Nutricion hospitalaria最新文献

{"title":"Skeletal muscle and body fat interact with blood pressure in cerebral vascular disease: characterization study from the Chilean National Health Survey 2016-17.","authors":"Cristian Gabriel Álvarez Lepin, Paulina Ibacache-Saavedra, Carolina Fuentes, Macarena Ramos, Claudia Marchant, Lorena Martinez-Ulloa, Lissé Chiquinquirá Angarita-Dávila, Igor Cigarroa, David Andrade, Felipe Caamaño-Navarrete, Guido Contreras-Díaz, Luis Javier Chirosa-Ríos, Pedro Delgado-Floody","doi":"10.20960/nh.05721","DOIUrl":"https://doi.org/10.20960/nh.05721","url":null,"abstract":"<p><strong>Background: </strong>peripheral (PVD) and cerebral vascular disease (CeVD) are two vascular conditions of relevance in older adults. However, there is little epidemiological studies about the body composition role (i.e., skeletal muscle mass [by calf circumference] and adiposity [by waist circumference]) in the diabetes and hypertension (HTN) prevalence in PVD and CeVD conditions.</p><p><strong>Aim: </strong>to describe the characteristics of population with PVD and CeVD by different body composition phenotypes and determine the interaction between PVD/CeVD, and body composition with the HTN and diabetes prevalence.</p><p><strong>Methods: </strong>a cross-sectional study of the Chilean population based on the National Health Survey 2016-17. A sample size of n = 233 participants was characterized according to previous PVD and CeVD or not No-PVD/No-CeVD history. Four body composition phenotypes were described such as; low skeletal muscle mass plus high waist circumference (Lsmm-Hwc), low skeletal muscle mass plus low waist circumference (Lsmm-Lwc), high skeletal muscle mass plus high waist circumference (Hsmm-Hwc), and high skeletal muscle mass plus low waist circumference (Hsmm-Lwc), by main outcomes as systolic (SBP), and diastolic BP (DBP) and fasting glucose.</p><p><strong>Results: </strong>there was a significant interaction between body composition (Groups x CeVD), in SBP (CeVD, F (3.40), p = 0.002, ES: 0.007), where SBP in Lsmm-Lwc was higher (diff +28 mmHg) versus the Hsmm-Lwc reference group. Lsmm-Hwc (odds ratio [OR], 3.2 [1.8; 5.9], p < 0.0001), Lsmm-Lwc (OR, 1.7 [1.0; 3.1], p = 0.047), and Hsmm-Hwc (OR, 2.2 [1.5; 3.3], p < 0.0001) showed a higher risk for suffering from PVD vs. Hsmm-Lwc group.</p><p><strong>Conclusion: </strong>Chilean adults with both PVD and CeVD are shown to be aged 60, with obesity and hypertensive condition, and report lower handgrip strength in comparison with adult peers with higher muscle mass and lower waist circumference.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of socioeconomic status and nine modifiable lifestyle factors on esophageal cancer risk in European and East Asian populations - Evidence from a comprehensive Mendelian randomization study.","authors":"Ruizhi Ye, Fengming Zhang, Guangxian You","doi":"10.20960/nh.05819","DOIUrl":"https://doi.org/10.20960/nh.05819","url":null,"abstract":"<p><strong>Background and aims: </strong>the intricate relationships between socioeconomic factors, modifiable lifestyle choices, and esophageal cancer risk remain uncertain. We aim to investigate the associations of socioeconomic status, modifiable lifestyle factors, and esophageal cancer risk.</p><p><strong>Methods: </strong>we employed multiple Mendelian randomization (MR) analyses, including three different MR approaches. GWAS databases from European and East Asian populations, encompassing variables such as household income, educational attainment, and the Townsend deprivation index (TDI), were analyzed. The risk of esophageal cancer was assessed using data from three distinct cohorts of European and East Asian descent (Database 1: n = 476,306; Database 2: n = 372,756; Database 3: n = 160,589). Nine modifiable lifestyle factors were incorporated in the multivariable and mediation MR analyses. Meta-analysis was employed to synthesize results across the three datasets.</p><p><strong>Results: </strong>higher household income was connected with a reduced esophageal cancer risk (odds ratio (OR) = 0.698, 95 % confidence interval (95 % CI): 0.556-0.876, p = 0.002). Body mass index (BMI) partially mediated the relationship between household income and the risk of esophageal cancer (OR = 0.914, 95 % CI: 0.841-0.992, p = 0.031, mediation ratio: 27.23 %). However, no significant evidence was found to support a direct association between educational attainment, TDI, and esophageal cancer risk.</p><p><strong>Conclusions: </strong>these findings suggest that higher household income is inversely associated with esophageal cancer risk, with BMI acting as a partial mediator of this relationship. Accordingly, targeted early screening and preventive measures for esophageal cancer should be prioritized among low-income populations, particularly those with obesity.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of pediatric simple metabolic syndrome score and metabolic syndrome severity z-scores in identifying metabolic syndrome among obese adolescents.","authors":"Muammer Büyükinan, Sadiye Sert, Ahmet Fatih Yılmaz","doi":"10.20960/nh.05676","DOIUrl":"https://doi.org/10.20960/nh.05676","url":null,"abstract":"<p><strong>Background: </strong>the aim of our study was to evaluate the effectiveness of the pediatric simple metabolic syndrome score (PsiMS) and the metabolic syndrome severity (MetSS) z-score in determining the risk of metabolic syndrome (MetS) in obese adolescents, as well as to assess their correlation with metabolic variables and establish diagnostic cut-offs for MetS.</p><p><strong>Materials and methods: </strong>this prospective cross-sectional study was conducted at two medical centers from March 2024 to June 2024, including a total of 246 obese adolescents.</p><p><strong>Results: </strong>obese adolescents diagnosed with MetS exhibited notably elevated PsiMS and MetSS z-score values. Significant positive correlations were identified between the PsiMS and BMI z-score, total cholesterol, gamma-glutamyl transferase, uric acid, insulin levels, and the Homeostasis Model Assessment of Insulin Resistance (HOMA-IR). Positive relationships were also observed between the MetSS z-score and hip circumference, alanine aminotransferase, gamma-glutamyl transferase, uric acid, insulin, HOMA-IR, and the PsiMS. The PsiMS demonstrated an area under the curve (AUC) of 0.753 with a threshold of 4.5242, resulting in sensitivity and specificity values of 68.2 % and 68.4 %, respectively. The MetSS z-score exhibited an AUC of 0.885 with a threshold of 1.1145, yielding sensitivity and specificity values of 80.7 % and 80.4 %, respectively. The comparison of AUC values between the PsiMS and MetSS z-scores was statistically significant.</p><p><strong>Conclusion: </strong>our findings indicate that the rates of MetS diagnosis using the PsiMS and MetSS z-scores-both continuous metrics for assessing MetS-were significantly higher in adolescents compared to those identified through traditional dichotomous diagnostic methods.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic nomogram for overall survival in resectable gastric cancer: incorporating prognostic nutritional index and fibrinogen.","authors":"Hao Guo, Tingting Wang, Xiaoyang Jiang, Jiajia Wang, Xinghao Ma","doi":"10.20960/nh.05679","DOIUrl":"https://doi.org/10.20960/nh.05679","url":null,"abstract":"<p><strong>Introduction: </strong>Few studies have investigated the combined prognostic value of the prognostic nutritional index (PNI) and plasma fibrinogen (FIB) in predicting long-term survival in patients undergoing radical gastrectomy for gastric cancer.</p><p><strong>Objectives: </strong>This study aimed to examine the association between preoperative PNI, FIB, and overall survival (OS) in patients undergoing radical gastrectomy, and to develop a prognostic nomogram for predicting postoperative OS in gastric cancer (GC) patients.</p><p><strong>Methods: </strong>This retrospective study included 395 patients who underwent radical gastrectomy. Univariate and multivariate Cox proportional hazards regressions were used to identify independent prognostic factors and develop a nomogram for predicting overall survival (OS). The nomogram's accuracy and discriminatory performance were evaluated using the Receiver Operating Characteristic (ROC) curve, concordance index (C-index), and calibration curve. Decision curve analysis (DCA) was also applied to assess its clinical utility.</p><p><strong>Results: </strong>The findings from the multivariate COX regression analysis revealed that preoperative PNI, plasma FIB, nerve invasion, and pathological TNM stage were identified as independent predictive variables for postoperative OS in patients who underwent radical gastrectomy (P<0.05). Patients with high PNI (PNI>49.3) and low FIB (FIB<3.6) had a substantially greater OS. The nomogram, developed from independent prognostic factors, exhibited a C-index of 0.782, surpassing the predictive accuracy of pathological TNM staging alone (C-index = 0.719) in predicting overall survival (OS).</p><p><strong>Conclusions: </strong>The prognostic nomogram incorporating PNI and FIB is a reliable tool for forecasting postoperative survival in GC patients and aiding surgeons in devising individualized treatment strategies.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Atherogenic Plasma indices and their association with cardiovascular risk in postmenopausal women: A population-based study].","authors":"Marcela Sepúlveda González, Samuel Durán Aguero, Lincoyán Fernández-Huerta, Carla Guzmán Pincheira","doi":"10.20960/nh.05738","DOIUrl":"https://doi.org/10.20960/nh.05738","url":null,"abstract":"<p><strong>Introduction: </strong>Menopause represents a critical stage of aging, marked by a decrease in estradiol and progesterone, which contributes to vascular dysfunction, increased blood pressure, accumulation of abdominal fat and hyperlipidemia, resembling the cardiovascular profile of older men.</p><p><strong>Objective: </strong>This study analyzes the relationship between plasma atherogenic indices and cardiovascular risk according to the postmenopausal phase in Chilean women.</p><p><strong>Methods: </strong>A secondary analysis of the National Health Survey 2016-2017 was performed, including women between 40 and 70 years in early or late menopause, classified according to Stages of Reproductive Aging Workshop (STRAW). Lipid profile was analyzed and atherogenic indices were calculated. T-tests, Mann-Whitney and Chi-square tests were applied, considering significance at p<0.05.</p><p><strong>Results: </strong>The sample included 742 menopausal women; 74.4% presented excess malnutrition and 88% abdominal obesity, with an average Body Mass Index (BMI) of 30 kg/m² in both groups. Systolic blood pressure was 8 points higher in late menopause. The atherogenic indices showed significant differences in both stages, with the plasma atherogenic index having the highest correlation.</p><p><strong>Conclusion: </strong>The plasma atherogenic index and the atherogenic coefficient are cost-effective tools for assessing cardiovascular risk in this population.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Albumin-myoestatosis gauge assisted by an artificial intelligence tool as a prognostic factor in patients with metastatic colorectal-cancer].","authors":"Daniel de Luis Román, David Primo, Olatz Izaola Jáuregui, Israel Sánchez Lite, Juan José López Gómez","doi":"10.20960/nh.05687","DOIUrl":"https://doi.org/10.20960/nh.05687","url":null,"abstract":"<p><strong>Objectives: </strong>to evaluate the prognostic role of the marker albumin-myosteatosis (MAM) in Caucasian patients with metastatic colorectal cancer.</p><p><strong>Material and methods: </strong>this study involved 55 consecutive Caucasian patients diagnosed with metastatic colorectal cancer. CT scans at the L3 vertebral level were analyzed to determine skeletal muscle cross-sectional area, skeletal muscle index (SMI), and skeletal muscle density (SMD). Bioelectrical impedance analysis (BIA) (phase angle, reactance, resistance, and SMI-BIA) was used. Albumin and prealbumin were measured. The albumin-myosteatosis marker (AMM = serum albumin (g/dL) × skeletal muscle density (SMD) in Hounsfield units (HU) was calculated. Survival was estimated using the Kaplan-Meier method and comparisons between groups were performed using the log-rank test.</p><p><strong>Results: </strong>the median age was 68.1 ± 9.1 years. Patients were divided into two groups based on the median MAM (129.1 AU for women and 156.3 AU for men). Patients in the low MAM group had significantly reduced values of phase angle and reactance, as well as older age. These patients also had higher rates of malnutrition by GLIM criteria (odds ratio: 3.8; 95 % CI = 1.2-12.9), low muscle mass diagnosed with TC (odds ratio: 3.6; 95 % CI = 1.2-10.9) and mortality (odds ratio: 9.82; 95 % CI = 1.2-10.9). The Kaplan-Meir analysis demonstrated significant differences in 5-year survival between MAM groups (patients in the low median MAM group vs. patients in the high median MAM group), (HR: 6.2; 95 % CI = 1.10-37.5).</p><p><strong>Conclusion: </strong>the marker albumin-myosteatosis (MAM) may function as a prognostic marker of survival in Caucasian patients with metastatic CRC.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The importance of performing intermittent fasting under the supervision of a nutrition professional].","authors":"Ángel Roco-Videla, Raúl Aguilera-Eguía, Mariela Olguín-Barraza, Sergio Flores","doi":"10.20960/nh.05904","DOIUrl":"https://doi.org/10.20960/nh.05904","url":null,"abstract":"","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic research for older persons in resource-limited settings.","authors":"Ashuin Kammar-García, Esmeralda Garza-Santiago, Javier Mancilla-Galindo, Orietta Lizet Segura-Badilla, Martín Lazcano-Hernández, Obdulia Vera-López, Addi Rhode Navarro-Cruz","doi":"10.20960/nh.05865","DOIUrl":"https://doi.org/10.20960/nh.05865","url":null,"abstract":"","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of low-sodium, potassium-rich salt based on the Chinese modified DASH diet on home blood pressure monitoring in patients with hypertension and type 2 diabetes: a clinical trial.","authors":"Li Zhao, Jiaxian An, Wenjun Luo, Ying Mei, Xiaoqing Bu, Shili Xian, Pingping Yu, Huang Yao, Lihong Mu","doi":"10.20960/nh.05681","DOIUrl":"https://doi.org/10.20960/nh.05681","url":null,"abstract":"<p><strong>Objective: </strong>to investigate the impact and safety of Chinese Modified Dietary Approaches to Stop Hypertension (CM-DASH) combined with sodium-restricted formula salts on home blood pressure monitoring (HBPM) in patients with hypertension and type 2 diabetes.</p><p><strong>Design: </strong>employing a semi-open randomized, controlled, single-blind trial, patients were allocated into four groups-Group A (control), Group B (52 % salt), Group C (23 % salt), and Group D (meal packs)-for an eight-week dietary intervention. Throughout the intervention, patients self-measured their blood pressure daily and were followed up weekly. Additionally, 24-hour urine was performed at baseline, week 4, and the end of the intervention.</p><p><strong>Results: </strong>of the 132 initial participants, only two were lost to follow-up. Following an 8-week intervention, blood pressure exhibited a downward trend across all four subject groups (p < 0.05). Both HSBP and HDBP exhibited a more pronounced decrease in group B compared to group A. HSBP decreased the most in group D (-13.06, 95 % CI: -18.84 to 7.64, p < 0.001). The 24-hour urinary Na/K ratios significantly dropped in low-sodium salt participants (p < 0.001). Nevertheless, the differences between the groups were not statistically significant. No serious adverse events were reported throughout the trial.</p><p><strong>Conclusions: </strong>this study's preliminary findings indicate that the CM-DASH dietary pattern combined with 23 % and 52 % sodium-limited formula salts has a beneficial effect on home blood pressure in hypertensive and type 2 diabetes patients. Additionally, it improves patients' urinary sodium and potassium levels and demonstrates safety. However, more studies are needed for validation.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polynomial index of overweight and obesity (IPSO): a novel epidemiological approach to measure and compare BMI/age z-score among populations aged 5-11.","authors":"Marco Antonio Ávila Arcos, Marti Yareli Del Monte Vega, Abelardo Ávila Curiel, Carlos Galindo Gómez, Teresa Shamah-Levy","doi":"10.20960/nh.05653","DOIUrl":"https://doi.org/10.20960/nh.05653","url":null,"abstract":"<p><strong>Introduction: </strong>between 1999 and 2022, the prevalence of overweight and obesity (OW + Ob) in adults increased by more than 20 % in 45 countries, a trend also reflected in the rise of obesity among children and adolescents in 186 countries.</p><p><strong>Objectives: </strong>to compare OW + Ob in the population aged 5 to 11 years over different periods using the polynomial index of overweight and obesity (IPSO).</p><p><strong>Methodology: </strong>cross-sectional anthropometric data from children aged 5-11 years were analyzed using information from the 1999 National Nutrition Survey, the National Health and Nutrition Surveys (ENSANUT 2006-2022), and the National Weight and Height Registry (RNPT 2015-2018). Z-scores for BMI-for-age were calculated based on WHO standards. Means for age and Z-scores were estimated for all ages (60-144 months) across seven intervals. T-SQL scripts were developed to obtain a polynomial regression model and an integral to calculate IPSO values, which were graphically represented.</p><p><strong>Results: </strong>IPSO60-144 increased from 32.5 in 1999 to 50.1 in 2006 and 53.1 in 2022, showing increases across all analyzed age intervals. The RNPT highlighted differences by sex (27.62 for girls vs. 41.57 for boys) and socioeconomic level.</p><p><strong>Conclusions: </strong>IPSO is useful for historical analysis and monitoring the magnitude of obesity in future research, as it enables visualization of OW + Ob trends in school-aged children. It is a key tool for guiding interventions and public policy proposals aimed at reducing OW + Ob in childhood.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}