Parvalbumin and Somatostatin Neurons in the Thalamic Reticular Nucleus Modulate Visual Information Processing in V1 of Mouse.

IF 5.8 2区 医学 Q1 NEUROSCIENCES
Jiamin Bu, Guangwei Xu, Yifeng Zhou
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引用次数: 0

Abstract

The thalamic reticular nucleus (TRN) plays a crucial role in regulating sensory encoding, even at the earliest stages of visual processing, as evidenced by numerous studies. Orientation selectivity, a vital neural response, is essential for detecting objects through edge perception. Here, we demonstrate that somatostatin (SOM)-expressing and parvalbumin (PV)-expressing neurons in the TRN project to the dorsal lateral geniculate nucleus and modulate orientation selectivity and the capacity for visual information processing in the primary visual cortex (V1). These findings show that SOM-positive and PV-positive neurons in the TRN are powerful modulators of visual information encoding in V1, revealing a novel role for this thalamic nucleus in influencing visual processing.

丘脑网状核中的小白蛋白和生长抑素神经元调节小鼠V1视觉信息加工。
大量研究证明,丘脑网状核(TRN)在调节感觉编码中起着至关重要的作用,甚至在视觉加工的早期阶段。定向选择是一种重要的神经反应,是通过边缘感知来检测物体的关键。在这里,我们证明了TRN中表达生长抑素(SOM)和小白蛋白(PV)的神经元投射到背侧展状核,并调节初级视觉皮层(V1)的定向选择和视觉信息处理能力。这些发现表明,TRN中的som阳性和pv阳性神经元是V1视觉信息编码的强大调节剂,揭示了该丘脑核在影响视觉加工中的新作用。
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来源期刊
Neuroscience bulletin
Neuroscience bulletin NEUROSCIENCES-
CiteScore
7.20
自引率
16.10%
发文量
163
审稿时长
6-12 weeks
期刊介绍: Neuroscience Bulletin (NB), the official journal of the Chinese Neuroscience Society, is published monthly by Shanghai Institutes for Biological Sciences (SIBS), Chinese Academy of Sciences (CAS) and Springer. NB aims to publish research advances in the field of neuroscience and promote exchange of scientific ideas within the community. The journal publishes original papers on various topics in neuroscience and focuses on potential disease implications on the nervous system. NB welcomes research contributions on molecular, cellular, or developmental neuroscience using multidisciplinary approaches and functional strategies. We feature full-length original articles, reviews, methods, letters to the editor, insights, and research highlights. As the official journal of the Chinese Neuroscience Society, which currently has more than 12,000 members in China, NB is devoted to facilitating communications between Chinese neuroscientists and their international colleagues. The journal is recognized as the most influential publication in neuroscience research in China.
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