Obesity research & clinical practice最新文献

{"title":"Circulating levels of Meteorin-like protein are independently linked to insulin resistance and carotid intima-media thickness in individuals with nonalcoholic fatty liver disease","authors":"Samaneh Mohassel Azadi,&nbsp;Reza Fadaei,&nbsp;Fataneh Esmaeili,&nbsp;Hossein Poustchi,&nbsp;Amir Reza Radmard,&nbsp;Amaneh Shayanrad,&nbsp;Solaleh Emamgholipour,&nbsp;Mahmood Doosti","doi":"10.1016/j.orcp.2026.04.010","DOIUrl":"10.1016/j.orcp.2026.04.010","url":null,"abstract":"<div><h3>Introduction</h3><div>Meteorin–like protein (Metrnl) is a newly discovered adipokine that affects lipid and glucose metabolism and insulin signaling. The present study aimed to measure serum Metrnl levels in nonalcoholic fatty liver disease (NAFLD) patients with and without type 2 diabetes mellitus (T2DM) and investigate its association with carotid intima–media thickness (cIMT), a clinical marker of atherosclerosis.</div></div><div><h3>Methods</h3><div>Patients with NAFLD (n = 66), patients with NAFLD+T2DM (n = 66), and healthy individuals (n = 65) were included in this case-control study. Serum levels of Metrnl and adiponectin were determined via ELISA. cIMT and liver stiffness (LS) were also assessed in all participants.</div></div><div><h3>Results</h3><div>Compared with controls, patients with NAFLD+T2DM had lower levels of adiponectin, which was accompanied by a lower level of Metrnl (<em>P</em> &lt; 0.001). Furthermore, multinomial logistic regression revealed that serum Metrnl was associated with NAFLD and NAFLD+T2DM. This association remained statistically significant even after adjustment for either body mass index (BMI) or Homeostasis Model Assessment of Insulin Resistance (HOMA-IR). Pearson’s correlation analysis in the patient group revealed significant inverse correlation between Metrnl levels and BMI, cIMT, insulin, and HOMA-IR. After adjustment for correlated factors in the patient group, multiple linear regression showed that multiple linear regression showed that BMI, carotid IMT, and HOMA-IR were independently associated with serum Metrnl levels. Moreover, Metrnl levels were lower in individuals with cIMT≥ 0.8 mm compared to those with cIMT&lt; 0.8 mm.</div></div><div><h3>Conclusions</h3><div>The results of the present study indicated that the relationship between decreased Metrnl levels and NAFLD and T2DM could be related to obesity and IR. However, further studies are necessary to establish this concept.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"20 4","pages":"Pages 285-292"},"PeriodicalIF":2.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147856851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changing internal medicine residents’ attitudes towards managing people with obesity using an interactive educational session with lecture and embedded real-life patients’ experiences","authors":"Ellina Lytvyak,&nbsp;Nikita Mittal,&nbsp;Jennie Wei,&nbsp;Tuo Lin,&nbsp;Kun Yang,&nbsp;Xin M. Tu,&nbsp;Ottar Lunde,&nbsp;Evelyn Ross,&nbsp;Jessica Cheng,&nbsp;Jennifer DeConde,&nbsp;Neil Farber,&nbsp;Eduardo Grunvald","doi":"10.1016/j.orcp.2026.05.001","DOIUrl":"10.1016/j.orcp.2026.05.001","url":null,"abstract":"<div><h3>Background</h3><div>Weight bias and discrimination towards individuals with obesity among healthcare professionals are associated with inferior patient care and worse health and healthcare outcomes. Our aim was to assess/measure the effect of an innovative interactive educational session on attitudes toward perceived causes of obesity and treating individuals with obesity among internal medicine residents.</div></div><div><h3>Methods</h3><div>This pre-post-intervention study was conducted among 30 internal medicine residents. The session included a a didactic lecture addressing the etiology, pathophysiology and management of obesity embedded with shared real-life patient experiences. Validated surveys were offered pre- and post-session: Perceived Causes of Obesity (categorized into physiological, behavioral and environmental domains) and Attitudes about Treating Patients with Obesity (negative and positive attitudes domains). A generalized estimating equations time-based model was used.</div></div><div><h3>Results</h3><div>Median age of participants was 29 years old, 53.3% females, and over half (56.7%) Caucasians. The effect of session was significant in the physiological causes domain (3.59 ± 0.75–3.97 ± 0.80; p = 0.002), suggesting significantly greater belief that obesity is caused by physiological characteristics. Our educational session also resulted in statistically significant improvement in negative attitudes about treating patients with obesity (2.43 ± 0.60–2.28 ± 0.54; p = 0.015).</div></div><div><h3>Conclusion</h3><div>Our study demonstrated significant positive impact of combining a traditional didactic lecture approach with embedded real-life patient experiences on better understanding of factors contributing to obesity and improving their attitudes towards managing this complex category of patients. Our findings merit further research on optimal strategy, context, duration, and evaluation of educational interventions that effectively and efficiently reduce weight bias among our future healthcare workforce.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"20 4","pages":"Pages 345-351"},"PeriodicalIF":2.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147869162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bariatric surgery and its impact on hemodialysis: A retrospective cohort analysis","authors":"Nicharee Sangdurn,&nbsp;Dev Jegatheesan,&nbsp;Nicole Isbel,&nbsp;Marguerite Conley,&nbsp;Lorraine Garry,&nbsp;Rebecca Healy,&nbsp;Dharmenaan Palamuthusingam,&nbsp;Shaun Chandler","doi":"10.1016/j.orcp.2026.05.008","DOIUrl":"10.1016/j.orcp.2026.05.008","url":null,"abstract":"<div><h3>Aim</h3><div>To evaluate metabolic and dialysis parameters following bariatric surgery in prospective kidney transplant candidates.</div></div><div><h3>Background</h3><div>Bariatric surgery has been associated with improved survival among patients receiving dialysis. However, the mechanism to explain this observation remains unclear, especially considering higher body mass index (BMI) has been associated with improved survival on dialysis (“Obesity Paradox”) Clarifying how surgery impacts interdialytic weight gain (IDWG), and cardiovascular risk factors, such as systolic blood pressure (SBP) and diabetes is essential.</div></div><div><h3>Methods</h3><div>All adult patients receiving dialysis who underwent bariatric surgery were identified via the Queensland Statewide Bariatric Service. Demographics, co-morbidities, weight, height, and dialysis parameters (pre-dialysis SBP, intradialytic weight gain (IDWG), and calculated ultrafiltration volume) were collected over a three-month pre-surgery and six-month post-surgery from the medical records. Paired T-Tests and Wilcoxon Signed Rank Tests were used as appropriate.</div></div><div><h3>Results</h3><div>Thirteen patients (mean age 50.3 years; 61.5% female; all on haemodialysis) were identified. Most had type 2 diabetes mellitus (61.5%) and no one had coronary artery disease. Preoperative mean weight and BMI were 129.2 kg and 44.2 kg/m², respectively. Post-operatively, patients lost an average of 29.6 kg (22.9% reduction,95%CI 19.09–40.05) and reduced BMI by 10.4 kg/m² (23.5% reduction,95%CI 6.46–14.32) SBP decreased by 14.2 mmHg (10.3% reduction) (p &lt; 0.001), and IDWG dropped by 1.16 kg (55.5% reduction) (p &lt; 0.001). Calculated ultrafiltration requirements declined by 47.7% (p &lt; 0.001). No significant changes were observed in HbA1c, antihypertensive use, or admissions for fluid overload.</div></div><div><h3>Conclusion</h3><div>Bariatric surgery was associated with significant improvements in fluid management and blood pressure control in this small cohort. Larger studies are needed to confirm the consistency and generalisability of these findings.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"20 4","pages":"Pages 371-373"},"PeriodicalIF":2.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148150150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of weight loss programs with physical exercise on the mood state of people with obesity: A systematic review","authors":"Ananda Quaresma Nascimento,&nbsp;Guilherme Torres Vilarino,&nbsp;Keyla Mara dos Santos,&nbsp;Darlan Laurício Matte,&nbsp;Alexandro Andrade","doi":"10.1016/j.orcp.2026.05.010","DOIUrl":"10.1016/j.orcp.2026.05.010","url":null,"abstract":"<div><h3>Introduction</h3><div>Individuals with obesity often face challenges related to mental health, including variations in mood state. However, evidence on how physical exercise within weight loss programs influences these outcomes remains limited.</div></div><div><h3>Objectives</h3><div>To examine the mood state of individuals with obesity enrolled in weight loss programs with physical exercise.</div></div><div><h3>Methods</h3><div>A Systematic review was conducted following the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. The searches were carried out in the databases Cochrane Library, Embase, PsycINFO, PubMed, Scopus, and Web of Science. Studies that addressed the population with obesity, applied physical exercise as the main intervention or as a complement to diet and/or behavioral intervention, and examined mood states before and after exercise were included.</div></div><div><h3>Results</h3><div>Seven studies were included, all using the Profile of Mood States scale. Most interventions combined physical exercise with dietary strategies, and some also included behavioral support. Improvements were more consistently observed in vigor and fatigue, whereas other mood domains showed variable results across studies. Interventions combining exercise with dietary and behavioral components tended to demonstrate more consistent improvements compared to exercise-only approaches. However, the evidence was limited by heterogeneity in intervention protocols and a high risk of bias, particularly in outcome measurement and randomization.</div></div><div><h3>Conclusion</h3><div>Weight loss programs incorporating physical exercise may be associated with improvements in certain mood states in individuals with obesity, particularly when combined with dietary and behavioral strategies. However, the evidence is heterogeneous and limited by methodological concerns, and findings should be interpreted with caution.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"20 4","pages":"Pages 268-275"},"PeriodicalIF":2.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148043100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Couple-level metabolic phenotypes and self-rated health in Korean adults","authors":"Kayoung Lee","doi":"10.1016/j.orcp.2026.04.009","DOIUrl":"10.1016/j.orcp.2026.04.009","url":null,"abstract":"<div><h3>Objective</h3><div>Self-rated health (SRH) is a widely used indicator of overall health and a robust predictor of morbidity and mortality. Although metabolic health and obesity are well-established determinants of SRH, most previous studies have examined these factors at the individual level. This study investigated how spousal metabolic phenotypes, defined by metabolic and weight status, are jointly associated with SRH among Korean adults.</div></div><div><h3>Methods</h3><div>We analyzed nationally representative data from 1817 heterosexual couples. Participants were classified into four phenotypes: metabolically healthy normal weight (MHNW), metabolically healthy obesity (MHO), metabolically unhealthy normal weight (MUNW), and metabolically unhealthy obesity (MUO). We applied actor–partner interdependence models (APIM) and couple-level analyses to assess associations with worse SRH, adjusting for sociodemographic factors, health behaviors, perceived stress, and comorbidities.</div></div><div><h3>Results</h3><div>Among husbands, the MUNW phenotype was significantly associated with worse SRH, with marginal partner effects were observed when wives were MUNW. Among wives, both MUNW and MUO were significant predictors of worse SRH, whereas partner effects were not significant. At the couple level, husbands had higher odds of worse SRH across all non-MHNW couple combinations, whereas wives had higher odds only in discordant couples in which the wife was non-MHNW and the husband was MHNW. Sensitivity analyses among older couples confirmed these findings.</div></div><div><h3>Conclusions</h3><div>These findings highlight gender-specific actor and partner effects and suggest that couple-level metabolic profiles may shape SRH, underscoring the importance of considering spousal metabolic status in its assessment.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"20 3","pages":"Pages 203-209"},"PeriodicalIF":2.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147818198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The weight of a hug: Abdominal obesity as a barrier to health and human connection","authors":"Jannatul Ferdous","doi":"10.1016/j.orcp.2026.04.003","DOIUrl":"10.1016/j.orcp.2026.04.003","url":null,"abstract":"<div><div>A hug is a simple act of human connection, yet for many individuals with abdominal obesity, it can be physically challenging and emotionally uncomfortable. This paper examines how abdominal obesity affects both health and social interactions, using hugging as an illustrative example. In collectivist cultures such as Bangladesh, physical touch reinforces trust and family bonds. Obesity-related limitations can reduce closeness; promote avoidance and lower self-confidence, often compounded by social stigma. Abdominal obesity is also associated with increased risks of cardiovascular disease, diabetes, and premature mortality. Its prevalence is driven by sedentary lifestyles, processed food consumption, and environmental factors, further exacerbated during the COVID-19 pandemic. Addressing abdominal obesity requires holistic strategies, including improved nutrition, regular physical activity, stress management, and community support, to restore comfort, rebuild confidence, and strengthen personal relationships and community cohesion.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"20 3","pages":"Pages 165-167"},"PeriodicalIF":2.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-esteem, depression and anxiety after surgery for obesity: A longitudinal pre/post study","authors":"Pierre Pournin,&nbsp;Magali Berthon,&nbsp;Vincent Kapps","doi":"10.1016/j.orcp.2026.04.002","DOIUrl":"10.1016/j.orcp.2026.04.002","url":null,"abstract":"<div><h3>Background</h3><div>People with obesity can experience psychosocial disorders, such as anxiety, depression and low self-esteem. Surgery for obesity may alleviate these factors, but the strength of this association is not clear.</div></div><div><h3>Methods</h3><div>In this retrospective longitudinal single center study, we assess changes in anxiety, depression (Hospital Anxiety and Depression Scale, HADS) and self-esteem (Rosenberg scale) six months before, and one year after, bariatric surgery. We use correlation analysis to investigate whether reduction in psychosocial suffering is associated with the amount of weight lost (percentage total body mass index, BMI kg/m²).</div></div><div><h3>Results</h3><div>105 patients were included, 85.7% female, with a mean age at surgery of 41.3 years (SD 10.4), mean weight of 112.5 kg (SD 16.2) and mean BMI of 41.2 (4.7) kg/m². Overall, 57 (54.3%) patients had sleeve surgery and 48 (45.7%) had a gastric bypass. Pre-operative weight reduced by a mean 36.0 (10.3) kilograms (P &lt; 0.0001). Baseline proportions of anxiety, depression and low self-esteem were high and improved one year after surgery (Low self-esteem: 46.7% [95%CI 37.4–56.2] to 18.1% [95%CI 11.9–26.5]; anxiety: 45.7% [95%CI 36.5–55.2] to 33.3% [95%CI 25.0–42.8]; and depression: 36.2% [95%CI 27.6–45.7] to 5.7% [95%CI 2.6–11.9]). Improvements in depression (<em>P</em> &lt; 0.05) and self-esteem (<em>P</em> &lt; 0.01) were greater for women. Average percentage total weight loss following surgery was 32.2% (SD 8.5) but there was no correlation with post-surgery anxiety, self-esteem or depression scores.</div></div><div><h3>Conclusions</h3><div>Self-esteem and depression improve markedly after bariatric surgery. Anxiety rates decline, but a high rate of people still experience clinical anxiety after surgery. Psychosocial gains after bariatric surgery may be greater for women who are in general younger and have higher baseline psychosocial burdens.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"20 3","pages":"Pages 210-215"},"PeriodicalIF":2.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147717483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of obesity: The role of sociodemographic factors, health behaviors, and quality of life in Spanish workers","authors":"María Dolores Marzoa Jansana ,&nbsp;Pedro Juan Tárraga López ,&nbsp;Juan José Guarro Miquel ,&nbsp;Ángel Arturo López-González ,&nbsp;Pere Riutord Sbert ,&nbsp;Carla Busquets-Cortés ,&nbsp;José Ignacio Ramírez-Manent","doi":"10.1016/j.orcp.2026.04.005","DOIUrl":"10.1016/j.orcp.2026.04.005","url":null,"abstract":"<div><h3>Background</h3><div>Obesity remains a major global health challenge with profound clinical, psychosocial, and economic consequences. Although body mass index (BMI) is widely used, alternative adiposity indices such as waist-to-height ratio (WtHR), Clínica Universidad de Navarra–Body Adiposity Estimator (CUN-BAE), and the Metabolic Score for Visceral Fat (METS-VF) may offer superior insights into central adiposity and cardiometabolic risk. Furthermore, the relationship between obesity and health-related quality of life (HRQoL) remains insufficiently explored in occupational settings, where lifestyle, socioeconomic, and psychosocial factors converge.</div></div><div><h3>Methods</h3><div>We conducted a cross-sectional study of 100,014 Spanish workers (18–69 years) who underwent standardized occupational health assessments between 2021 and 2023. Anthropometric and biochemical data were collected to calculate BMI, WtHR, CUN-BAE, and METS-VF. Sociodemographic characteristics, lifestyle habits (smoking, physical activity, and Mediterranean diet adherence), and HRQoL (12-Item Short Form Health Survey, SF-12) were also recorded. Logistic regression models were used to evaluate associations between obesity indices and sociodemographic, behavioral, and HRQoL variables, adjusting for potential confounders.</div></div><div><h3>Results</h3><div>Obesity prevalence varied markedly depending on the index employed, ranging from 17.2% with BMI to over 30% with CUN-BAE and METS-VF. Across all measures, older age, male sex, lower social class, smoking, physical inactivity, and poor adherence to the Mediterranean diet were significantly associated with higher odds of obesity. Importantly, workers with lower SF-12 physical and mental component scores consistently showed greater obesity risk, even after adjustment. These findings confirm the bidirectional interplay between excess adiposity and diminished quality of life.</div></div><div><h3>Conclusions</h3><div>In this large occupational cohort, obesity was strongly associated with adverse sociodemographic profiles, unhealthy lifestyles, and impaired HRQoL. Our results highlight the limitations of BMI alone and underscore the value of alternative adiposity indices in public health surveillance. Integrating HRQoL assessment into obesity prevention and workplace health programs may enhance early detection, risk stratification, and the design of holistic interventions targeting both physical and psychosocial well-being.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"20 3","pages":"Pages 185-193"},"PeriodicalIF":2.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147932225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is there a relationship between culinary skills and overweight/ obesity across life stages? A systematic review","authors":"Rafaela Nogueira Gomes de Morais ,&nbsp;Guilherme José Silva Ribeiro ,&nbsp;Juliana Farias de Novaes ,&nbsp;Daniela Mayumi Usuda Prado Rocha ,&nbsp;Ana Claudia Pelissari Kravchychyn ,&nbsp;Helen Hermana Miranda Hermsdorff","doi":"10.1016/j.orcp.2026.04.004","DOIUrl":"10.1016/j.orcp.2026.04.004","url":null,"abstract":"<div><h3>Introduction</h3><div>Obesity is a public health problem that affects millions of people worldwide, but its relationship with culinary skills has not yet been elucidated. This systematic review investigated the relationship between culinary skills and the prevalence of overweight and obesity among adolescents, adults, and older adults. We hypothesize that low cooking skills are associated with a higher prevalence of overweight and obesity across different life stages.</div></div><div><h3>Methods</h3><div>We searched the PubMed, Embase, and Web of Science databases from July to August 2024. The risk of bias assessment was performed using the Joanna Briggs Institute (JBI) tools.</div></div><div><h3>Results</h3><div>Five studies (three cross-sectional and two cohort) were included, totaling 53,557 subjects from Brazil, Italy, Canada, Japan, and France. The studies used body mass index or waist circumference to assess overweight and obesity. Culinary skills were evaluated using various non-standardized questionnaires covering knowledge, culinary techniques, cooking frequency, and ingredients used. One cohort study reported a negative association between culinary skills and overweight/obesity in adults. Conversely, two cross-sectional and cohort studies identified a positive association among adolescents and adults.</div></div><div><h3>Conclusions</h3><div>The relationship between culinary skills and overweight/obesity remains inconclusive across the studies. We encourage future research to understand this relationship across different life stages better and to validate appropriate tools for evaluating culinary skills.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"20 3","pages":"Pages 168-175"},"PeriodicalIF":2.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep, mental health, and body weight change in adults with obesity","authors":"Jeffrey J. VanWormer ,&nbsp;Galen Hoft ,&nbsp;Daniel L. Kurz ,&nbsp;Lauren Hand ,&nbsp;Catherine F. Siengsukon ,&nbsp;Christie A. Befort","doi":"10.1016/j.orcp.2026.05.004","DOIUrl":"10.1016/j.orcp.2026.05.004","url":null,"abstract":"<div><h3>Background/Objectives</h3><div>Sleep quality and affective disorders have independent associations with weight change, but how mental health and sleep interact to impact weight loss is unknown. The purpose of this study was to examine associations between baseline affective disorders, changes in sleep quality, and their impact on weight loss over 24 months among adults in a weight loss trial.</div></div><div><h3>Methods</h3><div>A secondary (cohort) analysis was conducted using data from the RE-POWER trial. Participants (n = 1298) were categorized by their affective disorder status at baseline and their 6-month changes in sleep quality (large improvement, moderate improvement, stable, or declined). Weight loss over 24 months was modeled as a continuous variable and as ≥ 5% weight loss threshold.</div></div><div><h3>Results</h3><div>In the model examining the ≥ 5% weight loss, there was a significant interaction (p = 0.035) between affective disorders, sleep quality change, and time. Among participants with an affective disorder, 54% of those with stable sleep and 60% of those with improved sleep achieved ≥ 5% weight loss, whereas just 31% of participants who experienced sleep decline achieved ≥ 5% weight loss by 6 months. By 24 months, the proportion of participants who lost ≥ 5% of their baseline body weight was more similar across groups. Exposure interactions were not significant in the continuous model of weight loss.</div></div><div><h3>Conclusions</h3><div>Baseline mental health and sleep quality decline can interact to inhibit successful weight loss, at least in the short term. Future weight management interventions should consider monitoring both affective disorders and sleep quality as potential markers for needing additional intervention support.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"20 3","pages":"Pages 216-221"},"PeriodicalIF":2.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147974207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}