Noise & HealthPub Date : 2024-04-01Epub Date: 2024-06-21DOI: 10.4103/nah.nah_116_23
Lingli Zhu, Lifeng Zheng
{"title":"Influence of White Sound on Sleep Quality, Anxiety, and Depression in Patients with Schizophrenia.","authors":"Lingli Zhu, Lifeng Zheng","doi":"10.4103/nah.nah_116_23","DOIUrl":"10.4103/nah.nah_116_23","url":null,"abstract":"<p><strong>Background: </strong>Patients with schizophrenia frequently experience issues such as poor sleep quality, anxiety, and depression. White sound has been identified as a potential therapeutic strategy to enhance sleep quality and alleviate negative emotions. This study aimed to investigate the effectiveness of white sound in improving sleep quality, anxiety, and depression among patients with schizophrenia.</p><p><strong>Materials and methods: </strong>This retrospective analysis included clinical data from 212 patients with schizophrenia divided into two groups based on their treatment approach. Group C (control, without white sound, n = 106) received standard pharmacological treatments, while group W (white sound, n = 106) was exposed to white sound (40-50 dB) for 2 hours nightly at 9:00 pm. All patients were assessed using the Pittsburgh Sleep Quality Index (PSQI), Hamilton Depression Scale (HAMD), Hamilton Anxiety Scale (HAMA), and Positive and Negative Syndrome Scale (PANSS) before and after 12 weeks of intervention.</p><p><strong>Results: </strong>After 12 weeks, group W showed significant improvements in sleep latency, sleep efficiency, and overall PSQI scores compared to group C (P < 0.05). Furthermore, the HAMD and HAMA scores were significantly lower in group W (P < 0.05), indicating reduced levels of anxiety and depression. The negative symptoms score was significantly lower in group W (P < 0.05) after treatment.</p><p><strong>Conclusion: </strong>White sound shows promise in improving sleep quality, and alleviating anxiety and depression in patients with schizophrenia.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 121","pages":"97-101"},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11530119/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noise & HealthPub Date : 2024-04-01Epub Date: 2024-06-21DOI: 10.4103/nah.nah_2_24
Beibei Zhang, Qinfang Qu, Yan Shu, Yun Zhang, Jie Zhang, Jia Sun, Caixia Zhang
{"title":"Effect of Wearing Noise-Canceling Headphones on Delivery Process in Natural Childbirth Puerperae: A Single-Center Study.","authors":"Beibei Zhang, Qinfang Qu, Yan Shu, Yun Zhang, Jie Zhang, Jia Sun, Caixia Zhang","doi":"10.4103/nah.nah_2_24","DOIUrl":"10.4103/nah.nah_2_24","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effect of incorporating noise-canceling headphones into the delivery process for natural childbirth puerperae.</p><p><strong>Methods: </strong>We conducted a retrospective analysis of clinical data encompassing natural childbirth puerperae in the People's Hospital of Suzhou New District from January 2021 to February 2023. The implementation of routine noise reduction management was done from January 2021 to January 2022. During this interval, 69 natural childbirth puerperae were selected as subjects, with 7 excluded, resulting in 62 participants constituting the reference group. Subsequently, noise-canceling headphones were distributed to natural childbirth puerperae from February 2022 to February 2023. In this phase, 66 subjects were selected, and 6 were excluded, resulting in 60 participants forming the observation group. Following admission, both groups underwent corresponding nursing management. Emotional states, pain levels, and various indicators were systematically collected and meticulously compared.</p><p><strong>Results: </strong>The observation group exhibited significantly lower Hamilton Anxiety Rating Scale scores than the reference group before delivery and during the first stage of labor (P < 0.05). The observation group demonstrated significantly lower visual analog scale scores and substance P, nitric oxide, and prostaglandin E2 levels than the reference group during the first stage of labor (P < 0.001). During the second stage of labor, the visual analog) scale scores were significantly lower in the observation group than in the reference group (P < 0.05). The durations of first and second labor stages were significantly shorter in the observation group than in the reference group (P < 0.05). No significant difference existed in Apgar scores between the two groups (P > 0.05).</p><p><strong>Conclusion: </strong>The utilization of noise-canceling headphones emerges as an effective intervention, alleviating anxiety, reducing pain during T1, and abbreviating total labor time in natural childbirth puerperae, suggesting its substantial clinical application value and potential as a beneficial addition to maternity care practices.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 121","pages":"142-147"},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11530098/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noise & HealthPub Date : 2024-04-01Epub Date: 2024-06-21DOI: 10.4103/nah.nah_5_24
Yan Xiao, Jing Sun, Guanghua Tao
{"title":"Effects of Soothing Music on the Intraoperative Management of Patients Undergoing Tension-Free Herniorrhaphy: A Retrospective Study.","authors":"Yan Xiao, Jing Sun, Guanghua Tao","doi":"10.4103/nah.nah_5_24","DOIUrl":"10.4103/nah.nah_5_24","url":null,"abstract":"<p><strong>Background: </strong>Noise pollution in the operating room can have adverse effects on the physical and mental well-being of patients. Since the mid-20th century, music therapy has been increasingly used in clinical practice. Soothing music has a beneficial effect in maintaining the efficacy of intraoperative sedation and regulating patients' emotions.</p><p><strong>Objective: </strong>To investigate the effects of soothing music on the intraoperative management of patients undergoing tension-free herniorrhaphy.</p><p><strong>Methods: </strong>We retrospectively analyzed the clinical data of 244 patients who underwent open tension-free herniorrhaphy under local anesthesia at the Fourth Affiliated Hospital of Nanchang University from June 2019 to May 2021. According to the different included time periods, the hospital implemented soothing music management from June 2020 to May 2021, and 110 patients admitted during this period were classified as the study group. One hundred thirty-four patients who underwent clinical routine management from June 2019 to May 2020 were classified as the control group. The patients in the two groups received corresponding management modes during surgery. The perioperative indicators, stress response, anxiety, depression, and clinical efficacy of the two groups were analyzed.</p><p><strong>Results: </strong>No significant differences in the operative time, intraoperative blood loss, postoperative off-bed activity time, and hospitalization time between the two groups (P > 0.05). The study group exhibited lower postoperative cortisol (213.30 (203.40, 229.00) nmol/L) and anxiety (9.00 (7.00, 12.00) points) levels than the control group (246.85 (230.50, 258.40) nmol/L; 14.00 (12.00, 15.00) points) (P < 0.001). Moreover, no significant differences were noted in the norepinephrine and depression levels and the severity of illness, global improvement, and efficacy index scores between the two groups (P > 0.05).</p><p><strong>Conclusion: </strong>Soothing music therapy, as a clinical auxiliary method, has a positive impact on the intraoperative management of patients undergoing open tension-free herniorrhaphy, leading to reduced cortisol levels and alleviation of anxiety.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 121","pages":"198-204"},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11530102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noise & HealthPub Date : 2024-04-01Epub Date: 2024-06-21DOI: 10.4103/nah.nah_98_23
Lina Liu, Shuo Cai, Xiaoyu Wu, Huixin Zhu, Yu Wang
{"title":"Effects of Ward Noise Reduction Administration on Mental Health and Lung Function of Patients with Lung Cancer.","authors":"Lina Liu, Shuo Cai, Xiaoyu Wu, Huixin Zhu, Yu Wang","doi":"10.4103/nah.nah_98_23","DOIUrl":"10.4103/nah.nah_98_23","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to analyze the effects of ward noise reduction administration on the lung function and mental health of patients with lung cancer.</p><p><strong>Methods: </strong>A total of 195 patients who underwent lung cancer surgery in PLA Northern Theater Command Air Force Hospital from November 2020 to November 2022 were selected to be divided into a control group (routine nursing) and an observation group (routine nursing and ward noise reduction administration) in accordance with the medical record system. The general demographic data, noise level, lung function (forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV1/FVC)), and complications of patients in the two groups were collected. Propensity score matching (PSM) was used to balance the baseline data of the two groups, and t-test and chi-square test were used to analyze the data.</p><p><strong>Results: </strong>After PSM was conducted, 50 patients were enrolled in each group. No statistical difference was found in the baseline data, preadministration noise levels, and FEV1, FVC, FEV1/FVC, state-anxiety inventory (S-AI), and trait anxiety inventory scale (T-AI) scores between the two groups (P > 0.05). After ward noise reduction was administered, the noise level in the observation group was lower than that in the control group (P < 0.05). The FEV1, FVC, and FEV1/FVC scores of the observation group were higher than those of the control group but were not statistically significant (P > 0.05). The S-AI and T-AI scores of the observation group were lower than those of the control group (P < 0.05). No differences were found in the complications between the two groups (P > 0.05).</p><p><strong>Conclusion: </strong>Administering ward noise reduction in patients with lung cancer can alleviate their negative emotions, thus worthy of clinical adoption.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 121","pages":"235-241"},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11530107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noise & HealthPub Date : 2024-04-01Epub Date: 2024-06-21DOI: 10.4103/nah.nah_128_23
Xiujuan Zhang, Xiaofang Wang, Ting Liu, Hongwei Ha, Jianxiu Dong, Suhui Ma
{"title":"Effect of Ward Noise Management Combined with Meditation Training on Stroke Rehabilitation Patients.","authors":"Xiujuan Zhang, Xiaofang Wang, Ting Liu, Hongwei Ha, Jianxiu Dong, Suhui Ma","doi":"10.4103/nah.nah_128_23","DOIUrl":"10.4103/nah.nah_128_23","url":null,"abstract":"<p><strong>Objective: </strong>To study the value of ward noise management combined with meditation training in stroke rehabilitation patients.</p><p><strong>Methods: </strong>According to the retrospective analysis method, 150 stroke patients hospitalized in the rehabilitation center of a Tangshan Workers' Hospital from July 2020 to December 2023 were selected as study objects. They were divided into three groups, namely the control group (routine rehabilitation care, n = 50), observation group A (meditation training, n = 50), and observation group B (meditation training and ward noise management, n = 50) according to whether they received ward noise management and meditation training. The general demographic data, Fatigue Severity Scale (FSS), Pittsburgh Sleep Quality Index (PSQI), and the Short Form 36 (SF-36) were collected. Chi-square test and analysis of variance were used to analyse the data.</p><p><strong>Results: </strong>The baseline data of the patients in each group were not statistically significant (P > 0.05). Before treatment, no difference in the FSS, PSQI, SF-36 scores and environmental noise level between the groups (P > 0.05) was observed. After management, the scores of SF-36 in observation group B were higher than those in the control group and observation group A (P < 0.05) except for somatic pain. Other indicators in observation group B were lower than those in the control and observation group A (P < 0.001).</p><p><strong>Conclusions: </strong>Ward noise management and meditation training can effectively reduce patients' fatigue, significantly reducing ambient noise levels, promoting the improvement of life quality, and improving sleep quality.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 121","pages":"107-113"},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11530116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of Ambient Noise Isolation on Illness Severity and Mental Health Among Hospitalized Children with Asthma: Retrospective Study.","authors":"Xiaoqing Li, Yunfang Li, Wenwen Guo, Yanling Zhang","doi":"10.4103/nah.nah_22_24","DOIUrl":"10.4103/nah.nah_22_24","url":null,"abstract":"<p><strong>Objective: </strong>This study investigated the effects of ambient noise isolation on disease severity and mental health among hospitalized children with asthma.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on the clinical data of 187 hospitalized children with asthma admitted from May 2021 to May 2023. Among them, 92 cases were categorized in the control group (conventional management) and 95 in the observation group (environmental noise isolation). Ambient noise level, disease severity, mental health, and sleep quality were observed and compared between the two groups.</p><p><strong>Results: </strong>Weekly time, the noise value of the observation group was lower than that of the control group (P < 0.05). Before the management, modified Tal scoring system, cough symptom score, and Spence Children's Anxiety Scale-Short Version (SCAS-S) were recorded. SCAS-S and Sleep Disturbance Scale for Children (SDSC) had no significant difference (P > 0.05). Weekly time, no differences in the score of social fear dimension of SCAS-S, score of excessive sweating dimension of SDSC, Tal score, and cough symptom score were found between the observation and control groups (P > 0.05). The scores of other dimensions of SCAS-S and SDSC were lower in the observation group than those in the control group (P < 0.05).</p><p><strong>Conclusions: </strong>Environmental noise isolation for hospitalized children with asthma can effectively improve their mental health and sleep status, but this strategy cannot improve their disease.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 121","pages":"128-135"},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11530095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noise & HealthPub Date : 2024-04-01Epub Date: 2024-06-21DOI: 10.4103/nah.nah_36_23
Zhaopeng Yu, Maomin Song
{"title":"Correlation between Long-Term Exposure to Traffic Noise and Risk of Type 2 Diabetes Mellitus.","authors":"Zhaopeng Yu, Maomin Song","doi":"10.4103/nah.nah_36_23","DOIUrl":"10.4103/nah.nah_36_23","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to probe the correlation of long-term exposure to traffic noise with the risk of type 2 diabetes mellitus (T2DM).</p><p><strong>Methods: </strong>The data of 480 community residents collected from April 2017 to April 2018 were retrospectively analyzed. Exposure levels for traffic noise were defined using 24-h mean traffic noise. Logistic regression calculated the association between long-term exposure to traffic noise and the risk of T2DM.</p><p><strong>Results: </strong>Overall, 480 enrolled participants were divided into T2DM (n = 45) and non-T2DM (n = 435) groups. Participants with T2DM were older and more likely to be male, had higher BMI, and were frequent drinkers (P < 0.001). The T2DM group displayed higher exposure to traffic noise than the non-T2DM group (P < 0.001). According to quartiles of traffic noise, all participants were categorized into four groups: Q1 (<51.5 dB), Q2 (51.5-<53.9 dB), Q3 (53.9-<58.0 dB), and Q4 (≥58.0 dB). Prevalence of T2DM was 5.4% in Q1, 7.7% in Q2, 10.3% in Q3, and 14.1% in Q4 groups. Multifactor regression analysis showed that age, BMI, drinking history, and traffic noise exposure are risk factors for T2DM (P < 0.05), whereas sex does not seem to have a significant impact on T2DM (P > 0.05).</p><p><strong>Conclusion: </strong>Long-term exposure to traffic noise may elevate the risk of T2DM. This suggests that long-term exposure to high levels of traffic noise can increase the incidence of diabetes mellitus, which deserves further consideration.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 121","pages":"153-157"},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11530115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noise & HealthPub Date : 2024-04-01Epub Date: 2024-06-21DOI: 10.4103/nah.nah_67_23
Burcu Deniz, Züleyha D Gülmez, Halide Kara, Eyyup Kara
{"title":"Effect of Digital Noise Reduction in Hearing Aids on Speech Intelligibility in Both Quiet and Noisy Environments.","authors":"Burcu Deniz, Züleyha D Gülmez, Halide Kara, Eyyup Kara","doi":"10.4103/nah.nah_67_23","DOIUrl":"10.4103/nah.nah_67_23","url":null,"abstract":"<p><strong>Aims: </strong>Digital noise reduction (DNR) minimizes the effect of noise on speech signals by continuously monitoring frequency bands in the presence of noise. In the present study, we explored the effect of DNR technology on speech intelligibility in individuals using hearing aids (HAs) and investigated implications for daily use.</p><p><strong>Methods and material: </strong>Eighteen participants with bilateral moderate sensorineural hearing loss (aged 16-45 years) were included. Bilateral receiver-in-the-ear HAs were fitted in the participants. The adaptive and nonadaptive (with a signal-to-noise ratio (SNR) of +5 and -5 dB, respectively) Turkish matrix sentence test (TURMatrix) in noise and free-field hearing assessments, including hearing thresholds with hearing aids, speech recognition thresholds (SRT), and speech discrimination scores, were conducted in two different conditions: HA in the DNR-on and DNR-off conditions.</p><p><strong>Results: </strong>No significant difference was observed between free-field hearing assessments with the HA in the DNR-off and DNR-on conditions (P > 0.05). Furthermore, the adaptive and nonadaptive TURMatrix revealed significant differences between the scores under the DNR-on and DNR-off conditions (P < 0.05). Nevertheless, under the DNR-on condition, there was no correlation between free-field hearing assessments with HA and TURMatrix results (P > 0.05). However, a significant correlation was observed between SRT scores with HA and TURMatrix scores (adaptive and nonadaptive, +5 and -5 dB SNR, respectively) under the DNR-off condition (P < 0.05).</p><p><strong>Conclusion: </strong>Our study findings suggest that DNR can improve speech intelligibility in noisy environments. Therefore, DNR can enhance an individual's auditory comfort by improving their capacity to grasp speech in background noise.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 121","pages":"220-225"},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11530118/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noise & HealthPub Date : 2024-04-01Epub Date: 2024-06-21DOI: 10.4103/nah.nah_46_24
Ning Ma, Bo Feng, Ming Li
{"title":"Noise Sensitivity in Cataract Patients: A Retrospective Study.","authors":"Ning Ma, Bo Feng, Ming Li","doi":"10.4103/nah.nah_46_24","DOIUrl":"10.4103/nah.nah_46_24","url":null,"abstract":"<p><strong>Background: </strong>Noise sensitivity results from a series of variables and processes, and it can be used to predict the annoyance caused by noise and health-related outcomes. This study aimed to compare the noise sensitivity between cataract patients and healthy subjects and explore the effect of high noise sensitivity on cataract patients.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on the clinical data of 100 cataract patients and 78 healthy subjects who underwent physical examination in Jiaozhou Central Hospital of Qingdao from February 2020 to February 2023. Noise sensitivity was evaluated by adopting the 8-Item Weinstein Noise Sensitivity Scale (WNSS-8). Comparisons were conducted on the psychological state scores, blood pressure (BP), and heart rate (HR) of the high- (HG) and low-noise-sensitivity (LG) groups.</p><p><strong>Results: </strong>Cataract patients exhibited lower visual acuity (P < 0.001) and higher WNSS-8 scores than the healthy subjects (P < 0.05). On the basis of the median of WNSS-8, the cataract patients were divided into HG (n = 42) and LG (n = 58). Compared with the LG, the HG presented higher Generalized Anxiety Disorder-7 scores, Beck Depression Inventory scores, systolic BP, diastolic BP and HR (P < 0.05).</p><p><strong>Conclusions: </strong>High noise sensitivity in cataract patients may be associated with vision disorders, and it may affect their BP and HR and damage physical and mental health.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 121","pages":"180-185"},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11530094/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noise & HealthPub Date : 2024-04-01Epub Date: 2024-06-21DOI: 10.4103/nah.nah_3_23
Fernanda P Cordeiro, Luciana L M Marchiori, Denilson C Teixeira, Rodrigo A C Andraus, Regina Célia Poli-Frederico
{"title":"Plasma Levels of Interleukin 2 (IL-2) Associated with Hearing Loss Evaluation in the Elderly.","authors":"Fernanda P Cordeiro, Luciana L M Marchiori, Denilson C Teixeira, Rodrigo A C Andraus, Regina Célia Poli-Frederico","doi":"10.4103/nah.nah_3_23","DOIUrl":"10.4103/nah.nah_3_23","url":null,"abstract":"<p><strong>Context: </strong>Presbycusis can be mediated by the effects of inflammatory processes on the auditory system, and these aging biological mechanisms remain poorly studied.</p><p><strong>Aims: </strong>The aim of this study was to determine whether plasma biomarkers are associated with hearing disorders caused by aging in the elderly.</p><p><strong>Settings and design: </strong>Cross-sectional study with 106 participants in the Active Aging Project, 93 (88%) females and 13 (12%) males, with an average age of 70 years.</p><p><strong>Methods and material: </strong>Audiological evaluation was performed with pure tone audiometry and collection of peripheral blood for the measurement of plasma levels of interleukins 2, 4, 6, and 10, tumor necrosis factor-α, and interferon-γ by means of flow cytometry.</p><p><strong>Statistical analysis used: </strong>The SPSS (v.0, SPSS Inc., Chicago, USA) was used for the analysis of the data obtained. For all data analyzed, the significance level adopted was P < 0.05 and 95% confidence interval.</p><p><strong>Results: </strong>There were statistically significant correlations between male and IL-2 (P = 0.031; rs = 0.210), mean II of the right ear (P = 0.004; rs = 0.279), longer in years (P = 0.002; rs = 0.307) and in hours (P = 0.004; rs = 0.281) of noise exposure also in males.</p><p><strong>Conclusions: </strong>In the present study, there was an association between the male gender and higher plasma levels of IL-2, an increase in the average hearing in the right ear, and greater time in years and hours of exposure to noise. There was a predominance of mild sensorineural hearing loss and worsening of hearing related to age, characteristics of presbycusis.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 121","pages":"165-173"},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11530100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}