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Metabolism: clinical and experimental最新文献

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Performance of Established and Novel Non-invasive Tests, Including New Clinical and Metabolomics-Based Machine Learning Models, for Detecting MASH with Fibrosis Stages F2-F3: A First-in-Class Approach in the post-Resmetirom approval era 已建立的和新颖的无创测试的性能，包括新的临床和基于代谢组学的机器学习模型，用于检测F2-F3期纤维化的MASH: remetirom批准后时代的一流方法
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156206
Konstantinos Stefanakis , Geltrude Mingrone , Jacob George , Christos S. Mantzoros
{"title":"Performance of Established and Novel Non-invasive Tests, Including New Clinical and Metabolomics-Based Machine Learning Models, for Detecting MASH with Fibrosis Stages F2-F3: A First-in-Class Approach in the post-Resmetirom approval era","authors":"Konstantinos Stefanakis , Geltrude Mingrone , Jacob George , Christos S. Mantzoros","doi":"10.1016/j.metabol.2025.156206","DOIUrl":"10.1016/j.metabol.2025.156206","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156206"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inherited Stress Vulnerability Exacerbates Obesity-induced Metabolic Alterations Through Dysfunctional Adipose Tissue 遗传性应激易感性通过功能失调的脂肪组织加剧肥胖诱导的代谢改变
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156207
Saumya Kishor Mehta, Michaella Ben-Shachar, Albert Pinhasov, Tovit Rosenzweig
{"title":"Inherited Stress Vulnerability Exacerbates Obesity-induced Metabolic Alterations Through Dysfunctional Adipose Tissue","authors":"Saumya Kishor Mehta, Michaella Ben-Shachar, Albert Pinhasov, Tovit Rosenzweig","doi":"10.1016/j.metabol.2025.156207","DOIUrl":"10.1016/j.metabol.2025.156207","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156207"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation of Insulin Resistance, Type 2 Diabetes Mellitus, Obesity, and Colorectal Cancer Occurrence 胰岛素抵抗、2型糖尿病、肥胖与结直肠癌发生的相关性
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156198
Chong-Chi Chiu , Chao-Ming Hung
{"title":"Correlation of Insulin Resistance, Type 2 Diabetes Mellitus, Obesity, and Colorectal Cancer Occurrence","authors":"Chong-Chi Chiu , Chao-Ming Hung","doi":"10.1016/j.metabol.2025.156198","DOIUrl":"10.1016/j.metabol.2025.156198","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156198"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing Biomarkers of Metabolic Inflammation: The Predictive Accuracy of Plasma Water T2 Exceeds That of High-Sensitivity C-Reactive Protein and Erythrocyte Sedimentation Rate 比较代谢性炎症的生物标志物：血浆水T2的预测准确性超过高敏c反应蛋白和红细胞沉降率
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156210
David P. Cistola , Alok K. Dwivedi
{"title":"Comparing Biomarkers of Metabolic Inflammation: The Predictive Accuracy of Plasma Water T2 Exceeds That of High-Sensitivity C-Reactive Protein and Erythrocyte Sedimentation Rate","authors":"David P. Cistola , Alok K. Dwivedi","doi":"10.1016/j.metabol.2025.156210","DOIUrl":"10.1016/j.metabol.2025.156210","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156210"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring Targeting Inflammasome Signaling: Ginsana-115 as Prime Driver in Insulin Resistance/ cardiovascular Risk (CVD) in Prototypal Brain Disorder: Schizophrenia 探索靶向炎性小体信号：Ginsana-115作为原型脑疾病：精神分裂症中胰岛素抵抗/心血管风险（CVD）的主要驱动因素
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156216
Autumn Carriere, Simon S. Chiu, Michel Woodbury, Mariwan Husni, John Copen, Allison Foskett, Ed Lui, Robbie Campbell
{"title":"Exploring Targeting Inflammasome Signaling: Ginsana-115 as Prime Driver in Insulin Resistance/ cardiovascular Risk (CVD) in Prototypal Brain Disorder: Schizophrenia","authors":"Autumn Carriere, Simon S. Chiu, Michel Woodbury, Mariwan Husni, John Copen, Allison Foskett, Ed Lui, Robbie Campbell","doi":"10.1016/j.metabol.2025.156216","DOIUrl":"10.1016/j.metabol.2025.156216","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156216"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Phase 3, Multicenter, Randomized, Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of Avexitide in Post-Bariatric Hypoglycemia (LUCIDITY) 一项3期、多中心、随机、双盲安慰剂对照研究评估阿维肽治疗减肥后低血糖的疗效和安全性
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156220
Ryan Miller , Marilyn Tan , Tracey McLaughlin , Mary Elizabeth Patti , Suzanne Bijl , Jennifer Hardy , Jorgji Kerthi , Jamie Timmons , Yuehui Wu , Zhengyu Yang , Lahar Mehta , Colleen Craig
{"title":"A Phase 3, Multicenter, Randomized, Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of Avexitide in Post-Bariatric Hypoglycemia (LUCIDITY)","authors":"Ryan Miller , Marilyn Tan , Tracey McLaughlin , Mary Elizabeth Patti , Suzanne Bijl , Jennifer Hardy , Jorgji Kerthi , Jamie Timmons , Yuehui Wu , Zhengyu Yang , Lahar Mehta , Colleen Craig","doi":"10.1016/j.metabol.2025.156220","DOIUrl":"10.1016/j.metabol.2025.156220","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156220"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Hypercortisolism in Patients with Difficult-to-Control Type 2 Diabetes and High Blood Pressure: Results from CATALYST 高皮质醇血症在难以控制的2型糖尿病和高血压患者中的患病率：来自CATALYST的结果
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156214
Yehuda Handelsman , Vanita R. Aroda , Timothy Bailey , Robert S. Busch , John B. Buse , Elena Christofides , Ralph A. DeFronzo , Bradley Eilerman , Vivian Fonseca , Adline Ghazi , Steven E. Kahn , Mark Kipnes , Dan Lender , Jonathan G. Ownby , Jean Park , Julio Rosenstock , Michael Shanik , Lance Sloan , Ron Swerdloff , Guillermo Umpierrez , Daniel Einhorn
{"title":"Prevalence of Hypercortisolism in Patients with Difficult-to-Control Type 2 Diabetes and High Blood Pressure: Results from CATALYST","authors":"Yehuda Handelsman , Vanita R. Aroda , Timothy Bailey , Robert S. Busch , John B. Buse , Elena Christofides , Ralph A. DeFronzo , Bradley Eilerman , Vivian Fonseca , Adline Ghazi , Steven E. Kahn , Mark Kipnes , Dan Lender , Jonathan G. Ownby , Jean Park , Julio Rosenstock , Michael Shanik , Lance Sloan , Ron Swerdloff , Guillermo Umpierrez , Daniel Einhorn","doi":"10.1016/j.metabol.2025.156214","DOIUrl":"10.1016/j.metabol.2025.156214","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156214"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measures of Insulin Resistance (IR) Increase with Increasing BMI in a Population of Normoglycemic Working Adults 在正常血糖的工作成年人中，胰岛素抵抗（IR）随BMI的增加而增加
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156215
Judy Louie, Dov Shiffman, James B. Meigs, Lance Bare, Michael J. McPhaul
{"title":"Measures of Insulin Resistance (IR) Increase with Increasing BMI in a Population of Normoglycemic Working Adults","authors":"Judy Louie, Dov Shiffman, James B. Meigs, Lance Bare, Michael J. McPhaul","doi":"10.1016/j.metabol.2025.156215","DOIUrl":"10.1016/j.metabol.2025.156215","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156215"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the Role of Hypoxia-Induced HIF-1α/SMAD2/VEGF Signaling in Promoting M2 Polarization of Renal Macrophages for Potential Renoprotective Effects 探讨缺氧诱导的HIF-1α/SMAD2/VEGF信号在促进肾巨噬细胞M2极化中的作用及其潜在的肾保护作用
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156230
Yaya Xu, Jiayue Xu, Jiru Li, Xiangmei Kong, Haoyun Mao, Zhiyi Du, Jiahui Zan, Lili Xu, Wen Qian, Zhushengying Ma, Yueniu Zhu, Xiaodong Zhu
{"title":"Exploring the Role of Hypoxia-Induced HIF-1α/SMAD2/VEGF Signaling in Promoting M2 Polarization of Renal Macrophages for Potential Renoprotective Effects","authors":"Yaya Xu, Jiayue Xu, Jiru Li, Xiangmei Kong, Haoyun Mao, Zhiyi Du, Jiahui Zan, Lili Xu, Wen Qian, Zhushengying Ma, Yueniu Zhu, Xiaodong Zhu","doi":"10.1016/j.metabol.2025.156230","DOIUrl":"10.1016/j.metabol.2025.156230","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156230"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gender Differences in Prevalence and Clinical Correlates of Dapagliflozin-Associated Diabetic Ketosis/Ketoacidosis in Patients with Type 2 Diabetes Mellitus 2型糖尿病患者达格列净相关糖尿病酮症/酮症酸中毒患病率及临床相关因素的性别差异
IF 10.8 1区 医学
Metabolism: clinical and experimental Pub Date : 2025-06-01 DOI: 10.1016/j.metabol.2025.156231
Maosheng Lee , Yanyan Tan , Siping Peng , Shimao Zhang , Hengxia Zhao , Huilin Li
{"title":"Gender Differences in Prevalence and Clinical Correlates of Dapagliflozin-Associated Diabetic Ketosis/Ketoacidosis in Patients with Type 2 Diabetes Mellitus","authors":"Maosheng Lee , Yanyan Tan , Siping Peng , Shimao Zhang , Hengxia Zhao , Huilin Li","doi":"10.1016/j.metabol.2025.156231","DOIUrl":"10.1016/j.metabol.2025.156231","url":null,"abstract":"","PeriodicalId":18694,"journal":{"name":"Metabolism: clinical and experimental","volume":"168 ","pages":"Article 156231"},"PeriodicalIF":10.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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