{"title":"A prospective study of regular milk drinking and the risk of all-cause and cause-specific mortality in U.S. adults: findings from the NHANES 2003-2008.","authors":"Fei Zhao, Liyan Zhu, Ye Lu, Hongwei Xia, Shengchao Zhang, Ping Zhang","doi":"10.20960/nh.05623","DOIUrl":"10.20960/nh.05623","url":null,"abstract":"<p><strong>Introduction: </strong>Background: scholars have studied the influences of milk consumption on health. This prospective cohort study evaluated the association between regular milk consumption (RMD) and mortality, including all-cause, cardiovascular disease (CVD), and cancer-specific mortality, in Americans who were aged 20 years and older. Methods: it was attempted to analyze data from the 2003 to 2008 National Health and Nutrition Examination Survey (NHANES), including 8,653 participants with an average follow-up of 160.59 months (standard deviation = 0.96). Regular milk consumption (RMD) was defined as drinking milk at least five times per week. Cox proportional hazards regression models were thereafter utilized for analysis. Results: a significant association was noticeable particularly between RMD and higher rates of all-cause mortality (hazard ratio (HR) = 1.27; 95 % confidence interval (CI): 1.03-1.56; p = 0.03) and cancer mortality (HR = 1.53; 95 % CI: 1.01-2.32; p = 0.04), rather than with CVD mortality (HR = 1.03; 95 % CI: 0.73-1.44; p = 0.84). The association between RMD and all-cause mortality was notably observed across various subgroups in sensitivity and subgroup analyses. Conclusions: these outcomes unveiled the importance of exercising caution with milk consumption, which could be emphasized in public health recommendations.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":"536-543"},"PeriodicalIF":2.5,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexandra Celi, María Trelis Villanueva, Stephany Lanza, José M Soriano, Juan Francisco Merino Torres
{"title":"Impact of tailored dietary interventions on suspected carbohydrate intolerance patients based on genetic testing.","authors":"Alexandra Celi, María Trelis Villanueva, Stephany Lanza, José M Soriano, Juan Francisco Merino Torres","doi":"10.20960/nh.05369","DOIUrl":"10.20960/nh.05369","url":null,"abstract":"<p><strong>Introduction: </strong>Background: carbohydrate intolerance presents a complex scenario where symptoms arise following the consumption of specific substrate and alleviate upon their elimination from the diet. Lactose Intolerance is one of the most prevalent types of food intolerance. Primary lactose intolerance is linked to genetic factors, Lactase Non-Persistence phenotype, while secondary lactose intolerance might be a temporary condition resulting from intestinal damage and loss of disaccharidase activity. Fructose absorption is an energy-independent process, leading to limited and variable absorption. Fructose undergoes quick absorption into the bloodstream through active transporters, specifically GLUT-5 and GLUT-2, found in the initial segment of the small intestine. The management of carbohydrate intolerance requires precise testing methods, accurate diagnostics, and customized dietary interventions. Genetic testing plays a crucial role in determining an individual's genetic profile, helping decide whether permanent restrictions on specific nutrients, such as lactose, are necessary. Objective: this research aims to understand the origin of suspected carbohydrate intolerance, combining genetic testing with breath tests to enhance the efficacy of treatment plans, as customized dietary interventions will be based on the patient's genetic profile and carbohydrate absorption capacity. Material and methods: a combination of genetic testing (lactase non-persistence and celiac disease risk) and breath test for lactose and fructose were performed. Recommendations such as low lactose, low fructose or gluten-free diets; or a combination of them were provided based on each patient's testing profile results. Results: after the nutritional intervention, a significant improvement was noted in all gastrointestinal symptoms, except for reflux and nausea, and in all of the extraintestinal symptoms. Conclusions: designing dietary interventions based on primary and secondary causes for carbohydrate intolerance can avoid unnecessary food restrictions; improving patients' quality of life and treatment effectiveness through tailored dietary interventions.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":"517-526"},"PeriodicalIF":2.5,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emilio Martínez-Almoyna Rifá, Ángel Arturo López González, Pedro Juan Tárraga López, Hernán Paublini, Daniela Vallejos, José Ignacio Ramírez Manent
{"title":"[Relationship between diabesity and elevated values of metabolic-associated steatotic liver disease risk scales in Spanish workers using body mass index and the body adiposity estimator criteria of Clínica de Navarra].","authors":"Emilio Martínez-Almoyna Rifá, Ángel Arturo López González, Pedro Juan Tárraga López, Hernán Paublini, Daniela Vallejos, José Ignacio Ramírez Manent","doi":"10.20960/nh.05441","DOIUrl":"10.20960/nh.05441","url":null,"abstract":"<p><strong>Introduction: </strong>Introduction: diabesity (coexistence of diabetes and obesity) and metabolic associated steatotic liver disease (MASLD) are two very frequent pathologies whose prevalence is increasing every day. Objective: to find out how these two pathological entities are associated in a group of Spanish workers. Methodology: a descriptive, cross-sectional study was carried out in 219477 workers to assess the association between diabesity (applying a double criterion, the body mass index BMI and the Clínica Universitaria de Navarra body adiposity estimator CUN BAE) and different risk scales for MASLD and liver fibrosis. Results: all MASH and liver fibrosis risk scales show higher values in people with diabesity applying the two criteria compared to people without diabesity. Conclusion: diabesity and MASLD and liver fibrosis risk scales show a significant association in our study.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":"485-492"},"PeriodicalIF":2.5,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ying Li, Yuhan Wang, Lianying Guo, Ye Yu, Mengqi Jiang, Lili Deng, Qingyi Zhou, Lu Sun, Xu Feng, Zhuo Zhang
{"title":"Higher frequency of adding salt to foods increases the risk of low bone mineral density in individuals over 60 - A Mendelian randomization study.","authors":"Ying Li, Yuhan Wang, Lianying Guo, Ye Yu, Mengqi Jiang, Lili Deng, Qingyi Zhou, Lu Sun, Xu Feng, Zhuo Zhang","doi":"10.20960/nh.05492","DOIUrl":"10.20960/nh.05492","url":null,"abstract":"<p><strong>Introduction: </strong>Background: Adding salt to foods is associated with an increased osteoporosis risk, but the causality of this relationship remains unknown. Methods: in this study, we conducted a two-sample Mendelian randomization (MR) study to investigate the potential causal effect of adding salt to foods on bone mineral density (BMD). Utilizing data from the UK Biobank to estimate adding salt to foods based on self-reported consumption and genetic association data for BMD from the Genetic Factors for Osteoporosis (GEFOS) consortium, we examined various BMD sites: forearm (distal 1/3 radius), lumbar spine (L1-4), femoral neck, total body BMD (TB-BMD), and age-specific TB-BMD (0-15, 15-30, 30-45, 45-60, and over 60 years). The primary analysis used the inverse variance weighted method, supplemented by sensitivity analyses employing multiple MR methods, MR-PRESSO, and leave-one-out approach. Pleiotropy and heterogeneity were assessed using MR-Egger intercept, funnel plots, Cochran's Q, and Rucker's Q. Results: we found a suggestive association between higher frequency of adding salt to foods and decreased TB-BMD in Europeans over 60 (OR = 0.84, 95 % CI = 0.721-0.979, p = 0.026). This association remained robust across different methods and sensitivity analyses, showing no apparent heterogeneity or pleiotropy. However, no causal effect was detected on BMD in other age groups or skeletal sites. Conclusion: this MR study suggests a higher frequency of adding salt to foods significantly increases low BMD risk in individuals over 60, underscoring the importance of reducing salt consumption in this demographic for osteoporosis prevention.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":"456-463"},"PeriodicalIF":2.5,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Alcohol and tobacco: synergistic factors in breast cancer - A reflection based on scientific evidence].","authors":"Raúl Aguilera-Eguía, Héctor Fuentes-Barria, Cherie Flores-Fernández, Ángel Roco-Videla, Víctor Pérez-Galdavini, Olga Patricia López-Soto","doi":"10.20960/nh.05755","DOIUrl":"10.20960/nh.05755","url":null,"abstract":"<p><strong>Introduction: </strong></p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":"614-615"},"PeriodicalIF":2.5,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Walter Sepúlveda-Loyola, Yshoner Antonio Silva-Díaz, Mário Molari, Erikson Alexander Jiménez Torres, Cintya Odar-Rojas, Denilson Teixeira, Vanessa Probst
{"title":"Association between the fat mass/fat-free mass ratio and muscle strength, static balance and exercise capacity in older adults: a cross-sectional study.","authors":"Walter Sepúlveda-Loyola, Yshoner Antonio Silva-Díaz, Mário Molari, Erikson Alexander Jiménez Torres, Cintya Odar-Rojas, Denilson Teixeira, Vanessa Probst","doi":"10.20960/nh.05616","DOIUrl":"10.20960/nh.05616","url":null,"abstract":"<p><strong>Introduction: </strong>Background: the FM/FFM ratio has been proposed as a new body composition variable. However, the association between FM/FFM ratio and physical function in older adults remains limited. Therefore, the aim of this study was to analyze the association between FM/FFM ratio and muscle strength, static balance, and exercise capacity in older adults. Methods: this was a cross-sectional study involving 392 older adults from Londrina, Brazil. Subjects underwent body composition analysis by bioelectrical impedance, and assessments for aerobic capacity, muscle strength and static balance including the 6-minutes walking test, handgrip strength and one-legged stance test. Statistical analysis was conducted using correlation tests and lineal regression models adjusted for age and gender. The statistical significance considered was p < 0.05. Results: a total of 392 older adults participated (mean age = 69.77 years; women: 74.7 %). The FM/FFM ratio was significantly associated with muscle strength (β = -22.779, 95 % CI: -26.741 to -18.818; p < 0.001), static balance (β = -14.335, 95 % CI: -19.980 to -8.690; p < 0.001), and exercise capacity (β =-98.937, 95 % CI: -152.286 to -45.588, p < 0.001). After adjusting for age and gender, FM/FFM ratio was an important predictor of muscle strength (β = -4.687, 95 % CI: -8.646 to -0.728; p = 0.020) and static balance (β = -18.361, 95 % CI: -24.943 to -11.778; p < 0.001). Conclusions: the FM/FFM ratio is an important clinical measure of body composition that is significantly associated with key indicators of physical performance, including muscle strength, static balance, and exercise capacity in older adults.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":"464-469"},"PeriodicalIF":2.5,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The relationship between adherence to the Mediterranean diet, quality of life, anthropometric measurements, and some biochemical parameters in patients with coronary artery disease.","authors":"Canan Tekin, Hasan Tut, Ayhan Dağ","doi":"10.20960/nh.05857","DOIUrl":"https://doi.org/10.20960/nh.05857","url":null,"abstract":"<p><strong>Objective: </strong>this study aimed to evaluate the relationship between adherence to the Mediterranean diet, quality of life, anthropometric measurements, and biochemical parameters in patients with coronary artery disease (CAD).</p><p><strong>Methods: </strong>a total of 316 adults (≥ 19-91 years-old), 139 (44 %) female and 177 (56 %) male, participated in the study. Three groups were created: the group with normal coronary arteries, the low-medium risk group with 1-69 % stenosis in coronary arteries, and the high-risk group with ≥ 70 % stenosis. In the study, anthropometric and some biochemical parameters were examined. The \"Mediterranean Diet Adherence Screener (MEDAS)\" and the \"Quality of Life Questionnaire (SF-36)\" were used.</p><p><strong>Results: </strong>the maximum mean age of the participants was 61.72 ± 11.03 years in the high CAD risk group, the prevalence of obesity was 58.6% in the low-medium CAD risk group. In the group with normal arteries, MEDAS (p1 < 0.05, p2 < 0.05) and SF-36 scores (physical function, pain, vitality sub-dimensions) were found to be higher (p1 < 0.05). A significant correlation was found between MEDAS and total cholesterol (r = -0.235, p = 0.013), LDL cholesterol (r = 0.212, p = 0.025), social function (r = -0.273, p = 0.006), general health (r = -0.223, p = 0.023), and mental health (r = -0.120, p = 0.033) parameters, but not with other parameters (p > 0.05).</p><p><strong>Conclusions: </strong>disseminating Mediterranean diet as a health policy may be effective in both reducing CAD risk and improving quality of life.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cecilia Arteaga-Pazmiño, Javier Javier Gálvez-Celi, Melisa Sánchez, Noemi Georgina Díaz Menéses, Doménica Salcedo Martínez, Belén Castillo Álava, María Quintana Rodríguez, Samuel Durán-Agüero
{"title":"[Food consumption in the context of an energy crisis: the case of Ecuador].","authors":"Cecilia Arteaga-Pazmiño, Javier Javier Gálvez-Celi, Melisa Sánchez, Noemi Georgina Díaz Menéses, Doménica Salcedo Martínez, Belén Castillo Álava, María Quintana Rodríguez, Samuel Durán-Agüero","doi":"10.20960/nh.05834","DOIUrl":"https://doi.org/10.20960/nh.05834","url":null,"abstract":"<p><strong>Background: </strong>food consumption can be affected during energy crises.</p><p><strong>Objective: </strong>to characterize the food consumption of the Ecuadorian population during the period of electric rationing.</p><p><strong>Methods: </strong>observational and retrospective study. The population consisted of Ecuadorian adults aged 18 and older who resided in cantons of the country during the 2024 electric rationing period. Food consumption was assessed through an online survey validated by experts, with 23 questions about the frequency of food consumption and changes in purchasing and consumption habits by food groups.</p><p><strong>Results: </strong>a total of 550 subjects participated, mainly from urban areas (86.5 %). Of these, 62.2 % were male, and 78.5 % of respondents were aged between 18 and 39 years. 53.3 % reported a reduction in grocery purchases, while 27.8 % increased their purchase of prepared meals. Regarding food groups, 30.9 % consumed vegetables once a day, 24.7 % consumed fruits 2 to 4 times a week, and 33.8 % consumed legumes 2 to 4 times a week. For cereals and tubers, 29.6 % consumed them once a day; 30 % reported consuming fats once a day, and 20.4 % consumed ultra-processed foods once a week; 46.5 % increased food waste, and 76 % changed their consumption of refrigerated products.</p><p><strong>Conclusions: </strong>electric rationing impacted the food consumption of Ecuadorians, especially in dairy, vegetables, and food waste.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cristian Gabriel Álvarez Lepin, Paulina Ibacache-Saavedra, Carolina Fuentes, Macarena Ramos, Claudia Marchant, Lorena Martinez-Ulloa, Lissé Chiquinquirá Angarita-Dávila, Igor Cigarroa, David Andrade, Felipe Caamaño-Navarrete, Guido Contreras-Díaz, Luis Javier Chirosa-Ríos, Pedro Delgado-Floody
{"title":"Skeletal muscle and body fat interact with blood pressure in cerebral vascular disease: characterization study from the Chilean National Health Survey 2016-17.","authors":"Cristian Gabriel Álvarez Lepin, Paulina Ibacache-Saavedra, Carolina Fuentes, Macarena Ramos, Claudia Marchant, Lorena Martinez-Ulloa, Lissé Chiquinquirá Angarita-Dávila, Igor Cigarroa, David Andrade, Felipe Caamaño-Navarrete, Guido Contreras-Díaz, Luis Javier Chirosa-Ríos, Pedro Delgado-Floody","doi":"10.20960/nh.05721","DOIUrl":"https://doi.org/10.20960/nh.05721","url":null,"abstract":"<p><strong>Background: </strong>peripheral (PVD) and cerebral vascular disease (CeVD) are two vascular conditions of relevance in older adults. However, there is little epidemiological studies about the body composition role (i.e., skeletal muscle mass [by calf circumference] and adiposity [by waist circumference]) in the diabetes and hypertension (HTN) prevalence in PVD and CeVD conditions.</p><p><strong>Aim: </strong>to describe the characteristics of population with PVD and CeVD by different body composition phenotypes and determine the interaction between PVD/CeVD, and body composition with the HTN and diabetes prevalence.</p><p><strong>Methods: </strong>a cross-sectional study of the Chilean population based on the National Health Survey 2016-17. A sample size of n = 233 participants was characterized according to previous PVD and CeVD or not No-PVD/No-CeVD history. Four body composition phenotypes were described such as; low skeletal muscle mass plus high waist circumference (Lsmm-Hwc), low skeletal muscle mass plus low waist circumference (Lsmm-Lwc), high skeletal muscle mass plus high waist circumference (Hsmm-Hwc), and high skeletal muscle mass plus low waist circumference (Hsmm-Lwc), by main outcomes as systolic (SBP), and diastolic BP (DBP) and fasting glucose.</p><p><strong>Results: </strong>there was a significant interaction between body composition (Groups x CeVD), in SBP (CeVD, F (3.40), p = 0.002, ES: 0.007), where SBP in Lsmm-Lwc was higher (diff +28 mmHg) versus the Hsmm-Lwc reference group. Lsmm-Hwc (odds ratio [OR], 3.2 [1.8; 5.9], p < 0.0001), Lsmm-Lwc (OR, 1.7 [1.0; 3.1], p = 0.047), and Hsmm-Hwc (OR, 2.2 [1.5; 3.3], p < 0.0001) showed a higher risk for suffering from PVD vs. Hsmm-Lwc group.</p><p><strong>Conclusion: </strong>Chilean adults with both PVD and CeVD are shown to be aged 60, with obesity and hypertensive condition, and report lower handgrip strength in comparison with adult peers with higher muscle mass and lower waist circumference.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of socioeconomic status and nine modifiable lifestyle factors on esophageal cancer risk in European and East Asian populations - Evidence from a comprehensive Mendelian randomization study.","authors":"Ruizhi Ye, Fengming Zhang, Guangxian You","doi":"10.20960/nh.05819","DOIUrl":"https://doi.org/10.20960/nh.05819","url":null,"abstract":"<p><strong>Background and aims: </strong>the intricate relationships between socioeconomic factors, modifiable lifestyle choices, and esophageal cancer risk remain uncertain. We aim to investigate the associations of socioeconomic status, modifiable lifestyle factors, and esophageal cancer risk.</p><p><strong>Methods: </strong>we employed multiple Mendelian randomization (MR) analyses, including three different MR approaches. GWAS databases from European and East Asian populations, encompassing variables such as household income, educational attainment, and the Townsend deprivation index (TDI), were analyzed. The risk of esophageal cancer was assessed using data from three distinct cohorts of European and East Asian descent (Database 1: n = 476,306; Database 2: n = 372,756; Database 3: n = 160,589). Nine modifiable lifestyle factors were incorporated in the multivariable and mediation MR analyses. Meta-analysis was employed to synthesize results across the three datasets.</p><p><strong>Results: </strong>higher household income was connected with a reduced esophageal cancer risk (odds ratio (OR) = 0.698, 95 % confidence interval (95 % CI): 0.556-0.876, p = 0.002). Body mass index (BMI) partially mediated the relationship between household income and the risk of esophageal cancer (OR = 0.914, 95 % CI: 0.841-0.992, p = 0.031, mediation ratio: 27.23 %). However, no significant evidence was found to support a direct association between educational attainment, TDI, and esophageal cancer risk.</p><p><strong>Conclusions: </strong>these findings suggest that higher household income is inversely associated with esophageal cancer risk, with BMI acting as a partial mediator of this relationship. Accordingly, targeted early screening and preventive measures for esophageal cancer should be prioritized among low-income populations, particularly those with obesity.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}