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Nano- and microplastics: a comprehensive review on their exposure routes, translocation, and fate in humans 纳米和微塑料:对其在人类中的暴露途径、迁移和命运的全面综述
IF 4.9 3区 环境科学与生态学
NanoImpact Pub Date : 2023-01-01 DOI: 10.1016/j.impact.2022.100441
Anja F.R.M. Ramsperger , Enrico Bergamaschi , Marco Panizzolo , Ivana Fenoglio , Francesco Barbero , Ruud Peters , Anna Undas , Sebastian Purker , Bernd Giese , Carina R. Lalyer , Alba Tamargo , M. Victoria Moreno-Arribas , Hans-Peter Grossart , Dana Kühnel , Jana Dietrich , Friedrich Paulsen , Anani K. Afanou , Shan Zienolddiny-Narui , Stine Eriksen Hammer , Torunn Kringlen Ervik , Christian Laforsch
{"title":"Nano- and microplastics: a comprehensive review on their exposure routes, translocation, and fate in humans","authors":"Anja F.R.M. Ramsperger ,&nbsp;Enrico Bergamaschi ,&nbsp;Marco Panizzolo ,&nbsp;Ivana Fenoglio ,&nbsp;Francesco Barbero ,&nbsp;Ruud Peters ,&nbsp;Anna Undas ,&nbsp;Sebastian Purker ,&nbsp;Bernd Giese ,&nbsp;Carina R. Lalyer ,&nbsp;Alba Tamargo ,&nbsp;M. Victoria Moreno-Arribas ,&nbsp;Hans-Peter Grossart ,&nbsp;Dana Kühnel ,&nbsp;Jana Dietrich ,&nbsp;Friedrich Paulsen ,&nbsp;Anani K. Afanou ,&nbsp;Shan Zienolddiny-Narui ,&nbsp;Stine Eriksen Hammer ,&nbsp;Torunn Kringlen Ervik ,&nbsp;Christian Laforsch","doi":"10.1016/j.impact.2022.100441","DOIUrl":"10.1016/j.impact.2022.100441","url":null,"abstract":"<div><p>Contamination of the environment with nano-and microplastic particles (NMPs) and its putative adverse effects on organisms, ecosystems, and human health is gaining increasing scientific and public attention. Various studies show that NMPs occur abundantly within the environment, leading to a high likelihood of human exposure to NMPs. Here, different exposure scenarios can occur. The most notable exposure routes of NMPs into the human body are via the airways and gastrointestinal tract (GIT) through inhalation or ingestion, but also via the skin due to the use of personal care products (PCPs) containing NMPs. Once NMPs have entered the human body, it is possible that they are translocated from the exposed organ to other body compartments. In our review article, we combine the current knowledge on the (1) exposure routes of NMPs to humans with the basic understanding of the potential (2) translocation mechanisms into human tissues and, consequently, their (3) fate within the human body. Regarding the (1) exposure routes, we reviewed the current knowledge on the occurrence of NMPs in food, beverages, personal care products and the air (focusing on indoors and workplaces) and found that the studies suggest an abundant presence of MPs within the exposure scenarios. The overall abundance of MPs in exposure matrices relevant to humans highlights the importance of understanding whether NMPs have the potential for tissue translocation. Therefore, we describe the current knowledge on the potential (2) translocation pathways of NMPs from the skin, GIT and respiratory systems to other body compartments. Here, particular attention was paid to how likely NMPs can translocate from the primary exposed organs to secondary organs due to naturally occurring defence mechanisms against tissue translocation. Based on the current understanding, we conclude that a dermal translocation of NMPs is rather unlikely. In contrast, small MPs and NPs can generally translocate from the GIT and respiratory system to other tissues. Thus, we reviewed the existing literature on the (3) fate of NMPs within the human body. Based on the current knowledge of the contamination of human exposure routes and the potential translocation mechanisms, we critically discuss the size of the detected particles reported in the fate studies. In some cases, the particles detected in human tissue samples exceed the size of a particle to overcome biological barriers allowing particle translocation into tissues. Therefore, we emphasize the importance of critically reading and discussing the presented results of NMP in human tissue samples.</p></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9666998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
Characterization of aerosolized particles in effluents from carbon fibre composites incorporating nanomaterials during simultaneous fire and impact 在同时发生火灾和撞击过程中,含有纳米材料的碳纤维复合材料流出物中雾化颗粒的表征
IF 4.9 3区 环境科学与生态学
NanoImpact Pub Date : 2023-01-01 DOI: 10.1016/j.impact.2022.100446
R. Chapple , C. Chivas-Joly , J.-C. Roux , L. Dumazert , L. Ferry , J.-M. Lopez-Cuesta , E.L. Erskine , B.K. Kandola
{"title":"Characterization of aerosolized particles in effluents from carbon fibre composites incorporating nanomaterials during simultaneous fire and impact","authors":"R. Chapple ,&nbsp;C. Chivas-Joly ,&nbsp;J.-C. Roux ,&nbsp;L. Dumazert ,&nbsp;L. Ferry ,&nbsp;J.-M. Lopez-Cuesta ,&nbsp;E.L. Erskine ,&nbsp;B.K. Kandola","doi":"10.1016/j.impact.2022.100446","DOIUrl":"10.1016/j.impact.2022.100446","url":null,"abstract":"<div><p>This work investigates the aerosols emitted from carbon fibre-reinforced epoxy composites (CFC) incorporating nanomaterials (nanoclays and nanotubes), subjected to simultaneous fire and impact, representing an aeroplane or automotive crash. Simultaneous fire and impact tests were performed using a previously described bespoke testing methodology with the capability to collect particles released from the front/back faces of the impacted composites plus the effluents. In this work the methodology has been further developed by connecting the Dekati Low Pressure Impactor (DLPI) and Mini Particle Sampler (MPS) sampling system in the extraction chimney. The aerosols emitted have been characterized using various devices devoted to the analysis of aerosols. The influence of the nanoadditives in the matrix on the number concentration and the size distribution of airborne particles produced, was studied with a cascade impactor in the 5 nm–10 μm range. The morphology of the separated soot fractions was examined by SEM. The measurement of aerodynamic size of particles that can deposit in human respiratory tract indicate that 75% of the soot and particles released from CFC could deposit in the lungs reaching the bronchi region at a minimum. There was however, a minimal difference between the number particle concentrations or particle-size mass distribution of particles from CFC and CFC containing nanoadditives. Moreover, no fibres were found in the effluents.</p></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9667014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Selenium nanomaterials improve the quality of lettuce (Lactuca sativa L.) by modulating root growth, nutrient availability, and photosynthesis 硒纳米材料通过调节根系生长、养分有效性和光合作用来提高莴苣的质量
IF 4.9 3区 环境科学与生态学
NanoImpact Pub Date : 2023-01-01 DOI: 10.1016/j.impact.2022.100449
Bingxu Cheng , Chuanxi Wang , Le Yue , Feiran Chen , Xuesong Cao , Qianqian Lan , Tianxi Liu , Zhenyu Wang
{"title":"Selenium nanomaterials improve the quality of lettuce (Lactuca sativa L.) by modulating root growth, nutrient availability, and photosynthesis","authors":"Bingxu Cheng ,&nbsp;Chuanxi Wang ,&nbsp;Le Yue ,&nbsp;Feiran Chen ,&nbsp;Xuesong Cao ,&nbsp;Qianqian Lan ,&nbsp;Tianxi Liu ,&nbsp;Zhenyu Wang","doi":"10.1016/j.impact.2022.100449","DOIUrl":"10.1016/j.impact.2022.100449","url":null,"abstract":"<div><p>Macro- or micro-nutrients are essential for crop yield and nutritional quality. In this work, selenium engineering nanomaterials (Se ENMs, 0.5 mg‧kg<sup>−1</sup>) significantly increased the yield and nutritional quality of lettuce, which was better than that of selenite (Na<sub>2</sub>SeO<sub>3</sub>). Under the treatment of Se ENMs, macro-nutrients including nitrogen (N), phosphorus (P), potassium (K), calcium (Ca), and magnesium (Mg) were increased by 15.8%, 98.5%, 42.8%, 146.9%, and 62.5%, respectively, and micro-nutrients including manganese (Mn), iron (Fe), copper (Cu), and zinc (Zn) were also increased by 87.4%, 78.0%, 61.1%, and 56.1%, respectively. As a result, the improved nutritional status of lettuce leaves increased photosynthesis (59.2%) and yield (37.6%). Root diameters and root tips of lettuce were increased by 23.9% and 18.6%, respectively, upon exposure to Se ENMs, which may be responsible for facilitating the absorption of macro and micro nutrients from the soil. These effects were significantly better than SeO<sub>3</sub><sup>2−</sup> treated group. Metabolome results indicated that Se ENMs could improve the shikimic acid, phenylalanine, and tyrosine pathway, resulting in an enhancement of the beneficial compounds, including quercetin, rutin, and coumarin, by 2.9, 2.7, and 2.4-fold, respectively. Besides, pyruvic acid and TCA cycle were also improved by Se ENMs. These results provide new insight into the positive effect of Se ENMs on crop yield and nutritional quality, which demonstrate that the Se ENMs-enabled agriculture practices have a promising prospect as a sustainable crop strategy.</p></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9366843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Gene expression profiling of human macrophages after graphene oxide and graphene nanoplatelets treatment reveals particle-specific regulation of pathways 氧化石墨烯和石墨烯纳米片处理后人类巨噬细胞的基因表达谱揭示了颗粒特异性通路调控
IF 4.9 3区 环境科学与生态学
NanoImpact Pub Date : 2023-01-01 DOI: 10.1016/j.impact.2023.100452
Daria Korejwo , Savvina Chortarea , Chrysovalanto Louka , Marija Buljan , Barbara Rothen-Rutishauser , Peter Wick , Tina Buerki-Thurnherr
{"title":"Gene expression profiling of human macrophages after graphene oxide and graphene nanoplatelets treatment reveals particle-specific regulation of pathways","authors":"Daria Korejwo ,&nbsp;Savvina Chortarea ,&nbsp;Chrysovalanto Louka ,&nbsp;Marija Buljan ,&nbsp;Barbara Rothen-Rutishauser ,&nbsp;Peter Wick ,&nbsp;Tina Buerki-Thurnherr","doi":"10.1016/j.impact.2023.100452","DOIUrl":"10.1016/j.impact.2023.100452","url":null,"abstract":"<div><p>Graphene and its derivatives are attractive materials envisaged to enable a wealth of novel applications in many fields including energy, electronics, composite materials or health. A comprehensive understanding of the potential adverse effects of graphene-related materials (GRM) in humans is a prerequisite to the safe use of these promising materials. Here, we exploited gene expression profiling to identify transcriptional responses and toxicity pathways induced by graphene oxide (GO) and graphene nanoplatelets (GNP) in human macrophages. Primary human monocyte-derived macrophages (MDM) and a human macrophage cell line, i.e. differentiated THP-1 cells, were exposed to 5 or 20 μg/mL GO and GNP for 6 and 24 h to capture early and more persistent acute responses at realistic or slightly overdose concentrations. GO and GNP induced time-, dose- and macrophage type-specific differential expression of a substantial number of genes with some overlap between the two GRM types (up to 384 genes (9.6%) or 447 genes (20.4%) in THP-1 or MDM, respectively) but also a high number of genes exclusively deregulated from each material type. Furthermore, GRM responses on gene expression were highly different from those induced by inflammogenic material crystalline quartz (maximum of 64 (2.3%) or 318 (11.3%) common genes for MDM treated with 20 μg/mL GO and GNP, respectively). Further bioinformatics analysis revealed that GNP predominantly activated genes controlling inflammatory and apoptotic pathways whereas GO showed only limited inflammatory responses. Interestingly, both GRM affected the expression of genes related to antigen processing and presentation and in addition, GO activated pathways of neutrophil activation, degranulation and immunity in MDM. Overall, this study provides an extensive resource of potential toxicity mechanisms for future safety assessment of GRM in more advanced model systems to verify if the observed changes in gene expression in human macrophages could lead to long-term consequences on human health.</p></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9305426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Applicability of OECD TG 201, 202, 203 for the aquatic toxicity testing and assessment of 2D Graphene material nanoforms to meet regulatory needs OECD TG 201、202、203适用于2D石墨烯材料纳米形式的水生毒性测试和评估,以满足监管需求
IF 4.9 3区 环境科学与生态学
NanoImpact Pub Date : 2023-01-01 DOI: 10.1016/j.impact.2022.100447
M. Connolly , G. Moles , F. Candotto Carniel , M. Tretiach , G. Caorsi , E. Flahaut , B. Soula , E. Pinelli , L. Gauthier , F. Mouchet , J.M. Navas
{"title":"Applicability of OECD TG 201, 202, 203 for the aquatic toxicity testing and assessment of 2D Graphene material nanoforms to meet regulatory needs","authors":"M. Connolly ,&nbsp;G. Moles ,&nbsp;F. Candotto Carniel ,&nbsp;M. Tretiach ,&nbsp;G. Caorsi ,&nbsp;E. Flahaut ,&nbsp;B. Soula ,&nbsp;E. Pinelli ,&nbsp;L. Gauthier ,&nbsp;F. Mouchet ,&nbsp;J.M. Navas","doi":"10.1016/j.impact.2022.100447","DOIUrl":"10.1016/j.impact.2022.100447","url":null,"abstract":"<div><p>Tests using algae and/or cyanobacteria, invertebrates (crustaceans) and fish form the basic elements of an ecotoxicological assessment in a number of regulations, in particular for classification of a substance as hazardous or not to the aquatic environment according to the Globally Harmonised System of Classification and Labelling of Chemicals (GHS-CLP) (<span>GHS, 2022</span>) and the REACH regulation (Registration, Evaluation, Authorisation and Restriction of Chemicals, <span>EC, 2006</span>). Standardised test guidelines (TGs) of the Organisation for Economic Co-operation and Development (OECD) are available to address the regulatory relevant endpoints of growth inhibition in algae and cyanobacteria (TG 201), acute toxicity to invertebrates (TG 202), and acute toxicity in fish (TG 203). Applying these existing OECD TGs for testing two dimensional (2D) graphene nanoforms may require more attention, additional considerations and/or adaptations of the protocols, because graphene materials are often problematic to test due to their unique attributes. In this review a critical analysis of all existing studies and approaches to testing used has been performed in order to comment on the current state of the science on testing and the overall ecotoxicity of 2D graphene materials. Focusing on the specific tests and available guidance's, a complete evaluation of aquatic toxicity testing for hazard classification of 2D graphene materials, as well as the use of alternative tests in an integrated approach to testing and assessment, has been made. This information is essential to ensure future assessments generate meaningful data that will fulfil regulatory requirements for the safe use of this “wonder” material.</p></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9366824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effects of industrially produced 2-dimensional molybdenum disulfide materials in primary human basophils 工业生产的二维二硫化钼材料对原代人类嗜碱性粒细胞的影响
IF 4.9 3区 环境科学与生态学
NanoImpact Pub Date : 2023-01-01 DOI: 10.1016/j.impact.2023.100451
Hazel Lin , Antonio Esau del Rio Castillo , Viviana Jehová González , Lucas Jacquemin , Jaya Kumar Panda , Francesco Bonaccorso , Ester Vázquez , Alberto Bianco
{"title":"Effects of industrially produced 2-dimensional molybdenum disulfide materials in primary human basophils","authors":"Hazel Lin ,&nbsp;Antonio Esau del Rio Castillo ,&nbsp;Viviana Jehová González ,&nbsp;Lucas Jacquemin ,&nbsp;Jaya Kumar Panda ,&nbsp;Francesco Bonaccorso ,&nbsp;Ester Vázquez ,&nbsp;Alberto Bianco","doi":"10.1016/j.impact.2023.100451","DOIUrl":"10.1016/j.impact.2023.100451","url":null,"abstract":"<div><p>MoS<sub>2</sub> has been increasingly used in place of graphene as a flexible and multifunctional 2D material in many biomedical applications such as cancer detection and drug delivery, which makes it crucial to evaluate downstream compatibility in human immune cells. Molybdenum is a component of stainless-steel stent implants and has previously been implicated in stent hypersensitivity. In view of this, it is important to ascertain the effect of MoS<sub>2</sub> on allergy-relevant cells. Basophils are a less commonly used immune cell type. Unlike mast cells, basophils can be easily derived from primary human blood and can act as a sentinel for allergy. However, merely testing any one type of MoS<sub>2</sub> in basophils could result in different biological results. We thus decided to compare 2D MoS<sub>2</sub> from the two companies BeDimensional© (BD) and Biograph Solutions (BS), manufactured with two different but commonly exploited methods (BD, deoxycholate surfactant in a high-pressure liquid exfoliation, and BS using glycine in ball-milling exfoliation) to elucidate immunological end-points common to both MoS<sub>2</sub> and to demonstrate the need for biological verification for end-users who may require a change of supplier. We report higher histamine production in human basophils with MoS<sub>2</sub>. No effects on either surface basophil activation markers CD63 and CD203c or reactive oxygen species (ROS) production and cell viability were observed. However, different cytokine production patterns were evidenced. IL-6 and IL-1β but not TNF and GM-CSF were increased for both MoS<sub>2</sub>. BS-MoS<sub>2</sub> increased IL-4, while BD-MoS<sub>2</sub> decreased IL-4 and increased IL-13. Molybdate ion itself only increased IL-1β and IL-4. Deoxycholate surfactant decreased viability at 18 h and increased ROS upon basophil activation. Therefore, these results demonstrate the safety of MoS<sub>2</sub> in human basophils in general and highlight the importance of considering manufacturer additives and variability when selecting and investigating 2D materials such as MoS<sub>2</sub>.</p></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9681708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Silica nanoparticles activate defense responses by reducing reactive oxygen species under Ralstonia solanacearum infection in tomato plants 二氧化硅纳米粒子通过减少活性氧来激活番茄植株在茄枯菌侵染下的防御反应
IF 4.9 3区 环境科学与生态学
NanoImpact Pub Date : 2022-10-01 DOI: 10.1016/j.impact.2022.100418
Lei Wang , Taowen Pan , Xuhua Gao , Jing An , Chuanchuan Ning , Sicong Li , Kunzheng Cai
{"title":"Silica nanoparticles activate defense responses by reducing reactive oxygen species under Ralstonia solanacearum infection in tomato plants","authors":"Lei Wang ,&nbsp;Taowen Pan ,&nbsp;Xuhua Gao ,&nbsp;Jing An ,&nbsp;Chuanchuan Ning ,&nbsp;Sicong Li ,&nbsp;Kunzheng Cai","doi":"10.1016/j.impact.2022.100418","DOIUrl":"10.1016/j.impact.2022.100418","url":null,"abstract":"<div><p><span><span><span>Silica nanoparticles (SNPs) play an important positive role in enhancing stress resistance of plants. However, their absorption and the mechanisms of resistance in plants are not yet fully understood. In this study, we investigated the uptake of SNPs in tomato plants and explored the physiological and molecular mechanisms of SNPs-mediated </span>bacterial wilt resistance. Folia application of SNPs significantly increased silicon content in tomato leaves and roots by 5.4-fold and 1.8-fold compared with healthy control, respectively. Moreover, foliar-applied SNPs mainly accumulated in the shoots of plants. Interestingly, we found that SNPs significantly reduced wilt severity by 20.71%–87.97%. Under </span>pathogen infection conditions, the Hydrogen peroxide (H</span><sub>2</sub>O<sub>2</sub><span><span>) levels and Malondialdehyde (MDA) content in SNPs treated leaves significantly decreased by 16.33%–24.84% and 22.15%–38.54%, respectively, compared to non-treated SNPs leaves. The application of SNPs remarkably increased </span>peroxidase<span><span> (78.56–157.47%), superoxide dismutase (46.02–51.68%), and </span>catalase<span> (1.59–1.64 fold) enzyme activities, as well as upregulated the expression of salicylic acid-related genes (</span></span></span><em>PR-1</em>, <em>PR-5</em>, and <em>PAL</em><span><span>) in tomato leaves. Taken together, our findings demonstrate that SNPs function as important nanoparticles to maintain ROS </span>homeostasis in plants by increasing antioxidant enzyme activity in tomato plants and enhancing plant tolerance to bacterial wilt disease by regulating the expression of salicylic acid-related genes. This study expands our understanding of how plants utilize these nanoparticles to deal with pathogen infection.</span></p></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10445765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Editorial to special issue on “Nano-enabled approaches for sustainable development of food and agricultural systems” “粮食和农业系统可持续发展的纳米方法”特刊社论
IF 4.9 3区 环境科学与生态学
NanoImpact Pub Date : 2022-10-01 DOI: 10.1016/j.impact.2022.100434
Muhammad Adeel , Muhammad Arslan Ahmad , Melanie Kah , Leonardo Fraceto , Jason C. White
{"title":"Editorial to special issue on “Nano-enabled approaches for sustainable development of food and agricultural systems”","authors":"Muhammad Adeel ,&nbsp;Muhammad Arslan Ahmad ,&nbsp;Melanie Kah ,&nbsp;Leonardo Fraceto ,&nbsp;Jason C. White","doi":"10.1016/j.impact.2022.100434","DOIUrl":"10.1016/j.impact.2022.100434","url":null,"abstract":"","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10448065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Nanogold morphologies with the same surface chemistry provoke a different innate immune response: An in-vitro and in-vivo study 具有相同表面化学的纳米金形态引起不同的先天免疫反应:一项体外和体内研究
IF 4.9 3区 环境科学与生态学
NanoImpact Pub Date : 2022-10-01 DOI: 10.1016/j.impact.2022.100419
Muhammad Usman , Yasra Sarwar , Rashda Abbasi , Hafiz Muhammad Ishaq , Maryam Iftikhar , Irshad Hussain , Ruken Esra Demirdogen , Ayesha Ihsan
{"title":"Nanogold morphologies with the same surface chemistry provoke a different innate immune response: An in-vitro and in-vivo study","authors":"Muhammad Usman ,&nbsp;Yasra Sarwar ,&nbsp;Rashda Abbasi ,&nbsp;Hafiz Muhammad Ishaq ,&nbsp;Maryam Iftikhar ,&nbsp;Irshad Hussain ,&nbsp;Ruken Esra Demirdogen ,&nbsp;Ayesha Ihsan","doi":"10.1016/j.impact.2022.100419","DOIUrl":"10.1016/j.impact.2022.100419","url":null,"abstract":"<div><p><span><span><span>Gold nanomaterials (GNMs) have unique </span>optical properties with less antigenicity, and their </span>physicochemical properties have strong relation with an immunological response at bio-interface including antigenicity. An interpretation of this correlation would significantly impact on the clinical and theranostic applications of GNMs. Herein, we studied the effect of GNMs morphology on the cytotoxicity (</span><em>in-vitro</em><span>), innate immune responses, hepatotoxicity, and nephrotoxicity (</span><em>in-vivo</em><span> studies) using gold nano-cups (GNCs), porous gold nanospheres<span> (PGNSs) and solid gold nano particles (SGNPs) coated with the same ligand to ensure similar surface chemistry. The cytotoxicity was assessed </span></span><em>via</em><span> sulfo-rhodamine B (SRB) assay, and the cytotoxicity data showed that morphological features at nanoscale dimensions like surface roughness and hollowness </span><em>etc.</em> have a significant impact on cellular viability. The biochemical and histopathological study of liver and kidney tissues also showed that all GNMs did not show any toxicity even at high concentration (100 μL). The relative quantification of cytokine gene expression of TNF-α, IFN-γ, IL-4, 1L-6, and 1L-17 (against each morphology) was checked after <em>in-vivo</em><span> activation in mice. Among the different nanogold morphologies, PVP<span> stabilized GNCs (PVP-GNCs) showed the highest release of pro-inflammatory cytokines, which might be due to their high surface energy and large surface area for exposure as compared to other nanogold morphologies studied. The pro-inflammatory cytokine release could be suppressed by coating with some anti-inflammatory polymer, </span></span><em>i.e.</em><span>, inulin</span><em>.</em> The <em>in-vitro</em> results of pro-inflammatory (TNF-α, IL-1) cytokines also suggested that all GNMs may induce activation of macrophages and Th1 immune response. The <em>in-vivo</em> activation results showed a decrease in mRNA expression of the cytokines (TNF-α, IFN-γ, IL-4, 1L-6 and 1L-17). Based on these findings, we proposed that the shape and morphology of GNMs control their immune response at nano-bio interface, and it must be considered while designing their role for different biomedical applications like immuno-stimulation and bio-imaging.</p></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10813184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Combined application of biochar and nano-zeolite enhanced cadmium immobilization and promote the growth of Pak Choi in cadmium contaminated soil 生物炭与纳米沸石复合施用增强了镉的固定化作用,促进了白菜在镉污染土壤中的生长
IF 4.9 3区 环境科学与生态学
NanoImpact Pub Date : 2022-10-01 DOI: 10.1016/j.impact.2022.100421
Shanshan Feng , Peng Zhang , Yanmei Hu , Feng Jin , Yuqing Liu , Shixin Cai , Zijie Song , Xing Zhang , Tcyganova Nadezhda , Zhiling Guo , Iseult Lynch , Xiuli Dang
{"title":"Combined application of biochar and nano-zeolite enhanced cadmium immobilization and promote the growth of Pak Choi in cadmium contaminated soil","authors":"Shanshan Feng ,&nbsp;Peng Zhang ,&nbsp;Yanmei Hu ,&nbsp;Feng Jin ,&nbsp;Yuqing Liu ,&nbsp;Shixin Cai ,&nbsp;Zijie Song ,&nbsp;Xing Zhang ,&nbsp;Tcyganova Nadezhda ,&nbsp;Zhiling Guo ,&nbsp;Iseult Lynch ,&nbsp;Xiuli Dang","doi":"10.1016/j.impact.2022.100421","DOIUrl":"10.1016/j.impact.2022.100421","url":null,"abstract":"<div><p><span>Biochar and zeolite have been demonstrated effective to remove heavy metals in soil; however, the effect of combined application of the both materials on the fraction of Cd and soil-plant system are largely unknown. Cd fractions in soil, growth and Cd uptake of Pak Choi were measured after the combined application of biochar (0, 5, 10 and 20 g·kg</span><sup>−1</sup>) and nano-zeolite (0, 5, 10, 20 g·kg<sup>−1</sup>) by pot experiment. Results showed that both single and combined application reduced the exchangeable Cd in soil and improved the plant growth. However, combined application of 20 g·kg<sup>−1</sup> biochar with 10 g·kg<sup>−1</sup> nano-zeolite showed the strongest effect, with the residual Cd in soil increased by 214% as compared with control. 20 g·kg<sup>−1</sup> biochar with 10 g·kg<sup>−1</sup><span><span><span> nano-zeolite Mechanic studies showed that this combination enhanced the antioxidant system, with the SOD, </span>CAT and </span>POD activities<span><span> enhanced by 56.1%, 133.3% and 235.3%, respectively. The oxidative stress was reduced correspondingly, as shown by the reduced </span>MDA<span><span> contents (by 46.7%). This combination also showed the best efficiency in regulating soil pH, organic matter and soil enzymes thus improving the plant growth. This study suggests that combined application various materials such as biochar and nano-zeolite may provide new strategies for reducing the bioavailability of Cd in soil and thus the accumulation in </span>edible plants.</span></span></span></p></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10436846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
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