Nutricion hospitalaria最新文献

{"title":"Micronutrients adequacy according to six diet quality indices in the \"Seguimiento Universidad de Navarra\" cohort.","authors":"Itziar Zazpe, Susana Santiago, María Barbería-Latasa, Maira Bes-Rastrollo, Carmen de la Fuente-Arrillaga, Miguel Ángel Martínez González","doi":"10.20960/nh.05411","DOIUrl":"10.20960/nh.05411","url":null,"abstract":"<p><strong>Introduction: </strong>Objectives: diet quality indices (DQI) tend to relate positively to micronutrient intake. Our aim was to investigate the association between six DQIs and inadequate intake for 19 micronutrients in the SUN (\"Seguimiento Universidad de Navarra\") cohort. Methods: we assessed 16,768 participants (59.3 % women, 37.8 years for mean age). Diet quality was evaluated using Dietary Approaches to Stop Hypertension (DASH); Mediterranean Diet Adherence Screener (MEDAS); Alternate Healthy Eating Index (AHEI-2010); Food-Based Global Diet Quality Score (GDQS); Alternative Mediterranean Diet Score (aMED) and Mediterranean Diet Score (MDS). Logistic regression analyses were conducted to estimate the probability of failing to meet Estimate Average Requirement (EAR) for either ≥ 3 or ≥ 6 micronutrients. Results: overall, the lower and higher prevalence of inadequacy in fifth quintiles was for vitamins A, C, B1, B2, B3, B6, for Fe, P and Cr, and for vitamins E and D, respectively. In the multivariable adjusted model, the OR for failing to meet ≥ 3 DRI for the highest versus the lowest quintiles of DASH, MEDAS, AHEI-2010, GDQS, aMED and MDS were: 0.03 (95 % CI, 0.02 to 0.03), 0.06 (95 % CI, 0.05 to 0.07), 0.10 (95 % CI, 0.09 to 0.12), 0.05 (95 % CI, 0.04 to 0.06), 0.03 (95 % CI, 0.03 to 0.04), and 0.07 (95 % CI, 0.06 to 0.09), respectively. Conclusions: adherence to six DQIs showed inverse associations with micronutrient inadequacy. Food-based DQIs could be a useful prevention tool. GDQS and MEDAS do not require deriving nutrient intake data, particularly MEDAS, which is even easier and quicker to fill out.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":"319-332"},"PeriodicalIF":2.5,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NHANES data analysis of the cardiometabolic index in relation to lumbar spine bone mineral density.","authors":"Rui Zhu, Chao-Ren Deng, Shao-Ping Wu","doi":"10.20960/nh.05548","DOIUrl":"10.20960/nh.05548","url":null,"abstract":"<p><strong>Introduction: </strong>Objective: to investigate the correlation between cardiometabolic index (CMI) and lumbar spine bone mineral density (LSBMD) in U.S. adults. Methods: the study selected eligible participants from the National Health and Nutrition Examination Survey (NHANES) database from 2011 to 2018. After adjusting for age, gender, race/ethnicity, body mass index (BMI), liver function markers, kidney function markers, blood routine indicators, metabolic markers, and chronic disease status, a logistic regression model combined with a restricted cubic spline model, smooth curve fitting, and threshold effect analysis was used to examine the association between CMI and LSBMD. Subgroup analysis was performed to verify the robustness of the results. Result: among the 3,885 participants, for each unit increase in CMI, LSBMD decreased by 0.011 g/cm². Additionally, a turning point was identified at CMI = 0.797. When CMI was below 0.797, LSBMD decreased as CMI increased, showing a strong negative correlation (β = -0.077, 95 % CI: -0.097 to -0.058, p < 0.001). However, beyond this threshold, the relationship between CMI and LSBMD was no longer significant. Subgroup analysis revealed that the negative correlation between CMI and BMD was consistent across most subgroups (such as gender, BMI, hypertension, and high cholesterol), but instability was observed in subgroups such as individuals aged 51-59, Mexican Americans, non-Hispanic Blacks, and those with diabetes. Conclusion: there exists a non-linear inverse correlation with CMI and LSBMD, showing that CMI could be a potential contributing factor for decreased bone mineral density, with a more pronounced effect within a specific range.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":"333-340"},"PeriodicalIF":2.5,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating sarcopenia and nutritional status in outpatients with liver cirrhosis: concordance of diagnostic methods.","authors":"Marina Demas Rezende Gischewski, Fernanda Lívia Cavalcante Araujo, Aryana Isabelle De Almeida Neves Siqueira, Alina Joana da Silva Wallraf, João Araújo Barros Neto, Nassib Bezerra Bueno Nassib, Juliana Célia de Farias Santos, Fabiana Andréa Moura","doi":"10.20960/nh.05585","DOIUrl":"10.20960/nh.05585","url":null,"abstract":"<p><strong>Introduction: </strong>Introduction and objectives: malnutrition and sarcopenia are prevalent in individuals with cirrhosis, but their diagnosis remains challenging due to limited access to suitable methods across different levels of healthcare. This study aimed to identify the most effective method for diagnosing sarcopenia in outpatients with liver cirrhosis and to evaluate the concordance between subjective and objective diagnostic methods. Patients and methods: patients aged ≥ 18 years with a diagnosis of cirrhosis (regardless of etiology) under outpatient care were included. Exclusion criteria were: a) neoplasia, b) acute liver failure, c) pregnancy/lactation, d) HIV infection, e) special situations requiring liver transplantation, and f) history of organ failure. Nutritional and sarcopenia assessments used subjective methods, including the Royal Free Hospital-Nutritional Prioritizing Tool (RFH-NPT), SARC-F, SARC-Calf, and RFH-Global Assessment (RFH-GA); and objective methods, including anthropometry, handgrip strength (HGS), the sit-and-stand test (15s), and appendicular skeletal muscle mass index (ASMI) by Dual-Energy X-ray Absorptiometry (DXA). Concordance between ASMI and traditional methods was analyzed. Significance was set at p < 0.05. Results: a total of 45 patients were analyzed, with alcoholic liver disease being the most frequent etiology (44.4 %). The sit-and-stand test (15s) combined with muscle depletion by DXA diagnosed the most cases of sarcopenia (42.2 %). Moderate agreement was found between muscle depletion and isolated calf circumference (CC) (κ = 0.581; p < 0.001). Conclusions: our study suggests excluding SARC-F and SARC-CalF from sarcopenia screening in outpatients with cirrhosis. While ASMI remains the most reliable diagnostic method, CC may serve as a feasible alternative when DXA is unavailable.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":"292-301"},"PeriodicalIF":2.5,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrase strand transfer inhibitors, their impact in adipose tissue and weight gain in people living with HIV - A narrative review.","authors":"María Magdalena Valle-Hernández, Elba Reyes-Maldonado, José Antonio Mata Marín, Mireya Núñez Armendáriz, Juan Gaytán-Martínez, Ericka Nelly Pompa-Mera","doi":"10.20960/nh.05562","DOIUrl":"https://doi.org/10.20960/nh.05562","url":null,"abstract":"<p><p>Greater weight gain following initiation of antiretroviral therapy (ART) with integrase strand transfer inhibitors (INsTI) compared with that seen with other classes of antiretroviral drugs, is an increasingly recognized problem in people living with HIV (PLWH). The purpose of this narrative review is to highlight those clinical trials that have documented weight gain and associated factors among PLWH on INsTI-ART. This includes the underlying pathophysiological mechanisms, toxicity, impact on adipose tissue, and how this tissue becomes metabolically dysfunctional, contributing to the emergence of insulin resistance and other comorbidities in PLWH. Considering the impact of the modern obesogenic environment and that PLWH on INsTI-ART are living longer, a coordinated approach by infectious disease specialists and other physicians to address the metabolic complications affecting this population, is imperative. The use of new anti-obesity drugs is becoming part of co-medication to limit weight gain in this population.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Mental health and eating styles: a comparative analysis of account types and content on social media].","authors":"Nelson Hun Gamboa, Felipe González-Fernández, Víctor Sepúlveda Sanhueza","doi":"10.20960/nh.05620","DOIUrl":"https://doi.org/10.20960/nh.05620","url":null,"abstract":"<p><strong>Introduction: </strong>the use of social media platforms like Instagram and TikTok has grown exponentially. The types of accounts and content followed may negatively affect eating styles and mental health in young adults.</p><p><strong>Objectives: </strong>to compare restrictive and emotional eating styles, as well as stress and anxiety levels, based on the types of accounts and content followed on social media by adults aged 18 to 35 in Chile.</p><p><strong>Methods: </strong>a cross-sectional, comparative study was conducted with 549 participants aged 18 to 35, who completed self-report questionnaires to assess anxiety, stress, and eating styles. Content type was classified into two categories: A) recipes and B) weight loss and fitness recommendations. Accounts followed were grouped into three types: A) professional, B) mixed, and C) unknown origin.</p><p><strong>Results: </strong>female Instagram users showed higher levels of restrictive eating (M = 2.61, SD = 1.00) and emotional eating (M = 2.45, SD = 1.12), stress (M = 20.53, SD = 10.57), and anxiety (M = 15.77, SD = 11.32) compared to male users. Weight loss-oriented content was associated with significantly higher restrictive eating levels in women. Accounts managed by trained professionals were linked to lower stress and anxiety levels for both sexes.</p><p><strong>Conclusions: </strong>social media usage influences eating styles and mental health, especially among women. Following professional accounts was associated with lower levels across all indicators, highlighting the need to regulate social media content and ensure that health and nutrition information is communicated by qualified professionals.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Higher frequency of adding salt to foods increases the risk of low bone mineral density in individuals over 60 - A Mendelian randomization study.","authors":"Ying Li, Yuhan Wang, Lianying Guo, Ye Yu, Mengqi Jiang, Lili Deng, Qingyi Zhou, Lu Sun, Xu Feng, Zhuo Zhang","doi":"10.20960/nh.05492","DOIUrl":"https://doi.org/10.20960/nh.05492","url":null,"abstract":"<p><strong>Background: </strong>Adding salt to foods is associated with an increased osteoporosis risk, but the causality of this relationship remains unknown.</p><p><strong>Methods: </strong>in this study, we conducted a two-sample Mendelian randomization (MR) study to investigate the potential causal effect of adding salt to foods on bone mineral density (BMD). Utilizing data from the UK Biobank to estimate adding salt to foods based on self-reported consumption and genetic association data for BMD from the Genetic Factors for Osteoporosis (GEFOS) consortium, we examined various BMD sites: forearm (distal 1/3 radius), lumbar spine (L1-4), femoral neck, total body BMD (TB-BMD), and age-specific TB-BMD (0-15, 15-30, 30-45, 45-60, and over 60 years). The primary analysis used the inverse variance weighted method, supplemented by sensitivity analyses employing multiple MR methods, MR-PRESSO, and leave-one-out approach. Pleiotropy and heterogeneity were assessed using MR-Egger intercept, funnel plots, Cochran's Q, and Rucker's Q.</p><p><strong>Results: </strong>we found a suggestive association between higher frequency of adding salt to foods and decreased TB-BMD in Europeans over 60 (OR = 0.84, 95 % CI = 0.721-0.979, p = 0.026). This association remained robust across different methods and sensitivity analyses, showing no apparent heterogeneity or pleiotropy. However, no causal effect was detected on BMD in other age groups or skeletal sites.</p><p><strong>Conclusion: </strong>this MR study suggests a higher frequency of adding salt to foods significantly increases low BMD risk in individuals over 60, underscoring the importance of reducing salt consumption in this demographic for osteoporosis prevention.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A prospective study of regular milk drinking and the risk of all-cause and cause-specific mortality in U.S. adults: findings from the NHANES 2003-2008.","authors":"Fei Zhao, Liyan Zhu, Ye Lu, Hongwei Xia, Shengchao Zhang, Ping Zhang","doi":"10.20960/nh.05623","DOIUrl":"https://doi.org/10.20960/nh.05623","url":null,"abstract":"<p><strong>Background: </strong>scholars have studied the influences of milk consumption on health. This prospective cohort study evaluated the association between regular milk consumption (RMD) and mortality, including all-cause, cardiovascular disease (CVD), and cancer-specific mortality, in Americans who were aged 20 years and older.</p><p><strong>Methods: </strong>it was attempted to analyze data from the 2003 to 2008 National Health and Nutrition Examination Survey (NHANES), including 8,653 participants with an average follow-up of 160.59 months (standard deviation = 0.96). Regular milk consumption (RMD) was defined as drinking milk at least five times per week. Cox proportional hazards regression models were thereafter utilized for analysis.</p><p><strong>Results: </strong>a significant association was noticeable particularly between RMD and higher rates of all-cause mortality (hazard ratio (HR) = 1.27; 95 % confidence interval (CI): 1.03-1.56; p = 0.03) and cancer mortality (HR = 1.53; 95 % CI: 1.01-2.32; p = 0.04), rather than with CVD mortality (HR = 1.03; 95 % CI: 0.73-1.44; p = 0.84). The association between RMD and all-cause mortality was notably observed across various subgroups in sensitivity and subgroup analyses.</p><p><strong>Conclusions: </strong>these outcomes unveiled the importance of exercising caution with milk consumption, which could be emphasized in public health recommendations.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between low dairy consumption and determinants of health in Latin American university students: a multicenter study.","authors":"Diego Gajardo, Georgina Gómez, Valeria Carpio-Arias, Leslie Landaeta-Díaz, Israel Ríos, Solange Parra, Jacqueline Alejandra Araneda Flores, Gladys Ruth Morales Illanes, Eliana Meza, Beatriz Núñez, Gabriela Murillo, Karla Rosángel Cordón Arrivillaga, Edna Judith Nava González, Saby Marisol Mauricio Alza, Jhon Bejarano Rocancio, Brian M Cavagnari, Rodrigo Valenzuela, Samuel Durán Agüero","doi":"10.20960/nh.05513","DOIUrl":"https://doi.org/10.20960/nh.05513","url":null,"abstract":"<p><strong>Objective: </strong>to associate low dairy consumption with determinants of health and the Human Development Index (HDIs) in Latin American university students.</p><p><strong>Methods: </strong>a cross-sectional, multicenter, observational study in university students from eleven Latin American countries.</p><p><strong>Results: </strong>the study included 4880 subjects. In all, 66 % of the sample consumed at least one serving of dairy products per day. A higher percentage of dairy consumers was observed among participants who are in the highest quartile of quality of life as compared to those in the lowest quartile (p < 0.001). Dairy consumption was positively associated with the consumption of breakfast (OR, 1.58; 95 % CI, 1.36-1.85), healthy dinner (OR, 1.16; 95 % CI, 1.01-1.32), fruits (OR, 1.77; 95 % CI, 1.53-2.05), vegetables (OR, 1.19; 95 % CI, 1.02-1.39), fish (OR: 1.37; 95 % CI, 1.36-1.85), whole-grain foods (OR, 1.72; 95 % CI, 1.49-1.98), and the practice of physical activity (OR, 1.16; 95 % CI, 1.01-1.34), and was negatively associated with the consumption of fried food (non-consumption) (OR, 0.72; 95 % CI, 0.58-0.90), junk food (OR, 0.78; 95 % CI, 0.63-0.96), sweet snacks (OR, 0.69; 95 % CI, 0.57-0.82), and alcohol (OR, 0.83; 95 % CI, 0.72-0.95). Furthermore, to reside in a country whose HDI is medium-high was found to be associated as a risk factor for non-compliance with the recommended intake of at least 3 servings of dairy per day, as compared to individuals from countries with very high HDIs (OR, 2.05; 95 % CI, 1.79-2.36). In addition, the results show that being female is a protective factor and is associated with the compliance of the consumption recommendation for dairy products (OR, 0.83; 95 % CI, 0.71-0.98).</p><p><strong>Conclusion: </strong>dairy consumption is related to better diet quality and higher levels of physical activity. Complying with the recommendation to consume 3 servings of dairy per day is associated with better quality of diet, stressing the importance of promoting dairy consumption.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causal relationship between tea intake and bone mineral density at different ages ̶ A Mendelian randomization study.","authors":"Ting Shen, Yining Guan, Jiaru Cai, Yizhou Jin, Yixin Jiang, Jiaying Lin, Chenxin Yan, Jiawei Sun","doi":"10.20960/nh.05661","DOIUrl":"https://doi.org/10.20960/nh.05661","url":null,"abstract":"<p><strong>Introduction: </strong>bone mineral density (BMD) is strongly associated with the risk of osteoporosis and fractures. Furthermore, dietary tea consumption also has a great impact on the variation in BMD. The pathway mechanisms from tea consumption to BMD are not well known. Therefore, we applied a two-sample Mendelian randomization (MR) approach in an attempt to explore the causality between tea consumption and BMD. And then examine whether the effects of tea intake on BMD are specific across different age groups.</p><p><strong>Methods: </strong>we investigated the relationship between tea consumption and BMD using a two-sample Mendelian randomization analysis, utilizing 31 single nucleotide polymorphisms (SNPs) related to tea intake from pooled data from a gene-wide association study (GWAS) of 447,485 British Biobank of European Origin participants, with BMD derived from a meta-analysis of total body BMD and age-specific effects in the Lifelong Genetic Cohort Study (n = 66,628). Causal analysis between tea intake and BMD was performed using MR-Egger, inverse variance weighting (IVW), weighted median, and weighted mode.</p><p><strong>Results: </strong>in IVW, tea consumption has a positive causal effect on total body BMD. However, in different age groups, BMD has a positive effect only within the 45-60-year group. There is no genetic pleiotropy effect of tea intake can have an effect on systemic BMD or among the five different age groups. The Cochran Q statistic and MR-Egger regression were applied to calculate heterogeneity in the IVW method, and no significant heterogeneity was indicated.</p><p><strong>Conclusions: </strong>the results of the MR analysis showed a positive causal effect of tea intake on total body BMD, whereas among the different age groups, tea intake positively affected BMD only in the 45-60 age group, which implies that tea is beneficial in maintaining or increasing BMD in this age group and may reduce osteoporosis and fracture risk.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usefulness of the Mini-Nutritional Assessment tool in screening for sarcopenia in a sample of institutionalized older persons - A comment.","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.20960/nh.05830","DOIUrl":"https://doi.org/10.20960/nh.05830","url":null,"abstract":"","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}