Ophthalmic epidemiologyPub Date : 2026-10-01Epub Date: 2026-05-10DOI: 10.1080/09286586.2026.2665377
Kunrong Li, Wen Sun, Liyang Zhang, Guannan Bai, Pei Wang
{"title":"The Multidimensional Impact of Myopia on Quality of Life Among Chinese Children and Adolescents: A Scoping Review.","authors":"Kunrong Li, Wen Sun, Liyang Zhang, Guannan Bai, Pei Wang","doi":"10.1080/09286586.2026.2665377","DOIUrl":"10.1080/09286586.2026.2665377","url":null,"abstract":"<p><strong>Objective: </strong>To synthesise current evidence on how myopia affects the quality of life (QoL) of Chinese children and adolescents, with a focus on multidimensional health outcomes, contextual determinants, and intervention strategies.</p><p><strong>Methods: </strong>A scoping review was conducted in accordance with PRISMA-ScR guidelines. PubMed, Web of Science, Embase, CNKI, and Wanfang Data were searched from inception to 1 January 2025. Eligible studies included myopic Chinese children and adolescents (≤18 years), used validated QoL instruments, and were published in peer-reviewed journals. Two reviewers independently extracted and verified data, and methodological characteristics were summarised narratively.</p><p><strong>Results: </strong>Twenty-one studies involving 157,441 participants across 14 provinces were included. Myopia was consistently associated with reduced QoL across physical, psychological, and social domains, including limitations in vision-dependent activities, visual symptoms, anxiety, and impaired peer and academic functioning. Key determinants included refractive severity, myopia progression, outdoor activity, screen time, socioeconomic status, and parental education. Interventions including orthokeratology and peripheral defocus lenses, as well as increased outdoor time, show potential to improve functional vision and well-being. However, most evidence comes from cross-sectional studies with heterogeneous QoL measures.</p><p><strong>Conclusions: </strong>Myopia, particularly high myopia, is consistently associated with a significant reduction in the multidimensional QoL of Chinese children and adolescents across diverse regions. This impact reflects a complex bio-environmental interaction involving both physiological progression and lifestyle constraints, such as prolonged screen time and reduced outdoor activity. Future myopia management should transition from a purely refractive focus to holistic strategies that incorporate lifestyle interventions, psychological support, and enhanced patient adaptation to advanced optical treatments.</p>","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"599-612"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147869131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ophthalmic epidemiologyPub Date : 2026-10-01Epub Date: 2026-05-25DOI: 10.1080/09286586.2026.2678907
Christina N Bobrek, Swara M Sarvepalli, Beth Bailey, Majda Hadziahmetovic
{"title":"Prognostic Biomarkers of Survival in Ocular Melanoma.","authors":"Christina N Bobrek, Swara M Sarvepalli, Beth Bailey, Majda Hadziahmetovic","doi":"10.1080/09286586.2026.2678907","DOIUrl":"10.1080/09286586.2026.2678907","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the Surveillance, Epidemiology, and End Results Program (SEER) database in a longitudinal study to determine the factors associated with the risk of death in ocular melanoma.</p><p><strong>Methods: </strong>Patients with a primary diagnosis of ocular melanoma from the SEER database between 1975 and 2022 were included. Chi-square analysis and independent samples <i>t</i> test were performed. The Kaplan-Meier estimate was also run to determine survival months' variability by primary site.</p><p><strong>Results: </strong>The 2,917 included patients were categorized as \"died of ocular melanoma\" or \"alive or dead of other causes.\" Age was higher in patients who died from ocular melanoma (60.7 years ±12) compared to those alive or dead of another cause (57.9 years ±13.5; <i>p</i> < 0.001; OR 0.984; 0.977, 0.992; <i>p</i> < 0.001). The primary site of melanoma was also statistically significantly different between groups; conjunctiva (81.7%) and cornea (81.3%) had the highest survival rate, while the lacrimal gland and an overlapping lesion of the eye and adnexa had the highest mortality rates (100% and 73%, respectively; <i>p</i> < 0.001). Survival analysis with Kaplan-Meier estimate showed lacrimal gland and overlapping lesions of eye and adnexa differed in mean months of survival after diagnosis (54 months and 100.8 months, respectively) compared to conjunctiva and ciliary body (264.5 months and 237.5 months, respectively; <i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>Age and primary site were associated with mortality from ocular melanoma. Overlapping lesions of the eye and adnexa, unspecified ocular site, and choroid were associated with the highest mortality risk from this melanoma.</p>","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"577-581"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148016826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ophthalmic epidemiologyPub Date : 2026-10-01Epub Date: 2026-06-30DOI: 10.1080/09286586.2026.2695756
Kevin T Root, Lauren Jeang, Alvaro J Mejía-Vergara
{"title":"Association Between Demyelinating Disease and Dry Eye Syndrome: A Matched Case-Control Study.","authors":"Kevin T Root, Lauren Jeang, Alvaro J Mejía-Vergara","doi":"10.1080/09286586.2026.2695756","DOIUrl":"10.1080/09286586.2026.2695756","url":null,"abstract":"<p><strong>Purpose: </strong>Demyelinating disease has been associated with dry eye syndrome (DES). Current studies are limited by sample size and confounding autoimmune disorders. Neuromyelitis optica spectrum disorder (NMOSD) has not been associated with DES in a large-scale study to date.</p><p><strong>Methods: </strong>This retrospective case-control study utilized data from the NIH's All of Us Research Database. Cases were patients with DES. Controls were identified with exact matching by birth year (±2 years), sex, race, and ethnicity. Patients with certain confounding diseases, including Sjögren's disease, were excluded. Patients with NMOSD and MS were identified, and aquaporin-4 (AQP4) testing was utilized to reclassify patients as NMOSD. Primary analysis was adjusted for exposure to DES-associated medications. A supplementary cross-sectional analysis was completed to evaluate the association in an unmatched cohort.</p><p><strong>Results: </strong>Cases (<i>n</i> = 25,789) and controls (<i>n</i> = 102,954) were successfully matched. After AQP4-based reclassification and exclusions, 1,065 MS patients (338 cases, 727 controls) and 36 NMOSD patients were analyzed for association with DES. MS was significantly associated with DES adjusted OR 1.61 (95% CI 1.41-1.85). Preliminary analysis also demonstrated NMOSD is associated with DES adjusted OR 3.43 (95% CI 1.74-6.77). Supplementary cross-sectional analysis supported these associations.</p><p><strong>Conclusions: </strong>Both MS and NMOSD are significantly associated with DES, however the NMOSD effect size should be cautiously interpreted given the modest sample size. These findings represent the first moderate-scale epidemiological evidence linking NMOSD to DES. Our results support increased clinical awareness for DES in demyelinating disease patients. However, effect size validation is necessary in future, prospective studies.</p>","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"559-564"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148353164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ophthalmic epidemiologyPub Date : 2026-10-01Epub Date: 2026-06-25DOI: 10.1080/09286586.2026.2693522
Andreas Worm Bendtsen, Lea Lykkebirk, Christopher Maximilian Behrens, Anne Mette Skovgaard, Michael Larsen, Steffen Hamann
{"title":"Longitudinal Development of Macular Ganglion Cell Layer Thickness in Children: The Copenhagen Child Cohort 2000 Eye Study.","authors":"Andreas Worm Bendtsen, Lea Lykkebirk, Christopher Maximilian Behrens, Anne Mette Skovgaard, Michael Larsen, Steffen Hamann","doi":"10.1080/09286586.2026.2693522","DOIUrl":"10.1080/09286586.2026.2693522","url":null,"abstract":"<p><strong>Purpose: </strong>To examine changes in macular ganglion cell layer (GCL) thickness over five years in a community-based birth cohort of children without ophthalmic disease.</p><p><strong>Methods: </strong>This prospective study included 660 children without ophthalmic disease from the Copenhagen Child Cohort 2000 Eye Study. Optical coherence tomography (OCT) scans were analyzed for seven macular GCL thickness and volume measurements. Associations with age, sex, axial length, and OCT signal strength were evaluated. Additionally, GCL thickness was measured in eyes with optic disc drusen (ODD; <i>n</i> = 16) and compared with non-ODD eyes.</p><p><strong>Results: </strong>From around age 11 to 16, macular GCL thickness in boys increased by approximately 1.6%, with statistical significance in six of seven predefined measurements. In girls, GCL thickness was stable or slightly decreased (-0.4%), with significance in four of seven measurements. Baseline axial length (AL) differed significantly between sexes (23.47/22.89 mm in boys/girls, <i>p</i> < 0.0001), as did axial growth between visits (ΔAL, 0.19/0.42 mm in boys/girls, <i>p</i> < 0.0001). No consistent associations were found between AL and GCL thickness or longitudinal changes thereof. After adjusting for potential confounders, four of seven GCL measurements increased significantly with age in boys, while no age-related changes were observed in girls. No significant differences were found in baseline GCL thickness or longitudinal change in GCL between eyes with or without ODD.</p><p><strong>Conclusions: </strong>GCL thickness remained relatively stable between ages 11 and 16, with small but statistically significant differences between sexes.</p>","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"582-590"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148331838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ophthalmic epidemiologyPub Date : 2026-10-01Epub Date: 2026-07-02DOI: 10.1080/09286586.2026.2659618
Richul Oh, Seoyoon Choi, Kyu Hyung Park, Sang Jun Park
{"title":"Nationwide Analysis of Eye-Related Emergency Department Visits in South Korea: NEDIS-EYE REPORT 1.","authors":"Richul Oh, Seoyoon Choi, Kyu Hyung Park, Sang Jun Park","doi":"10.1080/09286586.2026.2659618","DOIUrl":"10.1080/09286586.2026.2659618","url":null,"abstract":"<p><strong>Purpose: </strong>To analyze the diagnosis of eye-related emergency department (ED) visits in South Korea and to investigate the national burden of eye-related visits in the ED and their trends over time.</p><p><strong>Methods: </strong>Data were obtained from the National Emergency Department Information System in South Korea between 2014 and 2022. A total of 74,714,270 ED visits were analyzed. Eye-related ED visits were identified using diagnosis codes at the time of discharge from ED. Temporal trends in annual ED visits were analyzed. Eye-related ED visits were categorized into three groups based on the emergent categories (emergent, unlikely-emergent, and indeterminate).</p><p><strong>Results: </strong>During the 9-year study period, eye-related ED visits accounted for 1,356,169 (1.82%) visits. Total ED visits significantly decreased in 2020 due to the COVID-19 pandemic, with a partial recovery by 2022 to 85% of 2019 levels. The number of eye-related ED visits similarly decreased in 2020, but it continued to decline until 2022, with its proportion dropping from 2.08% in 2014 to 1.58% in 2022 (rate: -0.0547%/year, 95% confidence interval: [-0.0723, -0.0371], <i>p</i> < 0.001). The SIR of total ED visits declined by 6.12% from 2014 to 2022. Among the eye-related ED visits, there were emergent (19.7%), unlikely-emergent (13.2%), and indeterminate (67.1%) cases.</p><p><strong>Conclusions: </strong>Eye-related ED visits in South Korea decreased over the 9-year study period and the proportion of emergent cases increased. The steady decline in eye-related ED visits, along with an increase in emergent cases, may have implications for the allocation of ED resources in the field of ophthalmology.</p>","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"531-539"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148369317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ophthalmic epidemiologyPub Date : 2026-10-01Epub Date: 2026-07-05DOI: 10.1080/09286586.2026.2699400
Jae Ryong Song, Seong-Joon Kim, Jae Ho Jung
{"title":"Normative Percentiles and Age-Related Change Points for RNFL and GCIPL Thickness in Healthy Korean Adults Based on Cirrus HD‑OCT.","authors":"Jae Ryong Song, Seong-Joon Kim, Jae Ho Jung","doi":"10.1080/09286586.2026.2699400","DOIUrl":"10.1080/09286586.2026.2699400","url":null,"abstract":"<p><strong>Purpose: </strong>To generate decade-specific normative percentiles for Korean adults and identify age-related change points in retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIPL) thickness using Cirrus HD optical coherence tomography (OCT).</p><p><strong>Methods: </strong>Cross-sectional, population-based study of 8,558 healthy Korean adults from the Korea National Health and Nutrition Examination Survey (KNHANES) 2017-2021. Cirrus HD-OCT imaging used Optic Disc Cube 200 × 200 protocol for RNFL and Macular Cube 512 × 128 protocol for GCIPL measurements. Simple linear regression change-point (SLRCP) analysis identified age-related change points. Decade-specific percentiles (5th, 25th, 50th, 75th, 95th) were calculated.</p><p><strong>Results: </strong>Cohort included 4,654 women (54.4%) and 3,904 men (45.6%) aged 47.4 ± 13.5 years. Mean RNFL thickness was 95.7 ± 9.1 μm, and GCIPL thickness was 82.7 ± 5.8 μm. Linear regression showed significant age-related decline: RNFL at -0.116 μm/year (95% CI, -0.133 to -0.100; <i>p</i> < .001) and GCIPL at -0.044 μm/year (95% CI, -0.055 to -0.034; <i>p</i> < .001). Women showed thicker RNFL (96.6 vs. 94.9 μm; <i>p</i> < .001), while men had thicker GCIPL (83.0 vs. 82.4 μm; <i>p</i> < .001). SLRCP analysis identified change points with accelerated thinning: GCIPL 51 years (slopes: +0.056 to -0.248 μm/year) and RNFL at 52 years (slopes: -0.079 to -0.240 μm/year). Median RNFL declined from 97 μm (20-29 years) to 87 μm (80-89 years) and GCIPL from 82 μm to 76 μm.</p><p><strong>Conclusion: </strong>RNFL and GCIPL demonstrate nonlinear age-related thinning with accelerated decline beginning in the fifth to sixth decades. These decade-specific normative values and change points provide population- and device-specific references which improve diagnostic accuracy.</p>","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"591-598"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148391496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ophthalmic epidemiologyPub Date : 2026-10-01Epub Date: 2026-06-21DOI: 10.1080/09286586.2026.2689748
Haotian Wu, Lihua Sun, Jun Chen, Bo Zhang, Xun Xu, Xiangui He
{"title":"Online Survey on Myopia Progression Among Chinese Adult Undergraduates: A Pilot Study.","authors":"Haotian Wu, Lihua Sun, Jun Chen, Bo Zhang, Xun Xu, Xiangui He","doi":"10.1080/09286586.2026.2689748","DOIUrl":"10.1080/09286586.2026.2689748","url":null,"abstract":"<p><strong>Purpose: </strong>To estimate the prevalence and severity of myopia progression among adult undergraduates during their college years, providing a foundation for larger-scale stratified surveys.</p><p><strong>Methods: </strong>An online survey targeting Chinese adult undergraduates was conducted via WeChat. The original questionnaire collected data on current refractive status, myopia progression information, family history and lifestyle habits. Non-myopic individuals and those with other ocular diseases were excluded.</p><p><strong>Results: </strong>By June 2024, 996 responses were collected, with 922 included after exclusions. Participants were mostly from Hubei (23.9%), Shanghai (18.2%) and Tianjin (15.8%), majoring in Engineering and Architecture (19.0%), Literature (15.7%) and Medicine (15.2%). The average age was 21.9 ± 1.2 years, and the mean spherical power (SPH) was -3.84 ± 1.80D (left eye) and -4.06 ± 1.81D (right eye). Myopia progression was reported by 56.3% of participants, with the fastest progression during the third year (40.3%) and the second year (28.7%). The fastest annual change of SPH was 0-0.25D (49.5%), followed by 0.25-0.50D (28.5%), 0.50-0.75D (11.0%) and over 0.75D (3.5%). The willingness to adopt myopia control measures was substantial, with 66.3% of participants expressing a preference for specially designed frame glasses. Logistic regression indicated that higher baseline SPH, younger age, and greater stress were associated with myopia progression during college years.</p><p><strong>Conclusion: </strong>Myopia progression is common among Chinese adult undergraduates, particularly during their second and third years. Students experiencing myopia progression show a strong willingness to adopt myopia control interventions. Myopia progression during college years is associated with age, baseline spherical power and academic stress.</p>","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"522-530"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148295859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Traditional Eye Medicine in Indigenous and Rural Populations: A Systematic Review of Prevalence, Determinants, and Clinical Outcomes.","authors":"Luksanaporn Krungkraipetch, Kitti Krungkraipetch, Dechathorn Krungkraipetch","doi":"10.1080/09286586.2026.2665379","DOIUrl":"10.1080/09286586.2026.2665379","url":null,"abstract":"<p><strong>Purpose: </strong>Traditional eye medicine (TEM) is widely used in indigenous and rural communities. Understanding its prevalence, determinants, and clinical implications is essential for developing safe, evidence-informed complementary practices.</p><p><strong>Methods: </strong>A systematic review following PRISMA guidelines searched PubMed, Scopus, Web of Science, and Google Scholar through September 30, 2025. Observational studies reporting TEM prevalence, motivations, or clinical outcomes were included. Findings were synthesized narratively due to heterogeneity. PROSPERO: CRD42025110795.</p><p><strong>Results: </strong>From 3813 records, 10 studies from Africa, Asia, and Latin America were included. TEM prevalence ranged from 18% to 79%, with higher use reported in rural populations and among individuals with ocular symptoms. Most remedies were plant-based; some contained irritants or unsterile components. Users were predominantly female, older, low-income, less educated, and rural. Key predictors included rural residence, family history, prolonged symptoms, distance from hospitals, and limited media access. TEM use was consistently associated with delayed presentation, larger corneal ulcers, worse visual outcomes, higher complication rates, and increased surgical interventions. Training traditional healers improved knowledge and referrals. Overall evidence was low to very low, moderate for prospective cohorts.</p><p><strong>Conclusions: </strong>Across the included observational studies, traditional eye medicine use was associated with delayed presentation and poorer clinical outcomes; however, the certainty of evidence was low to very low, and study design limitations and residual confounding may influence these associations.</p>","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"613-623"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ophthalmic epidemiologyPub Date : 2026-10-01Epub Date: 2026-06-29DOI: 10.1080/09286586.2026.2665382
Lloyd R Kopecny, Hannah Kamgarpour, Ian C Francis, Minas T Coroneo
{"title":"Correspondence: Caution May Be Required with mRNA Covid-19 Vaccinations Related to the Corneal Endothelium.","authors":"Lloyd R Kopecny, Hannah Kamgarpour, Ian C Francis, Minas T Coroneo","doi":"10.1080/09286586.2026.2665382","DOIUrl":"10.1080/09286586.2026.2665382","url":null,"abstract":"","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"624-625"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148345999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ophthalmic epidemiologyPub Date : 2026-10-01Epub Date: 2026-05-11DOI: 10.1080/09286586.2026.2669145
Xing-Wu Zhu, Dan-Lin Li, Peng Lu, Lei Liu, Dan-Ning Hu, Carla Lanca, Andrzej Grzybowski, Chen-Wei Pan
{"title":"Global, Regional, and National Burden of Cataracts Attributable to Household Air Pollution from 1990 to 2021, with Projections to 2035.","authors":"Xing-Wu Zhu, Dan-Lin Li, Peng Lu, Lei Liu, Dan-Ning Hu, Carla Lanca, Andrzej Grzybowski, Chen-Wei Pan","doi":"10.1080/09286586.2026.2669145","DOIUrl":"10.1080/09286586.2026.2669145","url":null,"abstract":"<p><strong>Purpose: </strong>Household air pollution (HAP) is a major environmental risk factor affecting nearly 3 billion people worldwide, and is strongly associated with cataract formation. However, the temporal dynamic and future trends of the global cataract burden attributable specific to HAP remain insufficiently understood. Unlike previous studies focusing on the overall cataract burden, this study quantifies the independent contribution of HAP as an intervenable environmental risk factor.</p><p><strong>Methods: </strong>Using data from the Global Burden of Disease database, we assessed global, regional, and national cataract burden attributable to HAP from 1990 to 2021. Joinpoint regression evaluated temporal trends, Age-Period-Cohort modeling elucidated drivers of burden changes, and health inequality was examined. Future burden was projected using ARIMA and ARIMA-LSTM hybrid models.</p><p><strong>Results: </strong>In 2021, global HAP-attributable cataract burden reached 1956.32 thousand years lived with disability (YLDs), with age-standardized YLDs rate (ASYR) of 22.84 per 100,000. From 1990 to 2021, global YLDs increased steadily, with females consistently exhibiting higher burden than males, while ASYR declined. South Asia and East Asia bore the highest burden, with low socio-demographic index (SDI) regions most affected. Forecasts indicate global YLDs will rise to 1987.94 thousand by 2035, although ASYR will continue declining.</p><p><strong>Conclusion: </strong>HAP is strongly associated with cataracts globally. Females and people living in low-SDI regions are disproportionately affected. There is an urgent need to strengthen clean energy promotion, public health education, and targeted prevention programs in high-burden settings to reduce the cataract burden attributed to HAP.</p>","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"512-521"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147869121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}