Nigerian Journal of Clinical Practice最新文献

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Do Autonomic Nervous System and Perceived Exertion Responses Differ Between Walking and Virtual Reality-Engaged Walking? 自主神经系统和感知运动反应在步行和虚拟现实参与的步行之间有区别吗?
IF 0.7 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2025-08-01 Epub Date: 2025-08-30 DOI: 10.4103/njcp.njcp_121_25
G Demircioglu, S Ozkan
{"title":"Do Autonomic Nervous System and Perceived Exertion Responses Differ Between Walking and Virtual Reality-Engaged Walking?","authors":"G Demircioglu, S Ozkan","doi":"10.4103/njcp.njcp_121_25","DOIUrl":"https://doi.org/10.4103/njcp.njcp_121_25","url":null,"abstract":"<p><strong>Background: </strong>Walking, important for cardiovascular health and autonomic regulation, is often done on a treadmill.</p><p><strong>Aim: </strong>This study compared the physiological responses of treadmill and virtual reality walking, focusing on their effects on the autonomic nervous system, recovery, and perceived exertion.</p><p><strong>Methods: </strong>This study included 40 sedentary participants, assigned to a treadmill group (TG) or a virtual reality group (VRG). Both groups performed 20-minute treadmill walking, with the VRG additionally using the Wii Fit program. Autonomic assessments with the Polar H10 measured heart rate (HR), parasympathetic nervous system (PNS), sympathetic nervous system (SNS), stress index (SI), and the LF/HF ratio. At the same time, perceived exertion was assessed using the OMNI scale. Physiological responses were measured at baseline (T0), post exercise (T1), and at 10 (T2) and 30 minutes (T3) of recovery.</p><p><strong>Results: </strong>The study showed significant differences in HR (P = 0.040) and LF/HF (P = 0.038) between T0-T1 in the TG. In the VRG, significant changes were found in HR (P = 0.016), SNS (P = 0.010), SI (P = 0.014), and LF/HF (P = 0.020) between T0-T1, with an additional difference in LF/HF at T0-T2 (P = 0.032). OMNI scores significantly differed at all time points (P < 0.05). No significant differences were found between groups in autonomic parameters or OMNI scores (P > 0.05).</p><p><strong>Conclusion: </strong>Although perceived exertion was similar, the VR group showed greater SNS activation due to immersion, while recovery was identical for both methods. This understanding could contribute to developing rehabilitation strategies considering autonomic VR responses.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 8","pages":"969-977"},"PeriodicalIF":0.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and Validation of a Novel 13-Gene Prognostic Model for Pediatric Acute Lymphoblastic Leukemia. 儿童急性淋巴细胞白血病13基因预后模型的建立与验证
IF 0.7 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2025-08-01 Epub Date: 2025-08-30 DOI: 10.4103/njcp.njcp_26_25
L Luo, G Tan
{"title":"Development and Validation of a Novel 13-Gene Prognostic Model for Pediatric Acute Lymphoblastic Leukemia.","authors":"L Luo, G Tan","doi":"10.4103/njcp.njcp_26_25","DOIUrl":"https://doi.org/10.4103/njcp.njcp_26_25","url":null,"abstract":"<p><strong>Background: </strong>Pediatric acute lymphoblastic leukemia (ALL) arises from B- or T-lineage lymphoid progenitors is the most common form of childhood cancer.</p><p><strong>Aim: </strong>This study aimed to develop a prognostic signature for overall survival (OS) in pediatric ALL patients.</p><p><strong>Methods: </strong>Pediatric ALL driver genes were used for LASSO-Cox regression to construct a prognostic model in a training cohort (GDC TARGET-ALL-P2, n = 103). The model's performance was assessed and validated in an independent cohort (GDC MP2PRT-ALL, n = 132).</p><p><strong>Results: </strong>Thirteen genes out of 367 potential driver genes associated with ALL were selected for model construction. In the training cohort, the model has AUC values of 0.73, 0.89, and 0.832 at 365, 1,095 and 1,825 days, respectively. High-risk patients had significantly worse OS (hazard Ratio, HR = 10.87, 95% CI: 5.93-19.95, P < 0.001). In the invalidation cohort, it has an AUC value of 0.82 at 365 days and an HR of 3.048 (95% CI: 1.780-5.219, P < 0.001).</p><p><strong>Conclusion: </strong>This study identifies a 13-gene signature as a promising tool for risk stratification in pediatric ALL.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 8","pages":"946-954"},"PeriodicalIF":0.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Comparison of Otological Disorders among Children Attending Selected Urban and Rural Primary Schools in Enugu. 埃努古选定城市和农村小学就读儿童耳科疾病患病率及比较
IF 0.7 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2025-07-01 Epub Date: 2025-07-28 DOI: 10.4103/njcp.njcp_646_24
J O Akpeh, U C Nze, B C Ezeanolue
{"title":"Prevalence and Comparison of Otological Disorders among Children Attending Selected Urban and Rural Primary Schools in Enugu.","authors":"J O Akpeh, U C Nze, B C Ezeanolue","doi":"10.4103/njcp.njcp_646_24","DOIUrl":"10.4103/njcp.njcp_646_24","url":null,"abstract":"<p><strong>Background: </strong>Diseases of the ear remain the commonest otorhinolaryngological disease among children. When left unattended to, can impact negatively on the child's general well-being, academic performance, life potentials and integration into the society.</p><p><strong>Aim: </strong>To determine the prevalence and pattern of otological diseases among school-aged children, and compare the prevalence between the urban and the rural school children's populations.</p><p><strong>Patients and methods: </strong>A cross-sectional study of 385 school children randomly selected from rural and urban primary schools in Enugu state, Nigeria. The clinical presentations, otological examination findings, and overall diagnosis were recorded. Data analysis was both descriptive and inferential using the statistical packages for social sciences (SPSS) version 26 for windows, at 95% confidence level.</p><p><strong>Results: </strong>A total of 83 pupils (21.56%) had different ear diseases. The commonest presenting complaint was ear itching (11.4%), followed by hearing loss (7.5%), while the least presenting complaints were dizziness and foreign body impactions. Most pupils had type A tympanogram (94.3%) and normal hearing on audiometry (83.9%). The commonest ear pathology was cerumen impaction (30.9%). The pattern of presentation, physical findings and clinical diagnosis were largely similar between the rural and urban populations (P < 0.05).</p><p><strong>Conclusion: </strong>Otological diseases are common among school children in both rural and urban areas. They can be easily identified and prevented by routine screening and follow-up to help reduce the long-term sequelae.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 7","pages":"831-837"},"PeriodicalIF":0.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiologic Follow-up of Vascular Structures in Gastric Cancer Patients Receiving Adjuvant Radiotherapy. 胃癌辅助放疗患者血管结构的影像学随访。
IF 0.7 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2025-07-01 Epub Date: 2025-07-28 DOI: 10.4103/njcp.njcp_229_25
F Karaca, S Keskin, H Akkaya, S Menteş, S Altıntas, A Z Bayhan, T Çil, B Gülek
{"title":"Radiologic Follow-up of Vascular Structures in Gastric Cancer Patients Receiving Adjuvant Radiotherapy.","authors":"F Karaca, S Keskin, H Akkaya, S Menteş, S Altıntas, A Z Bayhan, T Çil, B Gülek","doi":"10.4103/njcp.njcp_229_25","DOIUrl":"10.4103/njcp.njcp_229_25","url":null,"abstract":"<p><strong>Background and aim: </strong>This study aimed to examine the changes in vascular structures due to radiotherapy (RT) in patients who received adjuvant RT and chemotherapy with the diagnosis of gastric cancer.</p><p><strong>Materials and methods: </strong>Thirty-three patients receive curative doses of adjuvant external RT. The changes in the diameters of the portal vein (PV) and celiac artery (CA) in mm in computed tomography were examined before RT (RT0) and 3 months after RT (RT1).</p><p><strong>Results: </strong>The RT1-PV value decreases by 0.31 mm when compared to the RT0 value (P < 0.05). Likewise, the CA measurements too showed a decrease by 0.24 mm, when the RT0 and RT1 values were compared.</p><p><strong>Conclusion: </strong>In this study, the measurements of the CA and PV in mm at time RT1 were smaller than their measurements at time RT0.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 7","pages":"848-853"},"PeriodicalIF":0.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of the Presence or Eradication of Helicobacter pylori on Weight Loss in Patients Undergoing Laparoscopic Sleeve Gastrectomy due to Obesity: A Retrospective Study. 幽门螺杆菌的存在或根除对肥胖腹腔镜袖胃切除术患者体重减轻的影响:一项回顾性研究
IF 0.7 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2025-07-01 Epub Date: 2025-07-28 DOI: 10.4103/njcp.njcp_165_24
A Çekiç, E Oymacı, A M Öztürk, S Tan, Ö Çağlıyan, A C Yaşar, M Yildirim
{"title":"Effect of the Presence or Eradication of Helicobacter pylori on Weight Loss in Patients Undergoing Laparoscopic Sleeve Gastrectomy due to Obesity: A Retrospective Study.","authors":"A Çekiç, E Oymacı, A M Öztürk, S Tan, Ö Çağlıyan, A C Yaşar, M Yildirim","doi":"10.4103/njcp.njcp_165_24","DOIUrl":"10.4103/njcp.njcp_165_24","url":null,"abstract":"<p><strong>Background: </strong>The efficacy of laparoscopic sleeve gastrectomy (LSG) has been demonstrated in the treatment of obesity. No studies have evaluated the effect of Helicobacter pylori (H. pylori) eradication on weight loss in patients undergoing LSG. Considering the prevalence of H. pylori infection, we think that the majority of the H. pylori-negative patients in studies investigating this association actually consisted of patients who had been eradicated.</p><p><strong>Aim: </strong>We aimed to evaluate the possible relationship between the presence and eradication of H. pylori preoperatively and based on weight data after LSG.</p><p><strong>Methods: </strong>A total of 191 (58%) patients with available pre- and postoperative H. pylori data and regular follow-up records were included among 329 patients who underwent LSG for obesity. The H. pylori positive, negative, and eradicated groups were evaluated. Preoperative body mass index (BMI) and postoperative data, the time to reach the lowest weight, the lowest BMI achieved, the current BMI, the maximum percentage of excess weight loss (EWL%), the current EWL%, and follow-up data were compared.</p><p><strong>Results: </strong>A total of 118 (61.8%) of the patients were H. pylori positive preoperatively, and 40 (20.9%) were positive postoperatively. According to their H. pylori status, 73 (38.2%) patients were negative, 78 (40.8%) were eradicated, and 40 (21%) were positive. According to the three-group analyses, no statistically significant relationship was found between the H. pylori infection status or weight and time.</p><p><strong>Conclusion: </strong>We found that the preoperative presence, absence, or eradication of H. pylori did not affect the time needed to reach the lowest weight after the operation, the lowest BMI achieved, the current BMI, the maximum EWL%, or the current EWL% in patients who underwent LSG for obesity.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 7","pages":"824-830"},"PeriodicalIF":0.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is ChatGPT-4o an Effective Tool for Providing Accurate Responses to Frequently Asked Questions by Varicocele Patients? chatggt - 40是精索静脉曲张患者提供准确回答常见问题的有效工具吗?
IF 0.7 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2025-07-01 Epub Date: 2025-07-28 DOI: 10.4103/njcp.njcp_61_25
M Karaaslan, I Dalva, H Akan, M E Sirin, S Tonyali, M Yilmaz
{"title":"Is ChatGPT-4o an Effective Tool for Providing Accurate Responses to Frequently Asked Questions by Varicocele Patients?","authors":"M Karaaslan, I Dalva, H Akan, M E Sirin, S Tonyali, M Yilmaz","doi":"10.4103/njcp.njcp_61_25","DOIUrl":"10.4103/njcp.njcp_61_25","url":null,"abstract":"<p><strong>Background: </strong>Varicocele is a common cause of male infertility. Recently, AI tools like ChatGPT have become popular sources of health information among patients.</p><p><strong>Aim: </strong>We aimed to investigate the effectiveness of ChatGPT-4o in addressing frequently asked questions (FAQs) about varicocele.</p><p><strong>Methods: </strong>The study included 39 questions, comprising 33 FAQs and 6 questions based on the 2024 guidelines of the European Association of Urology (EAU). The responses provided by ChatGPT-4o were evaluated by two urology specialists for their quality and reliability using the Global Quality Score (GQS). The reproducibility of the responses was analyzed by asking each question twice on different days.</p><p><strong>Results: </strong>ChatGPT-4o provided high-quality and comprehensive responses (GQS 5) to 30.7% of the questions, good-quality responses (GQS 4) to 59%, and insufficiently comprehensive and moderate-quality responses (GQS 3) to 10.3%. The reproducibility of responses varied, with general questions about varicocele and EAU guideline-based questions showing 83.3% reproducibility, specific questions about varicocele showing 100%, and treatment-related questions showing 76.5%.</p><p><strong>Conclusion: </strong>This study demonstrates that ChatGPT-4o is a valuable tool in providing information about varicocele, with a high overall success rate in terms of accuracy and reliability. However, it is important to note the lack of excellence in the design of some responses and the low reproducibility of answers, particularly for treatment-related questions.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 7","pages":"810-815"},"PeriodicalIF":0.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Macular Microvascular Alterations and Visual Outcomes Following Successful Retinal Detachment Surgery in a Sub-Saharan African Context. 在撒哈拉以南非洲地区,视网膜脱离手术成功后黄斑微血管改变和视力结果。
IF 0.7 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2025-07-01 Epub Date: 2025-07-28 DOI: 10.4103/njcp.njcp_881_24
O Oderinlo, O Idris, L Oshunkoya, A O Hassan
{"title":"Macular Microvascular Alterations and Visual Outcomes Following Successful Retinal Detachment Surgery in a Sub-Saharan African Context.","authors":"O Oderinlo, O Idris, L Oshunkoya, A O Hassan","doi":"10.4103/njcp.njcp_881_24","DOIUrl":"10.4103/njcp.njcp_881_24","url":null,"abstract":"<p><strong>Background: </strong>Retinal detachment disrupts blood flow and oxygenation, potentially causing persistent microvascular damage even after successful reattachment surgery. This study retrospectively evaluates macular microvascular changes using Optical Coherence Tomography (OCT) and Optical Coherence Tomography Angiography (OCTA) and explores their relationship with visual function in patients following successful retinal detachment surgery (RDS).</p><p><strong>Aim: </strong>To report macular microvascular changes using optical coherence tomography and optical coherence tomography angiography (OCTA) and their relationship with visual function in patients following successful retinal detachment surgery (RDS).</p><p><strong>Methods: </strong>A retrospective review of medical records was conducted for patients who underwent rhegmatogenous retinal detachment (RRD) surgery at the Eye Foundation Hospital, Lagos, Nigeria, between January 2022 and December 2022. Patients meeting predefined inclusion criteria were included in the analysis.</p><p><strong>Results: </strong>Data from 64 eyes of 38 patients were analyzed, while 12 contralateral eyes were excluded. Postoperative visual acuity improved significantly compared to preoperative levels (P = 0.018). The mean central retinal thickness (CRT) in operated eyes was 292.7 ± 161.0 µm, significantly greater than the control group (235.6 ± 14.0 µm, P = 0.036). Macula-on RRD cases achieved better visual outcomes (63.6%) compared to macula-off cases (36.4%, P = 0.024). The foveal avascular zone (FAZ) area in both the superficial capillary plexus and deep capillary plexus was significantly larger in control eyes (0.31 ± 0.11 mm²) compared to eyes with acceptable visual outcomes (0.26 ± 0.11 mm²) and those without (0.22 ± 0.11 mm², P = 0.017). Eyes with acceptable visual outcomes had a higher proportion of continuous external limiting membrane (ELM) (90.9%) and ellipsoid zone (EZ) (90.9%) compared to eyes without acceptable outcomes (ELM: 55.6%, EZ: 77.8%), though these differences were not statistically significant (P = 0.075 and P = 0.556, respectively). Mean superficial and deep foveal vessel density showed no significant difference between groups.</p><p><strong>Conclusion: </strong>Macula microvascular changes significantly influence visual recovery after RDS. Parameters such as subfoveal CRT and FAZ area are key predictors of visual outcomes, while outer subfoveal retinal features like ELM and EZ integrity improve over time. Early intervention, coupled with OCTA monitoring, can optimize postoperative care and predict visual outcomes. This study underscores the importance of macular integrity and preoperative visual acuity in achieving favorable long-term visual function.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 7","pages":"803-809"},"PeriodicalIF":0.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluatıng the Role of Overactıve Bladder Dıagnosıs ın Predıctıng the Rısk of Postspınal Hypotensıon Durıng Electıve Cesarean Sectıon Operatıons: Randomızed Trıple-Blınded Study.
IF 0.7 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2025-07-01 Epub Date: 2025-07-28 DOI: 10.4103/njcp.njcp_680_24
A Dostbil, K Kasali, Gnc Senocak, I Ince, F Ozkaya, M S Ozkal, C Atalay, M Aksoy, Irfan Uc, F A Akbulut
{"title":"Evaluatıng the Role of Overactıve Bladder Dıagnosıs ın Predıctıng the Rısk of Postspınal Hypotensıon Durıng Electıve Cesarean Sectıon Operatıons: Randomızed Trıple-Blınded Study.","authors":"A Dostbil, K Kasali, Gnc Senocak, I Ince, F Ozkaya, M S Ozkal, C Atalay, M Aksoy, Irfan Uc, F A Akbulut","doi":"10.4103/njcp.njcp_680_24","DOIUrl":"10.4103/njcp.njcp_680_24","url":null,"abstract":"<p><strong>Background: </strong>It is important to predict hypotension following spinal anesthesia (SA) during cesarean section (C/S), in terms of preventing the adverse affects.</p><p><strong>Aim: </strong>The aim of this study is to evaluate diagnosing overactive bladder via the overactive bladder (OAB)-V8 questionnaire that could be a prediction method for postspinal hypotension during elective cesarean section under combined spinal-epidural anesthesia.</p><p><strong>Materials and methods: </strong>This study was carried out on 143 primipara women in the third trimester planned for elective cesarean section under combined spinal-epidural anesthesia. Each primipara parturient in her third trimester was seen by a urology specialist for diagnosis before surgery, where she was directed to the OAB-V8 questionnaire in Turkish. Patients diagnosed with overactive bladder were recorded under Group I, and the others under Group II.</p><p><strong>Results: </strong>39,9% of patients had hypotension. Hypotension occurrence was statistically higher in Group I than in Group II (47% vs 30%). According to the diagnostic test results for using overactive bladder diagnosis in the prediction of hypotension, the sensitivity was 68%, the specificity was 49%, positive predictive values were 47%, and negative predictive values were 70%.</p><p><strong>Conclusion: </strong>The risk of postspinal hypotension in parturients with overactive bladder is higher. Higher caution must be taken for hypotension after SA intervention in patients with over active bladder.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 7","pages":"797-802"},"PeriodicalIF":0.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Circadian Rhythm on Hypotension During Spinal Anesthesia for Cesarean Delivery: A Prospective Observational Study. 剖宫产脊柱麻醉期间昼夜节律对低血压的影响:一项前瞻性观察研究。
IF 0.7 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2025-07-01 Epub Date: 2025-07-28 DOI: 10.4103/njcp.njcp_195_25
M Sari, M Sargin, F Okucu
{"title":"Impact of Circadian Rhythm on Hypotension During Spinal Anesthesia for Cesarean Delivery: A Prospective Observational Study.","authors":"M Sari, M Sargin, F Okucu","doi":"10.4103/njcp.njcp_195_25","DOIUrl":"10.4103/njcp.njcp_195_25","url":null,"abstract":"<p><strong>Background: </strong>Spinal anesthesia (SA) is the preferred method for cesarean delivery, though it is often associated with maternal hypotension. Predicting hypotension can enhance clinical decision-making, optimize management strategies, and improve patient outcomes.</p><p><strong>Aim: </strong>We aimed to test the association between circadian rhythm and the incidence of hypotension during spinal anesthesia for cesarean delivery.</p><p><strong>Patients and methods: </strong>This prospective observational study included women undergoing cesarean delivery with spinal anesthesia, excluding those with inadequate anesthesia or major comorbidities. Patients were divided into morning (6:00-12:00) and afternoon (12:00-18:00) groups based on C-section time. Hemodynamic variables, total ephedrine dosage, and incidence of nausea, vomiting, and hypotension were assessed, with hypotension as the primary outcome.</p><p><strong>Results: </strong>Out of 231 screened patients, 203 were enrolled, and 200 patients were analyzed. 114 were allocated to Group morning and 86 to Group afternoon. The overall incidence of hypotension was 66%, with severe hypotension occurring at a significantly higher rate in the morning group compared to the afternoon group (43% vs. 30.2%, P = 0.028).</p><p><strong>Conclusion: </strong>Our findings suggest that the timing of cesarean delivery may influence the incidence of spinal anesthesia-induced hypotension, underscoring the potential clinical value of considering circadian factors when scheduling procedures to optimize maternal hemodynamic stability.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 7","pages":"790-796"},"PeriodicalIF":0.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laparoscopic Hernia Repair Using the Totally Extraperitoneal Procedure with Mesh: A Retrospective Study at a Tertiary Care Hospital in Vietnam. 全腹膜外补片腹腔镜疝修补:越南一家三级医院的回顾性研究
IF 0.7 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2025-07-01 Epub Date: 2025-07-28 DOI: 10.4103/njcp.njcp_255_24
T Q Son, T M Hung, T H Hoc, N P Anh, D T Anh, V D Vinh, V Q Huy, Vtp Anh
{"title":"Laparoscopic Hernia Repair Using the Totally Extraperitoneal Procedure with Mesh: A Retrospective Study at a Tertiary Care Hospital in Vietnam.","authors":"T Q Son, T M Hung, T H Hoc, N P Anh, D T Anh, V D Vinh, V Q Huy, Vtp Anh","doi":"10.4103/njcp.njcp_255_24","DOIUrl":"10.4103/njcp.njcp_255_24","url":null,"abstract":"<p><strong>Background: </strong>In the last 30 years, two revolutions have occurred in inguinal hernia repair surgery. In 1989, Liechtenstein launched tension-free hernia treatment, and in the early 1990s, laparoscopic surgery was used to treat inguinal hernias.</p><p><strong>Aim: </strong>This study evaluated the safety and efficacy of laparoscopic totally extraperitoneal (TEP) inguinal and femoral hernia repair.</p><p><strong>Methods: </strong>This retrospective study of 182 patients treated using the TEP technique at Bachmai Hospital from January 2020 to December 2023 was done. Patient demographic data, peri-operative, and outpatient follow-up were studied.</p><p><strong>Results: </strong>The study examined 207 hernia repairs. Patients were 99.4% male. The median age was 59 (18-85) of the 167 primary hernia patients. The average operation time for bilateral inguinal hernias was longer than for unilateral (86.3 vs 53.6 minutes). The conversion rates to transabdominal preperitoneal (TAPP) repair and open surgery were 1.1% and 0.55%, respectively. Epigastric artery injury, port site infection, hematoma, and seroma were 1.09%, 1.6%, 0.55%, and 10.9%, respectively. The average hospital stay was 3.2 days (1-8 days). Two patients who developed recurrence were dealt with open mesh repair.</p><p><strong>Conclusion: </strong>The TEP method is safe, feasible, and effective for treating inguinal hernias.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 7","pages":"777-782"},"PeriodicalIF":0.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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