Nutricion hospitalaria最新文献

Hemodialysis Specific Nutrition Screening Tool (HD-NUT): validity and reliability assesment for Turkey. 血液透析特异性营养筛查工具（HD-NUT）：土耳其的效度和信度评估。

IF 1.1 4区医学

Nutricion hospitalaria Pub Date : 2025-09-25 DOI: 10.20960/nh.05707

Ayfer Beyaz Coşkun, Emine Elibol, Fatih Genç, Pınar Koçkaya

{"title":"Hemodialysis Specific Nutrition Screening Tool (HD-NUT): validity and reliability assesment for Turkey.","authors":"Ayfer Beyaz Coşkun, Emine Elibol, Fatih Genç, Pınar Koçkaya","doi":"10.20960/nh.05707","DOIUrl":"https://doi.org/10.20960/nh.05707","url":null,"abstract":"Background and aims: this study aimed to evaluate the validity and reliability of the Hemodialysis Specific Nutrition Screening Tool (HD-NUT), a new hemodialysis-specific nutrition screening tool for Turkey.Methods: HD-NUT was compared for assessing malnutrition with the Malnutrition Universal Screening Tool (MUST) and Subjective Global Assessment (SGA) in 165 adult patients across two dialysis units. Nutritional status was evaluated using anthropometric measurements and the nurse's opinion was assessed via a survey.Results: HD-NUT was found to be more sensitive than MUST in identifying increased risks of malnutrition and providing dietary guidance. The Cramer V coefficient was 0.445 between MUST and HD-NUT, and 0.487 between SGA and HD-NUT, and indicating compatibility with variables in other screening tools. Significant agreements were found between MUST and HD-NUT (Kappa = 0.409, p = 0.000) and between SGA and HD-NUT (Kappa = 0.290, p = 0.000).Conclusions: HD-NUT is a valid and reliable nutritional screening tool when used by specialist nurses experienced in dialysis units for hemodialysis patients in Turkey.","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145192280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fat content determines the association between milk consumption and cardiovascular disease: Analysis of the NHANES from 2003-2018. 脂肪含量决定了牛奶消费与心血管疾病之间的关系：2003-2018年NHANES分析

IF 1.1 4区医学

Nutricion hospitalaria Pub Date : 2025-09-25 DOI: 10.20960/nh.06027

Jiacan Wu, Yuan Yang, Xuanrui Lin, Guanghong Tao, Xiaoqin Li, Hua Xiao

{"title":"Fat content determines the association between milk consumption and cardiovascular disease: Analysis of the NHANES from 2003-2018.","authors":"Jiacan Wu, Yuan Yang, Xuanrui Lin, Guanghong Tao, Xiaoqin Li, Hua Xiao","doi":"10.20960/nh.06027","DOIUrl":"https://doi.org/10.20960/nh.06027","url":null,"abstract":"Background: the relationship between milk fat content and cardiovascular disease (CVD) remains controversial. This research aimed to examine the relationship between whole (3.5 % fat), reduced-fat (2 % fat), low-fat (1 % fat), and skimmed milk (< 0.5 % fat) and various CVDs.Methods: this cross-sectional analysis was based on data gathered from the 2003-2018 National Health and Nutrition Examination Survey (NHANES), which enrolled 18,282 participants (9,017 men and 9,265 women). Participants were organized into four groups based on the type of milk consumed, as reported in the Diet Behavior and Nutrition Questionnaire. Coronary heart disease (CHD), heart failure (HF), and stroke were assessed via standard questionnaires. Weighted logistic regression models with multivariable adjustment were used to assess the association between varying levels of milk fat content and CVD, adjusting for a range of covariates, including dietary data from two 24-hour dietary recalls. Additionally, interaction, subgroup, and sensitivity analyses were conducted to assess effect modification and test result robustness.Results: after adjusting for confounders, the consumption of whole milk was linked to a reduced prevalence of CHD (odds ratio [OR] = 0.582, 95 % confidence interval [CI] = 0.418-0.810, p = 0.002) than skimmed milk. Furthermore, whole milk consumption was not associated with HF (OR = 1.518, 95 % CI = 0.939-2.455, p = 0.09); however, it was associated with an increased prevalence of stroke (OR = 1.586, 95 % CI = 1.023-2.457, p = 0.039). Subgroup and sensitivity analyses confirmed the reproducibility of our findings.Conclusions: our results suggest that consuming whole milk may be linked to reduced CHD but elevated stroke prevalence compared to skimmed milk.","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145192377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[XVI Jesús Culebras Lecture. Development of eating habits in children: sense and sensitivity]. [十六]Jesús库莱布拉斯讲座。儿童饮食习惯的发展：感觉与敏感[j]。

IF 1.1 4区医学

Nutricion hospitalaria Pub Date : 2025-09-25 DOI: 10.20960/nh.06231

José Manuel Moreno Villares

{"title":"[XVI Jesús Culebras Lecture. Development of eating habits in children: sense and sensitivity].","authors":"José Manuel Moreno Villares","doi":"10.20960/nh.06231","DOIUrl":"https://doi.org/10.20960/nh.06231","url":null,"abstract":"The first years of a child's life are periods of rapid growth and significant neurocognitive development. Adequate energy and macro- and micronutrient intake are essential for proper growth and development. The development of feeding skills is a very sensitive stage that requires, on the one hand, exposure to new foods and different textures and, on the other, an appropriate response from parents to their children's demands and cues. This development of the foundations of eating habits occurs in utero and progresses throughout infancy and early childhood (3 to 5 years). A woman's diet during pregnancy and breastfeeding provides her offspring with their first exposure to flavors. The introduction of complementary foods in the second half of the first year of life is a relevant stage for the acceptance of new flavors and textures and is based on repeated exposure to them. It continues with a phase of incorporation into family meals and culminates in the ability to feed themselves. Disorders in both the lack of food supply or the parents' response can translate into overeating problems and later overweight/obesity, or into changes in eating behavior (rejection of certain foods, restrictive eating, etc.).","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145192248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of scientific validity and appropriateness of artificial intelligence-assisted ChatGPT advices in dietary treatment of methylmalonic acidemia. 人工智能辅助ChatGPT建议治疗甲基丙二酸血症的科学有效性和适宜性评价。

IF 1.1 4区医学

Nutricion hospitalaria Pub Date : 2025-09-24 DOI: 10.20960/nh.06026

Furkan Yolcu, Merve Koç Yekedüz, Engin Köse, Fatima Gülhan Samur, Fatma Tuba Eminoğlu

{"title":"Evaluation of scientific validity and appropriateness of artificial intelligence-assisted ChatGPT advices in dietary treatment of methylmalonic acidemia.","authors":"Furkan Yolcu, Merve Koç Yekedüz, Engin Köse, Fatima Gülhan Samur, Fatma Tuba Eminoğlu","doi":"10.20960/nh.06026","DOIUrl":"https://doi.org/10.20960/nh.06026","url":null,"abstract":"Background and objectives: Chat Generative Pretrained Transformer (ChatGPT) has become an increasingly popular way for patients and healthcare professionals to seek information on health and nutrition advice. Previous studies have raised concerns about the accuracy of dietary advice provided by ChatGPT. We aimed to evaluate the potential of ChatGPT as a tool to provide dietary therapy for methylmalonic acidemia (MMA) in October 2024.Methods and study design: we compared ChatGPT's (version 4.0) dietary advices for MMA with internationally recognized guidelines and current literature, and then evaluated the chatbot's ability to generate dietary therapy in two different cases with MMA. A team of dietitians and metabolic physicians compared ChatGPT responses to disease-specific guidelines and evidence-based resources.Results: overall, ChatGPT provided clear advices: 20.0 % of responses were considered appropriate and 53.4 % were considered inappropriate. Especially in this group of patients whose only known treatment was dietary therapy, the dietary therapy recommended by ChatGPT was also inappropriate for the two cases in question.Conclusions: this study was the first to evaluate the appropriateness of artificial intelligence advices for specialized dietary management of inherited metabolic disorders. Consequently, the idea that artificial intelligence can replace human labor in the near future seems far-fetched, given the low success rate of even a diagnosis with such a clear mechanism and treatment, and individualized treatment approaches.","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145192355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Delayed activation of ankle muscles in young adults with excess adiposity]. [过度肥胖的年轻人踝关节肌肉的延迟激活]。

IF 1.1 4区医学

Nutricion hospitalaria Pub Date : 2025-09-23 DOI: 10.20960/nh.05951

Eduardo Guzmán-Muñoz, Yeny Concha Cisternas, Franco Herrera-Meza, Ignacio Luna-Jara, Pablo Valdés-Badilla, Jordan Hernández-Martínez, Rodrigo Yáñez-Sepúlveda, Felipe Montalva-Valenzuela

{"title":"[Delayed activation of ankle muscles in young adults with excess adiposity].","authors":"Eduardo Guzmán-Muñoz, Yeny Concha Cisternas, Franco Herrera-Meza, Ignacio Luna-Jara, Pablo Valdés-Badilla, Jordan Hernández-Martínez, Rodrigo Yáñez-Sepúlveda, Felipe Montalva-Valenzuela","doi":"10.20960/nh.05951","DOIUrl":"https://doi.org/10.20960/nh.05951","url":null,"abstract":"Introduction: obesity is linked to functional impairments that affect mobility and motor control. Excess body fat may compromise neuromuscular activation; however, its relationship with ankle muscle reaction time in young adults has been scarcely studied.Objectives: to analyze differences in ankle muscle reaction time among young adults according to their body fat percentage (normal, elevated, and very elevated).Methods: a cross-sectional observational study was conducted with 48 young adults. Participants were classified based on body fat percentage. Reaction times of the tibialis anterior, peroneus longus, and medial gastrocnemius were measured using surface electromyography during a sudden ankle inversion test. ANOVA and linear regression were applied to analyze group differences and associations.Results: significant differences were found between groups for the tibialis anterior (p < 0.001), peroneus longus (p = 0.010), and medial gastrocnemius (p < 0.001). The group with very high body fat showed delayed activation in all muscles. Regression analysis revealed that a very high fat percentage was associated with longer reaction times in the tibialis anterior (β = 15.85 ms; p = 0.006), peroneus longus (β = 12.85 ms; p = 0.008), and medial gastrocnemius (β = 17.84 ms; p = 0.007), compared to the normal fat group.Conclusions: a higher body fat percentage is associated with longer muscle reaction times in ankle muscles. This finding highlights the importance of considering body fat percentage as a key factor in assessing and designing neuromuscular interventions for young adults.","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145192217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Excessive weight as a risk factor for COVID-19 severity ‒ A retrospective study. 体重过重是COVID-19严重程度的危险因素——一项回顾性研究

IF 1.1 4区医学

Nutricion hospitalaria Pub Date : 2025-09-23 DOI: 10.20960/nh.05739

Ana Beatriz Vasconcelos de Oliveira, Denise Zaffari, José Antonio Tesser Poloni, Morgana Weber, Rochele Cassanta Rossi, Alexandre Losekann

{"title":"Excessive weight as a risk factor for COVID-19 severity ‒ A retrospective study.","authors":"Ana Beatriz Vasconcelos de Oliveira, Denise Zaffari, José Antonio Tesser Poloni, Morgana Weber, Rochele Cassanta Rossi, Alexandre Losekann","doi":"10.20960/nh.05739","DOIUrl":"https://doi.org/10.20960/nh.05739","url":null,"abstract":"Introduction: obesity is related to cardiovascular disease (CVD) and metabolic disease, and is associated to worsening infectious conditions. In Brazil, more than 50 % of the population is overweight and the obesity prevalence is rising. Since the beginning of the coronavirus pandemic (COVID-19, coronavirus disease 2019), more than 600 million people have been infected, resulting in more than 6.5 million deaths.Objective: this study aimed at evaluating the association between excess weight and clinical prognosis in COVID-19 patients.Method: longitudinal and retrospective cohort study carried out in a hospital in Southern Brazil. Patients were separated into two groups: thinness/eutrophy and overweight/obesity; and demographic, clinical nutritional, biochemical and outcome data were collected from medical records.Results: the average age was 59.3 years, 53.3 % were men and 66.3 % were overweight. The thin/eutrophic group was significantly older and had a higher prevalence of CVD and other comorbidities. The overweight group had significantly more visits to the Intensive Care Unit (ICU). Excess weight, when associated to ICU admission, increased the death risk by 4.16 times, as well as being independently associated to longer ICU visits, the use of mechanical ventilation (MV) and invasive MV, increasing the occurrence of these outcomes by around 30 %.Conclusion: ICU admission was significantly associated to mortality and the strength of this association depended on the presence or absence of overweight/obesity.","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145192342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Specific dietary micronutrients are causally associated with arthritis subtypes: results from the NHANES 2015-2018 and Mendelian randomization study. 特定膳食微量营养素与关节炎亚型有因果关系：来自NHANES 2015-2018和孟德尔随机化研究的结果。

IF 1.1 4区医学

Nutricion hospitalaria Pub Date : 2025-09-23 DOI: 10.20960/nh.05795

Feng Cheng, Yingjia Zhu, Xiaojing Zhang, Fei Xia

{"title":"Specific dietary micronutrients are causally associated with arthritis subtypes: results from the NHANES 2015-2018 and Mendelian randomization study.","authors":"Feng Cheng, Yingjia Zhu, Xiaojing Zhang, Fei Xia","doi":"10.20960/nh.05795","DOIUrl":"https://doi.org/10.20960/nh.05795","url":null,"abstract":"Background: micronutrients (MNs) in the diet are linked to arthritis, but the causal relationships and dose-dependent effects remain unclear.Methods: using the National Health and Nutrition Examination Survey (NHANES) and genome-wide association studies (GWAS) databases, multivariate logistic regression, restricted cubic splines (RCS), and Mendelian randomization (MR) were applied to analyze MNs' impact on arthritis.Results: multivariate logistic regression identified six MNs significantly associated with arthritis: calcium (OR = 0.74 [95 % CI, 0.60, 0.92] p = 0.013), magnesium (OR = 0.74 [95 % CI, 0.62, 0.89] p = 0.003), selenium (OR = 0.62 [95 % CI, 0.50, 0.76] p = 0.0001), folic acid (OR = 0.76 [95 % CI, 0.61, 0.94] p = 0.018), vitamin E (OR = 0.77 [95 % CI, 0.64, 0.92] p = 0.01), vitamin B6 (OR = 0.64 [95 % CI, 0.53, 0.78] p = 0.0001). RCS analysis revealed significant non-linear relationships for vitamin B6, vitamin E, folic acid, and selenium (p < 0.05). MR analysis only confirmed causal associations in specific MNs and subtypes of arthritis: calcium and rheumatoid arthritis (OR = 0.648 [95 % CI, 0.436, 0.962] p = 0.031), vitamin B12 and monoarthritis (OR = 2.876 [95 % CI, 1.240, 6.667] p = 0.014), potassium and pyogenic arthritis (OR = 2.124 [95 % CI, 1.003, 4.497] p = 0.049), vitamin B6 and pyogenic arthritis (OR = 1.744 [95 % CI, 1.034, 2.940] p = 0.037), vitamin B12 and other arthritis (OR = 1.414 [95 % CI, 1.035, 1.932] p = 0.03).Conclusions: this study reveals the causal relationship between specific MNs and certain arthritis subtypes, while also observing dose-dependent associations between other MNs and arthritis. These findings provide valuable insights for dietary interventions and preventive strategies targeting arthritis.","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145192332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Prevalence of perceived stress and its associations with anthropometric and metabolic variables of cardiovascular risk in a young university population]. [在年轻大学人群中，感知压力的患病率及其与心血管风险的人体测量学和代谢变量的关系]。

IF 1.1 4区医学

Nutricion hospitalaria Pub Date : 2025-09-23 DOI: 10.20960/nh.05898

María Guadalupe López-Velázquez, Adriana Aguilar-Galarza, Jorge Palacios-Delgado, Martha Cruz-Soto, Nicolás Camacho-Calderón, Sidhartha Mondragón-Rodriguez, César Campos-Ramírez

{"title":"[Prevalence of perceived stress and its associations with anthropometric and metabolic variables of cardiovascular risk in a young university population].","authors":"María Guadalupe López-Velázquez, Adriana Aguilar-Galarza, Jorge Palacios-Delgado, Martha Cruz-Soto, Nicolás Camacho-Calderón, Sidhartha Mondragón-Rodriguez, César Campos-Ramírez","doi":"10.20960/nh.05898","DOIUrl":"https://doi.org/10.20960/nh.05898","url":null,"abstract":"Objective: to characterize perceived stress using a validated scale and evaluate its associations with anthropometric and metabolic variables.Methods: this is an observational, cross-sectional, one-point study. Participants were recruited using non-probability sampling of university students.Results: the scale was successfully validated with a total of 1,033 participants, 495 men and 538 women. It was found that the entire sample studied presented some level of perceived stress; in men, 4.5 % fell into the low stress category, 85.0 % into moderate stress, and 10.5 % into high stress. In women, 2.8 % fell into the low stress category, 80.1 % into moderate stress, and 17.1 % into high stress; 63.1 % of men had normal weight and 36.9 % were overweight/obese; in women these percentages were 68.3 % and 31.7 %, respectively. A low prevalence of anthropometric and metabolic dysfunctions was observed in both sexes. No associations were found between the variables evaluated and the level of perceived stress except for the amount of skeletal muscle in men.Conclusion: the prevalence of stress in the studied population is alarming since it is known that this mental disorder contributes to the development of various comorbidities, the associations with skeletal muscle in men may be due to hormonal effects on this tissue caused by the perception of stress.","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145192201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Response to the letter to the editor "Web calculator to determine the number of participants in confirmatory factor analysis"]. [回复给编辑的信“确定验证性因子分析参与者人数的网络计算器”]。

IF 1.1 4区医学

Nutricion hospitalaria Pub Date : 2025-09-18 DOI: 10.20960/nh.05978

Lilia Susana Gallardo-Vidal, Marcela Bañuelos-Fonseca, Iris Pineda-Mújica, Adriana Jheny Rodríguez-Méndez, Prishila Danae Reyes-Chávez, Benito Quintero-Valdez

引用次数: 0

[Serum vitamin levels in critically ill patients and their relationship with prognosis]. 危重病人血清维生素水平及其与预后的关系

IF 1.1 4区医学

Nutricion hospitalaria Pub Date : 2025-09-18 DOI: 10.20960/nh.05363

José Garnacho-Montero, M Ascensión González-García, Rafael-Jesús Fernández-Castillo, M Dolores González-Caro, Antonio Gutiérrez-Pizarraya, Teresa Arrobas Velilla, Gloria Salaya Algarín, Malika Tami, Víctor Sánchez-Margalet

{"title":"[Serum vitamin levels in critically ill patients and their relationship with prognosis].","authors":"José Garnacho-Montero, M Ascensión González-García, Rafael-Jesús Fernández-Castillo, M Dolores González-Caro, Antonio Gutiérrez-Pizarraya, Teresa Arrobas Velilla, Gloria Salaya Algarín, Malika Tami, Víctor Sánchez-Margalet","doi":"10.20960/nh.05363","DOIUrl":"https://doi.org/10.20960/nh.05363","url":null,"abstract":"Objectives: to know the serum levels of vitamins (A, D, E, K, B1, B6 and B12) in critically ill patients, their changes, as well as their impact on mortality in the intensive care unit.Methods: prospective study. Serum levels of vitamins A, D, E, K, B1, B6 and B12 were measured at baseline, on day 7 and day 14, as well as the differences in them depending on whether or not the patient received PN (supplemented with a multivitamin complex without vitamin K). Multivariate analysis was performed to study factors related to mortality.Results: 99 patients were analyzed. The median age was 59 years, and 35.4 % (n = 35) were women. Vitamin A, K, and D levels were low on admission; will increase on days 7 and 14, reaching normal values in the first case, but not for K and D. Higher values of NUTRIC score (OR, 1.38; 95 % CI, 1.07-1.77) and vitamin E at income were independently related to a worse and better prognosis, respectively. In patients with PN, vitamin A and E levels rise significantly at 7 and 14 days compared to baseline without significant changes in the rest of the vitamins studied.Conclusions: upon admission to the ICU, the levels of vitamins A, D and K were decreased but those of vitamins B1, B6, B12 and E were normal. Parenteral nutrition with vitamin supplementation, but without vitamin K, maintains adequate serum vitamin K levels. We have only identified as a factor associated with prognosis that basal vitamin E level is a protective factor for mortality.","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145192236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0