{"title":"有/无腭裂唇裂患者面罩加微板治疗的预后预测。","authors":"Sungmin Cha, Il-Sik Cho, Il-Hyung Yang, Sungmi Jeon, Jee Hyeok Chung, Mihee Hong, Jin-Young Choi, Seung-Hak Baek","doi":"10.1111/ocr.12941","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To investigate the prognosis prediction of facemask with miniplate (FMMP) therapy in patients with cleft lip with/without palate (CL/P).</p><p><strong>Materials and methods: </strong>The subjects were 103 CL/P patients treated with FMMP therapy. Twenty-five cephalometric variables were measured at preadolescence (T0) and young adulthood (T1). At T1, the subjects were allocated into the FMMP-surgery group (1) when three of the following conditions were met: ANB < -3°, Wits appraisal < -5 mm, APDI > 90° and AB-MP < 60° and (2) when patients were undergoing presurgical orthodontic treatment or had already undergone orthognathic surgery. The mean ages of T0 and T1 and the mean FMMP duration were 8.4, 19.5 and 5.2 years in the FMMP-surgery group (27.2%, n = 28) and 8.5, 18.1 and 4.1 years in the FMMP-nonsurgery group (72.8%, n = 75). Binary logistic regression analysis and receiver operating characteristics analysis were performed.</p><p><strong>Results: </strong>Compared to the FMMP-nonsurgery group, the FMMP-surgery group exhibited a more forward mandibular position and a flatter maxillary occlusal plane at T0, a similar amount of change in the position of point-A, greater forward mandibular growth with larger counterclockwise rotation and an increase in posterior vertical dimension, leading to exacerbation of the skeletal Class III pattern during T1-T0. Four T0 cephalometric predictors (A to N-perpendicular, APDI, FMA and ODI) were identified with high prediction values of accuracy (85.4%) and sensitivity (prediction/actual FMMP-nonsurgery, 93.3%) and moderate value of specificity (prediction/actual FMMP-surgery, 64.3%).</p><p><strong>Conclusion: </strong>These four T0 cephalometric variables were identified as predictors for determining the prognosis in FMMP treatment for patients with CL/P.</p>","PeriodicalId":19652,"journal":{"name":"Orthodontics & Craniofacial Research","volume":" ","pages":""},"PeriodicalIF":2.4000,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prognosis Prediction of Facemask With Miniplate Therapy in Patients With Cleft Lip With/Without Palate.\",\"authors\":\"Sungmin Cha, Il-Sik Cho, Il-Hyung Yang, Sungmi Jeon, Jee Hyeok Chung, Mihee Hong, Jin-Young Choi, Seung-Hak Baek\",\"doi\":\"10.1111/ocr.12941\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To investigate the prognosis prediction of facemask with miniplate (FMMP) therapy in patients with cleft lip with/without palate (CL/P).</p><p><strong>Materials and methods: </strong>The subjects were 103 CL/P patients treated with FMMP therapy. Twenty-five cephalometric variables were measured at preadolescence (T0) and young adulthood (T1). At T1, the subjects were allocated into the FMMP-surgery group (1) when three of the following conditions were met: ANB < -3°, Wits appraisal < -5 mm, APDI > 90° and AB-MP < 60° and (2) when patients were undergoing presurgical orthodontic treatment or had already undergone orthognathic surgery. The mean ages of T0 and T1 and the mean FMMP duration were 8.4, 19.5 and 5.2 years in the FMMP-surgery group (27.2%, n = 28) and 8.5, 18.1 and 4.1 years in the FMMP-nonsurgery group (72.8%, n = 75). Binary logistic regression analysis and receiver operating characteristics analysis were performed.</p><p><strong>Results: </strong>Compared to the FMMP-nonsurgery group, the FMMP-surgery group exhibited a more forward mandibular position and a flatter maxillary occlusal plane at T0, a similar amount of change in the position of point-A, greater forward mandibular growth with larger counterclockwise rotation and an increase in posterior vertical dimension, leading to exacerbation of the skeletal Class III pattern during T1-T0. Four T0 cephalometric predictors (A to N-perpendicular, APDI, FMA and ODI) were identified with high prediction values of accuracy (85.4%) and sensitivity (prediction/actual FMMP-nonsurgery, 93.3%) and moderate value of specificity (prediction/actual FMMP-surgery, 64.3%).</p><p><strong>Conclusion: </strong>These four T0 cephalometric variables were identified as predictors for determining the prognosis in FMMP treatment for patients with CL/P.</p>\",\"PeriodicalId\":19652,\"journal\":{\"name\":\"Orthodontics & Craniofacial Research\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2025-05-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Orthodontics & Craniofacial Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/ocr.12941\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Orthodontics & Craniofacial Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/ocr.12941","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Prognosis Prediction of Facemask With Miniplate Therapy in Patients With Cleft Lip With/Without Palate.
Objective: To investigate the prognosis prediction of facemask with miniplate (FMMP) therapy in patients with cleft lip with/without palate (CL/P).
Materials and methods: The subjects were 103 CL/P patients treated with FMMP therapy. Twenty-five cephalometric variables were measured at preadolescence (T0) and young adulthood (T1). At T1, the subjects were allocated into the FMMP-surgery group (1) when three of the following conditions were met: ANB < -3°, Wits appraisal < -5 mm, APDI > 90° and AB-MP < 60° and (2) when patients were undergoing presurgical orthodontic treatment or had already undergone orthognathic surgery. The mean ages of T0 and T1 and the mean FMMP duration were 8.4, 19.5 and 5.2 years in the FMMP-surgery group (27.2%, n = 28) and 8.5, 18.1 and 4.1 years in the FMMP-nonsurgery group (72.8%, n = 75). Binary logistic regression analysis and receiver operating characteristics analysis were performed.
Results: Compared to the FMMP-nonsurgery group, the FMMP-surgery group exhibited a more forward mandibular position and a flatter maxillary occlusal plane at T0, a similar amount of change in the position of point-A, greater forward mandibular growth with larger counterclockwise rotation and an increase in posterior vertical dimension, leading to exacerbation of the skeletal Class III pattern during T1-T0. Four T0 cephalometric predictors (A to N-perpendicular, APDI, FMA and ODI) were identified with high prediction values of accuracy (85.4%) and sensitivity (prediction/actual FMMP-nonsurgery, 93.3%) and moderate value of specificity (prediction/actual FMMP-surgery, 64.3%).
Conclusion: These four T0 cephalometric variables were identified as predictors for determining the prognosis in FMMP treatment for patients with CL/P.
期刊介绍:
Orthodontics & Craniofacial Research - Genes, Growth and Development is published to serve its readers as an international forum for the presentation and critical discussion of issues pertinent to the advancement of the specialty of orthodontics and the evidence-based knowledge of craniofacial growth and development. This forum is based on scientifically supported information, but also includes minority and conflicting opinions.
The objective of the journal is to facilitate effective communication between the research community and practicing clinicians. Original papers of high scientific quality that report the findings of clinical trials, clinical epidemiology, and novel therapeutic or diagnostic approaches are appropriate submissions. Similarly, we welcome papers in genetics, developmental biology, syndromology, surgery, speech and hearing, and other biomedical disciplines related to clinical orthodontics and normal and abnormal craniofacial growth and development. In addition to original and basic research, the journal publishes concise reviews, case reports of substantial value, invited essays, letters, and announcements.
The journal is published quarterly. The review of submitted papers will be coordinated by the editor and members of the editorial board. It is policy to review manuscripts within 3 to 4 weeks of receipt and to publish within 3 to 6 months of acceptance.