools and interprofessional care.</p><p><strong>Conclusion: </strong>Brazilian OTs and PDs were aware of the main signs and symptoms of paediatric OSA and were somewhat involved in offering oral appliance management options. To further define the role of these professionals, increasing support for dental professionals in OSA management and updating existing clinical guidelines is warranted.</p>","PeriodicalId":19652,"journal":{"name":"Orthodontics & Craniofacial Research","volume":" ","pages":"451-462"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142471719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wearing the mandibular advancement orthosis and dental movements: Contribution of a digital monitoring protocol.","authors":"M Gay, M Ducret, R Richert, G Buiret","doi":"10.1111/ocr.12860","DOIUrl":"10.1111/ocr.12860","url":null,"abstract":"<p><strong>Objectives: </strong>Oral appliance (OA) has been increasingly used for the treatment of obstructive sleep apnoea hypopnea syndrome (OSAHS). OAs work by propelling the mandible, increasing the upper airway calibre and reducing collapsibility. While they have shown efficacy in reducing OSAHS, long-term use can lead to adverse effects, such as dental displacement. The present study focuses on the impact on dental displacements of the NARVAL® computer-aided design and manufacturing OA from the ResMed laboratory.</p><p><strong>Materials and methods: </strong>The study included 39 patients aged 18 or older who were treated for OSAHS using OAs initiated between 2019 and 2021 and had initial digital dental impressions. A new digital print was taken for each patient using the TRIOS 4 Wireless intra-oral scanner from 3SHAPE. Dental displacement was measured using a 3D system's GEOMAGIC design X 3D reverse engineering software. The study analysed different blocks of teeth in both the maxillary and mandibular arches. Statistical analysis was conducted to determine the significance of dental displacements.</p><p><strong>Results: </strong>Patients had been wearing the OA for an average of 2.5 years. The study found dental displacements in both the maxillary and mandibular arches. However, these displacements were not statistically significant. Qualitative analysis revealed palatoversion and vestibuloversion, while quantitative analysis showed minor dental displacements.</p><p><strong>Conclusion: </strong>This study on patients wearing the NARVAL® OA for an average of 2.5 years found dental displacements in both the maxillary and mandibular arches. However, these displacements were not statistically significant. The results suggest that the OA, designed using a complete digital workflow, did not significantly impact dental positions. To confirm the impact, further investigations with larger sample sizes, an exclusively digital protocol and a control group are required.</p>","PeriodicalId":19652,"journal":{"name":"Orthodontics & Craniofacial Research","volume":" ","pages":"443-450"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142292821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facial Patterns and Obstructive Sleep Apnea in Children Seeking for Orthodontic Treatment: Data From 3671 Polysomnographic Recordings.","authors":"Derek Mahony, Niroj Bhattarai, Cascella Simona, Bucci Rosaria, Peter Borbély, Peter Petocz, Audrey Yoon, Krisztina Kárpáti","doi":"10.1111/ocr.70020","DOIUrl":"10.1111/ocr.70020","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the association between vertical and sagittal facial profile characteristics and the diagnosis/severity of Obstructive Sleep Apnea (OSA) based on hospital-based polysomnography (PSG) in children attending their first orthodontic visit.</p><p><strong>Materials and methods: </strong>3671 children aged 7 to 9 years who attended a private practice for a first orthodontic consultation were included. Apnea/Hypopnea Index (AHI) was measured from PSG, while vertical and skeletal facial profile characteristics were assessed according to the Modified Sassouni Analysis on lateral cephalogram. Analysis of Variance (ANOVA) was used to compare sagittal and vertical patterns among patient subgroups divided according to AHI (AHI = 0, AHI 1-3, AHI 4-5, AHI 6-10, AHI ≥ 11).</p><p><strong>Results: </strong>No statistically significant difference was found in the AHI according to gender (p = 0.84) and age (p = 0.61). It was observed that 87.3% of children with AHI ≥ 11 had a long facial pattern, whereas those with low AHI values (AHI = 0 or 1 ≤ AHI ≤ 3) were mostly classified as having a normal vertical pattern (p < 0.001). Furthermore, children with AHI ≥ 11 presented with a Class II facial profile or maxillomandibular retrusion, while children with maxillomandibular protrusion and a Class I profile had lower AHI values (AHI = 0 or 1 ≤ AHI ≤ 3, p < 0.001).</p><p><strong>Conclusions: </strong>Class II profile, maxillomandibular retrusion, and increased anterior lower facial height are highly present in severe OSA children between the ages of 7 to 9 years. Therefore, orthodontists are encouraged to consider the possibility of breathing issues in children presenting with such craniofacial features.</p>","PeriodicalId":19652,"journal":{"name":"Orthodontics & Craniofacial Research","volume":" ","pages":"497-505"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13140031/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145001009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paediatric Obstructive Sleep Apnoea-We Have to Work Together!","authors":"May M C Yaneza","doi":"10.1111/ocr.70053","DOIUrl":"10.1111/ocr.70053","url":null,"abstract":"","PeriodicalId":19652,"journal":{"name":"Orthodontics & Craniofacial Research","volume":" ","pages":"385-390"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145355475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"miRNA-337-3p and Matrix Metalloproteinase-9: Expression Patterns in Oral Squamous Cell Carcinoma and Prognostic Value for Cervical Lymph Node Metastasis.","authors":"Hongyan Xu, Peng Zhang, Ying Yang, Jianhu Li, Jiaqiang Xu, Tao Wang","doi":"10.1111/ocr.70093","DOIUrl":"10.1111/ocr.70093","url":null,"abstract":"<p><strong>Objective: </strong>To explore the expression of matrix metalloproteinase 9 and miRNA-337-3p in oral squamous cell carcinoma tissues and analyse their clinical significance.</p><p><strong>Materials and methods: </strong>Postoperative specimens from 30 oral squamous cell carcinoma (OSCC) patients were collected from June 2022 to January 2023, and real-time fluorescence quantitative reverse transcription PCR was used to detect the expression levels of miR-337-3p in cancer tissues and adjacent normal tissues. The correlation between the expression levels of the two and the clinicopathological parameters of patients was analysed.</p><p><strong>Results: </strong>Compared with adjacent normal tissues, the expression of miRNA-337-3p in OSCC tissues was significantly lower (p < 0.05), and its expression level was clearly related to the lymph node metastasis status of OSCC patients (p < 0.05). The positive rates of MMP-9 in OSCC tissue and adjacent normal tissue were 83.33% and 36.67% respectively. Compared with patients in the N0 stage, the expression level of miRNA-337-3p in OSCC tissues of patients in the N₁ + N₂ stage was significantly reduced (p < 0.05).</p><p><strong>Conclusion: </strong>The expression of MMP-9 and miRNA-337-3p in OSCC tissues is related to cervical lymph node metastasis. miRNA-337-3p plays a tumour suppressor role in OSCC and may inhibit OSCC cell invasion and metastasis.</p>","PeriodicalId":19652,"journal":{"name":"Orthodontics & Craniofacial Research","volume":" ","pages":"553-561"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145864398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of the Severity of Paediatric Obstructive Sleep Apnea Hypopnea Syndrome on Postoperative Polysomnography: A Systematic Review.","authors":"Rui Mi, Weijian Xu, Yafen Zhu, Zhijian Xie","doi":"10.1111/ocr.12920","DOIUrl":"10.1111/ocr.12920","url":null,"abstract":"<p><p>To explore the disparities in postoperative polysomnography (PSG) parameters among children with varying severities of obstructive sleep apnea hypopnea syndrome (OSAHS) following tonsillectomy and/or adenoidectomy. Three databases (PubMed, MEDLINE and Web of Science Core Collection) were systematically queried for English-language articles on 10 June 2024. Studies involving patients under the age of 18 who underwent surgery for OSAHS with preoperative and postoperative assessments were eligible for inclusion in this review. This review adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. In all severity groups, postoperative PSG demonstrated a significant reduction in the obstructive apnea hypopnea index (OAHI), ranging from 84.2% to 94.3%. Additionally, the postoperative apnea hypopnea index (AHI) decreased by 35.4% in the group with an AHI ≥ 1/h and < 5/h, by 56.0%-72.7% in the group with an AHI of ≥ 5/h and < 10/h, and by 64.1%-87.0% in the group with an AHI ≥ 10/h. Children with more severe OSAHS are likely to derive greater surgical benefits within a 2-year timeframe. However, the long-term validity of this conclusion requires further substantiation.</p>","PeriodicalId":19652,"journal":{"name":"Orthodontics & Craniofacial Research","volume":" ","pages":"416-422"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143677074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Nasal Airway Obstruction in an Orthodontic Population Using the NOSE Scale.","authors":"Rebecca Petts, Diana Ponsky, Luciane Macedo de Menezes, Tarek ElShebiny, Kristina Wolf, Juan Martin Palomo","doi":"10.1111/ocr.70004","DOIUrl":"10.1111/ocr.70004","url":null,"abstract":"<p><strong>Introduction: </strong>Nasal Airway Obstruction is a common problem affecting 30% of the general population and significantly impacts the quality of life. The objective of this research was to determine nasal airway obstruction prevalence in a population seeking orthodontic treatment using the Nasal Obstruction Symptom Evaluation (NOSE) scale and to determine if practice modalities play a role.</p><p><strong>Methods: </strong>The sample consisted of 431 patients seeking orthodontic care who completed the NOSE survey at an orthodontic residency program, a corporate practice, and a private practice.</p><p><strong>Results: </strong>Obstruction was not correlated with age, gender, or trauma (p < 0.05). The mean of all scores was 8.4 ± 14.7 (95% confidence interval [CI]: 7.0-9.8), ranging from 0 to 80 on a scale of 100. The prevalence of nasal airway obstruction in the orthodontic population was: mild or above-43.9% (95% CI: 39.1%-48.7%); moderate or above-11.4% (95% CI: 8.6%-14.9%); severe-2.6% (95% CI: 1.3%-4.5%); and extreme-0.2% (95% CI: 0.0%-1.3%). The Kruskal-Wallis test showed no significant difference among patients at the three locations.</p><p><strong>Conclusions: </strong>The Prevalence of Nasal Airway Obstruction (Mild to Extreme) in orthodontic populations was 43.9% (95% CI: 39.1%-48.7%), representing or slightly exceeding that of the general population. There was no significant difference between an orthodontic residency program, a corporate practice, and a private practice, indicating that the results are widely applicable. Orthodontists are encouraged to use the NOSE scale as a risk assessment tool, providing additional healthcare services to patients and potentially improving their quality of life.</p>","PeriodicalId":19652,"journal":{"name":"Orthodontics & Craniofacial Research","volume":" ","pages":"490-496"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}