Obesity research & clinical practice最新文献_第3页

Influence of waist circumference measurement site on the cardiometabolic risk factors in Korean adults

IF 2.5 4区医学

Obesity research & clinical practice Pub Date : 2025-01-01 DOI: 10.1016/j.orcp.2025.01.007

Yejin Kim , Jennifer L. Kuk , Kyung Hee Park , SoJung Lee

{"title":"Influence of waist circumference measurement site on the cardiometabolic risk factors in Korean adults","authors":"Yejin Kim , Jennifer L. Kuk , Kyung Hee Park , SoJung Lee","doi":"10.1016/j.orcp.2025.01.007","DOIUrl":"10.1016/j.orcp.2025.01.007","url":null,"abstract":"<div><h3>Background</h3><div>Waist circumference (WC) has been recognized as a simple anthropometric measure of abdominal obesity and associated health risk. We compared WC values at five measurement sites, and examined whether measurement sites influence the relationships between WC and cardiometabolic risk in Korean adults.</div></div><div><h3>Methods</h3><div>In this cross-sectional study, participants included 180 men and 176 women (age: 30–60 years, BMI: 18.5–30.0 kg/m<sup>2</sup>) who underwent a regular health examination between 2021 and 2022. WC was measured at the following sites; lowest rib, superior border of the iliac crest, midpoint between the lowest rib and the iliac crest, umbilicus, and narrowest waist. Fasting glucose and lipids, and resting blood pressure were measured after a 10-hour overnight fast. Cardiometabolic risk factors were defined using the modified National Cholesterol Education Program Adult Treatment Panel-III.</div></div><div><h3>Results</h3><div>All WC measures at five sites were highly correlated (<em>P</em> < 0.01) with each other in men (<em>r</em> = 0.933–0.995) and women (<em>r</em> = 0.893–0.990). Differences in absolute mean WC values existed in both men and women. The prevalence of abdominal obesity (men: 17.2 %-34.4 %, women: 5.7 %-40.9 %) and metabolic syndrome (men: 30.6 %-38.9 % women: 13.6 %-22.2 %) varied depending on the measurement site. All five WC sites were similarly associated (<em>P</em> < 0.05) with an increased odd ratio for elevated glucose, elevated triglycerides, low HDL cholesterol and cardiometabolic risk clustering in men, and elevated blood pressure and cardiometabolic risk clustering in women.</div></div><div><h3>Conclusion</h3><div>Although the differences in absolute WC values existed, the associations between WC at each site and cardiometabolic risk were similar in Korean adults.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 1","pages":"Pages 28-33"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143075054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is single anastomosis duodenoileal bypass (SADI) an effective option for conversional surgery following sleeve gastrectomy? A comprehensive review and revised scope of current literature

IF 2.5 4区医学

Obesity research & clinical practice Pub Date : 2025-01-01 DOI: 10.1016/j.orcp.2025.01.005

Ana Marta Pereira , Sofia S. Pereira , Mariana P. Monteiro , Marta Guimarães

{"title":"Is single anastomosis duodenoileal bypass (SADI) an effective option for conversional surgery following sleeve gastrectomy? A comprehensive review and revised scope of current literature","authors":"Ana Marta Pereira , Sofia S. Pereira , Mariana P. Monteiro , Marta Guimarães","doi":"10.1016/j.orcp.2025.01.005","DOIUrl":"10.1016/j.orcp.2025.01.005","url":null,"abstract":"<div><h3>Background</h3><div>Conversional surgery following sleeve gastrectomy (SG) is required in about 20 % of patients due to suboptimal outcomes. Single anastomosis duodenoileal bypass (SADI) has emerged as an option for such cases, though long-term outcomes remain unclear. This review analyzed available data on SADI as a conversional or second-stage procedure after SG.</div></div><div><h3>Methods</h3><div>A systematic search across PubMed, Web of Science, and Scopus included studies on adult patients who underwent SADI as a conversional or second-stage surgery following SG, with a minimum of 12 months’ follow-up up to July 2024.</div></div><div><h3>Results</h3><div>Nineteen studies involving 867 patients examined weight loss, comorbidity resolution, postoperative complications, and nutritional deficiencies. Results showed a total weight loss (TWL) of 24 % in the first year post-revision, with a trend toward weight stabilization or regain over two years. Maximum TWL (27 %) occurred at 24 months, decreasing to 24 % at 60 months. Average follow-up of 27 months showed remission rates for type 2 diabetes, hypertension, and dyslipidemia at 68 %, 53 %, and 37 %, respectively. Short-term morbidity within 30 days was 8 %, including a 5 % rate of anastomotic leaks or fistulas and a 5 % reoperation rate. Overall mortality was 2 %.</div></div><div><h3>Conclusion</h3><div>In conclusion, SADI shows promise as a safe and effective mid-term conversional surgery after SG with suboptimal results. However, further studies are needed to confirm its long-term safety and effectiveness.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 1","pages":"Pages 1-10"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating osteopontin as a biomarker of obesity related complications before and after metabolic and bariatric surgery: A systematic review and meta-analysis

IF 2.5 4区医学

Obesity research & clinical practice Pub Date : 2025-01-01 DOI: 10.1016/j.orcp.2025.01.010

Alessio Ardizzone , Rosalba Siracusa , Anna Paola Capra , Rosanna Di Paola , Emanuela Esposito , Salvatore Cuzzocrea , Ramona D’Amico , Daniela Impellizzeri

{"title":"Evaluating osteopontin as a biomarker of obesity related complications before and after metabolic and bariatric surgery: A systematic review and meta-analysis","authors":"Alessio Ardizzone , Rosalba Siracusa , Anna Paola Capra , Rosanna Di Paola , Emanuela Esposito , Salvatore Cuzzocrea , Ramona D’Amico , Daniela Impellizzeri","doi":"10.1016/j.orcp.2025.01.010","DOIUrl":"10.1016/j.orcp.2025.01.010","url":null,"abstract":"<div><h3>Background/Objectives</h3><div>Obesity is a major public health concern, significantly elevating the risk of developing comorbid conditions such as type 2 diabetes mellitus and cardio-vascular diseases, while also shortening life expectancy. Currently, metabolic and bariatric surgery (MBS) is one of the most effective long-term interventions for achieving substantial weight loss, alongside notable improvements in overall quality of life. However, evidence suggests that these procedures may negatively affect bone health, leading to an increased risk of fractures. This systematic review and meta-analysis aim to assess the role of Osteopontin (OPN) as a potential biomarker for predicting both persistent inflammation and bone deterioration following MBS.</div></div><div><h3>Methods</h3><div>A comprehensive search of scientific databases including PubMed (MEDLINE), Embase (OVID), and Web of Science, covering literature up to January 31, 2024, identified 6 studies that met the inclusion criteria for the systematic review. For the meta-analysis, data from 5 studies measuring circulating OPN levels pre- and post-surgery were pooled.</div></div><div><h3>Results</h3><div>The combined analysis revealed a significant increase in OPN levels after MBS compared to baseline (OR: 24.56; 95 % CI: 13.30–35.81; p < 0.0001).</div></div><div><h3>Conclusions</h3><div>These findings suggest that OPN may serve as a valuable biomarker for monitoring inflammation and assessing the risk of bone-related complications in patients following MBS.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 1","pages":"Pages 19-27"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insulin resistance and vigorous physical activity mediates the relationship between waist circumference and metabolic syndrome in Korean children

IF 2.5 4区医学

Obesity research & clinical practice Pub Date : 2025-01-01 DOI: 10.1016/j.orcp.2025.02.005

Seamon Kang, Mungu Song, Hyunsik Kang

{"title":"Insulin resistance and vigorous physical activity mediates the relationship between waist circumference and metabolic syndrome in Korean children","authors":"Seamon Kang, Mungu Song, Hyunsik Kang","doi":"10.1016/j.orcp.2025.02.005","DOIUrl":"10.1016/j.orcp.2025.02.005","url":null,"abstract":"<div><h3>Background</h3><div>Little is known about how physical activity (PA) and insulin resistance (IR) influence the impact of obesity on metabolic syndrome in pediatric populations.</div></div><div><h3>Objectives</h3><div>This cross-sectional observational study aimed to investigate the mediating effects of PA and IR on the relationship between waist circumference (WC) and continuous metabolic syndrome (cMetS) risk scores in children.</div></div><div><h3>Methods</h3><div>A total of 1008 children aged 7–12 years (535 girls and 473 boys) were recruited from our local elementary schools. PA, body mass index (BMI), WC, and percent body fat were measured. cMetS risk scores were calculated by summing the standardized residuals for mean arterial pressure, triglycerides, fasting blood glucose, and high-density lipoprotein cholesterol.</div></div><div><h3>Results</h3><div>Mediation analysis showed a significant indirect effect of WC on cMetS scores through insulin (β= 0.270, 95 % confidence interval [CI = 0.234–0.306) and vigorous PA (β= 0.007, 95 % CI = 0.001–0.015). The direct effect of WC on cMet scores in the presence of the two mediators was significant (β= 0.193, 95 % CI = 0.040–0.066).</div></div><div><h3>Conclusion</h3><div>Our study findings suggest that while WC is the primary determinant of cMetS scores, fasting insulin and vigorous PA partially mediate the association between the two parameters in this study population.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 1","pages":"Pages 43-47"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143433438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bariatric surgeons’ views on barriers and enablers to bariatric surgery in Australia and New Zealand: A qualitative content analysis 减肥外科医生对澳大利亚和新西兰减肥手术的障碍和促进因素的看法：定性内容分析。

IF 2.5 4区医学

Obesity research & clinical practice Pub Date : 2024-11-01 DOI: 10.1016/j.orcp.2024.12.002

Mia Majstorovic , Anna Chur-Hansen , Anne L.J. Burke , Jane M. Andrews

{"title":"Bariatric surgeons’ views on barriers and enablers to bariatric surgery in Australia and New Zealand: A qualitative content analysis","authors":"Mia Majstorovic , Anna Chur-Hansen , Anne L.J. Burke , Jane M. Andrews","doi":"10.1016/j.orcp.2024.12.002","DOIUrl":"10.1016/j.orcp.2024.12.002","url":null,"abstract":"<div><h3>Problem and Aims</h3><div>Bariatric surgery can be an effective treatment for severe obesity, yet publicly-funded access is often limited. Bariatric surgeons contribute to decisions regarding consumer (non)progression to bariatric surgery. Still, little is known about their views on barriers and enablers to bariatric surgery in the Australian and New Zealand context. The current study addresses this knowledge gap.</div></div><div><h3>Methods</h3><div>A qualitative design was utilised. Sixteen bariatric surgeons and registrars from Australia and New Zealand were interviewed about their views on barriers and enablers to bariatric surgery. The data were analysed using qualitative content analysis.</div></div><div><h3>Results</h3><div>Five content categories were derived from the analysis: 1. patient-related factors; 2. healthcare experiences and clinician-related factors; 3. societal beliefs and attitudes towards obesity, bariatric surgery and bariatric surgeons; 4. economic, governmental and institutional factors; and 5. bariatric surgery in the context of other treatments. A perceived lack of focus on obesity and publicly-funded bariatric surgery was apparent throughout the data in the form of descriptions of stigma, clinicians’ disillusionment, patients not being guided and supported, and inadequate regulation and organisation of the field. The role of patients in determining their surgical progression was emphasised.</div></div><div><h3>Conclusions</h3><div>Participants discussed numerous barriers but fewer facilitators to bariatric surgery in Australia and New Zealand. Some of their opinions merit exploration with other bariatric multi-disciplinary team members and patients to understand further how the pre-operative process might be enhanced to support patients’ needs and improve equity.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 6","pages":"Pages 443-449"},"PeriodicalIF":2.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142821767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High percentage of immune Th1 and Tc1 cells infiltrating visceral adipose tissue in people with obesity

IF 2.5 4区医学

Obesity research & clinical practice Pub Date : 2024-11-01 DOI: 10.1016/j.orcp.2024.12.006

Pedro Barbosa , Aryane Pinho , André Lázaro , Diogo Paula , José C. Campos , José G. Tralhão , Maria J. Pereira , Artur Paiva , Paula Laranjeira , Eugenia Carvalho

{"title":"High percentage of immune Th1 and Tc1 cells infiltrating visceral adipose tissue in people with obesity","authors":"Pedro Barbosa , Aryane Pinho , André Lázaro , Diogo Paula , José C. Campos , José G. Tralhão , Maria J. Pereira , Artur Paiva , Paula Laranjeira , Eugenia Carvalho","doi":"10.1016/j.orcp.2024.12.006","DOIUrl":"10.1016/j.orcp.2024.12.006","url":null,"abstract":"<div><div>Subcutaneous (SAT) and visceral (VAT) adipose tissue dysfunction during the obesity onset can lead to increased expression of inflammatory molecules, and consequently to immune cell infiltration. The aim was to deeply characterize the T cells, those infiltrating SAT and VAT, compared to peripheral blood (PB), in individuals undergoing bariatric surgery. Forty-two adult individuals were recruited, SAT and VAT samples were collected. T cell characterization was performed by flow cytometry. Results show that T cells infiltrating VAT from people with obesity display higher polarization towards Th1, Tc1 and T1-like CD4<sup>+</sup>CD8<sup>+</sup> T cells, compared to SAT. These cells also display higher percentage of activated cells, and a higher percentage of PD-1-expressing cells. Furthermore, the percentage of Th1/17 and Tc1/17 cells was increased 7–18 months post-surgery. In summary, the phenotype of T cells and their expression of PD-1 within SAT and VAT appear different, especially compared to PB.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 6","pages":"Pages 426-435"},"PeriodicalIF":2.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating genetic variants in early-onset obesity through exome sequencing: A retrospective cohort study 通过外显子组测序调查早发性肥胖的遗传变异：一项回顾性队列研究。

IF 2.5 4区医学

Obesity research & clinical practice Pub Date : 2024-11-01 DOI: 10.1016/j.orcp.2024.12.001

Deyun Liu, Yuxiang Liu, Chen yu Lu, Qian Wang, Yingying Bao, Yue Yu, Qiang Wang, Wu Peng

{"title":"Investigating genetic variants in early-onset obesity through exome sequencing: A retrospective cohort study","authors":"Deyun Liu, Yuxiang Liu, Chen yu Lu, Qian Wang, Yingying Bao, Yue Yu, Qiang Wang, Wu Peng","doi":"10.1016/j.orcp.2024.12.001","DOIUrl":"10.1016/j.orcp.2024.12.001","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to examine clinical data and analyze exome sequencing (ES) findings in children diagnosed with early-onset obesity.</div></div><div><h3>Methods</h3><div>We screened children presenting with severe (body mass index-standard deviation score >3) and early-onset (<7 years) obesity using ES. Participants were categorized into either the \"no variant identified\" group or the \"variant identified\" group, facilitating the exploration of correlations between clinical-demographic characteristics and genetic mutations linked to early-onset obesity. The functional implications of identified variants were assessed through in silico analyses.</div></div><div><h3>Results</h3><div>Of the patients, 32 (35.5 %) possessed one or more mutations in pathways associated with obesity, all of which were heterozygous and patients with more than two obesity-associated variants were more obese. This cohort included 29 novel mutations distinct to our study population, 7 previously reported pathogenic variants, two instances of uniparental disomy, and one mitochondrial hotspot mutation. Variants in the SH2B1 gene emerged as a prevalent genetic determinant of obesity within our group, accounting for 16.6 % of cases. Statistical evaluations showed no significant differences in demographic attributes between the two groups.</div></div><div><h3>Conclusion</h3><div>Exome sequencing proves to be an instrumental approach for uncovering new variants and broadening the spectrum of mutations in early-onset obesity among children. Concurrently, further functional studies, both in vitro and in vivo, are crucial to elucidate the contributions of these variants to obesity's pathogenesis.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 6","pages":"Pages 417-425"},"PeriodicalIF":2.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sustained effects after a multidisciplinary lifestyle modification program for children with excess weight and children affected with obesity 多学科生活方式改变项目对超重和肥胖儿童的持续影响。

IF 2.5 4区医学

Obesity research & clinical practice Pub Date : 2024-11-01 DOI: 10.1016/j.orcp.2025.01.001

Tung-En Chien , Pei-Shan Chen , Kai-Chi Chang , Chien-Ting Hsu , Hsi-Wen Huang , Shu-Mei Tsai , Yen-Tsz Chen , Chih-Hsuan Chang , Hui-Ru Yang , Yi-Ching Tung , Huey-Ling Chen

{"title":"Sustained effects after a multidisciplinary lifestyle modification program for children with excess weight and children affected with obesity","authors":"Tung-En Chien , Pei-Shan Chen , Kai-Chi Chang , Chien-Ting Hsu , Hsi-Wen Huang , Shu-Mei Tsai , Yen-Tsz Chen , Chih-Hsuan Chang , Hui-Ru Yang , Yi-Ching Tung , Huey-Ling Chen","doi":"10.1016/j.orcp.2025.01.001","DOIUrl":"10.1016/j.orcp.2025.01.001","url":null,"abstract":"<div><h3>Background</h3><div>Lifestyle modification (LM) is the mainstay in the management of obese children. This study aimed to investigate the long-term effects of a pediatric cohort participating in a hospital-based LM program.</div></div><div><h3>Methods</h3><div>Overweight/obese children and adolescents who visited a multidisciplinary LM program “The Health and Vitality Clinic” were included. Data on weight and height were collected at 6, 12, and 18 months following the initial visit. The changes in body mass index (BMI) and BMI z-score were analyzed.</div></div><div><h3>Results</h3><div>A total of 120 participants aged 5–18 years who visited the clinic were included. Sixty-one subjects who completed > 1 months (up to a maximum of 5 months) of the LM program constituted the LM group, while those who visited the clinic once were characterized as hospital-control (HC) group. There was a significant reduction in BMI at 6 and 12 months in the LM group, and at 6 months in the HC group, with a greater reduction observed in the LM group at 6 and 12 months (-1.05 ± 1.46 vs. −0.42 ± 1.21, <em>p</em> = 0.027; −0.87 ± 1.46 vs. −0.14 ± 1.43, <em>p</em> = 0.038, res<em>p</em>ectively). Both groups showed a downward trend in BMI z-score at 6, 12, and 18 months, with the LM group showing a greater reduction at the 6 months (-0.33 ± 0.28 vs. −0.22 ± 0.18, <em>p</em> = 0.019). BMI decline was more pronounced in adolescents than in children, showing variations in weight gains based on age.</div></div><div><h3>Conclusions</h3><div>The study demonstrated lasting effects in BMI and BMI z-score following the completion of the LM program.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 6","pages":"Pages 450-456"},"PeriodicalIF":2.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Obesity in the US: Exploring the paradox of increasing obesity rates alongside growing physical activity 美国的肥胖：探索肥胖率上升与体育锻炼增加的悖论。

IF 2.5 4区医学

Obesity research & clinical practice Pub Date : 2024-11-01 DOI: 10.1016/j.orcp.2024.12.004

Yoshiyasu Takefuji

引用次数: 0

Association of a healthy lifestyle index with anthropometric indices and obesity in Hong Kong Chinese women: Evidence from the MECH-HK cohort study 香港华裔女性的健康生活方式指数与人体测量指数和肥胖的关系：来自 MECH-HK 队列研究的证据。

IF 2.5 4区医学

Obesity research & clinical practice Pub Date : 2024-11-01 DOI: 10.1016/j.orcp.2025.01.003

Yunyang Deng , Tongyu Ma , Fei Wan Ngai , Harry Haoxiang Wang , Lin Yang , Qi Sun , Yao Jie Xie

{"title":"Association of a healthy lifestyle index with anthropometric indices and obesity in Hong Kong Chinese women: Evidence from the MECH-HK cohort study","authors":"Yunyang Deng , Tongyu Ma , Fei Wan Ngai , Harry Haoxiang Wang , Lin Yang , Qi Sun , Yao Jie Xie","doi":"10.1016/j.orcp.2025.01.003","DOIUrl":"10.1016/j.orcp.2025.01.003","url":null,"abstract":"<div><h3>Aim</h3><div>This cross-sectional study aimed to examine the associations of a healthy lifestyle index (HLI) with several anthropometric indices and obesity among Hong Kong Chinese women.</div></div><div><h3>Subjects/Methods</h3><div>A total of 3174 women (56.16 ± 8.43 years) were included. The HLI consisted of diet, physical activity, sedentary time, sleep duration, skipping breakfast, smoking, and alcohol. Each factor was scored as 0 (unhealthy) or 1 (healthy). The overall HLI was the sum of these points, ranging from 0 (the least healthy) to 7 (healthiest). Percent body fat (PBF), body fat mass (BFM), fat free mass (FFM), waist circumference (WC), waist-to-hip ratio (WHR), height, and weight were measured using the InBody 270 device.</div></div><div><h3>Results</h3><div>The number of women with 0–2, 3, 4, 5, 6–7-point HLI groups were 551, 759, 954, 645, and 265, respectively. As HLI increased, most anthropometric indices declined while FFM increased. The adjusted βs (95 % confidence intervals (95 % CIs)) for PBF (%), BFM (kg), WC (cm), WHR, height (cm), weight (kg), BMI (kg/m^2), and FFM (kg) were −0.653 (-0.829, −0.476), −0.582 (-0.751, −0.414), −0.719 (-0.971, −0.467), −0.005 (-0.006, −0.004), −0.181 (-0.347, −0.015), −0.602 (-0.850, −0.355), −0.188 (-0.282, −0.095), and 0.339 (0.213, 0.465), respectively. Additionally, compared to the 0–2-point group, the odds ratios (95 % CIs) of the 6–7-point groups were 0.54 (0.38–0.75) for central obesity and 0.55 (0.37–0.82) for general obesity.</div></div><div><h3>Conclusions</h3><div>HLI was inversely associated with PBF, BFM, WC, WHR, height, weight, BMI, central obesity, and general obesity, but was positively associated with FFM.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 6","pages":"Pages 401-408"},"PeriodicalIF":2.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0