Effects of Bioactive NanoAg-ACP Microparticles on the Bond Strength of a Commercial Orthodontic Adhesive and Enamel Resistance to Demineralization.

IF 2.4 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Orthodontics & Craniofacial Research Pub Date : 2025-06-09 DOI:10.1111/ocr.12948

Kelton Cronquist, Linfeng Wu, Brian R Morrow, Ayman Al Dayeh, Antheunis Versluis, Liang Hong

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引用次数: 0

Abstract

Objective: This study was to assess the effects of nanoAg-ACP microparticles as additional fillers on the shear bond strength of Phase II Dual Cure orthodontic adhesive and the enamel demineralisation of teeth using such adhesive.

Materials and methods: Experimental adhesive was formulated by incorporating 2.5 wt% nanoAg-ACP microparticles into Phase II Dual Cure immediately before use. Brackets were bonded to extracted human premolars using Phase II Dual Cure for one group and experimental adhesive for the second. Samples in each group were randomly assigned to three sub-groups for different post-bonding treatments. Debonding force was measured after post-bonding treatments and used to calculate shear bond strength. DIAGNOdent was used to assess enamel demineralisation for sub-groups treated with acid gels.

Results: The shear bond strength for Phase II Dual Cure and experimental adhesive was 19.06 ± 2.88 and 13.90 ± 2.22 MPa, respectively, after 24-h aging, 15.98 ± 5.44 and 15.31 ± 4.22 MPa, respectively, after 5-month aging, and 14.72 ± 3.15 and 14.46 ± 4.66 MPa, respectively, after 3-week demineralisation following 5-month aging. After being aged for 5 months and demineralised for 3 weeks, samples bonded using Phase II Dual Cure had a higher DIAGNOdent value of 65.00 ± 14.66 compared to 49.77 ± 20.64 for samples bonded using experimental adhesive (p < 0.05).

Conclusions: NanoAg-ACP microparticles could be added into Phase II Dual Cure as fillers to resist demineralisation without impairing the shear bond strength. The results warrant further investigation of nanoAg-ACP microparticles as fillers for orthodontic adhesives using more clinically relevant in vitro models to confirm their potential clinical application in orthodontic treatments.

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生物活性纳米ag - acp微粒子对商用正畸胶粘剂粘结强度和牙釉质脱矿抗性的影响。

目的：研究纳米ag - acp微颗粒作为辅助填料对ⅱ期双固化正畸胶粘剂剪切结合强度的影响及对牙釉质脱矿的影响。材料和方法：在使用前立即将2.5 wt% nanoAg-ACP微粒加入II期双固化剂中配制实验粘合剂。一组采用二期双固化法，另一组采用实验性粘接剂。每组样品随机分为3个亚组，进行不同的粘接后处理。测定粘接后的脱粘力，并计算剪切粘接强度。使用诊断仪评估酸凝胶治疗亚组的牙釉质脱矿情况。结果：II期双固化与实验胶粘剂在时效24 h后的剪切强度分别为19.06±2.88和13.90±2.22 MPa，时效5个月后的剪切强度分别为15.98±5.44和15.31±4.22 MPa，时效5个月后脱矿3周后的剪切强度分别为14.72±3.15和14.46±4.66 MPa。经过5个月的陈化和3周的脱矿处理后，ⅱ期双固化材料的诊断值为65.00±14.66，高于实验用胶粘剂的诊断值（49.77±20.64）。(p)结论：在ⅱ期双固化材料中加入纳米ag - acp微粒子作为填料，可以在不影响剪切强度的情况下抵抗脱矿。研究结果表明，纳米ag - acp微颗粒作为正畸粘接剂填充剂的研究需要更多临床相关的体外模型，以证实其在正畸治疗中的潜在临床应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Orthodontics & Craniofacial Research 医学-牙科与口腔外科

CiteScore

5.30

自引率

3.20%

发文量

审稿时长

>12 weeks

期刊介绍： Orthodontics & Craniofacial Research - Genes, Growth and Development is published to serve its readers as an international forum for the presentation and critical discussion of issues pertinent to the advancement of the specialty of orthodontics and the evidence-based knowledge of craniofacial growth and development. This forum is based on scientifically supported information, but also includes minority and conflicting opinions. The objective of the journal is to facilitate effective communication between the research community and practicing clinicians. Original papers of high scientific quality that report the findings of clinical trials, clinical epidemiology, and novel therapeutic or diagnostic approaches are appropriate submissions. Similarly, we welcome papers in genetics, developmental biology, syndromology, surgery, speech and hearing, and other biomedical disciplines related to clinical orthodontics and normal and abnormal craniofacial growth and development. In addition to original and basic research, the journal publishes concise reviews, case reports of substantial value, invited essays, letters, and announcements. The journal is published quarterly. The review of submitted papers will be coordinated by the editor and members of the editorial board. It is policy to review manuscripts within 3 to 4 weeks of receipt and to publish within 3 to 6 months of acceptance.