NanoImpact最新文献

{"title":"Elemental carbon - An efficient method to measure occupational exposure from materials in the graphene family","authors":"Tobias Storsjö ,&nbsp;Håkan Tinnerberg ,&nbsp;Jinhua Sun ,&nbsp;Chen Ruiqi ,&nbsp;Anne Farbrot","doi":"10.1016/j.impact.2024.100499","DOIUrl":"10.1016/j.impact.2024.100499","url":null,"abstract":"<div><p>Graphene is a 2D-material with many useful properties such as flexibility, elasticity, and conductivity among others. Graphene could therefore become a material used in many occupational fields in the future, which can give rise to occupational exposure. Today, exposure is unknown, due to the lack of efficient measuring techniques for occupational exposure to graphene. Readily available screening techniques for air sampling and -analysis are either nonspecific or nonquantitative. Quantifying materials from the broad graphene family by an easy-to-use method is important for the large-scale industrial application of graphene, especially when for the safety of working environment. Graphene consists primarily of elemental carbon, and the present study evaluates the organic carbon/elemental carbon (OC/EC)-technique for exposure assessment. The purpose of this work is to evaluate the OC/EC analysis technique as an efficient and easy-to-use method for quantification of occupational exposure to graphene. Methods that can identify graphene would be preferable for screening, but they are time consuming and semi-quantitative and therefore not suited for quantitative work environment assessments. The OC/EC-technique is a thermal optical analysis (TOA), that quantitively determines the amount of and distinguishes between two different types of carbon, organic and elemental. The technique is standardised, well-established and among other things used for diesel exposure measurements (ref standard). OC/EC could therefore be a feasible measuring technique to quantitively determine occupational exposure to graphene. The present evaluation of the technique provides an analytical method that works quantitatively for graphene, graphene oxide and reduced graphene oxide. Interestingly, the TOA technique makes it possible to distinguish between the three graphene forms used in this study. The technique was tested in an industrial setting and the outcome suggests that the technique is an efficient monitoring technique to be used in combination with characterisation techniques like for example Raman spectroscopy, scanning electron microscopy and atomic force microscopy.</p></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"33 ","pages":"Article 100499"},"PeriodicalIF":4.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139900153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protein corona exacerbated inflammatory response in macrophages elicited by CdTe quantum dots","authors":"Na Liu ,&nbsp;Ying Liang ,&nbsp;Tingting Wei ,&nbsp;Xiaoquan Huang ,&nbsp;Ting Zhang ,&nbsp;Meng Tang","doi":"10.1016/j.impact.2024.100494","DOIUrl":"10.1016/j.impact.2024.100494","url":null,"abstract":"<div><p><span>Nano-bio interface is significant concern in nanomedicine<span>. When nanoparticles (NPs) come into contact with cells, they form complexes with proteins known as </span></span>protein corona<span><span> (PC). Cadmium telluride </span>quantum dots<span><span> (CdTe QDs) have been applied as bioimaging probes and for macrophage theragnostic. However, the impact of protein corona on the behavior of CdTe QDs is not well understood. Macrophages play a crucial role in defending against NPs. In this study, RAW264.7 cells were used to investigated the inflammatory response in macrophages when exposed to CdTe QDs before and after PC formation in fetal bovine serum. The results indicated that protein corona polarized more macrophages towards M1 phenotype. Transcriptomics analysis revealed that PC-CdTe QDs altered a greater number of differentially expressed genes (DEGs) compared to CdTe QDs (177 and 398) at 1.0 μM in macrophages. The DEGs affected by PC-CdTe QDs contained several personalized inflammatory cytokines. The enriched pathways after PC formation included Cytokine-cytokine receptor interaction, NOD-like receptor signaling pathway, and TNF signaling pathway, etc. Furthermore, PC specifically exacerbated the overexpression of CCL2 and IL-1β proteins. Importantly, PC altered the mechanism of CdTe QD-induced pyroptosis, shifting it from activating NLRC4 to both NLRP1 and NLRP3 </span>inflammasomes, and from cleaving GSDMD and GSDMB to GSDMB alone. Overall, protein corona exacerbated the inflammatory response induced by CdTe QDs in macrophages. This study provides valuable insight into the pro-inflammatory effect of protein corona on CdTe QDs, with implications for their use in bioimaging or macrophage theragnostic by either exploiting or eliminating this biological interface effect.</span></span></p></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"33 ","pages":"Article 100494"},"PeriodicalIF":4.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139500590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toxic effects of environmental-relevant exposure to polyethylene terephthalate (PET) micro and nanoparticles in zebrafish early development","authors":"Lilian de Souza Teodoro ,&nbsp;Camilo Alexandre Jablonski ,&nbsp;Kauê Pelegrini ,&nbsp;Talita Carneiro Brandão Pereira ,&nbsp;Thuany Garcia Maraschin ,&nbsp;Alan Carvalho de Sousa Araujo ,&nbsp;Jose Maria Monserrat ,&nbsp;Nara Regina de Souza Basso ,&nbsp;Luiza Wilges Kist ,&nbsp;Maurício Reis Bogo","doi":"10.1016/j.impact.2024.100497","DOIUrl":"10.1016/j.impact.2024.100497","url":null,"abstract":"<div><p>Polyethylene terephthalate (PET) is a commonly used thermoplastic in industry due to its excellent malleability and thermal stability, making it extensively employed in packaging manufacturing. Inadequate disposal of PET packaging in the environment and natural physical-chemical processes leads to the formation of smaller particles known as PET micro and nanoplastics (MNPs). The reduced dimensions enhance particle bioavailability and, subsequently, their reactivity. This study involved chemical degradation of PET using trifluoroacetic acid to assess the impact of exposure to varying concentrations of PET MNPs (0.5, 1, 5, 10, and 20 mg/L) on morphological, functional, behavioral, and biochemical parameters during the early developmental stages of zebrafish (<em>Danio rerio</em>). Characterization of the degraded PET revealed the generated microplastics (MPs) ranged in size from 1305 to 2032 μm, and that the generated nanoplastics (NPs) ranged from 68.06 to 955 nm. These particles were then used for animal exposure. After a six-day exposure period, our findings indicate that PET MNPs can diminish spontaneous tail coiling (STC), elevate the heart rate, accumulate on the chorion surface, and reduce interocular distance. These results suggest that PET exposure induces primary toxic effects on zebrafish embryo-larval stage of development.</p></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"33 ","pages":"Article 100497"},"PeriodicalIF":4.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139679285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanoscale sulfur alters the bacterial and eukaryotic communities of the tomato rhizosphere and their interactions with a fungal pathogen","authors":"Blaire Steven ,&nbsp;M. Amine Hassani ,&nbsp;Jacquelyn C. LaReau ,&nbsp;Yi Wang ,&nbsp;Jason C. White","doi":"10.1016/j.impact.2024.100495","DOIUrl":"10.1016/j.impact.2024.100495","url":null,"abstract":"<div><p><span>Nanoformulations of sulfur have demonstrated the potential to enhance plant growth and reduce disease incidence when plants are confronted with pathogens<span><span>. However, the impact of nanoscale sulfur on microbial communities in close contact with the plant root, known as the rhizosphere, remain poorly characterized. In this study, we investigate the impact of three formulations of sulfur; bulk sulfur, uncoated (pristine) sulfur </span>nanoparticles<span>, and stearic acid coated sulfur nanoparticles, on the rhizosphere of tomato plants. Tomato plants were additionally challenged by the pathogenic fungus </span></span></span><span><em>Fusarium oxysporum</em><em> f.</em></span> sp. <em>Lycopersici</em><span><span>. Employing bacterial 16S rRNA gene sequencing, along with recently in-house designed </span>peptide nucleic acid<span> clamps to facilitate the recovery of microeukaryote sequences, we performed a comprehensive survey of rhizosphere microbial populations. We found the largest influence on the composition of the rhizosphere microbiome<span> was the presence of the fungal pathogen. However, sulfur amendments also drove state changes in the rhizosphere populations; for example, enriching the relative abundance of the plant-beneficial sulfur-oxidizing bacterium </span></span></span><span><em>Thiobacillus</em></span>. Notably, when investigating the response of the rhizosphere community to the different sulfur amendments, there was a strong interaction between the fungal pathogen and sulfur treatments. This resulted in different bacterial and eukaryotic taxa being enriched in association with the different forms of sulfur, which was dependent on the presence of the pathogen. These data point to nano formulations of sulfur exerting unique shifts in the rhizosphere community compared to bulk sulfur, particularly in association with a plant pathogen, and have implications for the sustainable use of nanoscale strategies in sustainable agriculture.</p></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"33 ","pages":"Article 100495"},"PeriodicalIF":4.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139500676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stool titanium dioxide is positively associated with stool alpha-1 antitrypsin and calprotectin in young healthy adults","authors":"Christianto Putra,&nbsp;Dhimiter Bello,&nbsp;Shannon L. Kelleher,&nbsp;Katherine L. Tucker,&nbsp;Kelsey M. Mangano","doi":"10.1016/j.impact.2024.100498","DOIUrl":"10.1016/j.impact.2024.100498","url":null,"abstract":"<div><p>Titanium dioxide (TiO2/E171) is used widely in foods, primarily as a food additive. Animal models have shown that chronic TiO₂ exposure may disturb homeostasis of the gastrointestinal tract by increasing gut permeability, inducing gut inflammation, and increasing the likelihood of microbial infection. Adults have a wide range of ingested TiO₂,which span two to three orders of magnitude, with a small portion of individuals consuming near gram quantities of TiO2/day. However, research on the health effects of chronic ingestion of TiO2/E171 in humans is limited. We hypothesized that regularly ingested TiO2/E171 is associated with increased gut inflammation and gut permeability in healthy adults. We tested this hypothesis in a cross-sectional design by measuring clinically established stool markers of gut inflammation (calprotectin, lactoferrin) and gut permeability (alpha-1 antitrypsin; A1AT) in 35 healthy adults, and comparing these markers between relatively high and low TiO2 exposure groups. Participants were stratified by TiO2 stool content (high dry stool TiO2 content: 0.95–9.92 μg/mg, <em>n</em> = 20; low content: 0.01–0.04 μg/mg; <em>n</em> = 15). Differences in gut health markers were tested between high and low exposure groups by independent samples <em>t</em>-test or Mann-Whitney <em>U</em> test. Multivariable linear regression was used to assess the association between TiO2 in dry stool and measured stool alpha-1 antitrypsin (A1AT). Participants in the high stool TiO2 group had greater stool A1AT (42.7 ± 21.6 mg/dL; median: 38.3; range: 1.0–49.2 mg/dL), compared to the low TiO2 group (22.8 ± 13.6 mg/dL; median: 20.9; range: 8.7–93.0 mg/dL), <em>P</em> = 0.003. There was also greater stool calprotectin in the high TiO₂ group (51.4 ± 48.6 μg/g; median 29.2 μg/g; range: 15.3–199.0 μg/g) than in the low group (47.5 ± 63.3 μg/g; median 18.8 μg/g; range: 1.6–198.1 μg/g), <em>P</em> = 0.04. No clear difference was observed for lactoferrin (high TiO2 group 1.6 ± 2.1 μg/g; median: 0.68 μg/g; range: 0.01–7.7 μg/g, low TiO2 group: 1.3 ± 2.6 μg/g; median: 0.2; range: 0.01–7.6 μg/g) (<em>P</em> = 0.15). A1AT concentration was positively associated with stool TiO2, after adjusting for confounders (β ± SE: 19.6 ± 7.2; <em>P</em> = 0.01) R² = 0.38). Community dwelling, healthy adults with the highest TiO2 stool content had higher stool A1AT and calprotectin, compared to those with the lowest TiO₂ stool content. Ongoing research is needed to validate these observations in larger groups, and to determine the long-term effects of ingested TiO₂ on human gut health, using these and additional health endpoints.</p></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"33 ","pages":"Article 100498"},"PeriodicalIF":4.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139876317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eco-corona-mediated transformation of nano-sized Y2O3 in simulated freshwater: A short-term study","authors":"Alexander Khort ,&nbsp;Tingru Chang ,&nbsp;Jing Hua ,&nbsp;Eva Blomberg ,&nbsp;Tommy Cedervall ,&nbsp;Inger Odnevall","doi":"10.1016/j.impact.2023.100490","DOIUrl":"10.1016/j.impact.2023.100490","url":null,"abstract":"<div><p>The use of metal and metal oxide nanomaterials (NMs) is experiencing a significant surge in popularity due to their distinctive structures and properties, making them highly attractive for a wide range of applications. This increases the risks of their potential negative impact on organisms if dispersed into the environment. Information about their behavior and transformation upon environmental interactions in aquatic settings is limited. In this study, the influence of naturally excreted biomolecules from the zooplankton <em>Daphnia magna</em> on nanosized Y₂O₃ of different concentrations was systematically examined in synthetic freshwater in terms of adsorption and eco-corona formation, colloidal stability, transformation, dissolution, and ecotoxicity towards <em>D. magna</em>. The formation of an eco-corona on the surface of the Y₂O₃ NMs leads to improved colloidal stability and a reduced extent of dissolution. Exposure to the Y₂O₃ NMs lowered the survival probability of <em>D. magna</em> considerably. The ecotoxic potency was slightly reduced by the formation of the eco-corona, though shown to be particle concentration-specific. Overall, the results highlight the importance of systematic mechanistic and fundamental studies of factors that can affect the environmental fate and ecotoxic potency of NMs.</p></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"33 ","pages":"Article 100490"},"PeriodicalIF":4.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2452074823000411/pdfft?md5=caf924e5c45c1ca793fea21d13b8bcdf&pid=1-s2.0-S2452074823000411-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139055308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Life-cycle risk assessment of graphene-enabled textiles in fire protection gear","authors":"James D. Ede ,&nbsp;Ana S. Diges ,&nbsp;Yueyang Zhang ,&nbsp;Jo Anne Shatkin","doi":"10.1016/j.impact.2023.100488","DOIUrl":"10.1016/j.impact.2023.100488","url":null,"abstract":"<div><p>A nanomaterial life-cycle risk assessment (Nano LCRA) of a graphene-enabled textile used in the construction of heat and fire-resistant personal protective equipment (PPE) was conducted to develop, analyze, and prioritize potential occupational, health and environmental risks. The analysis identifies potential receptors and exposure pathways at each product life-cycle stage and makes a qualitative evaluation of the potential significance of each scenario. A literature review, quality evaluation, and database were developed as part of the LCRA to identify potential hazards associated with graphene-based materials (GBMs) throughout the product life-cycle. Generally, risks identified from graphene-enabled textiles were low. Of the developed exposure scenarios, occupational inhalation exposures during raw material and product manufacturing ranked highest. The analysis identifies the key potential human and environmental hazards and exposures of the products across the product life-cycle of graphene enabled textiles. Priority research gaps to reduce uncertainty include evaluating long-term, low dose graphene exposures typical of the workplace, as well as the potential release and hazard characterization of graphene-acrylic nanocomposites.</p></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"33 ","pages":"Article 100488"},"PeriodicalIF":4.9,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71522114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Micro- and nanoplastics (MNPs) and their potential toxicological outcomes: State of science, knowledge gaps and research needs","authors":"Zhenning Yang ,&nbsp;Glen M. DeLoid ,&nbsp;Helmut Zarbl ,&nbsp;Joshua Baw ,&nbsp;Philip Demokritou","doi":"10.1016/j.impact.2023.100481","DOIUrl":"10.1016/j.impact.2023.100481","url":null,"abstract":"<div><p>Plastic waste has been produced at a rapidly growing rate over the past several decades. The environmental impacts of plastic waste on marine and terrestrial ecosystems have been recognized for years. Recently, researchers found that micro- and nanoplastics (MNPs), micron (100 nm – 5 mm) and nanometer (1 – 100 nm) scale particles and fibers produced by degradation and fragmentation of plastic waste in the environment, have become an important emerging environmental and food chain contaminant with uncertain consequences for human health. This review provides a comprehensive summary of recent findings from studies of potential toxicity and adverse health impacts of MNPs in terrestrial mammals, including studies in both in vitro cellular and in vivo mammalian models. Also reviewed here are recently released biomonitoring studies that have characterized the bioaccumulation, biodistribution, and excretion of MNPs in humans. The majority MNPs in the environment to which humans are most likely to be exposed, are of irregular shapes, varied sizes, and mixed compositions, and are defined as secondary MNPs. However, the MNPs used in most toxicity studies to date were commercially available primary MNPs of polystyrene (PS), polyethylene (PE), polyvinyl chloride (PVC), polyethylene terephthalate (PET), and other polymers. The emerging in vitro and in vivo evidence reviewed here suggests that MNP toxicity and bioactivity are largely determined by MNP particle physico-chemical characteristics, including size, shape, polymer type, and surface properties. For human exposure, MNPs have been identified in human blood, urine, feces, and placenta, which pose potential health risks. The evidence to date suggests that the mechanisms underlying MNP toxicity at the cellular level are primarily driven by oxidative stress. Nonetheless, large knowledge gaps in our understanding of MNP toxicity and the potential health impacts of MNP exposures still exist and much further study is needed to bridge those gaps. This includes human population exposure studies to determine the environmentally relevant MNP polymers and exposure concentrations and durations for toxicity studies, as well as toxicity studies employing environmentally relevant MNPs, with surface chemistries and other physico-chemical properties consistent with MNP particles in the environment. It is especially important to obtain comprehensive toxicological data for these MNPs to understand the range and extent of potential adverse impacts of microplastic pollutants on humans and other organisms.</p></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"32 ","pages":"Article 100481"},"PeriodicalIF":4.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10338557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extracellular polymeric substances altered the physicochemical properties of molybdenum disulfide nanomaterials to mitigate its toxicity to Chlorella vulgaris","authors":"Manman Cao ,&nbsp;Donghong Yang ,&nbsp;Fei Wang ,&nbsp;Beihai Zhou ,&nbsp;Huilun Chen ,&nbsp;Rongfang Yuan ,&nbsp;Ke Sun","doi":"10.1016/j.impact.2023.100485","DOIUrl":"10.1016/j.impact.2023.100485","url":null,"abstract":"<div><p>Although the toxic effects of two-dimensional nanomaterials (2D-NMs) have been widely reported, the influence of extracellular polymeric substances (EPS) on the environmental fate and risk of 2D-NMs in aquatic environments is largely unknown, and the processes and mechanisms involved remain to be revealed. Herein, we investigated the impact of EPS secreted by microalgae (<em>Chlorella vulgaris</em> (<em>C. vulgaris</em>)) on the environmental transformation and risk of molybdenum disulfide (MoS₂). We found that the attachment of EPS increased the thickness of MoS₂ (from 2 nm to 5 nm), changed it from a monolayer sheet to a fuzzy multilayer structure, and promoted the formation of defects on MoS₂. The blue-shift of the peak associated with the plasmon resonances in the 1 T phase and the generation of electron-hole pairs suggested that EPS altered the surface electronic structure of MoS₂. EPS interacted mainly with the S atoms on the 1 T phase, and the attachment of EPS promoted the oxidation of MoS₂. The reduction in hydrodynamic diameter (<em>D</em>_h) and the decrease in zeta potential indicated that EPS inhibited the agglomeration behavior of MoS₂ and enhanced its dispersion and stability in aqueous media. Notably, EPS reduced the generation of free radicals (superoxide anion (•O₂⁻), singlet oxygen (¹O₂), and hydroxyl radicals (•OH⁻)). Furthermore, EPS mitigated the toxicity of MoS₂ to <em>C. vulgaris</em>, such as attenuated reduction in biomass and chlorophyll content. Compared to pristine MoS₂, MoS₂ + BG11 + EPS exhibited weaker oxidative stress, membrane damage and lipid peroxidation. The adsorption of EPS on MoS₂ surface reduced the attachment sites of MoS₂, making MoS₂ less likely to be enriched on the cell surface. The findings have significant contribution for understanding the interactions between EPS and MoS₂ in aquatic ecosystems, providing scientific guidance for risk assessment of 2D-NMs.</p></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"32 ","pages":"Article 100485"},"PeriodicalIF":4.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41134782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trophic transfer of nanomaterials and their effects on high-trophic-level predators","authors":"Fei Dang ,&nbsp;Yuan Yuan ,&nbsp;Yingnan Huang ,&nbsp;Yujun Wang ,&nbsp;Baoshan Xing","doi":"10.1016/j.impact.2023.100489","DOIUrl":"10.1016/j.impact.2023.100489","url":null,"abstract":"<div><p><span><span>Nanotechnology offers great opportunities for numerous sectors in society. One important challenge in sustainable nanotechnology is the potential of trophic transfer of nanomaterials<span><span> (NMs), which may lead to unintentional impacts on environmental and human health. Here, we highlight the key advances that have been made in recent 15 years with respect to trophic transfer of heterogeneous NMs, including metal-based NMs, carbon-based NMs and nanoplastics, across various aquatic and terrestrial food chains. Particle number-based trophic transfer factors (TTFs), rather than the variable mass-based TTFs, capture the particle-specific transfer, for which NMs exhibit dynamic and complex </span>biotransformation (e.g., dissolution, </span></span>sulfidation, reduction, and corona formation). Trophic transfer of NMs has toxicological significance to predators at molecular (e.g., increased </span>oxidative stress and modified metabolites), physiological (e.g., feeding inhibition) and population (e.g., reproduction inhibition) levels. However, linking NM exposure and toxicity remains a challenge, partly due to the dynamic biotransformation along the food chain. Although NMs have been used to increase crop yield in agriculture, they can exert detrimental impacts on crop yield and modify crop quality, depending on NMs type, exposure dose, and crop species, with unknown consequences to human health via crop consumption. Given this information, we describe the challenges and opportunities in understanding the significance of NMs trophic transfer to develop more sustainable, effective and safer nanotechnology.</p></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"32 ","pages":"Article 100489"},"PeriodicalIF":4.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138295540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}