Molecular Plant最新文献_第4页

PLETHORA transcription factors: Stepping into epigenetic bivalent control of rice root meristem. 过多转录因子：涉足水稻根分生组织的表观遗传双价调控。

IF 24.1 1区生物学

Molecular Plant Pub Date : 2026-04-06 Epub Date: 2026-01-22 DOI: 10.1016/j.molp.2026.01.006

Ahamed Khan, Sara Farrona

引用次数: 0

Biology-driven genebank pangenetics meet AI-powered predictions to transform crop breeding 生物学驱动的基因库、泛遗传学与人工智能预测相结合，将改变作物育种

IF 27.5 1区生物学

Molecular Plant Pub Date : 2026-04-02 DOI: 10.1016/j.molp.2026.03.017

Ragavendran Abbai, Thorsten Schnurbusch, Mark Cooper, Manish K. Pandey

引用次数: 0

Single-cell and haplotype-resolved transcriptomics reveal molecular signatures of orchid floral structures 单细胞和单倍型转录组学揭示了兰花花结构的分子特征

IF 27.5 1区生物学

Molecular Plant Pub Date : 2026-04-02 DOI: 10.1016/j.molp.2026.03.016

Yan Li, Songyao Zhang, Bin Zhang, Yuying Yin, Hao Yu

引用次数: 0

The EAR motif-containing adaptor protein ECAP enhances the assembly of PYR1-ABI1 complex to promote ABA signaling in Arabidopsis. 在拟南芥中，含有EAR基序的接头蛋白ECAP可增强PYR1-ABI1复合物的组装，从而促进ABA信号传导。

IF 24.1 1区生物学

Molecular Plant Pub Date : 2026-03-31 DOI: 10.1016/j.molp.2026.03.015

Xing Li, Changjiang Li, Gaofeng Lv, Lei Shi, Shulong Tan, Xi Li, Kaixi Liu, Anxing Li, Lei Zhu, Guanghui Yang, Jigang Li, Ying Fu

{"title":"The EAR motif-containing adaptor protein ECAP enhances the assembly of PYR1-ABI1 complex to promote ABA signaling in Arabidopsis.","authors":"Xing Li, Changjiang Li, Gaofeng Lv, Lei Shi, Shulong Tan, Xi Li, Kaixi Liu, Anxing Li, Lei Zhu, Guanghui Yang, Jigang Li, Ying Fu","doi":"10.1016/j.molp.2026.03.015","DOIUrl":"https://doi.org/10.1016/j.molp.2026.03.015","url":null,"abstract":"The phytohormone abscisic acid (ABA) plays a pivotal role in plant growth, development, and stress responses. In the ABA signaling pathway, ABA-bound PYR1/PYL receptors form complexes with PP2Cs co-receptors, thereby releasing SnRK2 kinases from repression. However, the regulatory factors involved in the assembly of PYR1/PYLs-ABA-PP2Cs complexes remain poorly understood. In this study, phenotypic and genetic analyses indicated that the EAR motif-containing adaptor protein (ECAP) is crucial for plant responses to ABA. High ABA levels significantly upregulated ECAP expression. Furthermore, ECAP was shown to interact with both ABA receptors (PYR1, PYL1/3/11) and PP2Cs (ABI1/2), thus enhancing the formation of the PYR1-ABA-ABI1 complex and consequently exerting efficient inhibition on both the phosphatase activity and protein stability of ABI1. Additionally, phosphatase activity assays revealed that ECAP binding can directly inhibit the phosphatase activity of ABI1/2 in a dose-dependent manner. Collectively, ECAP-mediated inhibition of PP2Cs relieves the suppression of SnRK2s, leading to ABA-responsive physiological effects, including the inhibition of seed germination and root growth, ABA-induced stomatal closure, and enhanced drought tolerance. This study identifies ECAP as a critical regulator in the ABA signaling pathway and elucidates its underlying mechanism, providing new insights into ABA-mediated plant development and stress responses.","PeriodicalId":19012,"journal":{"name":"Molecular Plant","volume":" ","pages":""},"PeriodicalIF":24.1,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147593298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

On the Road to Phenotyping 4.0: from Bottleneck to Breakthrough 在表现型4.0之路上：从瓶颈到突破

IF 27.5 1区生物学

Molecular Plant Pub Date : 2026-03-30 DOI: 10.1016/j.molp.2026.03.014

Weijuan Hu, Yunbi Xu, Xiangdong Fu

引用次数: 0

AI-driven protein engineering: A new paradigm for plant trait design. 人工智能驱动的蛋白质工程：植物性状设计的新范式。

IF 24.1 1区生物学

Molecular Plant Pub Date : 2026-03-25 DOI: 10.1016/j.molp.2026.03.011

Ran Fu, Shan Jiang, Tianhao Wu, Can Yin, Jun Yan, Xiangfeng Wang

{"title":"AI-driven protein engineering: A new paradigm for plant trait design.","authors":"Ran Fu, Shan Jiang, Tianhao Wu, Can Yin, Jun Yan, Xiangfeng Wang","doi":"10.1016/j.molp.2026.03.011","DOIUrl":"10.1016/j.molp.2026.03.011","url":null,"abstract":"Protein engineering modifies protein molecules to achieve specific biological or technological functions. Protein design forms the core methodology, and, in recent years, artificial intelligence (AI)-driven approaches have enabled more precise trait design in plants. This review highlights the convergence of protein structure prediction, generative sequence modeling, and function optimization to create synthetic proteins with improved specificity, stability, and activity in plant systems. We trace the development of protein design from rational design to semi-rational strategies and AI-driven platforms that integrate structure prediction, sequence generation, and de novo design. We discuss eight application areas relevant to plant physiology and breeding: enhanced disease resistance via engineered immune receptors, insect resistance through optimized insecticidal proteins, abiotic stress tolerance through metabolic enzyme stabilization, improved nutrient use via transporter redesign, variant mining for trait fine-tuning, genome-editing system optimization, environmental sensing with synthetic biosensors, and programmable regulatory circuits for plant factories (including controlled environment agriculture). Across these areas, we summarize design principles, advances, and translational considerations, emphasizing how AI expands sequence space and improves candidate prioritization. We also address current bottlenecks, including domain shift, reliability gaps in generative models, limited portability, the genotype-to-phenotype gap, and design-to-validation workflow constraints. Finally, we propose a staged roadmap for AI-driven plant trait design and outline the milestones and requirements for translation into breeding.","PeriodicalId":19012,"journal":{"name":"Molecular Plant","volume":" ","pages":""},"PeriodicalIF":24.1,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147521389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

BSMT1, SABP3, and MAT2 assemble into a ternary complex vital for methyl salicylate biosynthesis and airborne defense BSMT1， SABP3和MAT2组装成对水杨酸甲酯生物合成和空气防御至关重要的三元配合物

IF 27.5 1区生物学

Molecular Plant Pub Date : 2026-03-10 DOI: 10.1016/j.molp.2026.03.004

Baolong Sun, Wei Yang, Luyue Shang, Haimiao Zhang, Yang Liu, Lansu Wei, Yihan Zhang, Boyu Zhao, Yong Wang, Ziyi Yin, Chongchong Lu, Haipeng Zhao, Yang Li, Zhengqing Fu, Xinhua Ding

{"title":"BSMT1, SABP3, and MAT2 assemble into a ternary complex vital for methyl salicylate biosynthesis and airborne defense","authors":"Baolong Sun, Wei Yang, Luyue Shang, Haimiao Zhang, Yang Liu, Lansu Wei, Yihan Zhang, Boyu Zhao, Yong Wang, Ziyi Yin, Chongchong Lu, Haipeng Zhao, Yang Li, Zhengqing Fu, Xinhua Ding","doi":"10.1016/j.molp.2026.03.004","DOIUrl":"https://doi.org/10.1016/j.molp.2026.03.004","url":null,"abstract":"When plants encounter biotic and abiotic stresses, they emit various volatile organic compounds (VOCs) to communicate with nearby plants and activate airborne defenses (AD). One critical compound in this process is methyl salicylate (MeSA). Previous studies have mostly examined how stress triggers the production of MeSA at the gene level. In our study, we found that MeSA plays a key role in AD during bacterial infections and determined how plants boost MeSA production through a protein complex. Infection by <ce:italic>Pseudomonas syringae</ce:italic> pv. <ce:italic>tomato</ce:italic> DC3000 (<ce:italic>Pst</ce:italic> DC3000) in <ce:italic>Arabidopsis thaliana</ce:italic> increased salicylic acid (SA) levels, leading to the formation of a ternary protein complex in the cytoplasm. This complex consists of benzoic acid/salicylic acid carboxyl methyltransferases (BSMT1), salicylic acid-binding protein 3 (SABP3), and S-adenosylmethionine synthetase 2 (MAT2). Together, they enhance MAT2's ability to produce S-adenosyl methionine (SAM), a precursor to MeSA, and boost BSMT1's capacity to synthesize MeSA. The produced MeSA then triggers AD in nearby plants and initiates systemic acquired resistance (SAR) in the infected plant. Our findings clarify the MeSA production pathway during pathogen attacks and show that MeSA-mediated AD is a common defense against both insect and pathogen threats, emphasizing its potential as a potent plant immune inducer.","PeriodicalId":19012,"journal":{"name":"Molecular Plant","volume":"78 1","pages":""},"PeriodicalIF":27.5,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147392612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tasting trouble: Rethinking how plants sense salt and drought. 品尝麻烦：重新思考植物如何感知盐和干旱。

IF 24.1 1区生物学

Molecular Plant Pub Date : 2026-03-03 DOI: 10.1016/j.molp.2026.02.014

Sofía Ortega, Yu Him Tang, Christa Testerink

引用次数: 0

Regulating the regulators: How expression control improves regeneration with developmental genes. 调控调控：表达调控如何提高发育基因的再生。

IF 24.1 1区生物学

Molecular Plant Pub Date : 2026-03-02 Epub Date: 2025-12-15 DOI: 10.1016/j.molp.2025.12.012

Megan Kelly, Ryan A Nasti

引用次数: 0

Conserved and divergent: Salicylic acid biosynthesis and signaling pathways across the plant kingdom. 保守与分化：水杨酸在植物界的生物合成和信号通路。