Neuroscience bulletin最新文献

A Method for Detecting Depression in Adolescence Based on an Affective Brain-Computer Interface and Resting-State Electroencephalogram Signals. 基于情感脑机接口和静息状态脑电信号的青少年抑郁症检测方法。

IF 5.9 2区医学

Neuroscience bulletin Pub Date : 2024-11-20 DOI: 10.1007/s12264-024-01319-7

Zijing Guan, Xiaofei Zhang, Weichen Huang, Kendi Li, Di Chen, Weiming Li, Jiaqi Sun, Lei Chen, Yimiao Mao, Huijun Sun, Xiongzi Tang, Liping Cao, Yuanqing Li

{"title":"A Method for Detecting Depression in Adolescence Based on an Affective Brain-Computer Interface and Resting-State Electroencephalogram Signals.","authors":"Zijing Guan, Xiaofei Zhang, Weichen Huang, Kendi Li, Di Chen, Weiming Li, Jiaqi Sun, Lei Chen, Yimiao Mao, Huijun Sun, Xiongzi Tang, Liping Cao, Yuanqing Li","doi":"10.1007/s12264-024-01319-7","DOIUrl":"https://doi.org/10.1007/s12264-024-01319-7","url":null,"abstract":"Depression is increasingly prevalent among adolescents and can profoundly impact their lives. However, the early detection of depression is often hindered by the time-consuming diagnostic process and the absence of objective biomarkers. In this study, we propose a novel approach for depression detection based on an affective brain-computer interface (aBCI) and the resting-state electroencephalogram (EEG). By fusing EEG features associated with both emotional and resting states, our method captures comprehensive depression-related information. The final depression detection model, derived through decision fusion with multiple independent models, further enhances detection efficacy. Our experiments involved 40 adolescents with depression and 40 matched controls. The proposed model achieved an accuracy of 86.54% on cross-validation and 88.20% on the independent test set, demonstrating the efficiency of multimodal fusion. In addition, further analysis revealed distinct brain activity patterns between the two groups across different modalities. These findings hold promise for new directions in depression detection and intervention.","PeriodicalId":19314,"journal":{"name":"Neuroscience bulletin","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IsoVISoR: Towards 3D Mesoscale Brain Mapping of Large Mammals at Isotropic Sub-micron Resolution. IsoVISoR：以各向同性亚微米分辨率绘制大型哺乳动物的三维中尺度脑图。

IF 5.9 2区医学

Neuroscience bulletin Pub Date : 2024-11-16 DOI: 10.1007/s12264-024-01316-w

Chao-Yu Yang, Yan Shen, Xiaoyang Qi, Lufeng Ding, Yanyang Xiao, Qingyuan Zhu, Hao Wang, Cheng Xu, Pak-Ming Lau, Pengcheng Zhou, Fang Xu, Guo-Qiang Bi

引用次数: 0

Special Issue Celebrating the 25^th Anniversary of the Institute of Neuroscience, CAS. 庆祝中国科学院神经科学研究所成立 25 周年特刊》。

IF 5.9 2区医学

Neuroscience bulletin Pub Date : 2024-11-13 DOI: 10.1007/s12264-024-01318-8

Ting Lv, Yefei Li, Fei Dong, Shumin Duan

引用次数: 0

Glutamatergic Circuits in the Pedunculopontine Nucleus Modulate Multiple Motor Functions. 脊髓前核中的谷氨酸能回路调节多种运动功能

IF 5.9 2区医学

Neuroscience bulletin Pub Date : 2024-11-11 DOI: 10.1007/s12264-024-01314-y

Yanwang Huang, Shangyi Wang, Qingxiu Wang, Chaowen Zheng, Feng Yang, Lei Wei, Xintong Zhou, Zuoren Wang

{"title":"Glutamatergic Circuits in the Pedunculopontine Nucleus Modulate Multiple Motor Functions.","authors":"Yanwang Huang, Shangyi Wang, Qingxiu Wang, Chaowen Zheng, Feng Yang, Lei Wei, Xintong Zhou, Zuoren Wang","doi":"10.1007/s12264-024-01314-y","DOIUrl":"https://doi.org/10.1007/s12264-024-01314-y","url":null,"abstract":"The functional role of glutamatergic (vGluT2) neurons in the pedunculopontine nucleus (PPN) in modulating motor activity remains controversial. Here, we demonstrated that the activity of vGluT2 neurons in the rostral PPN is correlated with locomotion and ipsilateral head-turning. Beyond these motor functions, we found that these rostral PPN-vGluT2 neurons remarkably respond to salient stimuli. Furthermore, we systematically traced the upstream and downstream projections of these neurons and identified two downstream projections from these neurons to the caudal pontine reticular nucleus/anterior gigantocellular reticular nucleus (PnC/GiA) and the zona incerta (ZI). Our findings indicate that the projections to the PnC/GiA inhibit movement, consistent with 'pause-and-play' behavior, whereas those to the ZI promote locomotion, and others respond to a new 'pause-switch-play' pattern. Collectively, these findings elucidate the multifaceted influence of the PPN on motor functions and provide a robust theoretical framework for understanding its physiological and potential therapeutic implications.","PeriodicalId":19314,"journal":{"name":"Neuroscience bulletin","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142624671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

YAP Signaling in Glia: Pivotal Roles in Neurological Development, Regeneration and Diseases. 胶质细胞中的 YAP 信号：神经发育、再生和疾病中的关键作用。

IF 5.9 2区医学

Neuroscience bulletin Pub Date : 2024-11-06 DOI: 10.1007/s12264-024-01308-w

Lin Lin, Yinfeng Yuan, Zhihui Huang, Yongjie Wang

引用次数: 0

Sonic Hedgehog Mediates High Frequency-Dependent Deep Brain Stimulation for the Correction of Motor Deficits in a Parkinson's Disease Model. 音速刺猬介导高频依赖性深部脑刺激以纠正帕金森病模型的运动障碍

IF 5.9 2区医学

Neuroscience bulletin Pub Date : 2024-11-06 DOI: 10.1007/s12264-024-01306-y

Hui Zhang, Yujuan Su, Zhongwei Qu, Chunkui Zhang, Shaorong Ma, Xia Li, Yizheng Wang

引用次数: 0

Vascular Ossification in the Developing Brain: A Case Study of Pediatric Sturge Weber Syndrome. 发育中大脑的血管骨化：小儿斯特格-韦伯综合征病例研究》。

IF 5.9 2区医学

Neuroscience bulletin Pub Date : 2024-11-06 DOI: 10.1007/s12264-024-01311-1

Ranxi Chen, Shuhui Xie, Jin Gao, Shuli Zhang, Xiaobin Zhang, Yi Yao, Gengxiu Zheng, Fengpeng Wang, Zili Liu, Xuefeng Shen

引用次数: 0

Neurodegenerative Diseases: What Can Be Learned from Toothed Whales? 神经退行性疾病：从齿鲸身上能学到什么？

IF 5.9 2区医学

Neuroscience bulletin Pub Date : 2024-11-01 DOI: 10.1007/s12264-024-01310-2

Simona Sacchini

引用次数: 0

Functional Connectivity Encodes Sound Locations by Lateralization Angles. 功能连接通过侧化角度编码声音位置

IF 5.9 2区医学

Neuroscience bulletin Pub Date : 2024-10-29 DOI: 10.1007/s12264-024-01312-0

Renjie Tong, Shaoyi Su, Ying Liang, Chunlin Li, Liwei Sun, Xu Zhang

{"title":"Functional Connectivity Encodes Sound Locations by Lateralization Angles.","authors":"Renjie Tong, Shaoyi Su, Ying Liang, Chunlin Li, Liwei Sun, Xu Zhang","doi":"10.1007/s12264-024-01312-0","DOIUrl":"https://doi.org/10.1007/s12264-024-01312-0","url":null,"abstract":"The ability to localize sound sources rapidly allows human beings to efficiently understand the surrounding environment. Previous studies have suggested that there is an auditory \"where\" pathway in the cortex for processing sound locations. The neural activation in regions along this pathway encodes sound locations by opponent hemifield coding, in which each unilateral region is activated by sounds coming from the contralateral hemifield. However, it is still unclear how these regions interact with each other to form a unified representation of the auditory space. In the present study, we investigated whether functional connectivity in the auditory \"where\" pathway encoded sound locations during passive listening. Participants underwent functional magnetic resonance imaging while passively listening to sounds from five distinct horizontal locations (-90°, -45°, 0°, 45°, 90°). We were able to decode sound locations from the functional connectivity patterns of the \"where\" pathway. Furthermore, we found that such neural representation of sound locations was primarily based on the coding of sound lateralization angles to the frontal midline. In addition, whole-brain analysis indicated that functional connectivity between occipital regions and the primary auditory cortex also encoded sound locations by lateralization angles. Overall, our results reveal a lateralization-angle-based representation of sound locations encoded by functional connectivity patterns, which could add on the activation-based opponent hemifield coding to provide a more precise representation of the auditory space.","PeriodicalId":19314,"journal":{"name":"Neuroscience bulletin","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142546572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

VTA is the Key to Pain Resilience in Empathic Behavior. VTA是移情行为中疼痛复原力的关键

IF 5.9 2区医学

Neuroscience bulletin Pub Date : 2024-10-28 DOI: 10.1007/s12264-024-01313-z

Xue-Qing Wu, Yi-La Ding, Yu Du, Zhong Chen, Bei Tan

引用次数: 0