Effects of Music Therapy in the Context of Positive Emotions, Engagement, Relationships, Meaning and Accomplishment (PERMA) on Negative Emotions in Patients with Mild-to-Moderate Depression.

Objective: This study explores the effects of music therapy under the framework of positive emotions, engagement, relationships, meaning, and accomplishment (PERMA) on the negative emotions and quality of life (QOL) in patients with digestive diseases and mild-to-moderate depression in a general hospital.

Methods: From January 2020 to December 2021, 192 digestive diseases patients with mild-to-moderate depression who met the inclusion criteria were retrospectively analyzed and divided into the control group (routine nursing, n = 90) and the observation group (music therapy under PERMA, n = 102). Hamilton Depression Scale (HAMD-17), Hamilton Anxiety Scale (HAMA), General Well-being Scale, and a 36-item short-form health survey were used to evaluate the negative emotions and QOL of patients. SPSS 25.0 was used for statistical analysis.

Results: At baseline, the general data and the type of digestive disease of the two groups were similar, and no significant difference was noted in the HAMA and HAMD-17 scores (P > 0.05). After 2 weeks of treatment, the HAMA and HAMD-17 scores of the observation group were significantly lower than those of the control group (P < 0.05). In terms of subjective well-being and QOL, the scores of the four dimensions of "satisfaction and interest in life," "melancholy and cheerful mood," "control of emotional behavior" and "relaxation and tension" in the observation group were significantly higher than those in the control group (P < 0.05). In the dimension of "body pain" of QOL, the score of the observation group was significantly higher than that of the control group (P < 0.05).

Conclusion: Among patients in a general hospital with digestive diseases and mild-to-moderate depression, music therapy under the framework of PERMA shows significant positive effects in reducing anxiety and depression symptoms and improving subjective well-being and specific QOL dimensions.