Molecular Plant最新文献

Recognition of a phytocytokine by the DEPR1-SERK2 receptor complex confers multi-pathogen resistance in wheat. DEPR1-SERK2受体复合物对植物细胞因子的识别赋予小麦对多种病原体的抗性。

IF 24.1 1区生物学

Molecular Plant Pub Date : 2025-10-11 DOI: 10.1016/j.molp.2025.10.005

Lijun Wang, Jun Zhao, Chuanchun Yin, Hongxu Li, Yanan Xiao, Cuicui Du, Zhaoxi Lu, Yongjian Zhang, Fangshuai Jia, Jiaxin Hao, Jinghui Yan, Yi Zhang, Jian Li, Xinhua Ding, Zhihu Han, Haitao Cui, Jijie Chai, Xingwang Deng, Cheng Chi, Shuguo Hou

{"title":"Recognition of a phytocytokine by the DEPR1-SERK2 receptor complex confers multi-pathogen resistance in wheat.","authors":"Lijun Wang, Jun Zhao, Chuanchun Yin, Hongxu Li, Yanan Xiao, Cuicui Du, Zhaoxi Lu, Yongjian Zhang, Fangshuai Jia, Jiaxin Hao, Jinghui Yan, Yi Zhang, Jian Li, Xinhua Ding, Zhihu Han, Haitao Cui, Jijie Chai, Xingwang Deng, Cheng Chi, Shuguo Hou","doi":"10.1016/j.molp.2025.10.005","DOIUrl":"https://doi.org/10.1016/j.molp.2025.10.005","url":null,"abstract":"The recognition of plant-derived immunogenic peptides, known as phytocytokines (PCKs), with cell surface-resident receptors triggers immune signaling pathways that bolster the plant's basal defense against pathogens. However, the molecular mechanism underlying PCK-mediated immune regulation in wheat remains largely unexplored. In this study, we identified a wheat PCK, Delta-like PCK (DEP), which robustly activates immune responses and confers multi-pathogen resistance in wheat. DEP is perceived by the leucine-rich repeat (LRR)-receptor kinases (RKs) DEP RECEPTOR 1 (DEPR1) and SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE 2 (SERK2) and triggers DERP1- and SERK2-dependent immune signaling. Cryogenic electron microscopy (cryo-EM) analysis revealed that DEP2 binds to the extracellular LRR domain of DEPR1 and recruits SERK2 through a disulfide bond-stabilized loop to promote DEPR1-SERK2 heterodimerization. Furthermore, we showed that the DEP2-DEPR1-SERK2 module confers wheat disease resistance to Xanthomonas translucens, Fusarium graminearum, and Fusarium pseudograminearum. We also demonstrated that this module enhances wheat resistance to X. translucens by antagonizing abscisic acid (ABA) signaling. This work elucidates a novel phytocytokine-mediated immune signaling pathway and provides a promising strategy for inducing multi-pathogen resistance in wheat.","PeriodicalId":19012,"journal":{"name":"Molecular Plant","volume":" ","pages":""},"PeriodicalIF":24.1,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145275394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reversible S-acylation of BONZAI1 orchestrates the internalization of immune receptors to balance plant development and immunity. BONZAI1可逆s酰化调控免疫受体内化，平衡植物发育和免疫。

IF 24.1 1区生物学

Molecular Plant Pub Date : 2025-10-10 DOI: 10.1016/j.molp.2025.10.006

Xiaoshi Liu, Zhiying Wang, Shihui Li, Panpan Li, Meiqi Yuan, Xiaolin Lu, Chi Li, Yuewen Zheng, Zhendan Cao, Chuanliang Liu, Hongbo Li, Chao Wang, Caiji Gao, Chengwei Yang, Jianbin Lai

{"title":"Reversible S-acylation of BONZAI1 orchestrates the internalization of immune receptors to balance plant development and immunity.","authors":"Xiaoshi Liu, Zhiying Wang, Shihui Li, Panpan Li, Meiqi Yuan, Xiaolin Lu, Chi Li, Yuewen Zheng, Zhendan Cao, Chuanliang Liu, Hongbo Li, Chao Wang, Caiji Gao, Chengwei Yang, Jianbin Lai","doi":"10.1016/j.molp.2025.10.006","DOIUrl":"https://doi.org/10.1016/j.molp.2025.10.006","url":null,"abstract":"Plants have developed a precise immunity system for disease resistance and the receptors on the plasma membrane is controlled by endocytosis to modulate immune signaling, but endocytosis regulation in this process is unclear. Here we uncover that reversible S-acylation of BONZAI1 (BON1), a conserved copine family protein for development-immunity balance in Arabidopsis, contributes to accurate control of endocytosis. BON1 is targeted by S-acylation, a type of protein lipidation, for its localization on the plasma membrane and its function in development and immunity. Furthermore, the S-acylation status of BON1 affects its association with a light-chain clathrin subunit CLC3 and regulates endocytosis. Specifically, PAT14 facilitates the S-acylation of BON1, while ABAPT11 mediates its de-S-acylation. A physiological level of this reversible S-acylation of BON1 is essential for endocytosis and the internalization of immune receptors. Interestingly, salicylic acid enhances the ABAPT11-dependent de-S-acylation of BON1 for amplifying immunity signaling. This work on endocytosis regulation in plant development-immunity balance would assist with the improvement of crop yields and disease resistance.","PeriodicalId":19012,"journal":{"name":"Molecular Plant","volume":" ","pages":""},"PeriodicalIF":24.1,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145275391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the maize transcriptional regulatory landscape through large-scale profiling of transcription factor binding sites. 通过转录因子结合位点的大规模分析探索玉米转录调控景观。

IF 24.1 1区生物学

Molecular Plant Pub Date : 2025-10-06 Epub Date: 2025-08-12 DOI: 10.1016/j.molp.2025.08.009

Qiang Huo, Ziru Zhang, Kechun Zhang, Qun Wang, Weixiao Zhang, Xinyu Ye, Qingya Lyu, David W Galbraith, Zeyang Ma, Rentao Song

{"title":"Exploring the maize transcriptional regulatory landscape through large-scale profiling of transcription factor binding sites.","authors":"Qiang Huo, Ziru Zhang, Kechun Zhang, Qun Wang, Weixiao Zhang, Xinyu Ye, Qingya Lyu, David W Galbraith, Zeyang Ma, Rentao Song","doi":"10.1016/j.molp.2025.08.009","DOIUrl":"10.1016/j.molp.2025.08.009","url":null,"abstract":"Understanding gene regulatory networks (GRNs) is essential for improving maize yield and quality through molecular breeding approaches. The lack of comprehensive transcription factor (TF)-DNA interaction data has hindered accurate GRN predictions, limiting our insight into the regulatory mechanisms. In this study, we performed large-scale profiling of maize TF binding sites. We obtained and collected reliable binding profiles for 513 TFs, identified 394,136 binding sites, and constructed an accuracy-enhanced maize GRN (mGRN+) by integrating chromatin accessibility and gene expression data. The mGRN+ comprises 397,699 regulatory relationships. We further divided the mGRN+ into multiple modules across six major tissues. Using machine-learning algorithms, we optimized the mGRN+ to improve the prediction accuracy of gene functions and key regulators. Through independent genetic validation experiments, we further confirmed the reliability of these predictions. This work provides the largest collection of experimental TF binding sites in maize and highly optimized regulatory networks, which serve as valuable resources for studying maize gene function and crop improvement.","PeriodicalId":19012,"journal":{"name":"Molecular Plant","volume":" ","pages":"1777-1798"},"PeriodicalIF":24.1,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144847628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How plants discriminate mutualistic symbiosis from immunity. 植物如何区分共生与免疫。

IF 24.1 1区生物学

Molecular Plant Pub Date : 2025-10-06 Epub Date: 2025-08-12 DOI: 10.1016/j.molp.2025.08.005

Anil Kumar, Jin-Peng Gao, Jeremy D Murray

引用次数: 0

Silent in code, loud in effect: How epitranscriptomic regulation sculpted cucumber domestication. 沉默的代码，响亮的效果：表转录组调控如何塑造黄瓜驯化。

IF 24.1 1区生物学

Molecular Plant Pub Date : 2025-10-06 Epub Date: 2025-08-30 DOI: 10.1016/j.molp.2025.08.015

Adnane Boualem, Abdelhafid Bendahmane

引用次数: 0

Beyond nitrate: NRT1.1B as an ABA receptor. 超越硝酸盐：nrt11 - 1b作为ABA受体。

IF 24.1 1区生物学

Molecular Plant Pub Date : 2025-10-06 Epub Date: 2025-08-14 DOI: 10.1016/j.molp.2025.08.010

Han-Qing Wang, Sheng Luan

引用次数: 0

Population genomic analysis unravels the repeated trait evolution after the centric origin of African cultivated rice. 群体基因组分析揭示了非洲栽培稻中心起源后的重复性状进化。

IF 24.1 1区生物学

Molecular Plant Pub Date : 2025-10-06 Epub Date: 2025-08-14 DOI: 10.1016/j.molp.2025.08.008

Wenkai Luo, Jiayu Gao, Liangcai Leng, Jing Ning, Wei He, Leqin Chang, Zuofeng Zhu

{"title":"Population genomic analysis unravels the repeated trait evolution after the centric origin of African cultivated rice.","authors":"Wenkai Luo, Jiayu Gao, Liangcai Leng, Jing Ning, Wei He, Leqin Chang, Zuofeng Zhu","doi":"10.1016/j.molp.2025.08.008","DOIUrl":"10.1016/j.molp.2025.08.008","url":null,"abstract":"The origin of African cultivated rice (Oryza glaberrima) has been debated for over half a century, with many aspects of its domestication process remaining unclear. Through an extensive population analysis of 494 accessions, we found that African cultivated rice was domesticated from a subgroup of wild rice in Mali, supporting a centric origin model. The genetic divergence between cultivated rice and its wild progenitor occurred approximately 3000-3500 years BP, followed by a wide geographical expansion 1500-2100 years BP. The non-shattering phenotype, a key domestication trait in cereals, was found to evolve repeatedly, likely at different times and locations. We also identified two genes (OgBh4 and OgPhr1) and six types of causal mutations responsible for the transition of hull color, another important domestication trait, and showed that these were also repeatedly selected across different local groups of rice accessions. These findings provide new insights into the evolutionary history of African cultivated rice and emphasize the importance of repeated trait evolution in crop domestication.","PeriodicalId":19012,"journal":{"name":"Molecular Plant","volume":" ","pages":"1672-1687"},"PeriodicalIF":24.1,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

OsSPT38 encodes a novel SUMO E3 ligase that improves rice stress resilience and grain yield. OsSPT38编码一种新的SUMO E3连接酶，可以提高水稻的抗逆性和粮食产量。

IF 24.1 1区生物学

Molecular Plant Pub Date : 2025-10-06 Epub Date: 2025-09-03 DOI: 10.1016/j.molp.2025.08.019

Zi-Sheng Zhang, Zheng-Yi Zhang, Jin-Qiu Xia, Si-Yan Chen, Liang-Qi Sun, Jie Wu, Da-Yu He, Jing-Xian Wang, Qin-Yu Liang, Lei Wang, Ke Ruan, Tian Sang, Peng-Cheng Wang, Shi-Mei Wang, Jun Fang, Guo-Jun Pan, Ping Xu, Cheng-Bin Xiang

{"title":"OsSPT38 encodes a novel SUMO E3 ligase that improves rice stress resilience and grain yield.","authors":"Zi-Sheng Zhang, Zheng-Yi Zhang, Jin-Qiu Xia, Si-Yan Chen, Liang-Qi Sun, Jie Wu, Da-Yu He, Jing-Xian Wang, Qin-Yu Liang, Lei Wang, Ke Ruan, Tian Sang, Peng-Cheng Wang, Shi-Mei Wang, Jun Fang, Guo-Jun Pan, Ping Xu, Cheng-Bin Xiang","doi":"10.1016/j.molp.2025.08.019","DOIUrl":"10.1016/j.molp.2025.08.019","url":null,"abstract":"Abiotic stresses threaten global food security, underscoring the requirement for resilient crop varieties. In this study, we identified OsSPT38, a previously uncharacterized SUMO E3 ligase in rice, and discovered a gain-of-function mutation (Gly212Asp) of OsSPT38 that enhances rice stress resilience and yield. The phenotypic effects of this mutation were validated in 18 independent mutants and by base editing in the elite indica cultivar Huanghuazhan. Among 4774 rice accessions, the Gly212Asp mutation was identified exclusively in seven japonica varieties, demonstrating its rarity and recent evolutionary origin. Functional analyses showed that OsSPT38 interacts with the SUMO E2 enzyme OsSCE3 and stress-associated proteins to promote their SUMOylation, thereby stabilizing target proteins. The Gly212Asp allele (OsSPT38D) displayed greater activity than the wild-type allele. These findings uncover OsSPT38 as a key regulator of abiotic stress adaptation and underscore Gly212Asp as a promising molecular target for breeding high-yielding stress-resilient rice varieties.","PeriodicalId":19012,"journal":{"name":"Molecular Plant","volume":" ","pages":"1742-1758"},"PeriodicalIF":24.1,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145001052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PEDUNCLE LENGTH 1 regulates wheat peduncle elongation through brassinosteroid signaling pathway. pedduncle LENGTH 1通过油菜素内酯信号通路调控小麦梗伸长。

IF 24.1 1区生物学

Molecular Plant Pub Date : 2025-10-06 Epub Date: 2025-09-04 DOI: 10.1016/j.molp.2025.09.003

Hong Liu, Liya Zhi, Hualiang Qiao, Yanxiao Niu, Jianxiu Shang, Hao Zhang, Wenzhao Xie, Yazhou Xuan, Wenqing Li, Jijie Li, Xinyu Zhang, Liuge Xue, Dongtao Liu, Hongbo Ma, Jun Ji, Lei Wang, Baowen Zhang, Chunjiang Zhou, Xigang Liu, Wenqiang Tang, Junming Li, Na Zhang

引用次数: 0

The inheritance of acquired cold tolerance in rice supports Darwin's hypotheses. 水稻获得性耐寒性的遗传支持了达尔文的假说。

IF 24.1 1区生物学

Molecular Plant Pub Date : 2025-10-06 Epub Date: 2025-09-05 DOI: 10.1016/j.molp.2025.09.001

Runrun Sun, Yongsheng Liu

引用次数: 0