Obesity research & clinical practice最新文献

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Obesity affects the association between Serum Klotho and age-related hearing loss: A cross-sectional study 肥胖影响血清Klotho与年龄相关性听力损失之间的关系:一项横断面研究。
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-05-01 DOI: 10.1016/j.orcp.2025.04.006
Jingchao Yan, Ling Li, Qing Ye , Taomin Huang
{"title":"Obesity affects the association between Serum Klotho and age-related hearing loss: A cross-sectional study","authors":"Jingchao Yan,&nbsp;Ling Li,&nbsp;Qing Ye ,&nbsp;Taomin Huang","doi":"10.1016/j.orcp.2025.04.006","DOIUrl":"10.1016/j.orcp.2025.04.006","url":null,"abstract":"<div><h3>Objective</h3><div>The influence of obesity on the interplay between Klotho and age-related hearing loss (ARHL) requires further exploration. This study investigates the impact of obesity on the correlation between Serum Klotho levels and ARHL prevalence in a large cohort.</div></div><div><h3>Methods</h3><div>The present study analyzed data from the National Health and Nutrition Examination Survey (NHANES) involving 3355 participants. Participants were stratified based on body mass index (BMI) into non-obese (BMI &lt; 30 kg/m²) and obese (BMI ≥ 30 kg/m²) groups. We then assessed the interaction between serum Klotho levels and the risk of ARHL using multivariable logistic regression. Restricted cubic splines were employed to evaluate the dose-response relationship between serum Klotho and ARHL in both non-obese and obese groups.</div></div><div><h3>Results</h3><div>In non-obese participants, serum Klotho levels were significantly associated with ARHL in both univariate (OR = 0.84, 95 % CI 0.77–0.93, p &lt; 0.001) and multivariable analyses (OR = 0.88, 95 % CI 0.79–0.99, p = 0.034). A restricted cubic spline model confirmed a linear relationship between serum Klotho and ARHL in this group (p for non-linearity = 0.969). Conversely, no significant association was found in obese participants. These findings underscore a persistent association between serum Klotho and ARHL in non-obese individuals after adjusting for confounding factors.</div></div><div><h3>Conclusion</h3><div>Obesity appears to modulate the association between serum Klotho levels and age-related hearing loss, offering potential insights for improving prevention and management strategies for hearing impairment.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 3","pages":"Pages 247-253"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144038143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of body mass index on recurrent stroke in stroke survivors: An updated systematic review and meta-analysis 身体质量指数对卒中幸存者复发性卒中的影响:一项最新的系统综述和荟萃分析。
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-05-01 DOI: 10.1016/j.orcp.2025.05.003
Sheng Lun Wei, Kuan Lin Chiu
{"title":"Impact of body mass index on recurrent stroke in stroke survivors: An updated systematic review and meta-analysis","authors":"Sheng Lun Wei,&nbsp;Kuan Lin Chiu","doi":"10.1016/j.orcp.2025.05.003","DOIUrl":"10.1016/j.orcp.2025.05.003","url":null,"abstract":"<div><h3>Background</h3><div>This updated systematic review and meta-analysis aimed to re-evaluate the potential impact of body mass index (BMI) on the risk of recurrent stroke among stroke survivors.</div></div><div><h3>Methods</h3><div>We systematically searched PubMed, EMBASE, and Cochrane CENTRAL databases for studies published up to January 20, 2025. Eligible studies included randomized controlled trials, cohort studies, or case-control studies enrolling adult stroke or transient ischemic attack (TIA) survivors, with at least one year of follow-up, and reporting stroke recurrence by BMI categories. Studies were required to define stroke using clinical diagnosis or the International Classification of Disease (ICD) codes, and to categorize BMI using the World Health Organization (WHO) or Asia-Pacific classifications. The primary outcome was recurrent stroke risk between individuals with and without obesity, assessed using risk ratios (RRs). Secondary outcomes evaluated recurrent stroke risk across WHO BMI categories using adjusted hazard ratios (HRs). (PROSPERO: CRD42024580168)</div></div><div><h3>Results</h3><div>Fourteen studies (136,581 subjects) were included in the qualitative review (systematic review). Two using Asia-Pacific criteria were excluded, leaving 12 studies using WHO-classified BMI for quantitative synthesis (meta-analysis). Meta-analysis showed no significant difference in stroke recurrence between individuals with and without obesity (RR = 0.89, 95 % CI: 0.71–1.13). Meta-analysis of adjusted HRs showed no significant difference in stroke recurrence risk for individuals with underweight or overweight compared to those with normal weight. However, in the subgroup with ≥ 3 years follow-up, overweight was significantly associated with lower recurrent stroke risk (HR = 0.91). Also, individuals with obesity had a significantly lower stroke recurrence risk than normal weight individuals (HR = 0.85), particularly among those aged ≥ 65 years (HR = 0.82).</div></div><div><h3>Conclusions</h3><div>Overweight and obesity may be associated with a lower risk of stroke recurrence, particularly in older adults and during long-term follow-up (≥ 3 years). These findings suggest a potential obesity paradox in stroke survivors, warranting further investigations.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 3","pages":"Pages 202-213"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144013034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new homozygous pathogenic LEPR variant causing severe, early onset obesity in a Senegalese child 一种新的纯合子致病性LEPR变异导致塞内加尔儿童严重的早发性肥胖。
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-05-01 DOI: 10.1016/j.orcp.2025.04.007
Virginie Deswarte , Louis Lebreton , Pascal Barat , Jérôme Delplanque , Amélie Bonnefond , Marine Delagrange
{"title":"A new homozygous pathogenic LEPR variant causing severe, early onset obesity in a Senegalese child","authors":"Virginie Deswarte ,&nbsp;Louis Lebreton ,&nbsp;Pascal Barat ,&nbsp;Jérôme Delplanque ,&nbsp;Amélie Bonnefond ,&nbsp;Marine Delagrange","doi":"10.1016/j.orcp.2025.04.007","DOIUrl":"10.1016/j.orcp.2025.04.007","url":null,"abstract":"<div><div>We report the case of a three-year-old Senegalese child presenting with severe obesity and hyperphagia since birth. Despite normal birth parameters and non-consanguineous parents with average BMI, the child exhibited rapid weight gain, surpassing obesity thresholds before the age of one. Genetic analysis revealed a novel homozygous variant in the <em>LEPR</em> gene (c.3190 G&gt;T; p.(Glu1064Ter)). Functional assays demonstrated impaired leptin receptor signaling due to this truncating mutation. This case highlights the importance of considering monogenic causes in early-onset obesity. Identifying specific mutations enables the proposal of targeted therapies and the adaptation of clinical management.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 3","pages":"Pages 279-282"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reframing food addiction in childhood obesity: Cultural relevance and digital innovation needed 重新定义儿童肥胖中的食物成瘾:需要文化相关性和数字创新。
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-05-01 DOI: 10.1016/j.orcp.2025.05.005
Riza Amalia, Ronal Surya Aditya, Salmiati, Herul Wahyudin
{"title":"Reframing food addiction in childhood obesity: Cultural relevance and digital innovation needed","authors":"Riza Amalia,&nbsp;Ronal Surya Aditya,&nbsp;Salmiati,&nbsp;Herul Wahyudin","doi":"10.1016/j.orcp.2025.05.005","DOIUrl":"10.1016/j.orcp.2025.05.005","url":null,"abstract":"<div><div>This letter responds to the article by An et al. on the link between food addiction and emotional and behavioral problems in children with obesity. We highlight two key points. First, most research on food addiction comes from Western countries, yet childhood obesity is rising quickly in low- and middle-income countries (LMICs), especially in Southeast Asia. Cultural differences in food habits, family roles, and emotional expression may affect how food addiction appears and should be studied. Second, tools like the Yale Food Addiction Scale for Children (YFAS-C) must be carefully adapted and validated for different cultures—not just translated. We also suggest using digital tools, like apps and games, to support treatment, but these should be designed ethically and tested properly. We call for global research partnerships and culturally sensitive approaches to better understand and address food addiction in children worldwide</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 3","pages":"Pages 273-274"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the prevalence of hyperglycemia and the link to physical fitness in young Danish women with overweight – A cross-sectional study 一项横断面研究:探讨丹麦年轻超重女性高血糖的患病率及其与身体健康的关系。
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-05-01 DOI: 10.1016/j.orcp.2025.04.009
Line Barner Dalgaard , Line Thams , Jon Skovgaard Jensen , Astrid Ank Jørgensen , Lene Ring Madsen , Andreas Breenfeldt Andersen , Kasper Degn Gejl , Hanne Christine Bertram , Mette Hansen
{"title":"Exploring the prevalence of hyperglycemia and the link to physical fitness in young Danish women with overweight – A cross-sectional study","authors":"Line Barner Dalgaard ,&nbsp;Line Thams ,&nbsp;Jon Skovgaard Jensen ,&nbsp;Astrid Ank Jørgensen ,&nbsp;Lene Ring Madsen ,&nbsp;Andreas Breenfeldt Andersen ,&nbsp;Kasper Degn Gejl ,&nbsp;Hanne Christine Bertram ,&nbsp;Mette Hansen","doi":"10.1016/j.orcp.2025.04.009","DOIUrl":"10.1016/j.orcp.2025.04.009","url":null,"abstract":"<div><h3>Background</h3><div>Diagnosis of type 2 diabetes (T2D) at 20 years of age is associated with a reduction in life expectancy of 17.9 years. With an increasing prevalence of overweight among young people, we aimed to assess the prevalence of T2D and intermediate hyperglycaemia among young Danish women with overweight or obesity, who had not been previously diagnosed with T2D. Furthermore, we aimed to examine associations between markers of hyperglycaemia (glucose tolerance, fasting glucose, insulin, and HOMA-IR), body composition, physical fitness, and other lifestyle factors.</div></div><div><h3>Methods</h3><div>In this multicentre, cross-sectional study, we included 111 women aged 18–30 years with BMI&gt; 25 kg/m<sup>2</sup> who engaged in little or no regular physical activity. Participants underwent an oral glucose tolerance test and fasting blood samples were obtained and analysed for fasting glucose, insulin, and lipids. Other outcomes included measurements of anthropometry and body composition (DXA), physical activity level (PAL), physical fitness (Aastrand’s bike test), hand grip strength, and countermovement jump. Dietary intake was estimated through 4-day dietary records, and calcium intake was estimated through food frequency questionnaires.</div></div><div><h3>Results</h3><div>Among women (24 ± 3 years) with a BMI of 30.9 ± 4.8 kg·m-2, 19.8 % were classified with intermediate hyperglycaemia and 2.7 % with T2D, despite no previous diabetes diagnosis. Markers of hyperglycaemia were inversely associated with PAL and physical fitness and positively associated with BMI and fat mass.</div></div><div><h3>Conclusion</h3><div>In a cohort of young women with overweight or obesity, not previously diagnosed with T2D, every fifth exhibited intermediate hyperglycaemia, which was linked to low physical fitness and high BMI.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 3","pages":"Pages 232-238"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cross-sectional and longitudinal associations of DXA-measured body composition with lung function in middle-aged Australians: The Busselton Healthy Ageing Study 澳大利亚中年人dxa测量的身体成分与肺功能的横断面和纵向关联:Busselton健康老龄化研究
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-05-01 DOI: 10.1016/j.orcp.2025.05.004
Kun Zhu , Michael Hunter , John P. Walsh , Jennie Hui , Matthew Knuiman , Alan James , Siobhain Mulrennan
{"title":"Cross-sectional and longitudinal associations of DXA-measured body composition with lung function in middle-aged Australians: The Busselton Healthy Ageing Study","authors":"Kun Zhu ,&nbsp;Michael Hunter ,&nbsp;John P. Walsh ,&nbsp;Jennie Hui ,&nbsp;Matthew Knuiman ,&nbsp;Alan James ,&nbsp;Siobhain Mulrennan","doi":"10.1016/j.orcp.2025.05.004","DOIUrl":"10.1016/j.orcp.2025.05.004","url":null,"abstract":"<div><h3>Background</h3><div>Limited data are available on the association of body composition and lung function in middle-aged adults. We investigated the cross-sectional and longitudinal associations in participants of the Busselton Healthy Ageing Study.</div></div><div><h3>Methods</h3><div>At baseline (n = 4857, aged 46–70 years) and 6-year follow-up (n = 3436), body mass index (BMI), fat and lean mass index (FMI and LMI) and abdominal visceral adipose tissue (VAT) using dual-energy x-ray absorptiometry (DXA), forced expiratory volume in one second (FEV1 % predicted) and forced vital capacity (FVC % predicted) were assessed. Relationships were examined using linear regression, adjusted for age, lifestyle factors and comorbidities.</div></div><div><h3>Results</h3><div>At baseline, the reduction in FEV1 % and FVC% for each additional 1 kg/m<sup>2</sup> of FMI was twice greater than that of BMI (men: 1.5–1.9 vs 0.4–0.7; women: 1.0–1.2 vs 0.3–0.5); in contrast each additional 1 kg/m<sup>2</sup> of LMI was associated with 1.3–1.6 units increment in FEV1 % and FVC%. In the longitudinal analysis, ∆FEV1 % and ∆FVC% per 1 kg/m<sup>2</sup> increment in ∆FMI were −2.2 and −2.3 in men and −1.0 and −1.1 in women, in comparison with −1.8 and −1.9 in men and −0.8 and −0.9 in women for ∆BMI. The range of change in LMI over time was narrow, and ∆LMI had little impact on ∆FEV1 % and ∆FVC%. Higher baseline VAT and greater increase over time were associated with lower lung function, but not totally independent of FMI.</div></div><div><h3>Conclusion</h3><div>In middle-aged adults, increased fat mass is a driver for lung function deterioration, whereas higher baseline lean mass may have a protective effect.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 3","pages":"Pages 254-260"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144094476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ACTION Teens: Perceptions and attitudes towards obesity among adolescents living with obesity, caregivers and healthcare professionals in South Korea 青少年行动:韩国肥胖青少年、护理人员和医疗保健专业人员对肥胖的看法和态度。
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-05-01 DOI: 10.1016/j.orcp.2025.04.004
Yong Hee Hong , Hyun Wook Chae , Hae Sang Lee , Eungu Kang , Moon Bae Ahn , Da Hi Kang , Min Jee Kim , Young-Jun Rhie
{"title":"ACTION Teens: Perceptions and attitudes towards obesity among adolescents living with obesity, caregivers and healthcare professionals in South Korea","authors":"Yong Hee Hong ,&nbsp;Hyun Wook Chae ,&nbsp;Hae Sang Lee ,&nbsp;Eungu Kang ,&nbsp;Moon Bae Ahn ,&nbsp;Da Hi Kang ,&nbsp;Min Jee Kim ,&nbsp;Young-Jun Rhie","doi":"10.1016/j.orcp.2025.04.004","DOIUrl":"10.1016/j.orcp.2025.04.004","url":null,"abstract":"<div><h3>Background</h3><div>In South Korea, the prevalence of adolescents living with obesity (ALwO) is rising.</div></div><div><h3>Objectives</h3><div>To evaluate perceptions, attitudes, behaviors, and obstacles to effective obesity care among ALwO, caregivers, and healthcare professionals (HCPs) in South Korea.</div></div><div><h3>Methods</h3><div>ACTION Teens (NCT05013359) was a multinational, cross-sectional survey conducted in 2021. Data from South Korean participants are reported (476 ALwO, 523 caregivers, 200 HCPs).</div></div><div><h3>Results</h3><div>Most ALwO/caregivers acknowledged that they/their ALwO had overweight, obesity or severe obesity (95 %/88 %, respectively) and were concerned about weight impacting their/their ALwO’s future health (94 %/91 %, respectively). The predominant information source on weight management for ALwO/caregivers was YouTube (62 %/35 %, respectively).</div><div>Most HCPs (87 %) indicated obesity had a strong impact on overall health; fewer ALwO (70 %) and caregivers (62 %) provided the same responses. ALwO recognized the societal challenges associated with overweight/obesity (versus healthy weight), with 50 %, 37 %, and 36 % reporting that overweight/obesity makes it harder to get a job, make friends, and perform well at school, respectively (compared with 41 %, 28 %, and 26 % of caregivers). A higher proportion of ALwO (80 %) than caregivers (45 %) thought weight loss was completely the ALwO's responsibility. While 82 % of ALwO reported they had made a recent weight-loss attempt, only 60 % of caregivers reported that their ALwO had made a recent weight-loss attempt; HCPs thought that, on average, 35 % of their ALwO patients had attempted to lose weight.</div></div><div><h3>Conclusions</h3><div>Disparities in respondents’ perceptions and attitudes toward obesity underscore the need for enhanced communication and increased understanding of obesity to improve healthcare strategies for South Korean ALwO.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 3","pages":"Pages 261-269"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of bariatric surgery on serum C5a levels: A prospective study 减肥手术对血清C5a水平的影响:一项前瞻性研究
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-05-01 DOI: 10.1016/j.orcp.2025.04.005
Mariana D.S. Testa , Renato Nisihara , Alessandro F. Tonial , Paulo A. Nunes Nassif , Thelma Skare
{"title":"Impact of bariatric surgery on serum C5a levels: A prospective study","authors":"Mariana D.S. Testa ,&nbsp;Renato Nisihara ,&nbsp;Alessandro F. Tonial ,&nbsp;Paulo A. Nunes Nassif ,&nbsp;Thelma Skare","doi":"10.1016/j.orcp.2025.04.005","DOIUrl":"10.1016/j.orcp.2025.04.005","url":null,"abstract":"<div><div>C5a, a key complement pathway component, is produced in adipose tissue and promotes inflammation linked to atherosclerosis. It also influences lipid and glucose metabolism, suggesting a role in obesity-related dysfunction. This study measured by ELISA serum C5a levels in individuals with obesity before and after Roux-en-Y gastric bypass. Pre-surgery, the median C5a level was 12.0 ng/mL (IQR: 7.0–18.0); post-surgery, it dropped to 6.3 ng/mL (IQR: 4.4–8.9; p = 0.0002). However, no significant correlations were found between C5a changes and lipid or glycemic profiles.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 3","pages":"Pages 270-272"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144021179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Asia–Oceania consensus: Definitions and diagnostic criteria for sarcopenic obesity 亚洲-大洋洲共识:肌少性肥胖的定义和诊断标准。
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-05-01 DOI: 10.1016/j.orcp.2025.05.001
Tsung-Po Chen , Hsiang-Han Kao , Wataru Ogawa , Hidenoi Arai , Dicky Levenus Tahapary , Prasert Assantachai , Kwang-Wei Tham , Ding-Cheng Chan , Michele Mae-Ann Yuen , Geeta Appannah , Mia Fojas , Timothy Gill , Meng-Chih Lee , Banshi Saboo , Cheng-Chieh Lin , Kyoung-Kon Kim , Wen-Yuan Lin
{"title":"The Asia–Oceania consensus: Definitions and diagnostic criteria for sarcopenic obesity","authors":"Tsung-Po Chen ,&nbsp;Hsiang-Han Kao ,&nbsp;Wataru Ogawa ,&nbsp;Hidenoi Arai ,&nbsp;Dicky Levenus Tahapary ,&nbsp;Prasert Assantachai ,&nbsp;Kwang-Wei Tham ,&nbsp;Ding-Cheng Chan ,&nbsp;Michele Mae-Ann Yuen ,&nbsp;Geeta Appannah ,&nbsp;Mia Fojas ,&nbsp;Timothy Gill ,&nbsp;Meng-Chih Lee ,&nbsp;Banshi Saboo ,&nbsp;Cheng-Chieh Lin ,&nbsp;Kyoung-Kon Kim ,&nbsp;Wen-Yuan Lin","doi":"10.1016/j.orcp.2025.05.001","DOIUrl":"10.1016/j.orcp.2025.05.001","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of this study was to develop consensus definitions and diagnostic criteria for sarcopenic obesity tailored to Asia-Oceania populations, a condition characterized by reduced skeletal muscle mass and function with excess adipose tissue.</div></div><div><h3>Methods</h3><div>Experts from various fields formed a working group under the Asia–Oceania Association for the Study of Obesity (AOASO) and the International Association of Gerontology and Geriatrics Asia/Oceania Region (IAGG-AOR). The group convened four meetings, employing the Delphi technique to achieve consensus on diagnostic criteria and management strategies for sarcopenic obesity.</div></div><div><h3>Results</h3><div>The consensus defines sarcopenic obesity with a 3-step algorithm, including screening, diagnosis, and intervention. The screening criteria included BMI and waist circumference for obesity and calf circumference, the SARC-F, and the Finger Ring test for sarcopenia. The diagnostic criteria for sarcopenia include assessments of muscle mass (using dual-energy X-ray absorptiometry or bioelectrical impedance analysis), muscle strength (handgrip strength), and physical performance (gait speed, Short Physical Performance Battery, or the 5-Times Sit-to-Stand Test). Central obesity is the main concern for the diagnosis of obesity. The working group recommends a combination of dietary consultations, increased physical activity, resistance training, and the potential use of oral nutritional supplements and medications for managing sarcopenic obesity. The primary objective is to increase skeletal muscle mass and reduce adipose tissue mass.</div></div><div><h3>Conclusions</h3><div>The established criteria facilitate early recognition and management of sarcopenic obesity, highlighting the need for tailored interventions. Future research should focus on the long-term outcomes of these interventions and the development of pharmacological treatments.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 3","pages":"Pages 185-192"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144013307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of COVID-19 pandemic on weight loss in the digital Healthy Weight Coaching program COVID-19大流行对数字健康体重指导计划中减肥的影响。
IF 2.5 4区 医学
Obesity research & clinical practice Pub Date : 2025-05-01 DOI: 10.1016/j.orcp.2025.04.008
Aila J. Ahola, Mikko S. Venäläinen, Anu Joki, Laura-Unnukka Suojanen, Kirsi H. Pietiläinen
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