Occupational and Environmental Medicine最新文献

{"title":"Sleep disturbances and sleep duration as predictors of working life expectancy among adults aged 50 years and older in Finland.","authors":"Saana Myllyntausta, Katriina Heikkilä, Jaana Pentti, Holendro Singh Chungkham, Sakari Suominen, Mika Kivimaki, Jussi Vahtera, Paola Zaninotto, Jenni Ervasti, Sari Stenholm","doi":"10.1136/oemed-2025-110766","DOIUrl":"https://doi.org/10.1136/oemed-2025-110766","url":null,"abstract":"<p><strong>Objectives: </strong>To examine the associations of sleep disturbances and sleep duration with working life expectancy (WLE; the estimated number of years an individual is expected to be in the workforce) from age 50 to 68.</p><p><strong>Methods: </strong>Data of individuals ≥50 years were drawn from two cohort studies: the Finnish Public Sector (FPS) study involving public sector employees in 2000-2016 (n=70 339, 80% women) and the Health and Social Support (HeSSup) study in 1998-2013 initially representing the general working age population in Finland (n=6071, 54% women). Participants reported sleep disturbances (none, moderate, severe, only in FPS) and usual sleep duration (short: <7 hours, mid-range: 7-8.5 hours, long: ≥9 hours). WLE from age 50 to 68 was estimated using multistate life table models.</p><p><strong>Results: </strong>Reporting no sleep disturbances predicted a WLE of 13.4 years (95% CI 13.4 to 13.5), moderate sleep disturbances a WLE of 13.0 years (95% CI 13.0 to 13.1) and severe sleep disturbances a WLE of 12.8 years (95% CI 12.7 to 12.8) at 50 years of age. Short sleep duration predicted a WLE of 13.2 years (95% CI 13.1 to 13.2), mid-range sleep duration a WLE of 13.2 years (95% CI 13.1 to 13.2) and long sleep duration a WLE of 12.4 years (95% CI 12.3 to 12.6). The findings on sleep duration were more pronounced in HeSSup.</p><p><strong>Conclusions: </strong>Severe sleep disturbances and long sleep duration were associated with a reduction of approximately 8-9 months in WLE compared with no disturbances or mid-range sleep duration. To promote older adults' participation in working life, supporting sleep of recommended length and good quality may be required.</p>","PeriodicalId":19459,"journal":{"name":"Occupational and Environmental Medicine","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148796014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased risk of occupational falls among cancer survivors: Japanese nationwide cohort.","authors":"Kazuhiko Watanabe, Ichiro Kawachi, Takahiro Tabuchi, Masayoshi Zaitsu","doi":"10.1136/oemed-2026-111106","DOIUrl":"https://doi.org/10.1136/oemed-2026-111106","url":null,"abstract":"<p><strong>Objectives: </strong>Despite declining incidence rates for some cancers, the ageing workforce and improved survival have increased the number of workers with a history of cancer. Cancer treatment can affect strength, balance and bone health, thereby increasing fall risk among cancer survivors. However, an association between a history of cancer and occupational falls has not been reported. We aimed to investigate whether a history of cancer was associated with occupational falls and fall-related fractures among workers in Japan using prospective data.</p><p><strong>Methods: </strong>We analysed two-wave panel data from the Japan COVID-19 and Society Internet Survey, a nationwide web-based survey with 1-year follow-up. Cancer history, including active treatment or remission, was assessed at baseline, and occupational falls and fall-related fractures were assessed at the 12- month follow-up. Poisson regression was used to estimate relative risks (RRs) and 95% CIs, adjusting for baseline covariates.</p><p><strong>Results: </strong>Among 11 733 participants (mean age: 42.6 years), 8.0% reported at least one occupational fall in the past 12 months, and 3.7% reported a fall-related fracture. Compared with participants without a history of cancer, occupational fall risk was higher among those in remission (RR 1.90; 95% CI 1.50 to 2.41) and those receiving active treatment (RR 2.38; 95% CI 1.79 to 3.18). Similar associations were observed for fall-related fractures.</p><p><strong>Conclusions: </strong>Workers with a history of cancer had a higher risk of occupational falls and fall-related fractures. Occupational injury prevention strategies should address the needs of workers with a history of cancer.</p>","PeriodicalId":19459,"journal":{"name":"Occupational and Environmental Medicine","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148795998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occupational noise exposure and risk of myocardial infarction: results from a prospective Swedish cohort.","authors":"Claudia Lissåker, Mattias Sjöström, Theo Bodin, Maria Albin, Jenny Selander","doi":"10.1136/oemed-2026-110919","DOIUrl":"https://doi.org/10.1136/oemed-2026-110919","url":null,"abstract":"<p><strong>Objectives: </strong>To explore the association between occupational noise exposure the preceding year and myocardial infarction (MI) and cumulatively.</p><p><strong>Methods: </strong>Data came from the Swedish National Cohort on Work and Health, a cohort of all Swedish individuals born between 1930 and 1990. We included individuals with at least one occupational code between 1985 and 2013, which was matched to a job-exposure matrix for occupational noise in five categories (LAeq8h): <70, 70-74, 75-79, 80-84, ≥85 dB(A). First-time MI was ascertained from national patient registers. We used a discrete-time hazards model to account for time-varying covariates and adjusted for individual confounders and other occupational exposures. We estimated the ORs for noise exposure in the year prior and cumulatively. Sensitivity analyses were done stratifying by sex and restricting to low physical workload.</p><p><strong>Results: </strong>Of 6 680 523 individuals, 75 437 were first MI cases. Compared with <70 dB(A), occupational noise was associated with increased odds of MI across all categories, with 1.13 (1.11-1.15) for 70-74, 1.13 (1.10-1.15) for 75-79, 1.13 (1.10-1.16) for 80-84 and 1.08 (1.04-1.12) for ≥85 dB(A). Associations were similar in restricted analyses to low physical workload and for men; among women, odds were increased at 70-74 and ≥85 dB(A). Cumulative exposure of more than 1 year to ≥85 dB(A) was also associated with increased odds of MI.</p><p><strong>Conclusions: </strong>Occupational noise was associated with modestly elevated odds of MI, with consistent associations for exposure to over 85 dB(A) after taking into account other occupational factors.</p>","PeriodicalId":19459,"journal":{"name":"Occupational and Environmental Medicine","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148796033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of employment characteristics and psychosocial work factors with severe menopausal symptoms among working women: a longitudinal study.","authors":"Miho Iida, Ryota Toki, Atsuko Miyake, Minako Matsumoto, Aya Hirata, Shun Edagawa, Naoko Miyagawa, Sei Harada, Toru Takebayashi","doi":"10.1136/oemed-2026-111118","DOIUrl":"https://doi.org/10.1136/oemed-2026-111118","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate whether employment characteristics and psychosocial work factors are associated with the development of severe menopausal symptoms among working women.</p><p><strong>Methods: </strong>We longitudinally analysed 648 working women aged 35-55 years without menopausal symptoms interfering with daily life at baseline (2012-2014). Employment characteristics included employment status, managerial position, shift work and working hours. Psychosocial work factors included workload, job control, job strain and effort-reward imbalance. At follow-up (2018-2020), women in the menopausal transition or postmenopause who reported menopausal symptoms that interfered with daily life during follow-up were classified as having developed severe menopausal symptoms. Associations between baseline work factors and the development of severe menopausal symptoms were examined using modified Poisson regression adjusted for age, follow-up duration, body mass index, smoking, drinking and educational attainment. Symptom domains (vasomotor, psychological and physical) were also evaluated.</p><p><strong>Results: </strong>During 5.3±0.5 years of follow-up, 68 women (10.5%) developed severe menopausal symptoms. Per 1-SD increase, higher workload (risk ratio (RR) 1.34, 95% CI 1.04 to 1.73), job strain ratio (RR 1.30, 95% CI 1.10 to 1.54) and effort-reward ratio (RR 1.23, 95% CI 0.99 to 1.51) were associated with a higher risk, whereas higher job control was protective (RR 0.78, 95% CI 0.63 to 0.97). Results were similar after additional adjustment for menopausal, marital and parental status. Domain-specific analyses showed similar associations across symptoms, strongest for physical symptom severity.</p><p><strong>Conclusions: </strong>Psychosocial work factors, particularly high workload, low job control and high job strain, were associated with the development of severe menopausal symptoms. These findings highlight the importance of psychosocial work environments in supporting women during the menopausal transition.</p>","PeriodicalId":19459,"journal":{"name":"Occupational and Environmental Medicine","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148795973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occupational exposure to noise and depression incidence: a nationwide cohort study of workers in Denmark, 2000-2017.","authors":"Anne Marie Kirkegaard, Aslak Harbo Poulsen, Zara Ann Stokholm, Henrik Albert Kolstad, Lau Caspar Thygesen, Jenny Selander, Karin Sørig Hougaard, Ida E H Madsen, Mette Sørensen","doi":"10.1136/oemed-2026-111036","DOIUrl":"https://doi.org/10.1136/oemed-2026-111036","url":null,"abstract":"<p><strong>Objectives: </strong>Research on the association between occupational noise and incident depression is limited. We investigated whether long-term occupational noise was associated with depression risk, both independently and in combination with other stress-related factors.</p><p><strong>Methods: </strong>In a Danish nationwide register-based cohort of 2 424 542 workers aged 25-64 years, individual-level occupational histories were linked to noise exposure using a job exposure matrix. Noise exposure was aggregated as 5-year running means. During follow-up from 2000 to 2017, 142 370 women and 119 900 men developed incident depression, identified through hospital and prescription registers. HRs were estimated using Cox models with adjustment for individual and area-level factors. Subgroup analyses assessed effect modification by stress-related factors.</p><p><strong>Results: </strong>A 10 dBA higher 5-year mean occupational noise (≥65 dBA) was associated with HRs (95% CIs) of 1.09 (1.07 to 1.12) for women and 1.13 (1.10 to 1.15) for men aged 25-39 years and 1.09 (1.04 to 1.14) for women aged 40-64 years. Higher risks were mainly observed among workers with low education, low to median income, blue-collar jobs or financial stress. Among men aged 40-64 years, the corresponding HR was 0.98 (0.97 to 1.00), with inverse associations mainly observed among those with high income, white-collar occupations and no financial stress.</p><p><strong>Conclusions: </strong>Long-term exposure to occupational noise seemed associated with higher depression risk among women as well as men younger than 40 years. Associations were mainly observed among workers of low socioeconomic status, suggesting that noise reduction may be particularly relevant for prevention in vulnerable worker groups.</p>","PeriodicalId":19459,"journal":{"name":"Occupational and Environmental Medicine","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148713363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reducing occupational exposure to pesticides: understanding the preventive behaviours of French farmers.","authors":"Morgane Bresson, Cécile Sénémeaud, Isabelle Baldi, Yonna Moreau, Themistoklis Apostolidis, Pierre Lebailly","doi":"10.1136/oemed-2025-110516","DOIUrl":"https://doi.org/10.1136/oemed-2025-110516","url":null,"abstract":"<p><strong>Objective: </strong>Preventing farmers' exposure to pesticides is a major public health issue. However, research on farmers' practices, particularly in high-income countries, rarely explores the combined role of sociodemographic, occupational and psychosocial factors or considers behaviours beyond the use of personal protective equipment. This study investigated pesticide risk prevention behaviours among French farmers, focusing on agricultural specialisation (ie, the main production on the farm), individual characteristics and key psychosocial determinants.</p><p><strong>Methods: </strong>A comprehensive telephone survey conducted among French winegrowers or grower-breeders probed their pesticide knowledge, psychological constructs (attitudes and perceptions, social norms and control) and individual and occupational factors. Associations with three preventive behaviours were studied separately by logistic regression.</p><p><strong>Results: </strong>162 male farmers were surveyed (median age 50, 74% with high school education), including 99 grower-breeders and 63 winegrowers, with differences in farm size, labour structure and employment status. Preventive measures were not implemented systematically: 59% wore gloves, 65% washed their hands and 45% read hazard information on labels. Agricultural specialisation was a major factor influencing behaviour as well as psychosocial determinants (self-efficacy, perceived barriers and social norms). In contrast, sociodemographic factors and knowledge levels had little effect.</p><p><strong>Conclusion: </strong>The adoption of pesticide risk prevention behaviours remains limited over time, even in high-income countries. Our study demonstrates that (1) behaviours relying on distinct determinants should be analysed separately, (2) agricultural specialisation is a major factor influencing behaviours and (3) psychosocial variables play a predominant role in behaviour adoption. This appraisal is crucial for designing an appropriate intervention targeting French farmers.</p>","PeriodicalId":19459,"journal":{"name":"Occupational and Environmental Medicine","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148648055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Principal component analysis of pre-sleep artificial light at night exposure patterns and the associations with sleep disturbances in Hong Kong shift-working nurses and daytime office workers.","authors":"Beixi Li, Yufei Liu, Wenzhen Li, Julie Y T Ma, Anke Huss, Joey Chan, Yun Kwok Wing, Lap Ah Tse","doi":"10.1136/oemed-2026-111078","DOIUrl":"https://doi.org/10.1136/oemed-2026-111078","url":null,"abstract":"<p><strong>Background: </strong>This study investigated actigraphy-measured pre-sleep artificial light at night (ALAN) exposure patterns on non-workdays and their associations with sleep parameters among Hong Kong shift-working nurses and daytime office workers.</p><p><strong>Methods: </strong>Using a 7-day actigraphy-measured longitudinal study design, we recruited 136 shift nurses and 66 matched daytime office workers (July 2022-February 2023). ALAN exposure metrics and sleep parameters were derived from actigraphy data, supplemented by sociodemographic surveys and sleep-activity diaries. Principal component analysis (PCA) was performed on log-transformed light values to identify ALAN exposure patterns; mixed-effect models analysed associations with total sleep time (TST), sleep onset latency, wake after sleep onset (WASO) and sleep timing.</p><p><strong>Results: </strong>Shift nurses were younger (34.8 vs 36.0 years), showing no significant difference in TST (6.6 vs 6.8 hours, p=0.447) compared with daytime office workers. PCA identified Light PC1 (overall intensity) and Light PC2 (temporal pattern) patterns. In the adjusted models, wrist-worn Light PC1 showed strong associations with shorter TST (β=-0.59, SE=0.08, p<0.001), reduced WASO (β=-0.20, SE=0.04, p<0.001), later sleep onset (β=0.20, SE=0.07, p=0.003) and earlier wake-up time (β=-0.65, SE=0.09, p<0.001). Bedroom Light PC1 showed similar but weaker associations (TST: β=-0.21, SE=0.09, p=0.028). Light PC2 was not significantly associated with any sleep outcomes. Sensitivity analyses confirmed PCA's model fit, and subgroup analyses revealed no significant interaction effects (all p>0.05).</p><p><strong>Conclusion: </strong>Our findings suggest sleep interventions should prioritise reducing personal light exposure before bed. Future studies could clarify the roles of specific light properties.</p>","PeriodicalId":19459,"journal":{"name":"Occupational and Environmental Medicine","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148631128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: <i>Work participation and disability pension after work-related PTSD: trajectories and impact of occupation</i>.","authors":"","doi":"10.1136/oemed-2025-110412corr1","DOIUrl":"10.1136/oemed-2025-110412corr1","url":null,"abstract":"","PeriodicalId":19459,"journal":{"name":"Occupational and Environmental Medicine","volume":"83 4","pages":"e2"},"PeriodicalIF":3.2,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13479214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148562602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parental occupational exposure to pesticides at birth and risk of adult testicular germ cell tumours in offspring: a French nationwide case-control study.","authors":"Adèle Paul, Aurélie Danjou, Astrid Coste, Hans Kromhout, Marie Lefevre, Johan Spinosi, Brigitte Dananché, Ann Olsson, Céline Lamouroux, Margot Guth, Rémi Béranger, Olivia Pérol, Helen Boyle, Christel Hersant, Vanessa Loup-Cabaniols, Segolene Veau, Jeanne Perrin, Joachim Schüz, Barbara Charbotel, Béatrice Fervers","doi":"10.1136/oemed-2024-109893","DOIUrl":"10.1136/oemed-2024-109893","url":null,"abstract":"<p><strong>Objective: </strong>To assess the association between parental occupational pesticide exposures at birth and adult testicular germ cell tumour (TGCT) by histological subtype and the agreement between two pesticide job-exposure matrices (JEM).</p><p><strong>Methods: </strong>TGCT cases (n=454) and matched controls (n=670) aged 18-45 years were recruited from 20 French university hospitals into the TESTIS national case-control study. Paternal and maternal jobs at birth were obtained from interviews of participants and their mothers/relatives and coded into official nomenclatures (International Standard Classification of Occupations, French nomenclature of activity-1999). Two complementary JEMs, ALOHA+ and FRIJEM, assessed occupational exposure to all pesticides, herbicides, insecticides, fungicides with ALOHA+ for each parent by linking job titles to JEM-derived probability and intensity estimates (no/low/high). Cohen's Kappa coefficient (κ) assessed their agreement. ORs and 95% CIs comparing exposure and levels of exposure with no exposure were estimated using conditional logistic regression adjusted for literature-based covariates statistically associated with TGCT and stratified by histological subtypes.</p><p><strong>Results: </strong>Agreement between ALOHA+and FRIJEM was moderate to substantial (κ 0.52-0.80). A statistically non-significant higher TGCT risk was observed for high paternal occupational pesticide exposure with ALOHA+ (OR 1.95, CI 0.98 to 3.84) and FRIJEM (OR 1.70, CI 0.88 to 3.28). With ALOHA+, statistically significant positive associations were seen for high paternal occupational exposure to herbicides (overall: OR 4.23, CI 1.75 to 10.22; seminomas: OR 4.78, CI 1.79 to 12.77; non-seminomas: OR 3.53, CI 1.21 to 10.3) and fungicides (overall: OR 2.09, CI 1.05 to 4.18; seminomas: OR 2.31, CI 1.02 to 5.23). No statistically significant associations were observed for other levels of paternal exposure or pesticide groups nor for maternal exposure.</p><p><strong>Conclusion: </strong>Only high paternal occupational exposure to pesticides at birth, especially herbicides and fungicides, was positively associated with TGCT.</p>","PeriodicalId":19459,"journal":{"name":"Occupational and Environmental Medicine","volume":" ","pages":"195-203"},"PeriodicalIF":3.2,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13479229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148302523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Economic burden of musculoskeletal pain in Danish senior workers: a working-life expectancy approach.","authors":"Jacob Pedersen, Kristian Schultz Hansen, Melody Almroth, Emil Sundstrup, Lars L Andersen","doi":"10.1136/oemed-2026-110952","DOIUrl":"10.1136/oemed-2026-110952","url":null,"abstract":"<p><strong>Background: </strong>Musculoskeletal pain (MSP) is a major occupational health challenge and a leading cause of disability and economic burden worldwide. However, prospective evidence on how pain intensity across multiple body regions affects long-term labour market participation and production losses remains limited. This study quantifies working-life expectancy (WLE) and working years lost (WYL) associated with multisite MSP among senior workers and introduces a novel method to estimate its related economic burden.</p><p><strong>Methods: </strong>The study includes 23 071 Danish employees aged 50-66 years from the SeniorWorkingLife study (2018 and 2022), linked to national labour-market registers through 2024. Self-reported pain intensity (low, moderate, high) in four body regions was examined. WLE and WYL were estimated using the expected labour market affiliation method, and economic costs were calculated from individual wage data.</p><p><strong>Results: </strong>Moderate-to-high pain in two body regions was associated with reduced WLE and higher production losses. Employees with high back and leg pain had mean annual losses of €8167 per person (€58.8 million total), with 38% attributable to sickness absence. Total losses linked to back and leg pain were estimated at €2.0 billion (0.5% of Denmark's GDP).</p><p><strong>Conclusion: </strong>MSP in senior workers, particularly when affecting multiple body regions, imposes a substantial economic burden through reduced WLE and increased sickness absence. Targeted interventions are needed to manage MSP and sustain employment among older workers.</p>","PeriodicalId":19459,"journal":{"name":"Occupational and Environmental Medicine","volume":" ","pages":"223-232"},"PeriodicalIF":3.2,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13479266/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148361907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}