Ophthalmologica最新文献

The impact of the COVID-19 pandemic on ophthalmology conferences. COVID-19大流行对眼科会议的影响。

IF 2.1 4区医学

Ophthalmologica Pub Date : 2025-05-27 DOI: 10.1159/000546635

Gabriella Schmuter, Natasha Nayak Kolomeyer, Lisa M Nijm, Jeremiah Tao, Prem S Subramanian, Zaina Al-Mohtaseb, Terry Kim, Aleksandra V Rachitskaya, Janice C Law, Andrea A Tooley

{"title":"The impact of the COVID-19 pandemic on ophthalmology conferences.","authors":"Gabriella Schmuter, Natasha Nayak Kolomeyer, Lisa M Nijm, Jeremiah Tao, Prem S Subramanian, Zaina Al-Mohtaseb, Terry Kim, Aleksandra V Rachitskaya, Janice C Law, Andrea A Tooley","doi":"10.1159/000546635","DOIUrl":"https://doi.org/10.1159/000546635","url":null,"abstract":"Background: The COVID-19 pandemic prompted ophthalmology conferences to transition to virtual platforms. The impact of these changes on attendance and research productivity remains underexplored.Purpose: To evaluate the effects of virtual platforms on attendance and research inclusion at ophthalmology conferences during the COVID-19 pandemic.Methods: This cross-sectional study analyzed data from five ophthalmology conference organizations conducted from 2019 to 2021. Conference meetings were categorized as in-person, virtual, or hybrid. Data included total attendance, trainee participation, and research submissions, obtained directly from each respective organization.Results: Conference meetings integrating a virtual component experienced a cumulative 7% increase in total attendance and a 28% rise in trainee participation. Research submissions rose by 31%, while research acceptances showed variability, with increases observed in some conferences during the virtual years. These trends highlight the potential for virtual platforms to enhance accessibility and engagement, particularly for trainees.Conclusion: Virtual platforms had an overall positive impact on ophthalmology conference attendance and research engagement during the COVID-19 pandemic. Continued integration of virtual components is recommended to enhance accessibility and inclusivity.","PeriodicalId":19595,"journal":{"name":"Ophthalmologica","volume":" ","pages":"1-9"},"PeriodicalIF":2.1,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144160743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Indications and outcomes of patients undergoing Immediate Sequential Bilateral Vitreoretinal Surgery (ISBVS): a case series. 立即序贯双侧玻璃体视网膜手术（ISBVS）患者的适应症和结果：一个病例系列。

IF 2.1 4区医学

Ophthalmologica Pub Date : 2025-05-16 DOI: 10.1159/000546410

Alasdair I Simpson, Anthony Gigon, Shane Whitlow, Gerard McGowan, Sree Burgula, Conor M Ramsden, Aman Chandra, Johannes Keller, Andrew Davies, Rumana Hussain, David H Steel, Shohista Saidkasimova

{"title":"Indications and outcomes of patients undergoing Immediate Sequential Bilateral Vitreoretinal Surgery (ISBVS): a case series.","authors":"Alasdair I Simpson, Anthony Gigon, Shane Whitlow, Gerard McGowan, Sree Burgula, Conor M Ramsden, Aman Chandra, Johannes Keller, Andrew Davies, Rumana Hussain, David H Steel, Shohista Saidkasimova","doi":"10.1159/000546410","DOIUrl":"https://doi.org/10.1159/000546410","url":null,"abstract":"Introduction: Bilateral vision threatening vitreoretinal disease requiring urgent surgery such as proliferative diabetic retinopathy, vitreous haemorrhage and retinal detachment are not uncommon presentations. Accepted practice has been to address each eye in separate, staged procedures. However, there are specific circumstances in which operating on both eyes in the same anaesthetic sitting may be preferable. Immediate Sequential Bilateral Vitreoretinal Surgery (ISBVS) has been rarely described in the literature. We present a series of cases and discuss the indications, risks and relative merits of this approach.Methods: Multicentre retrospective case series of patients undergoing ISBVS. We circulated a proforma to surgeons across the United Kingdom to collate a series of cases of this rarely performed approach to collate indications, operative approach and post-operative results.Results: Seventeen patients (34 eyes) underwent ISBVS from 8 centres. Twenty eyes had rhematogenous retinal detachments, 12 eye had diabetic vitreous haemorrhage or tractional detachment and 2 had full thickness macular hole. Principal pathology was the same bilaterally in each case. Indications for bilateral surgery included bilateral disease requiring urgent surgical intervention, high risk general anaesthetic, anticipated difficulty with follow-up, convenience in post operative care and patient preference. Visual acuity improved in 22 eyes and worsened in 2. Post operative complications included four eyes with elevated intraocular pressure, three vitreous haemorrhages, one cystoid macular oedema and one with a macular fold. One required re-operation for non-clearing vitreous haemorrhage.Conclusions: ISBVS is a useful approach which may be underutilised, but further studies are required to validate its safety.","PeriodicalId":19595,"journal":{"name":"Ophthalmologica","volume":" ","pages":"1-13"},"PeriodicalIF":2.1,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144094490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between ectopic inner foveal layer on optical coherence tomography and postoperative quantitative metamorphopsia in patients undergoing epiretinal membrane surgery. 光学相干断层扫描异位内中央凹层与视网膜前膜手术患者术后定量变形的关系。

IF 2.1 4区医学

Ophthalmologica Pub Date : 2025-05-03 DOI: 10.1159/000546248

Micol Alkabes, Andrea Muraca, Lamberto La Franca, Alessandro Rabiolo, Paolo Fogagnolo, Stefano Ranno, Filippo Frerio, Mattia Marchetti, Davide Wild, Valentina Gatti, Stefano De Cillà

{"title":"Association between ectopic inner foveal layer on optical coherence tomography and postoperative quantitative metamorphopsia in patients undergoing epiretinal membrane surgery.","authors":"Micol Alkabes, Andrea Muraca, Lamberto La Franca, Alessandro Rabiolo, Paolo Fogagnolo, Stefano Ranno, Filippo Frerio, Mattia Marchetti, Davide Wild, Valentina Gatti, Stefano De Cillà","doi":"10.1159/000546248","DOIUrl":"https://doi.org/10.1159/000546248","url":null,"abstract":"Purpose: Epiretinal membrane (ERM) is a condition that can lead to visual impairment and meta-morphopsia. This study aimed to examine the correlation between metamorphopsia and foveal mi-crostructure before and after macular surgery in a cohort of patients with advanced ERM.Methods: The severity of metamorphopsia was quantified using M-CHARTS, and foveal micro-structure was evaluated via two optical coherence tomography (OCT) measures: central foveal thickness (CFT) and ectopic inner foveal layer (EIFL). Assessments were performed pre- and post-surgery with an average follow-up of one year. Correlations between morphological and functional parameters pre- and post-surgery were explored by means of regression analysis.Results: 60 eyes of 57 patients diagnosed with advanced ERM and surgically treated were included in the study. Our findings showed a significant correlation between postoperative metamorphopsia and both pre- (R²=0.431) and postoperative (R²=0.300) EIFL thickness. Disparities were observed in metamorphopsia scores between patients with ERM stages 3 and 4, both pre- (0.46 ± 0.31 and 0.84 ± 0.32, respectively, P<0.01) and post-surgery (0.18 ± 0.21 and 0.46 ± 0.28, respectively, P<0.01). Postoperative EIFL thickness was the only variable significantly associated with postoper-ative metamorphopsia scores according to multiple regression analysis.Conclusion: EIFL thickness emerges as a critical determinant of postoperative metamorphopsia severity, underscoring its importance in predicting functional outcomes after ERM surgery. Although surgery improved metamorphopsia across stages, patients with more advanced ERM experienced less favorable outcomes, stressing the importance of a timely surgical intervention.","PeriodicalId":19595,"journal":{"name":"Ophthalmologica","volume":" ","pages":"1-13"},"PeriodicalIF":2.1,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144018080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to "Readability of AI & Ophthalmologist Responses to Patient Surgery Queries: Comment" by Daungsupawong and Wiwanitkit. Daungsupawong和Wiwanitkit对“人工智能的可读性和眼科医生对患者手术问题的回应：评论”的回应。

IF 2.1 4区医学

Ophthalmologica Pub Date : 2025-04-29 DOI: 10.1159/000546049

Sai S Kurapati, Antonio Yaghy, Derek J Barnett, Ingrid U Scott

引用次数: 0

The Seven Sins of Automated Diabetic Retinopathy Screening: Barriers for Clinical Implementation of Artificial Intelligence-Based Devices in National Screening Programs. 糖尿病视网膜病变自动筛查的七罪：基于人工智能的设备在国家筛查计划中临床实施的障碍。

IF 2.1 4区医学

Ophthalmologica Pub Date : 2025-04-23 DOI: 10.1159/000545969

Jakob Grauslund, Andrzej Grzybowski

引用次数: 0

Treatment effects of panretinal photocoagulation or combined anti-vascular endothelial growth factor therapy for proliferative diabetic retinopathy on the risks of diabetic macular edema and vitreous hemorrhage. 全视网膜光凝或联合抗血管内皮生长因子治疗增殖性糖尿病视网膜病变对糖尿病黄斑水肿和玻璃体出血的影响

IF 2.1 4区医学

Ophthalmologica Pub Date : 2025-04-18 DOI: 10.1159/000545941

Hsuan-Chieh Lin, Yong-Chen Huang, Yi-Ting Hsieh, Shu-Hui Chang

{"title":"Treatment effects of panretinal photocoagulation or combined anti-vascular endothelial growth factor therapy for proliferative diabetic retinopathy on the risks of diabetic macular edema and vitreous hemorrhage.","authors":"Hsuan-Chieh Lin, Yong-Chen Huang, Yi-Ting Hsieh, Shu-Hui Chang","doi":"10.1159/000545941","DOIUrl":"https://doi.org/10.1159/000545941","url":null,"abstract":"Introduction: This study evaluated the effect of panretinal photocoagulation (PRP) or combined both anti-VEGF therapy and PRP in proliferative diabetic retinopathy (PDR) on the risk of diabetic macular edema (DME) or vitreous hemorrhage (VH) and compared functional, anatomical outcomes and additional treatments in the two groups.Methods: This retrospective analysis involves patients treated for PDR with either PRP alone or in combination with three consecutive anti-VEGF injections, followed for at least 12 months. Treatment effects and other factors associated with the risk of first DME and VH were assessed.Results: We identified 95 eyes from 69 patients (combined group: 37 eyes from 25 patients; PRP group: 58 eyes from 44 patients). At one year the cumulative incidences of the first DME and VH were 8% and 19% (combined group), and 31% and 19% (PRP group), respectively. Combined treatment reduced the risk of first DME after adjusting for age, HbA1c level, PDR severity, and baseline CRT (csHR: 0.211, 95% CI: 0.064-0.700, p=0.011). Increased DME risks correlated with poor blood sugar control (HbA1c ≥8.4%), thicker baseline CRT in non-high-risk PDR, and baseline CRT <232μm in high-risk PDR. The risk of first VH decreased with age (csHR: 0.966, 95% CI: 0.933-0.999, p=0.045). The combined group exhibited superior best-corrected visual acuity at the third and twelfth months. The combined group were less likely to require additional treatment within one year (adjusted OR: 0.254, 95% CI: 0.088-0.739, p=0.011).Conclusion: Combining anti-VEGF agents with PRP effectively reduced the risk of DME, yielding improved visual outcomes and fewer additional treatments within one year.","PeriodicalId":19595,"journal":{"name":"Ophthalmologica","volume":" ","pages":"1-20"},"PeriodicalIF":2.1,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Readability of AI & Ophthalmologist Responses to Patient Surgery Queries: Comment. 人工智能的可读性与眼科医生对患者手术问题的回答：评论。

IF 2.1 4区医学

Ophthalmologica Pub Date : 2025-04-17 DOI: 10.1159/000545970

Hinpetch Daungsupawong, Viroj Wiwanitkit

引用次数: 0

Impact of Anatomically Defined Retinal Zones on Ultrawide-Field Fluorescein Angiography Nonperfusion Measurements in Diabetic Retinopathy. 解剖定义的视网膜区域对糖尿病视网膜病变超宽场荧光素血管造影非灌注测量的影响。

IF 2.1 4区医学

Ophthalmologica Pub Date : 2025-04-15 DOI: 10.1159/000545754

Mohamed Ashraf, Abdulrahman Rageh, Michael J Gilbert, Paolo S Silva

{"title":"Impact of Anatomically Defined Retinal Zones on Ultrawide-Field Fluorescein Angiography Nonperfusion Measurements in Diabetic Retinopathy.","authors":"Mohamed Ashraf, Abdulrahman Rageh, Michael J Gilbert, Paolo S Silva","doi":"10.1159/000545754","DOIUrl":"10.1159/000545754","url":null,"abstract":"Introduction: The aims of the study were to determine the effect of retinal zone placement on nonperfusion index (NPI) measurements using ultrawide-field fluorescein angiography (FA) in eyes with diabetic retinopathy (DR) and assess its association with disease progression.Methods: The study analyzed retinal periphery zones based on FA findings in 18 eyes without DR to standardize anatomical boundaries. NPI measurements were then conducted on a separate set of 285 eyes with DR. Eyes were grouped by NPI levels, and Cox regression was used to examine the association between nonperfusion in the mid-peripheral and far peripheral retina and progression to proliferative diabetic retinopathy (PDR).Results: The retinal zones defined by FA (FA-defined zones) were similar in size to a standard 15-mm radius circle centered on the optic disk (14.98 ± 1.40 mm). However, when compared to circles centered on the fovea, the fovea-centered circles were displaced temporally by an average of 3.94 mm, leading to a significant overestimation of the anatomic nasal far periphery (79.10 ± 13.60 mm2 vs. 36.91 ± 10.52 mm2, p < 0.001). Among the eyes with at least 1 year of follow-up (N = 121, 42.5%), those with medium and high mid-peripheral NPI had a significantly higher risk of progression to PDR (HR, 3.44; 95% CI, 1.36-8.70; p = 0.009) when using FA-defined zones. No significant association was found when using fovea-centered zones (HR, 1.39; 95% CI, 0.56-3.46; p = 0.476).Conclusion: While the diameter of the retinal measurement zones did not differ significantly, the location of the zone center had a substantial impact on NPI measurements. Using FA-defined zones centered on the optic disk led to lower mid-peripheral and higher far peripheral NPI measurements, providing a more accurate prediction of progression to PDR compared to fovea-centered zone.","PeriodicalId":19595,"journal":{"name":"Ophthalmologica","volume":" ","pages":"1-8"},"PeriodicalIF":2.1,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Real-world Intravitreal Aflibercept 2 mg Treatment of Macular Oedema Secondary to Retinal Vein Occlusion in Italy: 24-month Results from the AURIGA Observational Study. 在意大利，阿非利赛普2mg玻璃体内治疗继发于视网膜静脉阻塞的黄斑水肿：来自AURIGA观察研究的24个月结果。

IF 2.1 4区医学

Ophthalmologica Pub Date : 2025-04-09 DOI: 10.1159/000545534

Maria Oliva Grassi, Andrea Russo, Maria Vadalà, Helmut Allmeier, Tobias Machewitz, Monica Varano

{"title":"Real-world Intravitreal Aflibercept 2 mg Treatment of Macular Oedema Secondary to Retinal Vein Occlusion in Italy: 24-month Results from the AURIGA Observational Study.","authors":"Maria Oliva Grassi, Andrea Russo, Maria Vadalà, Helmut Allmeier, Tobias Machewitz, Monica Varano","doi":"10.1159/000545534","DOIUrl":"https://doi.org/10.1159/000545534","url":null,"abstract":"Introduction: This subgroup analysis of the global AURIGA study evaluated intravitreal aflibercept 2 mg (IVT-AFL) effectiveness and treatment patterns in routine practice in Italy in patients with macular oedema secondary to branch or central retinal vein occlusion (BRVO/CRVO).Methods: AURIGA (NCT03161912) was a 24-month, prospective observational study in patients for whom IVT-AFL treatment had already been prescribed by their physician. All clinical decisions were according to physician discretion and local practice. Statistical analyses were descriptive only.Results: In Italy, 152 treatment-naïve and 50 pretreated patients participated across 27 centres. Mean (95% confidence interval) change in visual acuity (VA) from baseline to Month (M)12 in treatment-naïve patients was +10.3 (7.0, 13.6) and +12.2 (5.6, 18.8) letters for BRVO and CRVO (baseline: 55.3±20.3 and 44.5±25.5 letters), and pretreated patients gained +6.6 (0.3, 13.0) and +14.6 (5.5, 23.8) letters for BRVO and CRVO (baseline: 56.0±15.9 and 42.4±23.5 letters). In treatment-naïve patients, VA gains by M12 after a mean of 4.8 injections were maintained through M24 after a mean of 5.7 injections from baseline; in pretreated patients, M12 gains were not maintained, despite a similar mean of 5.8 injections by M24. Most injections were received within the first 6 months, with a marked reduction in injection frequency thereafter.Conclusion: Robust VA improvements were observed in treatment-naïve patients with RVO in Italy following IVT-AFL treatment for up to 24 months in routine practice, despite a low injection frequency. However, guidelines indicate that regular, proactive treatment beyond the acute stage is required to improve long-term outcomes.","PeriodicalId":19595,"journal":{"name":"Ophthalmologica","volume":" ","pages":"1-25"},"PeriodicalIF":2.1,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Geographic Atrophy and Peripheral Atrophy: Quantitative Analysis with Ultra-Widefield Autofluorescence. 地理萎缩和外周萎缩：超宽视场自体荧光定量分析。

IF 2.1 4区医学

Ophthalmologica Pub Date : 2025-04-08 DOI: 10.1159/000544958

Daniele De Geronimo, Mariacristina Parravano, Riccardo Sacconi, Eliana Costanzo, Monica Varano, Giuseppe Querques

{"title":"Geographic Atrophy and Peripheral Atrophy: Quantitative Analysis with Ultra-Widefield Autofluorescence.","authors":"Daniele De Geronimo, Mariacristina Parravano, Riccardo Sacconi, Eliana Costanzo, Monica Varano, Giuseppe Querques","doi":"10.1159/000544958","DOIUrl":"10.1159/000544958","url":null,"abstract":"Introduction: To analyze and correlate the topographic distribution of atrophic areas at the posterior pole and peripheral retina in subjects with geographic atrophy (GA) using ultra-widefield fundus autofluorescence (FAF) imaging.Methods: This multicenter observational study included 15 patients (9 males, 19 eyes) with coexisting GA and peripheral atrophy. All eyes were imaged with Ultra-widefield Optos California (Optos, PLC, Dunfermline, Scotland) to acquire ultra-widefield (200°) color and FAF images centered on the fovea, superior, inferior, nasal, and temporal sectors. The extent of GA in the central FAF image and the peripheral atrophic areas in the peripheral FAF images were measured by manually defining the boundaries of the atrophic regions using the \"ROI free\" function integrated into the device software. The values obtained were then analyzed and correlated.Results: The mean ± standard deviation (SD) GA size was 13.9 ± 15.0 mm2 (range: 1.8-71.3 mm2) and the total peripheral atrophy was 51.0 ± 68.3 mm2 (range: 1.4-292.1 mm2). The topographic analysis showed that the mean ± SD of superior peripheral atrophy was 9.0 ± 20.6 mm2, temporal atrophy was 30.5 ± 55.9 mm2, inferior atrophy was 9.3 ± 16.3 mm2, and nasal atrophy was 1.8 ± 3.9 mm2. GA size was significantly correlated with total peripheral atrophy (Rho = 0.463, p = 0.046) and temporal peripheral atrophy (Rho = 0.474, p = 0.040), whereas no correlations were found with peripheral atrophy in the remaining sectors.Conclusion: Ultra-widefield autofluorescence is a valuable technique for visualizing and assessing the extent of macular and peripheral atrophy. Macular atrophy correlates significantly with total and temporal peripheral atrophy but demonstrates no significant correlation with atrophy in the remaining sectors.","PeriodicalId":19595,"journal":{"name":"Ophthalmologica","volume":" ","pages":"1-7"},"PeriodicalIF":2.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143811865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0