Alexandra Jones ⁎, , Damian Maganja , Maria Shahid , Bruce Neal , Simone Pettigrew
{"title":"Uptake of voluntary versus mandatory food labels: A natural experiment in Australia","authors":"Alexandra Jones ⁎, , Damian Maganja , Maria Shahid , Bruce Neal , Simone Pettigrew","doi":"10.1016/j.orcp.2024.09.037","DOIUrl":"10.1016/j.orcp.2024.09.037","url":null,"abstract":"","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 5","pages":"Page S16"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142327790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cathy Kwok , Louise A Baur , Eve T House , Kaitlin Day , Megan Gow , Mary Kate Inkster , Sarah Lang , Natalie B Lister , Hiba Jebeile ⁎,
{"title":"Characterising support needs of adolescents with obesity participating in a dietary intervention","authors":"Cathy Kwok , Louise A Baur , Eve T House , Kaitlin Day , Megan Gow , Mary Kate Inkster , Sarah Lang , Natalie B Lister , Hiba Jebeile ⁎,","doi":"10.1016/j.orcp.2024.09.046","DOIUrl":"10.1016/j.orcp.2024.09.046","url":null,"abstract":"","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 5","pages":"Pages S19-S20"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142326543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aman Juneja ⁎, , Kate McBride , Patrick Tran , Milan Piya
{"title":"Barriers to accessing a public hospital multidisciplinary weight management program for women with class 3 obesity","authors":"Aman Juneja ⁎, , Kate McBride , Patrick Tran , Milan Piya","doi":"10.1016/j.orcp.2024.09.048","DOIUrl":"10.1016/j.orcp.2024.09.048","url":null,"abstract":"","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 5","pages":"Page S20"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142327303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Miluse Vozdova, Svatava Kubickova, Vera Kopecka, Jaroslav Sipek, Jiri Rubes
{"title":"Effect of body mass index on semen quality, sperm chromatin integrity and sperm DNA methylation","authors":"Miluse Vozdova, Svatava Kubickova, Vera Kopecka, Jaroslav Sipek, Jiri Rubes","doi":"10.1016/j.orcp.2024.09.276","DOIUrl":"10.1016/j.orcp.2024.09.276","url":null,"abstract":"<div><div>Obesity represents a growing problem due to its impacts on human health and reproduction. In this study, we analysed semen quality, sperm DNA integrity and gene-specific CpG methylation in 116 healthy men from normal population. The men were divided into three groups according to their body mass index (BMI), and their ejaculates were analysed using standard methods, sperm chromatin structure assay (SCSA), methylation next generation sequencing (NGS) and amplicon sequencing. The sperm methylation NGS revealed six significantly differentially methylated regions (DMRs). Using subsequent targeted amplicon sequencing in 116 men, two of the DMRs were proved as differentially methylated in sperm of men with normal BMI vs. BMI ≥ 25. The DMRs were located in the <em>EPHA8</em> and <em>ANKRD11</em> gene. Also, we detected a significant decline in the <em>EPHA8, ANKRD11</em> and <em>CFAP46</em> gene methylation in association with increasing BMI values. The genes <em>EPHA8</em> and <em>ANKRD11</em> are involved in the nervous system and brain development; the <em>CFAP46</em> gene plays a role in a flagellar assembly and is associated with sperm motility. Significantly lower rates of motile and progressive motile sperm were observed in men with BMI ≥ 30. Our results show that excess body weight can modify CpG methylation of specific genes, affect sperm motility, and compromise sperm chromatin integrity. These factors can stand behind the observed reduced fertility in men with obesity. The methylation changes might be transmitted to their offspring through sperm, and become a basis for possible developmental and reproductive issues in the next generation.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 5","pages":"Pages 380-387"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ke Han , Xiangyao Wang , Xiaotong Niu , Tian Li , Enqiang Linghu
{"title":"Prevalence and associated factors of chronic diarrhea among adults with obesity in the United States: Evidence from the National Health and Nutrition Examination Survey 2005 to 2010","authors":"Ke Han , Xiangyao Wang , Xiaotong Niu , Tian Li , Enqiang Linghu","doi":"10.1016/j.orcp.2024.11.002","DOIUrl":"10.1016/j.orcp.2024.11.002","url":null,"abstract":"<div><h3>Objective</h3><div>Diarrhea in populations with obesity is underappreciated and factors associated with chronic diarrhea in individuals with obesity have not been studied. We aimed to analyze the prevalence of chronic diarrhea and associated factors among adults with obesity in a nationally representative population.</div></div><div><h3>Methods</h3><div>Data of adults with obesity in the National Health and Nutrition Examination Survey (NHANES) during 2005–2010 were analyzed. Chronic diarrhea was defined according to the Bristol Stool Form Scale. Demographic, lifestyle, dietary, and metabolic factors were considered. Prevalence estimates were described by group, and odds ratios (ORs) for associated factors were calculated in multivariate logistic regression.</div></div><div><h3>Results</h3><div>Overall, 5048 respondents with obesity (weighted sample, 63,493,500) completed the bowel health questionnaire and met eligibility criteria. The chronic diarrhea prevalence in adults with obesity was 8.18 % (95 % confidence interval [CI], 7.17 %, 9.19 %). Female sex, older age, obesity severity, high dietary sugar intake, depression, and history of diabetes or prediabetes were positively correlated with chronic diarrhea. Differences occurred in the distribution of associated factors between males and females.</div></div><div><h3>Conclusion</h3><div>The overall chronic diarrhea prevalence in adults with obesity was 8.18 % in the nationally representative US population. We identified sex differences in associated demographic, dietary, and metabolic factors with chronic diarrhea in adults with obesity.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 5","pages":"Pages 328-335"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142695670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamad Gholizade , Maryam Marzban , Akram Farhadi , Hadith Tangestani , Mehdi Mahmudpour , Katerina Trajanoska , Elnaz Shabankari , Sadaf Rezaie , Mohammad Mehdi Khaleghi , Azam Amini , Iraj Nabipour , Mohammadreza Kalantarhormozi , Hadi Emamat , Afshin Ostovar , Bagher Larijani , Amir Hossein Darabi
{"title":"Association of different obesity indices with nephrolithiasis in community-dwelling older adults","authors":"Mohamad Gholizade , Maryam Marzban , Akram Farhadi , Hadith Tangestani , Mehdi Mahmudpour , Katerina Trajanoska , Elnaz Shabankari , Sadaf Rezaie , Mohammad Mehdi Khaleghi , Azam Amini , Iraj Nabipour , Mohammadreza Kalantarhormozi , Hadi Emamat , Afshin Ostovar , Bagher Larijani , Amir Hossein Darabi","doi":"10.1016/j.orcp.2024.11.003","DOIUrl":"10.1016/j.orcp.2024.11.003","url":null,"abstract":"<div><h3>Background and objective</h3><div>Obesity has been linked to various conditions, including nephrolithiasis. Given the rising prevalence of both nephrolithiasis and obesity in older adults, this study aimed to examine the association of different obesity-related indices with nephrolithiasis.</div></div><div><h3>Methods</h3><div>This cross-sectional study included 2419 individuals (mean age 69.34 ± 6.40; 51.92 % female) from the Bushehr Elderly Health (BEH) program, a population-based measured using Dual-energy X-ray absorptiometry (DXA), while nephrolithiasis history was assessed through medical records. The associations between obesity-related indices and nephrolithiasis were analyzed using multivariable logistic regression models, adjusted for relevant confounders.</div></div><div><h3>Results</h3><div>Among the 2419 participants, 212 (8.76 %) had a history of nephrolithiasis. In the overall population, only the android-to-gynoid fat mass (FM) ratio was significantly associated with nephrolithiasis (odds ratio [OR] 3.28, 95 % Confidence Interval [CI] 1.06–10.18). In females, the trunk-to-limb FM ratio (OR 2.62, 95 % CI 1.10–6.23) and the visceral adipose index (VAI) (OR 1.092, 95 % CI 1.005–1.187) were associated with nephrolithiasis. In males, only the body adipose index (BAI) was significantly associated with nephrolithiasis (OR 1.082, 95 % CI 1.017–1.151).</div></div><div><h3>Conclusion</h3><div>In this study, the android-to-gynoid FM ratio in the total population, the trunk-to-limb FM ratio and VAI in females, and BAI in males were significantly associated with nephrolithiasis. Monitoring and managing these indices may enhance quality of life for elderly individuals by facilitating early diagnosis of nephrolithiasis and preventing stone formation.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 5","pages":"Pages 371-379"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142770972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}