Obesity research & clinical practice最新文献

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The impact of paternal body mass index on semen parameters and assisted reproductive outcomes in couples undergoing IVF/ICSI-ET treatment. 父亲体重指数对接受IVF/ICSI-ET治疗的夫妇精液参数和辅助生殖结果的影响
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-08-30 DOI: 10.1016/j.orcp.2025.08.007
Jing Yi Han, Chen Yang, Bing Nan Ren, Pei Xin Li, Ran Shen, Wei Zheng, Ruo Wen Zu, Yi Xuan Yan, Yue Yang, Man Yu Hu, Yi Chun Guan
{"title":"The impact of paternal body mass index on semen parameters and assisted reproductive outcomes in couples undergoing IVF/ICSI-ET treatment.","authors":"Jing Yi Han, Chen Yang, Bing Nan Ren, Pei Xin Li, Ran Shen, Wei Zheng, Ruo Wen Zu, Yi Xuan Yan, Yue Yang, Man Yu Hu, Yi Chun Guan","doi":"10.1016/j.orcp.2025.08.007","DOIUrl":"https://doi.org/10.1016/j.orcp.2025.08.007","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the impact of paternal body mass index (BMI) on semen parameters and assisted reproductive outcomes in couples undergoing their first IVF/ICSI-ET cycle.</p><p><strong>Materials and methods: </strong>This retrospective study included 7618 couples undergoing IVF/ICSI-ET for maternal tubal/pelvic factors from 2017 to 2023. Paternal BMI was classified according to WHO criteria: normal weight (n = 3433), overweight (n = 3248), and obese (n = 937). Semen quality, embryological outcomes (utilizable/high-quality embryos, blastocysts), and ART outcomes (pregnancy, singleton live birth) were compared. ANOVA, chi-square tests, and multivariate regression were used; subgroup analyses were conducted for IVF and ICSI-ET.</p><p><strong>Results: </strong>Normal sperm morphology was higher in the normal weight group (5.32 ± 4.92 %) vs. overweight (4.85 ± 3.53 %) and obese (4.79 ± 4.93 %) (P < 0.001). Utilizable embryo rate was higher in the normal weight group (84.22 ± 19.29 %) than in the overweight group (82.98 ± 20.20 %) (P = 0.018). The utilizable blastocyst rate was also higher vs. obese group (29.60 ± 22.61 % vs. 26.93 ± 21.87 %; P = 0.004). Clinical pregnancy rates were 59.2 %, 56.6 %, and 55.5 % in the normal, overweight, and obese groups, respectively (P = 0.037). ICSI subgroup showed limited ART differences except higher birthweight in the obese group (P = 0.003).</p><p><strong>Conclusions: </strong>Men with normal BMI demonstrated better sperm morphology, embryo utilization, and pregnancy rates. These findings underscore the importance of assessing paternal BMI in ART and support integrating paternal weight management into preconception care.</p>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of abdominal obesity in the Portuguese population assessed by different anthropometric indices. 用不同的人体测量指数评估葡萄牙人群中腹部肥胖的患病率。
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-08-26 DOI: 10.1016/j.orcp.2025.08.006
Maria Santos, Mafalda Sousa-Uva, Sónia Namorado, Teresa Gonçalves, Carlos Matias Dias, Vânia Gaio
{"title":"Prevalence of abdominal obesity in the Portuguese population assessed by different anthropometric indices.","authors":"Maria Santos, Mafalda Sousa-Uva, Sónia Namorado, Teresa Gonçalves, Carlos Matias Dias, Vânia Gaio","doi":"10.1016/j.orcp.2025.08.006","DOIUrl":"https://doi.org/10.1016/j.orcp.2025.08.006","url":null,"abstract":"<p><strong>Introduction: </strong>Cardiovascular diseases are the leading cause of death globally. The association between abdominal obesity and cardiovascular risk is well established. This study aimed to estimate and characterize the prevalence of abdominal obesity in the Portuguese population aged 25-74 years in 2015, using waist circumference, waist to- hip ratio, waist-to-height ratio, and a body shape index.</p><p><strong>Methods: </strong>Data from the First National Health Examination Survey, a cross-sectional study, was used. Participants aged between 25 and 74 years, not pregnant, and with available data on anthropometric measurements (weight, height, waist circumference, and hip circumference) were included. Individuals undergoing cancer treatment were excluded from the study.</p><p><strong>Results: </strong>Among 4812 participants the prevalence of abdominal obesity according to each considered anthropometric measure was 40.3 % (95 % CI: 38.0-42.5), 43.6 % (95 % CI: 40.1-47.0), 65.2 % (95 % CI: 62.8-67.5) and 75.5 % (95 % CI: 74.1-76.9) when considering waist circumference, a body shape index, waist-to-hip ratio and waist-to-height ratio, respectively. The most affected individuals had 60-74 years, with no formal education or only primary education and engaged in low-skilled occupations (e.g., farmers, industrial workers, and construction workers). These findings remained consistent, regardless of the index under consideration.</p><p><strong>Conclusion: </strong>The prevalence of abdominal obesity ranged from 40.3 % for waist circumference to 75.5 % for waist-to-height ratio. Nonetheless, irrespective of the index employed, the prevalence was elevated. Older individuals, with lower education levels, and those engaged in less skilled occupations were most affected. Early identification of abdominal obesity in Primary Healthcare is essential.</p>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between carotenoids and weight-adjusted waist index a cross-sectional study based on the national health and nutrition examination survey 2017–2018 类胡萝卜素与体重调整腰围指数的相关性——基于2017-2018年全国健康与营养检查调查的横断面研究
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-07-01 DOI: 10.1016/j.orcp.2025.06.006
Huirong Shi , Peichao Zhang , Chai Yang , Tao Lv
{"title":"Association between carotenoids and weight-adjusted waist index a cross-sectional study based on the national health and nutrition examination survey 2017–2018","authors":"Huirong Shi ,&nbsp;Peichao Zhang ,&nbsp;Chai Yang ,&nbsp;Tao Lv","doi":"10.1016/j.orcp.2025.06.006","DOIUrl":"10.1016/j.orcp.2025.06.006","url":null,"abstract":"<div><h3>Purpose</h3><div><span><span>The weight-adjusted waist index (WWI) is a novel method for assessing abdominal obesity, offering greater accuracy than do </span>body mass index and waist circumference in determining lean and </span>fat mass<span><span>. Carotenoids, known for their antioxidant properties, can effectively neutralize </span>free radicals. We aimed to examine the relationship between serum carotenoid levels and WWI.</span></div></div><div><h3>Methods</h3><div>Data used in this study were obtained from the National Health and Nutrition Examination Survey between 2017 and 2018. Serum carotenoid levels were assessed via high-performance liquid chromatography. A multiple linear regression model was used to examine the correlation between serum carotenoid levels and WWI. Furthermore, potential nonlinear associations were identified using smooth curve fitting.</div></div><div><h3>Principal results</h3><div>In this population-based survey, 3829 participants were included. Multivariate linear regression analysis revealed that the highest serum carotenoid tertile was significantly associated with lower WWI values. The effect sizes (β) and 95 % confidence intervals were −0.31 (-0.37, −0.24), −0.37 (-0.43, −0.31), −0.24 (-0.31, −0.18), and −0.28 (-0.34, −0.21) for α-carotene, β-carotene, β-cryptoxanthin, and lutein/zeaxanthin, respectively. Smoothed curve fitting showed that β-carotene, β-cryptoxanthin, and lutein/zeaxanthin exhibited a nonlinear relationship with WWI.</div></div><div><h3>Major conclusions</h3><div>Several serum carotenoids were inversely associated with WWI in the general population of the United States, suggesting a potential protective role against abdominal obesity. However, further large-scale prospective studies are required to confirm these findings.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 4","pages":"Pages 283-288"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Get Involved Reach Top Health (GIRTH): A community-based, peer-led group lifestyle modification program for men – A quasi-randomised trial 参与达到最佳健康(GIRTH):一项以社区为基础,以同伴为主导的男性生活方式改变计划-一项准随机试验
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-07-01 DOI: 10.1016/j.orcp.2025.08.001
Margaret McGee , Vanessa Glennon , Kate Warren , Manny Noakes , Deborah Turnbull , Camille E. Short , Andrew D. Vincent , Gary A. Wittert
{"title":"Get Involved Reach Top Health (GIRTH): A community-based, peer-led group lifestyle modification program for men – A quasi-randomised trial","authors":"Margaret McGee ,&nbsp;Vanessa Glennon ,&nbsp;Kate Warren ,&nbsp;Manny Noakes ,&nbsp;Deborah Turnbull ,&nbsp;Camille E. Short ,&nbsp;Andrew D. Vincent ,&nbsp;Gary A. Wittert","doi":"10.1016/j.orcp.2025.08.001","DOIUrl":"10.1016/j.orcp.2025.08.001","url":null,"abstract":"<div><div>Men are underrepresented in community-based lifestyle modification programs (LMP). A quasi-randomised trial was undertaken to assess the efficacy of GIRTH, a peer-led, group-based LMP for men, in reducing cardiometabolic risk factors. One-hundred-seventy-eight men (mean age 58 yrs, waist circumference 110 cm) in 11 groups, were allocated 1:3 to either a control group receiving healthy lifestyle information only (n = 45) or a GIRTH group involving 12, weekly, face-to-face sessions focused on health literacy, goal setting, problem solving and self-monitoring (n = 133). The primary outcome was waist circumference (WC) change over 12-weeks. Secondary outcomes included changes in body mass index (BMI), blood pressure, grip strength, lipid profile and glucose, diet, physical activity, and diet, exercise, coping, and sleep self-efficacy scores. The retention was 68 % and 88 % for the control and GIRTH groups respectively. WC decreased in both groups (p &lt; 0.001), but the decrease was greater in the GIRTH group (intention-to-treat: −4.2 cm, −5.1 to −3.3 vs −1.9 cm, −3.1 to −0.7; p = 0.002; as-treated: −5.3 cm, −6.1 to −4.4 vs −3.0 cm, −4.6 to −1; p = 0.009). Men in both groups had improvements in weight, BMI, blood pressure, in coping, sleep and regulate eating self-efficacy scores, and physical activity (p &lt; 0.05). Men in the GIRTH group also had improvements in high density lipoprotein (HDL), triglyceride (TC)/HDL ratio, and exercise self-efficacy score (p &lt; 0.05). Reduction in WC correlated with changes in weight, BMI, systolic blood pressure, lipids, and increased fruit and vegetable consumption (p &lt; 0.05). The GIRTH program was more effective than information alone in reducing WC and cardiometabolic disease risk factors in men.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 4","pages":"Pages 316-325"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144895296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perceived self-efficacy and body mass index to identify older adults with and without fall history 感知自我效能和身体质量指数来识别有和没有跌倒史的老年人。
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-07-01 DOI: 10.1016/j.orcp.2025.06.003
Roberta C.D. Bohrer , Alessandra S. Bianchi , Emily Balcetis , Benny W.C. Wong , André L.F. Rodacki
{"title":"Perceived self-efficacy and body mass index to identify older adults with and without fall history","authors":"Roberta C.D. Bohrer ,&nbsp;Alessandra S. Bianchi ,&nbsp;Emily Balcetis ,&nbsp;Benny W.C. Wong ,&nbsp;André L.F. Rodacki","doi":"10.1016/j.orcp.2025.06.003","DOIUrl":"10.1016/j.orcp.2025.06.003","url":null,"abstract":"<div><h3>Objective</h3><div>The study aimed to analyze the relationship between a combined set of variables of several domains to identify older adults with and without a fall history. It was also aimed to identify the contribution of the variables included in the model.</div></div><div><h3>Methods</h3><div>This cross-sectional study was conducted with 191 older adults who performed the Timed-up-and-go Test (TUG), an imaginary TUG (iTUG), and were assessed for physical characteristics. The difference between the actual and imagined performances was calculated to represent perceived self-efficacy (TUG<sub>diff</sub><span><span>). A decision tree model was applied to indicate the relevant variables to identify fallers and non-fallers, and a </span>logistic regression was also used to determine the contribution of such variables.</span></div></div><div><h3>Results</h3><div><span>The decision tree identified body mass index (BMI) and TUG</span><sub>diff</sub> as related to fall risk, with an accuracy of 71.4 %. Individuals with a BMI &lt; 26.4 kg.m<sup>−2</sup> were identified as non-fallers, while those with a BMI &gt; 26.4 kg.m<sup>−2</sup> and a TUG<sub>diff</sub> lower than 3.89 s were also identified as non-fallers. The sensitivity of 0.91 and specificity of 0.26 showed good model accuracy in identifying non-fallers. The regression included BMI and TUG<sub>diff</sub> as the main explanatory factors, while age, sex, cognition, TUG, and iTUG were not included as covariates because they did not reach the relative importance threshold of 15% in the decision tree analysis.</div></div><div><h3>Conclusion</h3><div>Older adults with decreased BMI were less prone to experience a fall. Older adults with increased BMI may experience a protective benefit of more accurate self-efficacy and become less prone to falls.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 4","pages":"Pages 310-315"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144497562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
De novo anorexia nervosa post-bariatric surgery 减肥手术后神经性厌食症的新生。
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-07-01 DOI: 10.1016/j.orcp.2025.06.005
Romy Chu , Jacob Desman , Hannah Lynch , Isabela Hill , Georgina Devine , Timothy Rice
{"title":"De novo anorexia nervosa post-bariatric surgery","authors":"Romy Chu ,&nbsp;Jacob Desman ,&nbsp;Hannah Lynch ,&nbsp;Isabela Hill ,&nbsp;Georgina Devine ,&nbsp;Timothy Rice","doi":"10.1016/j.orcp.2025.06.005","DOIUrl":"10.1016/j.orcp.2025.06.005","url":null,"abstract":"<div><div>Metabolic and bariatric surgery is generally known to decrease rates of eating disorders post-procedure. In the relatively uncommon event that an eating disorder develops de novo or recurs after bariatric surgery, most cases are associated with suboptimal weight loss or further weight gain. This case report presents the history of a 56-year-old woman without a prior eating disorder diagnosis who developed anorexia nervosa restricting type after bariatric surgery, leading to psychiatric hospitalization. Implications for surgical decision-making in tandem with psychiatric screening pre-surgically, follow-up, and management are reviewed and recommendations made.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 4","pages":"Pages 364-366"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Healthcare costs according to obesity and physical activity: 8-year longitudinal study among patients assisted by the Brazilian National Healthcare System 根据肥胖和身体活动的医疗费用:巴西国家医疗保健系统协助患者的8年纵向研究。
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-07-01 DOI: 10.1016/j.orcp.2025.08.005
Luana Carolina de Morais , Monique Yndawe Castanho Araujo , Kelly Akemi Kikuti Koyama , Ítalo Ribeiro Lemes , Romulo Araújo Fernandes , Bruna Camilo Turi-Lynch , Henrique Luiz Monteiro , Jamile Sanches Codogno
{"title":"Healthcare costs according to obesity and physical activity: 8-year longitudinal study among patients assisted by the Brazilian National Healthcare System","authors":"Luana Carolina de Morais ,&nbsp;Monique Yndawe Castanho Araujo ,&nbsp;Kelly Akemi Kikuti Koyama ,&nbsp;Ítalo Ribeiro Lemes ,&nbsp;Romulo Araújo Fernandes ,&nbsp;Bruna Camilo Turi-Lynch ,&nbsp;Henrique Luiz Monteiro ,&nbsp;Jamile Sanches Codogno","doi":"10.1016/j.orcp.2025.08.005","DOIUrl":"10.1016/j.orcp.2025.08.005","url":null,"abstract":"<div><h3>Introduction</h3><div>Obesity is a risk factor for the development of many chronic diseases, and, consequently, it is associated with an increase in the use of health services. On the other hand, practicing physical activity reduces healthcare costs. However, the long-term roles of physical activity and obesity in healthcare costs are not well explored in the literature.</div></div><div><h3>Objective</h3><div>This study aimed to investigate the physical activity (PA) and obesity trajectory in relation to health costs, in participants treated by primary care, over a period of eight years.</div></div><div><h3>Methods</h3><div>The sample included 291 participants, aged ≥ 50 years, evaluated between 2010 and 2018. Weight and height were used to calculate the body mass index (BMI), and PA was evaluated by a questionnaire. Healthcare costs were extracted from medical records. The General Structural Equation Model (GSEM) was used to analyze the trajectory of the variables in the eight-year follow-up.</div></div><div><h3>Results</h3><div>In 2010, the median healthcare cost was US$51.61, an increase of 54 % compared to 2018. BMI and PA decreased by around 2 % and 22.6 %, respectively. At baseline, BMI affected the trajectory of health costs, increasing costs by US$ 1.55 (p = 0.024).</div></div><div><h3>Conclusion</h3><div>In conclusion, in eight years, participants presented decreases in BMI and PA and increases in health costs. BMI, but not PA, affected the increase in healthcare costs at baseline.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 4","pages":"Pages 346-351"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Training ChatGPT for surgical decisions: Bariatric surgery analysis using algorithms and evidence 训练ChatGPT用于手术决策:使用算法和证据进行减肥手术分析。
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-07-01 DOI: 10.1016/j.orcp.2025.08.002
Sergi Sanchez-Cordero , Ruth Lopez-Gonzalez , Helena Fernandez , Jordi Pujol-Gebellí
{"title":"Training ChatGPT for surgical decisions: Bariatric surgery analysis using algorithms and evidence","authors":"Sergi Sanchez-Cordero ,&nbsp;Ruth Lopez-Gonzalez ,&nbsp;Helena Fernandez ,&nbsp;Jordi Pujol-Gebellí","doi":"10.1016/j.orcp.2025.08.002","DOIUrl":"10.1016/j.orcp.2025.08.002","url":null,"abstract":"<div><h3>Background</h3><div>Selecting the most appropriate bariatric surgery (BS) technique is a complex, individualized process. Artificial intelligence (AI) tools like ChatGPT may assist, but their clinical utility is unclear. This study evaluates whether ChatGPT’s recommendations for BS improve after exposure to scientific literature and how they align with real-world clinical decisions.</div></div><div><h3>Methods</h3><div>A retrospective single-center study included 283 patients who underwent primary BS between 2023 and 2025. No exclusion criteria were applied. Clinical variables (age, sex, BMI, comorbidities, and preoperative data) were collected. ChatGPT was asked to recommend the most suitable BS technique for each patient profile, first without context and then after being exposed to 412 open-access scientific articles. Recommendations were compared with actual clinical decisions using percentage agreement and Cohen’s Kappa.</div></div><div><h3>Results</h3><div>Initially, ChatGPT favored sleeve gastrectomy (SG, 56.8 %), followed by Roux-en-Y gastric bypass (RYGB, 26.8 %) and one-anastomosis gastric bypass (OAGB, 16.4 %); SADI-S was never suggested. Concordance with clinical practice was 20.0 % (Kappa = 0.003; p = 0.96). After training, SG recommendations decreased (35.7 %), RYGB increased (30.3 %), SADI-S emerged (17.1 %), and dual options appeared in 4 %. Concordance improved modestly to 25.8 % (Kappa = 0.068; p = 0.29), with a significant shift in global distribution (p &lt; 0.00001).</div></div><div><h3>Conclusions</h3><div>ChatGPT adapts its recommendations after contextual training, but concordance with clinical judgment remains low. While potentially useful as an educational tool, ChatGPT is not yet reliable for autonomous surgical decision-making.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 4","pages":"Pages 352-355"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations between body mass index and filled prescription medications among US military service members 美国军人身体质量指数与处方药之间的关系
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-07-01 DOI: 10.1016/j.orcp.2025.08.003
Joseph J. Knapik , Daniel W. Trone , Ryan A. Steelman , Harris R. Lieberman
{"title":"Associations between body mass index and filled prescription medications among US military service members","authors":"Joseph J. Knapik ,&nbsp;Daniel W. Trone ,&nbsp;Ryan A. Steelman ,&nbsp;Harris R. Lieberman","doi":"10.1016/j.orcp.2025.08.003","DOIUrl":"10.1016/j.orcp.2025.08.003","url":null,"abstract":"<div><div>This cross-sectional investigation examined associations between body mass index (BMI) and filled prescription medications (FPMs) among military service members (SMs). A stratified random sample of active duty SMs was obtained from military workforce records. Participants (n = 26,117) completed a questionnaire on demographics and lifestyle factors and their FPMs were obtained from the military Pharmacy Data Transaction Service. Medications were classified by their American Hospital Formulary System Pharmacologic-Therapeutic Classification System (PTCS) codes. FPMs across PTCS codes were compared across three BMI levels: normal weight (&lt;25.0 kg/m<sup>2</sup>), overweight (25.0–29.9 kg/m<sup>2</sup>), and obese (≥30 kg/m<sup>2</sup>). SMs who were overweight and obese had 1.21 (95 %confidence interval [95 %CI]=1.14–1.29) and 1.60 (95 %CI=1.47–1.75) times higher odds of a FPM than normal weight SMs, respectively. Compared to normal weight SMs, SMs who were overweight had higher prevalence of FPMs in 14 of 20 PTCS codes and SMs who were obese in 15 of 20 PTCS codes, after adjustment for demographic and lifestyle factors. In most PTCS codes there was a dose-response such that as BMI level increased so did the prevalence of FPMs. In this young, physically active group of SMs, prevalence of many types of FPMs increased as BMI increased in a dose-response pattern.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 4","pages":"Pages 339-345"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144862378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between waist-to-height ratio and headache symptoms in U.S. youth: A nationwide cross-sectional study 美国青少年腰高比与头痛症状之间的关系:一项全国性的横断面研究。
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-07-01 DOI: 10.1016/j.orcp.2025.07.002
Xinyu Lei , Liu Wang , Ruilin He, Zongbin Jiang
{"title":"Association between waist-to-height ratio and headache symptoms in U.S. youth: A nationwide cross-sectional study","authors":"Xinyu Lei ,&nbsp;Liu Wang ,&nbsp;Ruilin He,&nbsp;Zongbin Jiang","doi":"10.1016/j.orcp.2025.07.002","DOIUrl":"10.1016/j.orcp.2025.07.002","url":null,"abstract":"<div><h3>Objective</h3><div>To examine the association between waist-to-height ratio (WHtR), a marker of central adiposity, and the odds of frequent or severe headaches, including migraines, in U.S. children and adolescents.</div></div><div><h3>Methods</h3><div>We analyzed 8915 participants aged 8–19 years in the 1999–2004 National Health and Nutrition Examination Survey (NHANES). WHtR was calculated as waist circumference divided by height and scaled by 10 to reflect the effect of a 0.1-unit increase. We applied survey-weighted logistic regression models to estimate associations between WHtR and self-reported headache status, adjusting for demographic, metabolic, and behavioral covariates. Additional interaction and sensitivity analyses were conducted to assess effect modification and robustness.</div></div><div><h3>Results</h3><div>Each 0.1-unit increase in WHtR was associated with a 26 % higher odds of reporting headaches (OR = 1.26, 95 % CI: 1.15, 1.38; <em>p</em> &lt; 0.001). Compared to the lowest quartile (Q1), participants in the highest quartile (Q4) had 34 % greater odds (OR = 1.34, 95 % CI: 1.06, 1.70). Restricted cubic spline models demonstrated a linear dose–response association (<em>p</em> for nonlinearity = 0.96). The association remained robust across multiple sensitivity analyses.</div></div><div><h3>Conclusion</h3><div>WHtR was linearly associated with the odds of frequent or severe headaches in U.S. youth. Although the cross-sectional design limits causal inference, WHtR may serve as a simple and developmentally stable marker for identifying obesity-related neurological symptoms, warranting further longitudinal investigation.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 4","pages":"Pages 303-309"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144789559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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